Clinical trials: Tooth
Primary Teeth
Clinical Evaluation of Compomer and Composite Class II Restorations in Primary Molars: 24 Months Results
It was aimed to evaluate the clinical performance of resin-hybrid composite and compomer materials in primary molars over a 2-year period.
- Trial name
- NCT04678141
- Testing
- Dyract XP (Dentsply De Trey), Kerr Herculite Classic (Kerr Corporation),R&D Series NOVA(Kuraray Medical Inc) Clearfil TM SE Bond (Kuraray Medical),Hydrocal LC (Medicept Dental)
- Where
- Turkey (Türkiye)
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Plaque Induced Gingival Disease, Oral Health
Effect of Benzydamine Hydrochloride Mouthrinse on Plaque Accumulation in Periodontally Healthy Female Subjects
The goal of this clinical trial is to evaluate the effect of a mouthrinse containing an active ingredient benzydamine hydrochloride in the absence of daily oral hygiene.
- Trial name
- BHCl-PLAQUE (NCT07565766)
- Testing
- Benzydamine hydrochloride mouthrinse
- Where
- Croatia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Endodontic Disease, Root Canal Infection
Comparison of Antibacterial Efficacy of Three Final Irrigants
This study was conducted to determine the antibacterial affect of three different solutions used as final irrigant during endodontic therapy.
- Trial name
- NCT03853200
- Testing
- QMix Root Canal Irrigant, 17%EDTA+2%Chlorhexidine, EDTA
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Charcot Marie Tooth Disease, DIFGAN
Genotype/Phenotype Correlation of MORC2 Mutations
The Microrchidia CW-type zinc finger 2 (MORC2) gene encodes a protein expressed in all tissues and enriched in the brain. It is involved in Charcot-Marie-Tooth disease, with mire than 30 families presenting MORC2 mutations.
- Conditions
- Charcot Marie Tooth Disease, DIFGAN, Developmental Delay (Disorder), Impaired Growth
- Trial name
- PhenoMORC2 (NCT07038239)
- Testing
- Skin biopsy, Blood sample
- Where
- 12 sites in France
- Volunteers
- 45 people
- Sponsor
- Hospices Civils de Lyon
Dental Caries, Pulpitis
Comparison of Mineral Trioxide Aggregate (MTA) and 20% Formocresol (FC) in Pulpotomized Human Primary Molars
This prospective clinical randomized controlled trial is established to compare the clinical, radiographic, and histological treatment outcomes between MTA and FC in pulpotomized human primary molars at 6, 12, 18, 24 month…
- Trial name
- NCT00972556
- Testing
- Gray Mineral Trioxide Aggregate (GMTA), Diluted (20%) Formocresol (DFC)
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Malocclusion
A Comparison of the Alignment Achieved Using Computer-guided Indirect Bonding of Orthodontic Brackets to Conventional Appliance Placement
Technological advances have made computer aided orthodontic treatment planning possible. 3D dental scanners and software make it possible to design and approve the outcome before treatment begins.
- Trial name
- NCT02221856
- Testing
- Motion View, Conventional Orthodontic Treatment
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Harvard School of Dental Medicine
Dental Caries
A Clinical Trial to Assess the Safety and the Anti-caries Efficacy of COL 101 (Arginine) Non-fluoride Dentifrices in Comparison With 0.24% Sodium Fluoride (1100 Ppm F) Dentifrice Control in 10 to 14-year-old Children
The objective of this study is to assess the safety and to evaluate the anti-caries efficacy of COL101 (arginine) non-fluoride dentifrices compared to a 0.24% sodium fluoride dentifrice in 10-14 year-old children over a one year…
- Trial name
- NCT04750902
- Testing
- 0.24% Sodium Fluoride Dentifrice, 1.5% Arginine Dentifrice, 4.0% Arginine Dentifrice
- Where
- 9 sites in United States, Puerto Rico
- Volunteers
- 2,025 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dental Caries in Children
Correlation Between Dental Caries Prevalence in Primary Teeth and First Permanent Moilar of Children in Mixed Dentition Stage
to find the clinical relation between caries experience in primary teeth and first permanent molar in mixed dentition stage using def index for primary teeth , DMF index for first permanent molars and to find the clinical…
- Trial name
- NCT04618731
- Testing
- caries prevalence def ,DMF
- Volunteers
- 1,000 people
- Sponsor
- Cairo University
Antimicrobial Photodynamic Therapy
The Effect of Antimicrobial Photodynamic Therapy on the Success of Root Canal Treatment
The decontamination of the root canal system from pathological microflora is essential for the success of endodontic treatment. Mechanical instrumentation and irrigation solutions, known as the chemomechanical process, are…
- Trial name
- NCT06634745
- Testing
- Standard Needle Irrigation (SNI), Passive Ultrasonic Irrigation (PUI, EndoActivator (EA)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Mandibular Prognathism
Patient Satisfaction Vertical Ramus Osteotomy Patient Specificosteosynthesis Fixation Versus MMFmandibular Prognanthism
Two groups with mandibular prognanthism indicated for mandibular setback by intraoral vertical ramus osteotomy . first group will fixed with maxillomandibular fixation and the second group will fixed by customized plate
- Trial name
- NCT03855072
- Testing
- customized fixation plate, maxillomandibular fixation
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Bruxism, Stress
Association Between Child and Parental Stress and Bruxism in Children Aged 8-11 Years
This prospective observational case-control study aims to evaluate the association between perceived stress levels in children and their parents and the presence of clinically diagnosed bruxism in children aged 8-11 years.
- Conditions
- Bruxism, Stress, Parent Stress, Parent and Child Stress
- Trial name
- NCT07433595
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Dental Caries, Oral Health
Effect of Probiotics Containing Yogurts on the Composition of Biofilms in Patients Under Orthodontic Treatment
Aim: To assess in vivo if the intake of yogurt containing Bifidobacterium animalis ssp. lactis DN- 1173010 probiotic for a period of 2 weeks affects the salivary levels or biofilms of mutans streptococci and the lactobacilli of…
- Trial name
- NCT01657539
- Testing
- Yogurt containing probiotics
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Dental Malocclusion
Validation of Dental Malocclusion Schematic Representations for Early Orthodontic Treatment
Dental occlusion is the reciprocal confrontation of the two dental arches. The child has two set of temporary and permanent teeth and passes through different stages of dentition during which dental, skeletal or functional…
- Trial name
- CHARTE-ODF (NCT03991221)
- Testing
- Dental Exam, Orthodontics consult, Call back at 6 month
- Where
- 11 sites in France
- Volunteers
- 659 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Dental Caries, Early Childhood Caries
Oral Health and Dental Caries Prevention Intervention for Children in Romania
During 2019-2020, the National Oral Health Survey evaluated a significant sample of children aged 5, 6 and 12 years, gathering baseline data on oral health.
- Conditions
- Dental Caries, Early Childhood Caries, Quality of Life
- Trial name
- Smilebright (NCT06441500)
- Testing
- Daily tooth brushing programme
- Where
- 5 sites in Romania
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy "Victor Babes" Timisoara
Dental Anxiety
Effectiveness of Auricular Acupuncture in Reducing Dental Anxiety and Pain Perception During Orthodontic Extractions Among Adolescents
This prospective, randomised, double-blinded cross-over study aims to compare the effectiveness of auricular acupuncture (AA) with placebo sham acupuncture (PSA) in reducing dental anxiety, pain perception and physiological…
- Trial name
- NCT06434844
- Testing
- Auricular acupunctures
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Periapical Diseases
Use of Mineral Trioxide Aggregate in the Treatment of Traumatized Teeth
Traumatic tooth injuries are common in children and adolescents, and often result in pulpal necrosis and the development of periapical lesions.
- Trial name
- NCT02625298
- Testing
- ProRoot MTA, MTA+ Cerkamed
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Association of Paediatric and Preventive Dentists of Serbia
Dental Caries, Pulpotomy
BiodentineTM Versus Formocresol Pulpotomy Technique in Primary Molars
The objective of this clinical study was to prospectively compare the clinical and radiographic success rates of BiodentineTM pulpotomies versus formocresol pulpotomies in children vital primary molars.
- Trial name
- NCT03779698
- Testing
- BiodentineTM, Formocresol
- Where
- Saudi Arabia
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Class II Division 1 Malocclusion
Effect of Modified Twin Block in Skeletal Class II Growing Females With Mandibular Deficiency
The aim of this study is to evaluate the treatment effects of conventional twin block appliance versus modified twin block appliance in the treatment of patients in growing stage having skeletal class II division 1 with…
- Trial name
- NCT03635463
- Testing
- twin block appliance, modified twin block appliance
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tooth Movement
Evaluation of Treatment Outcome of Lower Incisors Crowding Using Clear Aligners With Laser Acceleration .
The present study will be performed to evaluate the effect of low-level laser therapy (LLLT) on the rate of orthodontic tooth movement through the correction of lower incisors crowding using clear aligners
- Trial name
- NCT06526871
- Testing
- Low-Level Laser acceleration, clear aligner therapy
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Huda Abdelhakim
Endodontically Treated Teeth
Clinical Performance of the Indirect Resin Composite Restorations in Endodontically Treated Teeth
Does the cuspal reduction during cavity preparation for indirect resin composite restorations in endodontically treated teeth increase the clinical performance when compared to cavities prepared without cuspal reduction?
- Trial name
- NCT04561167
- Testing
- Cuspal reduction in MOD cavity in endodontically treated teeth, No cuspal reduction in MOD cavity in endodontically treated teeth
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
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