Clinical trials: Tooth
Tooth, Nonvital
Endodontic Regenerative Procedure for Immature Non-vital Teeth
In this clinical trial the investigators will evaluate an alternate treatment option, which was developed for teeth with incomplete roots, called Regenerative Endodontic Procedure (REP).
- Trial name
- NCT03425123
- Testing
- Regenerative Endodontic Procedure (REP)
- Where
- United States
- Sponsor
- Boston University
Dental Caries in Children
Discoloration of Carious Primary Teeth After Application of Silver Diamine Fluoride Versus Sodium Fluoride Varnish
To assess discoloration of carious primary teeth after application of silver diamine fluoride versus sodium fluoride varnish.
- Trial name
- NCT03557996
- Testing
- Silver Diamine Fluoride, Sodium Fluoride Varnish
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cairo University
Oral Health Related Quality of Life (OHRQoL), Early Childhood Caries (ECC)
Assessment of Oral Health-Related Quality of Life in Preschool-Aged Children in Alto Alentejo
The observational study aims to improve understanding of Oral Health-Related Quality of Life (OHRQoL) among preschool children in the District of Portalegre, Portugal, by examining the roles of sociodemographic, behavioral, and…
- Conditions
- Oral Health Related Quality of Life (OHRQoL), Early Childhood Caries (ECC), Traumatic Dental Injuries, Gingivitis
- Trial name
- NCT07648121
- Where
- Portugal
- Volunteers
- 454 people, healthy volunteers welcome
- Sponsor
- University of Lisbon
Dental Caries
Dietary Analysis for Caries Prevention in Children Using a Computer Software
Children will be recruited from the pediatric dentistry clinic of Marquette University at their first or recall appointment and will be asked to fill a questionnaire regarding their dietary habits.
- Trial name
- NCT02375763
- Testing
- Software instruction
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Marquette University
Dental Caries
Efficacy of Hall Technique in Atypical Lesions on Primary Teeth
Atypical carious cavities could be defined as carious lesions in more than 2 surfaces of the same tooth. Dental practitioners have shown difficulties related to material's maintenance in such type of cavities and therefore…
- Trial name
- SLM2078 (NCT02782390)
- Testing
- Dental Restoration with Stainless Crown, Dental Restoration with Composite Resin
- Where
- Brazil
- Volunteers
- 364 people
- Sponsor
- Faculty Sao Leopoldo Mandic Campinas
Dental Caries Class II
A Clinical Assessment of Glass Carbomer Cement
This study will evaluate the clinical performance of glass carbomer cement restorations in restoring proximal lesions in primary molars compared to that of resin modified glass ionomer cement and composite resin restorations.
- Trial name
- NCT03030690
- Testing
- Glass Carbomer Cement, Composite Resin, Resin Modified Glass Ionomer Cement
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
White Spot Lesions [Initial Caries] on Smooth Surface of Tooth
EFFICACY OF BIOMIN FLUORIDE VERSUS SODIUM FLUORIDE VARNISHES, WITH AND WITHOUT DIODE LASER ON WHITE SPOT LESIONS REMINERALIZATION IN PRIMARY TEETH.
The goal of this randomized controlled clinical trial is to assess and compare the remineralizing effect of Biomin fluoride varnish and conventional 5% sodium fluoride varnish (Duraphat), with and without adjunctive low-level…
- Trial name
- NCT07845110
- Testing
- BioMin® fluoride varnish: 5% NaF varnish incorporating bioactive glass (calcium/phosphate releasing)., (BioMin® + Diode Laser), (Duraphat varnish + Diode laser)
- Where
- 2 sites in Egypt
- Volunteers
- 80 people
- Sponsor
- Yassmin Mohamed
Class II Malocclusion
Evaluation of Skeletal and Dental Effect of the New Hybrid Aesthetic Functional Appliance
use new hybrid aesthetic functional appliance for treatment of class II div 1 malocclusion.
- Trial name
- NCT06209125
- Testing
- hybrid aesthetic functional appliance
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Class II Malocclusion, Division 1
Pain, Discomfort, and Acceptance During Using Electrical Stimulation to Accelerate Orthodontic Teeth Movement
Forty patients with class II division 1 malocclusion who will require extraction of the upper first premolars as a part of the orthodontic treatment plan will be invited to participate in the study.
- Trial name
- NCT05920525
- Testing
- Electrical stimulation, Traditional retraction of the front upper teeth
- Where
- Syria
- Volunteers
- 40 people
- Sponsor
- Damascus University
Class III Malocclusion
Palatal Versus Buccal Protraction Using Plates Assisted With Facemask in Growing Class III Patients
to compare Palatal and buccal protraction using plates assisted with facemask in growing class III patients
- Trial name
- NCT06452368
- Testing
- facemask
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Dental Caries
The Behaviour of Dental Nurses Applying Fluoride Varnish to Young Children
The behaviour of 12 dental nurses seeing 600 nursery school children in East Scotland will be video-taped to determine the interaction patterns adopted by the staff in the application of a fluoride varnish to the surfaces of the…
- Trial name
- BEHAVE (NCT00881790)
- Testing
- Fluoride varnish
- Where
- United Kingdom
- Volunteers
- 509 people, healthy volunteers welcome
- Sponsor
- University of St Andrews
Class II Malocclusion
Maxillary Arch Distalization With Infrazygomatic Crest Miniscrews for Class II Malocclusion
This prospective clinical study will evaluate the effects of moving the entire upper dental arch backward using infrazygomatic crest miniscrews in participants with Class II malocclusion.
- Trial name
- NCT07875660
- Testing
- Infrazygomatic Crest Miniscrews
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Mansoura University
Malocclusion
Digital vs. Conventional Indirect Bonding.
This randomized split-mouth clinical trial will compare digital and conventional indirect bonding techniques for fixed orthodontic bracket placement in adolescent patients requiring treatment in both dental arches.
- Trial name
- NCT07692880
- Testing
- digital indirect bonding technique, conventional indirect bonding technique
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Dental Caries
Caries Inhibitory Effect of Nano Silver and Tri Calcium Phosphate Varnishes Among Visually Impaired Children
Assessment of pH,streptococcus mutants count, lactobacillus count and immunoglobulin A among visually impaired children after nano silver varnish application it tri calcium phosphate phosphate varnish application
- Trial name
- Prevention (NCT06576960)
- Testing
- Nano silver fluoride varnish and tri calcium phosphate varnish
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Hadeer Mohammed Abd El wahab
Orthodontic Appliances, Removable, Orthodontic Appliance Complication
Microbial Adherence, Surface Roughness, Effectiveness and Impact on Patients Between Conventional and 3D Printed Twin Block Appliances
The Twin Block appliance is a removable orthodontic appliance that is used to help correct a backward positioned lower jaw in growing children.
- Conditions
- Orthodontic Appliances, Removable, Orthodontic Appliance Complication, Class II Malocclusion, Division 1
- Trial name
- NCT06944860
- Testing
- Conventional TBA, 3D TBA
- Where
- Malaysia
- Volunteers
- 32 people
- Sponsor
- University of Malaya
Class II Malocclusion
Comparative Effect of Conventional and 3D-printed Twin Block Appliances on Soft Tissue Changes
: To evaluate the effectiveness of functional device treatment using both 3D-printed and conventional Twin Block appliances on soft tissue changes during growth modification in Class II malocclusion.
- Trial name
- Clinic Radiogr (NCT07795138)
- Testing
- Twin Block
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Child Behavior, Dental Caries
Midazolam and Ketamine Effect Administered Through the Nose for Sedation of Children for Dental Treatment
Randomised clinical trial to test the efficacy, safety and cost-effectiveness of sedatives; masked, controlled, parallel design with three arms, phase 4.
- Trial name
- NASO (NCT02447289)
- Testing
- Intranasal ketamine, Oral ketamine, Intranasal midazolam
- Where
- Brazil
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Molar Incisor Hypomineralization
Effect of Low-intensity Laser and Photodynamic Therapy on Infected Dentin of Permanent Teeth With MIH
The objective of this research was to evaluate the clinical effect of photodynamic therapy on dentin infected by caries lesion in permanent teeth with Molar Incisor Hypomineralization (MIH).
- Trial name
- NCT03826810
- Testing
- aPDT, ART
- Where
- Brazil
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Charcot Marie Tooth Disease, Inherited Peripheral Neuropathy
Disability Severity Scale (DSI) and Hereditary Motor and Sensory Neuropathy Overall Disability Scale (HMSN-R-ODS)
The purpose of this research study is to create and validate two patient reported outcome (PRO) questionnaires. PRO questionnaires ask questions that help to measure disability in patients with inherited neuropathies.
- Trial name
- DSI and HMSN (NCT02194010)
- Where
- 3 sites in United States, United Kingdom
- Volunteers
- 563 people
- Sponsor
- University of Iowa
Cavities of Teeth
Effectiveness of Silver Diamine Fluoride (SDF) in Arresting Cavitated Caries Lesions
This trial is a Phase III, multisite, randomized, placebo-controlled trial, with two parallel groups. The groups are SDF or placebo and they are applied every 6 months.
- Trial name
- NCT03649659
- Testing
- Silver Diamine Fluoride
- Where
- 3 sites in United States
- Volunteers
- 830 people
- Sponsor
- University of Michigan
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