Clinical trials: Tooth, Impacted
Pain
Fixed-dose Combination of Oxycodone [OXIcodona] + IbuproFEN in Pain Relief After Third Molar Extraction
A clinical, multicenter, randomized, parallel-group, double-blind, double-dummy, comparative study of non-inferiority. ⚠️Study will only be conducted in research centers in Brazil (please do not send e-mail if your center is…
- Trial name
- OXIFEN (NCT05081102)
- Testing
- FDC of oxycodone 5 mg/ibuprofen 400 mg, Tylex
- Where
- Brazil
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Eurofarma Laboratorios S.A.
Adverse Childhood Experiences, Family Functioning
The THRIVE Study: Teaching Healthy Regulation in Individuals & Vulnerable Environments
The goal of this 2-arm randomized control trial is to determine the impact of a community health worker delivered coaching intervention, GRIT, on preventing the early initiation of regular use of alcohol and cannabis among…
- Trial name
- NCT06821035
- Testing
- Garnering Resilience in Traumatized youth and families (GRIT), Digital Citizenship Curriculum (DCC)
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Impacted Tooth
Application of Surgical Templates in the Surgical Exposure of Impacted Canines
The first choice therapy in case of palatally impacted canines is their exposure and orthodontic eruption to improve facial esthetics and prevent pathologies associated with impacted teeth and Temporomandibular Joint Disorders.
- Trial name
- NCT05909254
- Testing
- Palatally impacted canine exposure using a surgical guide, Palatally impacted canine exposure using the conventional free.hand method
- Where
- Hungary
- Volunteers
- 40 people
- Sponsor
- Semmelweis University
Advanced Cancers
Initiative for Molecular Profiling in Advanced Cancer Therapy (IMPACT) Trial, An Umbrella Protocol
Primary Objective The primary objective of this study is to establish a program for the molecular profiling of patients with advanced cancer, with the goals of (1) providing a comprehensive characterization of the molecular…
- Trial name
- NCT00851032
- Testing
- Molecular Profiling Analyses
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- M.D. Anderson Cancer Center
Malocclusion
An Electromyography Study Comparing the Impact of Using RMEs on Muscle Activity Among Growing Orthodontic Patients
Compare the impact of using rapid maxillary expanders on masticatory muscle activities (Masseter and Anterior Temporalis muscles) among different posterior cross-bite patient (unilateral, bilateral) as well as compare the…
- Trial name
- NCT02752347
- Testing
- Surface EMG device
- Where
- Saudi Arabia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Impacted Mandibular Third Molar
Comparison of Electrocautery and Scalpel Blade Incisions of Impacted Mandibular Third Molars
This randomized controlled trial aims to compare electrocautery and scalpel blade incisions during surgical extraction of impacted mandibular third molars.
- Trial name
- NCT07723326
- Testing
- scalpel blade incision, electrocautery incision
- Where
- Pakistan
- Volunteers
- 78 people
- Sponsor
- Riphah International University
Post Operative Pain, Acute
Saline At Different Temperatures After 3rd Molar Surgery
This double-blind, single-center, split-mouth, randomized prospective clinical trial was conducted among 48 systemically and periodontally healthy patients who had bilaterally asymptomatic mandibular third molars.
- Trial name
- NCT06741696
- Testing
- Surgical extraction, saline irrigations
- Where
- Pakistan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan
Effectiveness of the I-arch System
Clinical Performance of the I-arch System During the Initial Stage of Orthodontic Treatment
The goal of this clinical trial is to learn if the I-arch system works to align the moderately misaligned teeth in patients seeking orthodontic treatment.
- Trial name
- NCT07264127
- Testing
- The use of 0.016×0.014 copper nickel titanium arch wire during the alignment stage., Use of 0.014- then 0.016-inch heat-activated nickel titanium arch wire during the alignment stage.
- Where
- Iraq
- Volunteers
- 34 people
- Sponsor
- Tabark H. Omran
Edema, Pain
The Impact of Arnica Montana Following the Surgical Extraction of Impacted Third Molars
Aim: The aim of this study is to evaluate the action of the homeopathic plant Arnica Montana on postoperative edema, pain and trismus after surgical extraction of impacted wisdom teeth.
- Conditions
- Edema, Pain, Trismus
- Trial name
- NCT06193720
- Testing
- Arnica montana
- Where
- Lebanon
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Malocclusion
Impact of Dental Composite Viscosity on Attachment Accuracy: a Prospective Clinical Trial
The present study will be a single-center, split-mouth, randomized controlled clinical trial. Patients undergoing orthodontic treatment with Invisalign aligners will be enrolled after signing the informed consent.
- Trial name
- NCT06288386
- Testing
- GrandioSO Heavy Flow, Filtek Z350XT Flowable
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- University of Pavia
Tooth Eruption,Ectopic
Interceptive Study of Ectopic Eruption of Permanent Maxillary Canine Teeth
The purpose of this study is to see whether extraction of the primary canine tooth or extraction of both the primary canine - and the primary first molar tooth is most effective in the treatment of palatally ectopic canine teeth…
- Trial name
- NCT02675036
- Testing
- Tooth extraction
- Where
- Norway
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Tromso
HIV/AIDS
Suubi4Her: Combination Intervention for Adolescent Girls Transitioning Into Adulthood in Uganda
This study examines the impact and cost associated with Suubi4Her, an innovative combination intervention that aims to prevent HIV risk behaviors among 15-17 year-old girls living in communities heavily affected by poverty and…
- Trial name
- NCT03307226
- Testing
- Youth Development Accounts (YDA), YDA + Multiple Family Groups (MFG)
- Where
- 2 sites in Uganda
- Volunteers
- 1,260 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Diet Habit, Family Characteristics
Nutrition, Physical Activity, Mediterranean Diet Adherence, and Children's Oral Health
The main risk factors for dental caries are inadequate oral hygiene practices, cariogenic bacteria, and cariogenic diet. Among these factors, diet has a different dual relationship with dental caries.
- Conditions
- Diet Habit, Family Characteristics, Tooth Decay, Periodontal Health
- Trial name
- NCT06130189
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Ankara Medipol University
Trismus, Swelling
Comparison of Two Different Suture Knot Techniques on Post-Operative Trismus and Swelling After Impacted Third Molar Surgery
To compare the two different suture knot techniques, locked and unlocked, in terms of mean on postoperative trismus and swelling after impacted mandibular third molar surgery.
- Trial name
- Impacted molar (NCT07327762)
- Testing
- locking and non locking suture techniques, non locking suture technique
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Watim Medical & Dental College
Self-esteem, Personality
Psychological Assessment of Adults Seeking Orthodontic Treatment
Is their a association between the objective and subjective severity of a malocclusion, quality of life and self-esteem/personality (as modifier between objective/subjective severity and quality of life (cfr study Agou et al.…
- Conditions
- Self-esteem, Personality, Quality of Life, Malocclusion
- Trial name
- NCT01475773
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Lead Poisoning, Obesity
QI Study of a Practice Facilitator's Impact in Working With Clinics on Improving Dental, Lead & Obesity Measures for Children
Funded by the Ohio Department of Job and Family Services - Medicaid Technical Assistance and Policy Program (MEDTAPP), the "Child Health Excellence Center - a University-Practice-Public Partnership" (CHEC-UPPP) focuses on…
- Conditions
- Lead Poisoning, Obesity, Dental Decay
- Trial name
- NCT01739166
- Testing
- Practice-tailored intervention to increase rates of targeted services
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Cystic Fibrosis
Improving P. Aeruginosa Detection With Breath-based Diagnostics (IMPACT-Breath)
The study is a breath biomarker validation study. It is anticipated that 300 patients with cystic fibrosis (CF) from 5 clinical sites in the USA will be enrolled.
- Trial name
- IMPACT (NCT04735952)
- Where
- 7 sites in United States, Canada
- Volunteers
- 300 people
- Sponsor
- University of British Columbia
Pain, Teeth, Impacted
Evaluation of Articaine 4% Versus Mepivacaine 2% for Surgery of Molars Thirds: Clinical Trial.
The extraction of third molars, a frequent treatment in clinical dental practice, can lead patients to painful symptoms during and after surgery.
- Trial name
- NCT03384160
- Testing
- Group 1 -Pain monitor, Group 2 -Pain monitor
- Where
- Brazil
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Moderate Pain, Severe Pain
Efficacy and Safety of DIT112 in the Treatment of Moderate to Severe Pain After Dental Surgery for the Extraction of Impacted Third Molars
The purpose of this study is to evaluate the efficacy and safety of DIT112 in adolescents and adults with acute pain after dental surgery for the extraction of impacted third molars.
- Trial name
- ALIV (NCT06237231)
- Testing
- DIT112, DIPYRONE, TRAMADOL
- Volunteers
- 252 people
- Sponsor
- EMS
Dental Caries
Impact of Detecting Initial and Active Caries Lesions in Primary Teeth
The present study aims to evaluate the impact of detecting active initial caries lesions in primary teeth regarding effectiveness, cost-effectiveness, applicability (acceptability and satisfaction) and quality of life.
- Trial name
- NCT02473107
- Testing
- Advanced caries lesions detection (no activity assessment), All caries lesions detection (+activity assessment)
- Where
- Brazil
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo