Clinical trials: Tooth
White Spot Lesions [Initial Caries] on Smooth Surface of Tooth
Clinical Impact of White Tea and Wheat Grass on Color Enhancement of White Spot Lesions
The current study aimed to evaluate the color change potential of wheat grass and white tea on post orthodontic white spot lesions (WSLs).
- Trial name
- NCT06976385
- Testing
- White tea, Wheat grass solution
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Al-Azhar University
Malocclusion, Angle Class I, Malocclusion, Angle Class II
AI-Assisted Versus Conventional Orthodontic Diagnosis and Treatment Planning
This study compared an artificial intelligence-assisted orthodontic diagnostic workflow using WebCeph with a conventional clinician-based workflow.
- Conditions
- Malocclusion, Angle Class I, Malocclusion, Angle Class II, Malocclusion, Angle Class III
- Trial name
- AI-OrthoDx (NCT07690774)
- Where
- Yemen
- Volunteers
- 120 people
- Sponsor
- Ben Hafeed Dental Center
Dental Caries
ASSESSMENT OF SDF vs. GIC AND HALL TECHNIQUE
Early childhood caries (ECC) ,a global public health problem, highly prevalent and severe with life long implications is entirely preventable.
- Trial name
- NCT05117268
- Testing
- SDF Application for caries arrest, Glass ionomer restoration, Hall technique
- Where
- Pakistan
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Dental Implant, Tooth Extraction
Soft Tissue Volume Changes After Immediate Implants With Two Different Techniques
The aim is to comparatively evaluate the soft tissue volume changes that occur after tooth extraction and immediate dental implant placement using two different surgical techniques.
- Conditions
- Dental Implant, Tooth Extraction, Bone Resorption
- Trial name
- NCT04803110
- Testing
- Dental implant placement after tooth extraction
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Aula Dental Avanzada
Molar Incisor Hypomineralization
Prevalence of Molar Incisor Hypomineralization Among a Group of Egyptian Children in Fayoum Governorate Schools
Determining the Prevalence of Molar Incisor Hypomineralization Among a Group of Egyptian Children in Fayoum Governorate Schools via clinical examination.
- Trial name
- NCT04420520
- Volunteers
- 135 people
- Sponsor
- Cairo University
Evaluations, Diagnostic Self, Antimicrobial
ZnO Nanoparticles Coated Orthodontic Molar Tube
Orthodontic treatment is an elective procedure to improve the patient's dentofacial appearance. The complex design of fixed appliances provides a platform that leads to increased plaque accumulation around orthodontic brackets.
- Conditions
- Evaluations, Diagnostic Self, Antimicrobial, Orthodontic Appliance Complication, Bacterial Overgrowth
- Trial name
- ZnONPs (NCT06089720)
- Testing
- Zinc oxide nanoparticle coated orthodontic molar tubes (experimental), orthodontic molar tubes (control)
- Where
- Iraq
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Orofacial Pain, Bruxism
Effectiveness of Chlorzoxazone Versus Orphenadrine Citrate in Alleviating Bruxism Pain
To evaluate the clinical effectiveness of chlorzoxazone in comparison to orphenadrine Citrate in relieving the orofacial pain in bruxers.
- Trial name
- NCT07109882
- Testing
- Chlorzoxazone, Orphenadrine Citrate
- Where
- Iraq
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Charcot-Marie-Tooth Disease
Phase III Trial Assessing the Efficacy and Safety of PXT3003 in CMT1A Patients
The study will consist of 2 periods: Double-blind Treatment and Open-Label Extension(OLE) Period. -Double-blind Treatment Period - This will be randomized, double-blind, placebo-controlled part of the study which will be…
- Trial name
- PREMIER (NCT04762758)
- Testing
- (RS)-baclofen, naltrexone hydrochloride and D-sorbitol
- Where
- 50 sites in United States, Belgium and 7 more
- Volunteers
- 350 people
- Sponsor
- Pharnext S.C.A.
Periodontal Disease; Gingivitis; Dental Plaque; Malocclusion (Post-orthodontic Treatment)
Digital vs Conventional VFR in Post-Orthodontic Retention
This study is comparing two ways of making a retainer, the clear, removable kind worn after braces to see whether the way it's made affects gum health.
- Trial name
- NCT07760935
- Testing
- Digital Vacuum-Formed Retainer, Conventional Vacuum-Formed Retainer
- Volunteers
- 52 people
- Sponsor
- Ziauddin University
Tooth Disorder, Missing Tooth/Teeth
All-ceramic Restorations: a Retrospective and Prospective Study
The goal of this observational study is to evaluate the survival and success rate of ceramic restorations on teeth and implants done in the department of fixed prosthodontics at the CHU of Liege for the last 25 years.
- Trial name
- PROCER (NCT07110220)
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Mainjot Amélie
Dental Caries, Dental Plaque Accumulation
Miswak (Salvadora Persica) Versus a Toothbrush in Plaque Removal
The study investigates the effectiveness of a 45°-cut miswak for plaque removal compared to a toothbrush in children and assesses their preferences for these tools.
- Trial name
- NCT07409610
- Testing
- Miswak, Toothbrush
- Where
- Saudi Arabia
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Tooth Impaction, Impacted Canine, Dental Anomalies
This Systematic Review Aims to Synthesize Available Evidence Regarding the Prevalence, Anatomical Distribution, Etiological Determinants, and Diagnostic Assessment of Permanent Canine Impaction. A Systematic Search of PubMed, PubMed Central, and ScienceDirect Was Conducted for Studies Published Betw
This systematic review aimed to synthesize current evidence regarding the prevalence, anatomical distribution, etiological determinants, and diagnostic assessment of permanent canine impaction.
- Trial name
- PCI (NCT07509320)
- Where
- Romania
- Sponsor
- Dimitrie Cantemir University
Dental Caries
High-strength Glass-ionomer Dental Restorations
The purpose of this study is to extend our knowledge concerning the clinical performance of two dental filling materials in molars. The study will compare two high-strength glass-ionomer filling materials.
- Trial name
- ROCK (NCT01523613)
- Testing
- Chemfil ROCK Glassionomer restoration, Fuji IX GP Extra Glassionomer restoration
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Mathilde Peters, DMD, PhD
Class II Malocclusion
The Effect of Low-level Laser Therapy on Functional Treatment of Skeletal Class II Patients
this is a controlled clinical trial with 2 groups of patients of class II skeletal discrepancy due to mandibular retrusion one group is treated with twin block functional appliance and the other with twin block combined with low…
- Trial name
- NCT06024382
- Testing
- twin block, twin block combined with low level laser
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Mansoura University
Molar Hypomineralization
Pulpotomy in Hypominerlized Permanent Molars.
The first permanent molars in children can sometimes develop a condition called molar-incisor hypomineralization (MIH), which affects the strength and quality of the tooth structure.
- Trial name
- NCT07756216
- Testing
- Step wise pulpotomy
- Where
- Jordan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Molar Incisor Hypomineralization
Use of a Glass Ionomer Sealant in Molar Incisor Hypomineralization
Molar Incisor Hypomineralization (MIH) is a worldwide widespread qualitative developmental defect of the dental enamel with a multifactorial aetiology defined in 2001 as an "hypomineralization of systemic origin affecting one or…
- Trial name
- NCT05806398
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- IRCCS Burlo Garofolo
Pulp Necrosis, Immature Permanent Teeth
PRF and CGF Scaffolds With EDTA in Regeneration
This study evaluated the regenerative outcomes of immature permanent teeth with necrotic pulps treated using three scaffold types-blood clot, platelet-rich fibrin (PRF), and concentrated growth factor (CGF)-combined with either…
- Conditions
- Pulp Necrosis, Immature Permanent Teeth, Open Apex, Periapical Periodontitis
- Trial name
- RET-EDTA-CGF (NCT07265804)
- Testing
- Blood Clot + 5% EDTA, Blood Clot + 17% EDTA, PRF + 5% EDTA
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Gingival Hyperplasia, Dental Plaque
Clinical Efficacy of Chlorhexidine Varnish in Reducing Gingival Hyperplasia, Plaque Accumulation, and White Spot Lesions in Orthodontic Patients
This study investigates whether applying a chlorohexidine varnish (a dental coating) reduces gum overgrowth, plaque buildup, and early tooth decay (white spots) in patients with braces.
- Conditions
- Gingival Hyperplasia, Dental Plaque, Tooth Demineralization
- Trial name
- NCT07115784
- Testing
- Chlorhexidine Varnish
- Where
- Pakistan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Space Maintenance, 3D Printing
Evaluation of a 3D Printed Space Maintainer Versus the Conventional Band and Loop
The goal of this study is to evaluate whether a new 3D-printed dental device can effectively maintain space after premature loss of primary teeth in children, compared to the traditional stainless-steel device.
- Conditions
- Space Maintenance, 3D Printing, Primary Teeth
- Trial name
- NCT07161076
- Testing
- 3d Printed space maintainer, stainless steel band and loop
- Where
- Egypt
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Malocclusion, Muscle Activity
Evaluation of Muscle Activity in Unilateral Posterior Crossbite
Posterior crossbite (PCB) is defined as the presence of one or more teeth of the posterior group (canine to third molar) in an inverted buccolingual relationship, where the vestibular cusp of the upper tooth is in contact with…
- Conditions
- Malocclusion, Muscle Activity, Maxillary Expansion
- Trial name
- NCT04962685
- Testing
- Rapid Maxillary Expansion
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Universitat Internacional de Catalunya