Clinical trials: Tooth Abnormality
Molar Incisor Hypomineralization
Effects of Different Remineralization Agents on Molar Incisor Hypomineralization Defects: a Randomized Clinical Study
The aim of this study was to present a comparative evaluation of the long-term efficacy of fluoride varnish( Flúor protector), Clinpro™ White Varnish and pastes containing CPP-ACP in the remineralization of creamy-white and…
- Trial name
- NCT06362681
- Testing
- Fluoride
- Where
- Mexico
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Mexico
Caries, Dental, Fluorosis, Dental
Dental Fluorosis Risk by the Use of Acidulated Fluoride Dentifrice
This research aimed to evaluate the risk of dental fluorosis by using an experimental fluoridated acidulated dentifrice compared to conventional dentifrices in two-to-four-year-old children residing in a non fluoridated area by…
- Trial name
- NCT03761485
- Testing
- Use of Dentifrice Fluoride
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- Federal University of Paraíba
Molar Incisor Hypomineralization, Enamel Hypoplasia
Resin Infiltration Treatment for MIH
The investigators aimed to evaluate changes in mineralisation degree, colour, and size of the lesion after Icon® in permanent teeth with MIH in 6 months.
- Conditions
- Molar Incisor Hypomineralization, Enamel Hypoplasia, Enamel Caries, Anterior Teeth
- Trial name
- NCT04685889
- Testing
- Resin infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Molar-Incisor Hypomineralization
Single Gene Polymorphisms Associated With Molar-Incisor Hypomineralization
The genetic factors associated with Molar-Incisor Hypomineralization (MIH), a dental condition affecting permanent molars in individuals aged 8-13.
- Trial name
- NCT06165055
- Testing
- DNA Sample Collection + DNA genotyping
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Marmara University
Molar Incisor Hypomineralization, Hypersensitivity
Intraosseous Local Anesthesia System in Children With Molar Incisor Hypomineralization
The goal of this clinical trial is to compare in effectiveness of intraosseous anesthesia and inferior alveolar block anesthesia in children with molar incisor hypomineralization (MIH).
- Conditions
- Molar Incisor Hypomineralization, Hypersensitivity, Composite Restoration
- Trial name
- NCT06461143
- Testing
- %4 articaine with 1:200 000 adrenaline
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Supernumerary Teeth
Prevalence of Erupted Supernumerary Teeth Among a Group of Egyptian Children Aged From Six to Fifteen Years Old
The purpose of this study is to assess the prevalence of erupted supernumerary teeth among a group of Egyptian children aged from 6-15 years old attending the Outpatients' clinic of Pediatric Dentistry and Dental Public Health…
- Trial name
- NCT03650634
- Where
- Egypt
- Volunteers
- 604 people, healthy volunteers welcome
- Sponsor
- Cairo University
Anodontia
Linkage and Identification of (a) Candidate Gene(s) for Tooth Disorders
The congenital absence of teeth, commonly referred to as hypodontia or tooth agenesis, is a common developmental anomaly of human dentition that affects approximately 20% of the population.
- Trial name
- NCT00026026
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Center for Research Resources (NCRR)
Molar Hypomineralization, Incisor, Fissure Sealant
Clinical Evaluation of Two Fissure Sealants (Resin Based Versus Giomer Fissure Sealants) on Molar Incisor Hypominerlisation Affected Permanent Molars (RCT)
This study aims to compare the effect of two types of fissure sealant a resin based and giomer based in molar incisor hypominerlisation first permanent molars
- Conditions
- Molar Hypomineralization, Incisor, Fissure Sealant, Resin Based Sealers
- Trial name
- MIH RCT (NCT07732790)
- Testing
- Resin based fissure sealant (Fisseal), Giomer based fissure sealant ( Beautisealant)
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- National Research Centre, Egypt
Molar Incisor Hypomineralisation, Enamel Hypoplasia
Effect of Resin Infiltration on Hypersensitivity and Satisfaction in Children With Enamel Defects
This study evaluates the effect of resin infiltration on dental sensitivity, quality of life, and satisfaction in children aged 7-14 with enamel defects in their front teeth.
- Conditions
- Molar Incisor Hypomineralisation, Enamel Hypoplasia, Dental Hypersensitivity
- Trial name
- NCT07118111
- Testing
- Resin infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gizem Tıraşçı
Molar Incisor Hypomineralization, Oral Health
Prevalence, Etiology and Effects on Oral Health and Life Quality of Molar Incisor Hypomineralization
Molar incisor hypomineralization (MIH) can lead to many clinical conditions and affect oral health-related quality of life (OHRQoL).
- Conditions
- Molar Incisor Hypomineralization, Oral Health, Child, Only, Pediatric ALL
- Trial name
- NCT05779332
- Testing
- survey application
- Where
- Turkey (Türkiye)
- Volunteers
- 655 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Ankyloglossia, Oral Mucoceles
The Effect of Pre-emptive Analgesia on the Postoperative Pain in Children Undergoing Pediatric Stomatology Day Surgeries
The aim of this double-blinded, randomized, controlled trial was to test whether pre-emptive analgesia with ibuprofen suppository is effective for children undergoing pediatric stomatology day surgeries in the postoperative…
- Conditions
- Ankyloglossia, Oral Mucoceles, Supernumerary Teeth
- Trial name
- NCT05878262
- Testing
- ibuprofen suppository
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Molar Incisor Hypomineralization, Fissure Sealant
Pre-etched Bioactive Versus Resin- Based Fissure Sealant for Permanent Molars Affected With Molar Incisor Hypomineralization (MIH).
This study aims to evaluate and compare the clinical performance of pre-etched bioactive fissure sealants to conventional RBFS in permanent molars affected by MIH in terms of retention, marginal integrity, caries prevention…
- Trial name
- NCT07504614
- Testing
- Pre-etched Bioactive Sealant, Conventional Resin-based Sealant
- Where
- Jordan
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Congenital Heart Defect, Dental Caries in Children
Oral Health Intervention Program for Children With Congenital Heart Defects
Background: Children with congenital heart defects (CHD) are reported to have poorer oral health compared with healthy children.
- Conditions
- Congenital Heart Defect, Dental Caries in Children, Dental Erosion, Dental Plaque
- Trial name
- NCT03311438
- Testing
- Oral health intervention program
- Volunteers
- 75 people
- Sponsor
- University of Bergen
Vitamin D Deficiency, Dental Caries
Maternal Vitamin D Levels in Pregnancy and Dental Caries in Children
The main aim of this study is to investigate potential associations between maternal pre- and postnatal vitamin D level and oral health outcomes (caries and developmental defects of enamel) in their children at 7-9 years of age.
- Conditions
- Vitamin D Deficiency, Dental Caries, Dental Enamel Hypoplasia
- Trial name
- NCT03273725
- Testing
- Dental examination including taking a saliva sample.
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Tannhelsetjenestens Kompetansesenter Midt-Norge
Dental Caries, Dental Fluorosis
Anticaries Potential and Fluorosis Risk From Different Fluoride Toothpastes
Fluoride toothpaste has been associated not only with declining dental caries prevalence but also with an increase in dental fluorosis.
- Trial name
- NCT01589991
- Testing
- Toothpaste
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Molar Incisor Hypomineralization
Prevalence of Molar Incisor Hypomineralization Among a Group of Egyptian Children in Fayoum Governorate Schools
Determining the Prevalence of Molar Incisor Hypomineralization Among a Group of Egyptian Children in Fayoum Governorate Schools via clinical examination.
- Trial name
- NCT04420520
- Volunteers
- 135 people
- Sponsor
- Cairo University
Tooth Disorder, Missing Tooth/Teeth
All-ceramic Restorations: a Retrospective and Prospective Study
The goal of this observational study is to evaluate the survival and success rate of ceramic restorations on teeth and implants done in the department of fixed prosthodontics at the CHU of Liege for the last 25 years.
- Trial name
- PROCER (NCT07110220)
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Mainjot Amélie
Molar Incisor Hypomineralisation, Enamel Hypomineralization
Comparison of Two Minimally Invasive Approaches for Masking Molar-Incisor Hypomineralization Opacities
This clinical study aimed to compare the effectiveness of two minimally invasive approaches for masking molar-incisor hypomineralization (MIH) opacities and to evaluate esthetic perceptions of children and their parents.
- Conditions
- Molar Incisor Hypomineralisation, Enamel Hypomineralization, Tooth Discoloration
- Trial name
- NCT07494682
- Testing
- Resin infiltration, Etch Bleach Seal Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Molar Incisor Hypomineralization
Effect of Low-intensity Laser and Photodynamic Therapy on Infected Dentin of Permanent Teeth With MIH
The objective of this research was to evaluate the clinical effect of photodynamic therapy on dentin infected by caries lesion in permanent teeth with Molar Incisor Hypomineralization (MIH).
- Trial name
- NCT03826810
- Testing
- aPDT, ART
- Where
- Brazil
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Molar Incisor Hypomineralisation
Molar Incisor Hypomineralisation and Dental Anomalies
Background/study aim: Molar incisor hypomineralisation (MIH) is a common disorder of tooth development. Affected teeth have weak enamel and adult molars often require extensive treatment or even extraction.
- Trial name
- NCT05812690
- Testing
- This is a non intervention - observation only study
- Where
- United Kingdom
- Volunteers
- 1,279 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust