Clinical trials: Tooth Abnormalities
Supernumerary Teeth
Prevalence of Erupted Supernumerary Teeth Among a Group of Egyptian Children Aged From Six to Fifteen Years Old
The purpose of this study is to assess the prevalence of erupted supernumerary teeth among a group of Egyptian children aged from 6-15 years old attending the Outpatients' clinic of Pediatric Dentistry and Dental Public Health…
- Trial name
- NCT03650634
- Where
- Egypt
- Volunteers
- 604 people, healthy volunteers welcome
- Sponsor
- Cairo University
Molar Incisor Hypomineralization
HYPERSENSITIVITY IN MOLAR INCISOR HYPOMINERALISATION USING LOW LEVEL LASER IN CHILDREN
Molar Incisor Hypomineralisation (MIH) is a qualitative defect of enamel that shows asymmetrically involvement of one to four on first permanent molars (FPM) with or without incisor teeth involvement.
- Trial name
- NCT06154733
- Testing
- Photobiomodulation usinf low level laser therapy, Resin-based sealant, Glass ionomer sealant
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Charcot-Marie-Tooth Disease, Type Ia
High Dose Ascorbic Acid Treatment of CMT1A
This study will look at the impact of ascorbic acid (Vitamin C) on the progression of disease in people with CMT1A as compared to volunteers receiving a placebo.
- Trial name
- NCT00484510
- Testing
- Ascorbic acid (Vitamin C)
- Where
- 3 sites in United States
- Volunteers
- 110 people
- Sponsor
- Wayne State University
Premature Loss of Primary Teeth
Effect of Fixed and Removable Space Maintainer on Some Salivary Parameters: An In-Vivo Study
The aim of this study is to evaluate and compare the effect of lower lingual holding arch space maintainer versus removable partial denture space maintainer on some salivary parameters (salivary flow rate, pH, viscosity and…
- Trial name
- NCT06147609
- Testing
- lower lingual holding arch space maintainer, Removable partial denture space maintainer
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Hypomineralization, Tooth
ART Compared to the Hall Technique for Management HSPM
Aims: Evaluation of treatment success on HSPM-affected molars after ART and Hall technique. comparison of pain during treatment with ART and Hall technique in HSPM.
- Trial name
- NCT05816096
- Testing
- Hall technique, ART
- Where
- Syria
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Latakia University
Fluoride Poisoning, Hemoglobin
Using Eggshell Calcium to Mitigate Fluorosis in Ethiopia
Mothers and young children in rural Ethiopia lack sufficient nutrition, and a compounding factor is presence of high levels of fluoride (> 5-10 mg/day) affecting body functions.
- Conditions
- Fluoride Poisoning, Hemoglobin, Underweight, Stunting
- Trial name
- NCT03355222
- Testing
- Promotion of chicken eggs
- Where
- Ethiopia
- Volunteers
- 270 people
- Sponsor
- University of Saskatchewan
Dental Caries in Children, Tooth Erosion
3D Scanning as an Advanced Tool for Identifying Tooth Lesions in Children
This study focuses on assessing dental caries, erosive tooth wear, and fluorosis in primary teeth using a 3D intraoral digital scanner.
- Conditions
- Dental Caries in Children, Tooth Erosion, Fluorosis, Dental, Dental Caries
- Trial name
- NCT06829550
- Testing
- indirect- 3D digital scanning
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Indiana University
Tooth Impaction, Impacted Canine, Dental Anomalies
This Systematic Review Aims to Synthesize Available Evidence Regarding the Prevalence, Anatomical Distribution, Etiological Determinants, and Diagnostic Assessment of Permanent Canine Impaction. A Systematic Search of PubMed, PubMed Central, and ScienceDirect Was Conducted for Studies Published Betw
This systematic review aimed to synthesize current evidence regarding the prevalence, anatomical distribution, etiological determinants, and diagnostic assessment of permanent canine impaction.
- Trial name
- PCI (NCT07509320)
- Where
- Romania
- Sponsor
- Dimitrie Cantemir University
Collagen Degeneration
Type I Collagen Fragments in the GCF and Saliva During OTM
Investigate the levels of type I Collagen fragments ICTP and CTX in GCF and saliva during initial leveling and alignment of the teeth in a sample of adolescents undergoing orthodontic treatment.
- Trial name
- NCT05020431
- Testing
- Biological measuring of collagen fragments biomarker during orthodontic tooth movement
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Molar Incisor Hypomineralization
Sealants in Molars Affected by Molar-Incisor Hypomineralization
Aim: To evaluate the clinical survival of fluoride sealants applied in first permanent molars affected by Molar-Incisor Hypomineralization (MIH).
- Trial name
- NCT02794116
- Testing
- Conventional Sealants, Resin Sealants
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Paraná
Maxillary Deficiency, Cleft Lip and Palate
Evaluation of Maxillary Expansion Using Clear Aligners' Therapy in Patients With Cleft Lip and Palate at the Mixed Dentition Stage
The goal of this clinical trial is to learn if the aligners can expand upper dental arch in patients with cleft lip and palate at age of 6-8 years old to correct their collapsid archs.
- Trial name
- Pilot (NCT06994754)
- Testing
- clear aligners
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Cairo University
Peroneal Muscular Atrophy
Genetics of Charcot-Marie-Tooth Dystrophy and Related Diseases
This is a cross-sectional study to clarify the gene lineage distribution of CMT genes in CMT patients in my country, draw a frequency map of CMT gene distribution, and assist in determining the genetic diagnosis strategy of CMT…
- Trial name
- NCT04967716
- Testing
- basic information, venous blood test
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University Third Hospital
Molar Incisor Hypomineralization
Effects of Different Remineralization Agents on Molar Incisor Hypomineralization Defects: a Randomized Clinical Study
The aim of this study was to present a comparative evaluation of the long-term efficacy of fluoride varnish( Flúor protector), Clinpro™ White Varnish and pastes containing CPP-ACP in the remineralization of creamy-white and…
- Trial name
- NCT06362681
- Testing
- Fluoride
- Where
- Mexico
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Mexico
Congenital Cataract, Tooth Abnormalities
Associations Between Dental Anomalies and Ocular, Cutaneous and Skin Appendages Features
Considering recent literature, it is possible to hypothesise a link between dental anomalies and ocular and/or cutaneous findings, given the existence of shared genetic and developmental mechanisms between these two anatomical…
- Conditions
- Congenital Cataract, Tooth Abnormalities, Ocular Pathologies
- Trial name
- NCT06950619
- Testing
- Whole Genome Sequencing, Cephalometric tracing
- Where
- 2 sites in Italy
- Volunteers
- 5 people
- Sponsor
- University of Pavia
X-linked Hypophosphatemia (XLH)
Prevention of Spontaneous Dental Abscesses in Children With X-linked Hypophosphatemia : a RCT
This study is a prospective, randomized, single-blind, split-mouth, national multicenter trial, comparing the efficacy of a self-etch adhesive system combined (SAM) with a flowable composite to that of a fluoride varnish for the…
- Trial name
- PRADEX (NCT04872907)
- Testing
- adhesive system, fluoride varnish, flowable composite
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Molar Incisor Hypomineralization
Evaluation of Three Different Minimally Invasive Techniques for Management of Enamel Opacities in Patients With Molar Incisor Hypomineralization "Randomized Controlled Clinical Trial"
The controlled clinical trial will be done to evaluate Resin infiltration, Resin modified glass ionomer varnish and Light cured giomer varnish as minimally invasive techniques for management of enamel opacities of patients with…
- Trial name
- NCT06135272
- Testing
- Resin infiltration, Resin modified glass ionomer varnish, Light cured giomer varnish
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Molar Incisor Hypomineralization
The Effect of Molar Incisor Hypomineralisation on the Stomatognathic System
This study aims to examine whether children with Molar Incisor Hypomineralization (MIH) are more likely to have problems with the jaw joint and chewing muscles.
- Trial name
- NCT06951139
- Testing
- Ultrasound and Shear Wave Elastography
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Ozge Gungor
Fluorosis, Dental, Fluorosis
Design of a Multicomponent Intervention to Reduce the Risk of Exposure Fluorine
Introduction Systemic exposure to fluoride is a significant challenge for global public health; this is because although fluoride prevents dental caries, prolonged exposure to high concentrations can cause adverse effects on…
- Trial name
- NCT07232888
- Testing
- multicomponent intervention, Conventional intervention
- Where
- Colombia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universidad Antonio Nariño
Molar Incisor Hypomineralization, Dental Caries
Silver Diamine Fluoride and Papain-Based Gel for Management of MIH-affected Molar in Paediatric Patients
Molar incisor hypomineralization (MIH) is a developmental defect of enamel affecting the first permanent molar and frequently the incisors with a prevalence of 16-16.9% in Malaysia.
- Conditions
- Molar Incisor Hypomineralization, Dental Caries, Hypomineralization of Enamel
- Trial name
- NCT04710927
- Testing
- Silver Diamine Fluoride, Papain-Based Gel, High Viscosity Glass Ionomer Cement (HVGIC)
- Where
- Malaysia
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Tooth Disorder, Missing Tooth/Teeth
All-ceramic Restorations: a Retrospective and Prospective Study
The goal of this observational study is to evaluate the survival and success rate of ceramic restorations on teeth and implants done in the department of fixed prosthodontics at the CHU of Liege for the last 25 years.
- Trial name
- PROCER (NCT07110220)
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Mainjot Amélie