Clinical trials: Tobacco Use Disorder
Adolescent Substance Use
Guiding Good Choices for Health
This study evaluates the feasibility and effectiveness of implementing Guiding Good Choices (GGC), an anticipatory guidance curriculum for parents of early adolescents, in three large, integrated healthcare systems.
- Trial name
- GGC4H (NCT04040153)
- Testing
- Guiding Good Choices
- Where
- 3 sites in United States
- Volunteers
- 3,636 people, healthy volunteers welcome
- Sponsor
- University of Washington
HIV Infections, AIDS
HIV Infection and Tobacco Use Among Injection Drug Users in Baltimore, Maryland: A Pilot Study of Biomarkers
Background: The incidence of lung cancer is quite high among people with the human immunodeficiency (HIV) virus. Frequent smoking may explain that cancer increase, given that 50% to 70% of HIV-infected people are current smokers.
- Conditions
- HIV Infections, AIDS, Lung Cancer, Tobacco Addiction
- Trial name
- NCT00491335
- Where
- United States
- Sponsor
- National Cancer Institute (NCI)
Tobacco Use Disorder
Clinical Effort Against Secondhand Smoke (CEASE) Program or Standard Care in Helping Parents Stop Smoking
RATIONALE: The Clinical Effort Against Secondhand Smoke (CEASE) program may be more effective than standard care in increasing the number of parents who stop smoking.
- Trial name
- NCT00664261
- Testing
- smoking cessation intervention, cancer prevention, counseling intervention
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- Massachusetts General Hospital
Vaping
Social Media Intervention to Stop Nicotine and Cannabis Vaping Among Adolescents
Social media based intervention to support teens in their efforts to quit vaping.
- Trial name
- NCT04707911
- Testing
- Social Media Intervention
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Nicotine Dependence
Prize Reinforcement for Smoking Cessation
Nicotine dependence is prevalent in society, cigarette smoking is associated with several known health risks, and most dependent individuals find it very difficult to stop smoking cigarettes.
- Trial name
- NCT00865254
- Testing
- Standard Treatment, Traditional Contingency Management, Early Enhanced Contingency Management
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Smoking Reduction, Tobacco Use
Promoting Smoking Cessation in Lung Cancer Screening Through Proactive Treatment
This pragmatic trial will evaluate the value of routinely providing proactive smoking cessation support to current smokers as a part of participating in lung cancer screening within Veterans Health Administration.
- Conditions
- Smoking Reduction, Tobacco Use, Tobacco Smoking, Tomography
- Trial name
- PROACT (NCT03612804)
- Testing
- Unsigned note to provider about cessation medication prescription, Proactive Telephone Counseling from VA Quitline
- Where
- 3 sites in United States
- Volunteers
- 944 people
- Sponsor
- VA Office of Research and Development
Tobacco Use Disorder
Tobacco Approach Avoidance Training for Adolescent Smokers-2
This is a two part study. In Study 2, smokers who want to quit smoking will participate in a 4 week smoking cessation program combining weekly cognitive behavioral therapy (CBT) with weekly regular-AAT or placebo-AAT training.
- Trial name
- AAT-2 (NCT01625637)
- Testing
- AAT-experiment
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Yale University
Cancer, Tobacco Use
Improving Tobacco Treatment Rates for Cancer Patients Who Smoke
The research objective is to identify a simple, pragmatic, innovative way of enhancing Tobacco Use Treatment (TUT) rates within oncology.
- Conditions
- Cancer, Tobacco Use, Smoking, Nicotine Dependence
- Trial name
- NCT04738643
- Testing
- Tobacco Use Treatment Service and Varenicline Management
- Where
- 2 sites in United States
- Volunteers
- 685 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Tobacco Dependence, Schizophrenia
The Pharmacogenetic Study , Readiness to Change, and Pharmacological Intervention for Smoking Cessation in Schizophrenia
Cigarette smoking represents a major health problem for patients suffering from schizophrenia. Compared to the general population, schizophrenic patients are significantly more likely to be addicted to nicotine.
- Trial name
- PSIAARP (NCT00495352)
- Testing
- Hihg-doseNRT, Low-dose NRT, bupropion
- Where
- Taiwan
- Volunteers
- 360 people
- Sponsor
- Yu-Li Hospital
Nicotine Dependence
Extended Cessation Treatment for Teen Smokers
This study is designed to test the efficacy of an extended smoking cessation program for teen smokers. We hypothesize that teen smokers randomized to extended treatment will have a higher abstinence rate at 52 week follow-up than…
- Trial name
- Nicoteens (NCT00459953)
- Testing
- Extended treatment
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Stanford University
Preterm Birth, Health Care Utilization
Testing Feasibility of Care Coordination and Motivational Interviewing for Women With a Recent Preterm Birth
This study continues an adaptation of care coordination to address the needs of women after preterm birth. This is a small single arm open trial designed to test intervention implementation and refine the intervention before…
- Conditions
- Preterm Birth, Health Care Utilization, Tobacco Use, Contraceptive Usage
- Trial name
- NCT05120843
- Testing
- Care coordination and motivational interviewing
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
ADHD
Prevention of Cigarette Smoking in Attention Deficit Hyperactivity Disorder (ADHD) Youth With Concerta
This study will consist of a six-week open-label treatment period with an extended duration methylphenidate (OROS MPH) followed by subsequent monthly visits for 24 months in a large sample of youths aged 12-17 who meet Diagnostic…
- Trial name
- NCT00181714
- Testing
- methylphenidate HCl (Concerta)
- Where
- United States
- Volunteers
- 203 people
- Sponsor
- Massachusetts General Hospital
Asthma, Incentives
Financial Incentives to Reduce Pediatric Tobacco Smoke Exposures
Secondhand smoke exposure (SHSe) is one of the most common and potentially modifiable environmental triggers for asthma. Financial incentivization may serve as an effective modality to reduce SHSe among pediatric asthmatics with…
- Conditions
- Asthma, Incentives, Tobacco Smoking
- Trial name
- NCT03099811
- Testing
- Incentive plan, Smoking cessation
- Where
- United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Tobacco Use Disorder
Tobacco Use Among Arab American Youth
Michigan has the 10th highest smoking rate in the nation. Smoking rates are also very high in the Middle East and in Arab American families.
- Trial name
- NCT00059514
- Testing
- Modified Project Toward No Tobacco Use
- Where
- United States
- Volunteers
- 2,300 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Nicotine Use Disorder, Tobacco Use Disorder
Evaluation of the Addictive Potential of E-Cigarettes
This study will examine the subject matter from a neurobiological and a neuropsychological vantage point to ascertain whether the e-cigarette is potentially as addictive as the traditional tobacco cigarette.
- Trial name
- EVAPE (NCT04772014)
- Where
- Germany
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Central Institute of Mental Health, Mannheim
Tobacco Dependence
Safety, Tolerability and Efficacy of the Nicotine Patch and Gum for the Treatment of Adolescent Tobacco Dependence
The purpose of this study is to test the safety, tolerability, compliance and efficacy of two different forms of nicotine replacement therapy (NRT) (the nicotine transdermal patch and the nicotine gum) in a nicotine-dependent…
- Trial name
- NCT01208935
- Testing
- Nicotine Patch, Nicotine Gum
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Tobacco Use Disorder
Evaluation of a Combined Parent-student Programme for Smoking Prevention in Berlin Schools
The purpose of this study is to evaluate the effectiveness of a combined parent-student program for smoking prevention in 7th graders in Berlin schools.
- Trial name
- BEST (NCT01306552)
- Testing
- Student-Intervention only group, Multi-component Intervention, Control Group
- Where
- Germany
- Volunteers
- 3,400 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Tobacco Smoking in Mother Complicating Pregnancy, Tobacco Use Disorder
Smoking Reduction In Gravid Substance Use Disorders
The aim of this study is to encourage smoking cessation in women with substance use disorders by providing knowledge of expired carbon monoxide.
- Conditions
- Tobacco Smoking in Mother Complicating Pregnancy, Tobacco Use Disorder, Tobacco Smoking
- Trial name
- SIGS (NCT04132232)
- Testing
- knowledge of expired maternal carbon monoxide and fetal carboxyhemoglobin levels
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Tobacco Use Disorder, Smoking Cessation
p16 Methylation for Smoking Cessation
Smoking cessation is often difficult for smokers to achieve for a variety of reasons including: difficulty with nicotine withdrawal, failure to perceive the benefits of smoking cessation, and failure to perceive the risks…
- Conditions
- Tobacco Use Disorder, Smoking Cessation, Lung Cancer
- Trial name
- NCT01038492
- Testing
- p16 Methylation and Lung Cancer Education
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Duke University
Nicotine Dependence
Bupropion Treatment for Youth Smoking Cessation
The purpose of this study is to 1) evaluate the safety and efficacy of two doses of bupropion SR (150mg/day and 300mg/day) when compared to placebo, as an aid to smoking cessation in adolescents and 2) to examine which factors…
- Trial name
- NCT00344695
- Testing
- bupropion SR
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Arizona