Clinical trials: Tooth
Malocclusion, Esthetics, Dental
Effect of Finishing Clear Aligner Marginal Termination Design (Supragingival vs Juxtagingival) on Aligner Color Stability After 14 Days of Wear: A Split-Mouth Study
The goal of this clinical study is to learn whether the gumline edge design of a finishing orthodontic clear aligner affects how much the aligner's color changes after 14 days of wear.
- Trial name
- SPECTRO-ALIGN (NCT07628491)
- Testing
- Tri-layer thermoplastic finishing clear aligner
- Where
- Romania
- Volunteers
- 50 people
- Sponsor
- George Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu Mures
Gingivitis Infection, Dental Plaque
Chlorhexidine vs Essential Oil Mouthwash for Plaque Control
Dental plaque is a sticky film of bacteria that forms on teeth and can lead to gum disease if it is not removed regularly. Brushing and flossing help control plaque, but many people also use a mouthwash to help clean areas that…
- Trial name
- NCT07822256
- Testing
- Chlorhexidine Gluconate Mouthwash, Essential Oil mouthwash
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Rehman Medical Institute - RMI
Bleeding, Tooth Extraction
Effects of Tranexamic Acid Irrigation on Impacted Third Molar Surgery
Tranexamic acid (TXA) is an effective hemostatic agent used to reduce blood loss and the need for transfusion. It is a relatively safe drug with minimal significant side effects.
- Trial name
- NCT06806241
- Testing
- Tranexamic acid, saline irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Silver Diamine Fluoride
Long-term Effect of Silver Diamine Fluoride on the Dentin-Pulp Complex in Primary Teeth
Children with primary teeth with dentin carious lesions without pulp involvement, who have previously been treated with either Silver Diamine Fluoride (SDF) followed by Resin Modified Glass Ionomer or with Resin Modified Glass…
- Trial name
- NCT07586631
- Where
- Egypt
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Cairo University
Revascularization
Regeneration of Immature Teeth. Case Series
This clinical study aims to investigate the predictability of revascularization procedure of immature necrotic human permanent teeth with apical periodontitis.
- Trial name
- NCT03507556
- Testing
- Triple paste and induced bleeding, Triple Paste metronidazole, ciprofloxacin and minocycline mixed with sterile glycol
- Where
- Jordan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Dental Caries
Caries-preventive Effect of a Dentifrice Containing 5,000 Ppm Fluoride in Orthodontic Patients
AIM: To evaluate the efficacy of daily tooth brushing with high concentrated fluoride dentifrice on white spot lesion (WSL) formation in adolescents during treatment with fixed orthodontic appliances (FOA).
- Trial name
- NCT01768390
- Testing
- toothpaste containing 5,000 ppm fluoride, 1450 GCP
- Where
- Sweden
- Volunteers
- 500 people
- Sponsor
- University of Copenhagen
Dental Caries in Children, Cariostatic Agent
Cariostatic and Remineralizing Effects of Three Different Dental Varnishes
This study is a randomly, controlled, prospective in vivo study. The objective of this study is: To evaluate the cariostatic and re-mineralizing effects of Nano silver fluoride, Nano Hydroxyapatite and sodium fluoride varnishes…
- Conditions
- Dental Caries in Children, Cariostatic Agent, Resistance, Dental Caries, Fluoride Varnishes
- Trial name
- NCT04887389
- Testing
- Nano Silver Fluoride varnish, nano-hydroxyapatite varnish, sodium Fluoride Varnish
- Where
- Egypt
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Nisreen Ibrahim khan
Molar Incisor Hypomineralization, Enamel Hypoplasia
Resin Infiltration Treatment for MIH
The investigators aimed to evaluate changes in mineralisation degree, colour, and size of the lesion after Icon® in permanent teeth with MIH in 6 months.
- Conditions
- Molar Incisor Hypomineralization, Enamel Hypoplasia, Enamel Caries, Anterior Teeth
- Trial name
- NCT04685889
- Testing
- Resin infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Cavities of Teeth
An Evaluation of Protective Effects of OpalSeal™ Against Early Dental Decay in Orthodontic Patients
Fluoride is very effective in preventing dental decay (cavities) when applied in the form of a varnish on tooth surfaces. The purpose of this study is to verify if fluoride-releasing primer (OpalSeal) offers more protection…
- Trial name
- NCT03722264
- Testing
- OpalSeal, TransbondXT
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Virginia Commonwealth University
Class II Malocclusion, Class II Malocclusion, Division 1
Comparison of Early Interceptive Orthodontic Appliances (Traditional and Novel) and Later Fixed Appliance Treatment in Class II Malocclusion.
Background Approximately 15% of children have a Class II malocclusion, where the maxilla is positioned anterior to the mandible, and around 90% of these children also present with an increased overjet.
- Conditions
- Class II Malocclusion, Class II Malocclusion, Division 1, Overjet
- Trial name
- MACTWin (NCT07404696)
- Testing
- Head gear activator, Twin Block, Invisalign mandibular advancement
- Where
- 3 sites in Sweden
- Volunteers
- 144 people
- Sponsor
- Vastra Gotaland Region
Tooth Decay
Preformed Pediatric Crown Zirconia Versus Preformed Pediatric Metal Crown
Preformed metal pediatric crowns (PPCm) are currently considered the best method of restoring Primary molars affected by severe carious lesions compared to restorations made with various restorative materials (amalgams…
- Trial name
- PPC Z-M (NCT03296709)
- Testing
- PPC z, PPC m
- Where
- 4 sites in France
- Volunteers
- 101 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Dental Caries
Children's Comfort With Isolite and Rubber Dam During Dental Treatment
Effective isolation is essential for successful restorative dental treatment in children because it improves moisture control, treatment quality, and patient safety.
- Trial name
- COMFORT (NCT07718412)
- Testing
- Isolite, Rubber Dam Isolation
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Cumhuriyet University
Incomplete Root Formation of Anterior Teeth
Efficacy of Combined Scaffolds and Sodium Hypochlorite in Regenerative Endodontics of Immature Teeth
The aim of the study is to evaluate the efficacy of combinations of different scaffolds (blood clot, platelet rich fibrin, collagen) and sodium hypochlorite concentrations (0.5%- 2.5%) in regenerative endodontics of immature…
- Trial name
- NCT05803525
- Testing
- Intra-canal medication protocol
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Tanta University
Maxillary Anomaly
Evaluation of the Hybrid Rapid Maxillary Expander Assisted With Micro-osteo Perforation (MOPs) in Adult.
This study will be directed for Evaluation of the hybrid rapid maxillary expander assisted with Micro-osteo perforation (MOPs) in adults
- Trial name
- NCT06467240
- Testing
- hybrid rapid maxillary expander assisted with Micro-osteo perforation (MOPs)
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Al-Azhar University
Amelogenesis Imperfecta, Dental Fluoroses
Colorimetric, Ultra-structural and Elemental Comparison of Dental Enamel Defects
The study focuses on the analysis of enamel defects grouping together hypomineralization and hypoplasia. It focuses on 3 very characteristic enamel pathologies that are most often encountered in dental consultations: Molar…
- Conditions
- Amelogenesis Imperfecta, Dental Fluoroses, Hypomineralization Molar Incisor
- Trial name
- COLOEMAIL (NCT04704089)
- Testing
- spectrophotometer, Biological (protein analysis by western blot or mass spectrometry of matrix proteins), structural (electron microscopy) and physico-chemical analyses
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Reversible Pulpitis
Direct Pulp Capping With MTA and Calcium Hydroxide.
Aim of the study was to evaluate and compare clinical and radiographic success with MTA and calcium hydroxide as direct pulp capping materials in cariously exposed mandibular molars.
- Trial name
- NCT03284697
- Testing
- Direct Pulp Capping with Ca(OH)2, Direct Pulp Capping With MTA
- Volunteers
- 64 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Dental Caries
Comparison of Silver Modified and Conventional Atraumatic Restorative Treatment Modalities
The study is a randomized controlled trial aiming to compare the effectiveness of Silver modified atraumatic restorative technique and (SMART) and conventional atraumatic restorative technique (ART) regarding their caries…
- Trial name
- NCT03881020
- Testing
- Silver diamine Fluoride 38%, Conventional atraumatic restorative treatment
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
White Spot Lesion of Tooth, Long Term Adverse Effects
Comparison of Efficacy Of Probiotic Toothpaste and Chlorhexidine Mouthwash To Reduce S.Mutans
Orthodontic appliance causes increase in plaque accumulation, especially around brackets, wires and attachments. Advances in orthodontics in recent time have led to improved quality of appliance and treatment procedures…
- Conditions
- White Spot Lesion of Tooth, Long Term Adverse Effects, Caries, Dental, Orthodontic Appliance Complication
- Trial name
- NCT03004196
- Testing
- Probiotic Toothpaste, Dr. Reddy's Clohex, Control Group
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Peoples University, Bhanpur, Bhopal
Sleep Bruxism, Sleep Bruxism, Childhood
Evaluation of Intravascular Irradiation of Blood in Children With Sleep Bruxism
Background: The objective of this study will be to evaluate the effect of Intravascular Irradiation of Blood (ILIB) combined with myofunctional exercises for sleep bruxism in pediatrics.
- Trial name
- NCT05301452
- Testing
- Intravascular Irradiation of Blood (ILIB), Orofacial Myofunctional Therapy
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Caries, Dental
Comparing Hall vs Conventional Technique in Placing Preformed Metal Crowns From Sudan
Preformed metal crowns (PMCs) have high success rates in restoring primary molars in children but they were not generally used by dentists, especially in developing countries due to its demand of high clinical skills with the…
- Trial name
- NCT03640013
- Testing
- Hall Technique PMC
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Khartoum Centre for Research and Medical Training
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.