Clinical trials: Tooth Disorder
Children in School
Caries Risk Assessment in Children and Adolescents in the Alpes Maritimes (France)
Identification of caries high risk subjects. Studying the relevance and the distribution of caries risk factors as defined by the HAS, and the part played by the zone of schooling (priority education area or not) Studying the…
- Trial name
- NCT01372436
- Where
- 2 sites in France
- Volunteers
- 678 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Asthma, Dental Caries
Herbal Lollipops on Oral Bacterial Levels and DMFT/Dmft Scores of Children With Asthma Using Inhalers
Young children with asthma who use drugs for their asthma are at higher risk for tooth decay. These drugs can cause (1) dry mouth from less saliva secretion and (2) acid mouth that causes teeth to become soft and bacteria to…
- Trial name
- Lollipops (NCT01147835)
- Testing
- Chinese Licorice Root
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Dental Caries
Evaluation of Preventive Regimens With Different Toothpastes vs Fluoride Varnish & Toothpaste in High Caries Patients
This study will be conducted in order to determine the prevention effect of caries preventive regimen using herbal toothpaste and regimen using fluoride toothpaste versus fluoride toothpaste and fluoride varnish on the caries…
- Trial name
- NCT04436913
- Testing
- Himalaya complete care toothpaste, Signal toothpaste, Signal toothpaste and fluoride varnish
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Cairo University
Congenital Heart Defect, Dental Caries in Children
Oral Health Intervention Program for Children With Congenital Heart Defects
Background: Children with congenital heart defects (CHD) are reported to have poorer oral health compared with healthy children.
- Conditions
- Congenital Heart Defect, Dental Caries in Children, Dental Erosion, Dental Plaque
- Trial name
- NCT03311438
- Testing
- Oral health intervention program
- Volunteers
- 75 people
- Sponsor
- University of Bergen
Dental Pulp Exposure
Comparative Evaluation of Clinical and Radiographic Outcomes of Mustard Gel (Brassica Nigra) and Mineral Trioxide Aggregate (MTA) as Pulpotomy Agents in Deciduous Molars- A Randomized Controlled Trial
The aim of this clinical trial is to compare two materials to treat baby molars with deep cavities. When the cavity is very deep and reaches the nerve of a baby tooth, dentist perform a treatment called "Pulpotomy".
- Trial name
- MG-MTA-RCT2026 (NCT07557290)
- Testing
- Intervention 1: Mustard Gel, Intervention 2 : Mineral Trioxide Aggregate (MTA)
- Volunteers
- 72 people
- Sponsor
- Dr Nida Farooq
Class II Division 1 Malocclusion
Distalization Via Skeletally-anchored Distaljet Appliance With Two Approaches of Micro-osteoperforations
study will be directed to evaluate two approaches of micro-osteoperforations during maxillary molar distalization.
- Trial name
- NCT05171738
- Testing
- skeletally anchored distal jet
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Al-Azhar University
Dental Implant, Tooth Extraction
Soft Tissue Volume Changes After Immediate Implants With Two Different Techniques
The aim is to comparatively evaluate the soft tissue volume changes that occur after tooth extraction and immediate dental implant placement using two different surgical techniques.
- Conditions
- Dental Implant, Tooth Extraction, Bone Resorption
- Trial name
- NCT04803110
- Testing
- Dental implant placement after tooth extraction
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Aula Dental Avanzada
Malocclusion
Three-dimensional Assessment of Craniofacial Structures
The goal of this project is to reduce the radiation exposure in orthodontic patients by the use of a new imaging protocols based on non-ionizing orthodontic records (e.g.
- Trial name
- NCT01210547
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Charcot-Marie-Tooth Disease, Type IA
Assessing Long Term Safety and Tolerability of PXT3003 in Patients With Charcot-Marie-Tooth Disease Type 1A
All randomised patients with Charcot-Marie-Tooth Type 1A (CMT1A) who completed the primary study CLN-PXT3003-02, i.e. treatment with PXT3003 or placebo, are eligible to continue in the extension study CLN-PXT3003-03.
- Trial name
- PLEO-CMT-FU (NCT03023540)
- Testing
- PXT3003
- Where
- 23 sites in United States, Belgium and 5 more
- Volunteers
- 187 people
- Sponsor
- Pharnext S.C.A.
Molar Incisor Hypomineralization
A Comparison of Two Different Management Techniques for Extensive Molar Defects in Patients Suffering From MIH
It is a randomized clinical trial in which two different types of full coverage restoration in used to restore hypomineralized first permanent molar and protect the remaining tooth structure in patients with molar incisor…
- Trial name
- NCT04209920
- Testing
- CAD-CAM milled PMMA crown, Cast metal coping using nickel chromium alloy
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Dental Pulp Disease
Manual and Rotatory Instrumentation Pulpectomy in Primary Mandibular Molars
In this study, the aim is to compare manual and rotatory pulpectomy techniques on 100 primary mandibular molars on children between the ages of 4 and 8 years.
- Trial name
- RotaPulp (NCT04636450)
- Testing
- Rotatory technique pulpectomy, Manual pulpectomy
- Where
- Mexico
- Volunteers
- 100 people
- Sponsor
- Universidad de Guanajuato
Dentin, Carious, Indirect Pulp Capping
Clinical Success of Indirect Pulp Capping: 1-Year Follow-Up
The goal of this clinical trial is to compare the clinical success of theracal pt, therabase, and biodentine indirect pulp capping on primary molars with deep dentin caries.
- Trial name
- NCT06325540
- Testing
- indirect pulp capping with theracal pt, indirect pulp capping with therabase, indirect pulp capping with biodentine
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Dental Caries
Stopping Cavities Study: Diammine Silver Fluoride
This study is being conducted to test whether the use of diammine silver fluoride (also called silver diamine fluoride) hardens the cavity sufficiently so that it arrests.
- Trial name
- NCT02536040
- Testing
- 38% diammine silver fluoride, Water
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Advantage Dental Services, LLC
Oral Health, Oral Hygiene
Effectiveness of Personalized Oral Hygiene Education in Medical and Dental Students Over Two Years
This prospective cohort study is designed to evaluate the long-term effects of individualized oral hygiene education, known as Individually Trained Oral Prophylaxis (iTOP), on oral health outcomes in medical and dental students…
- Conditions
- Oral Health, Oral Hygiene, Periodontal Health, Dental Plaque
- Trial name
- iTOP (NCT07085013)
- Testing
- Individually Trained Oral Prophylaxis (iTOP)
- Where
- Bosnia and Herzegovina
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Mostar
Charcot Marie Tooth Disease
Development of Charcot Marie Tooth Disease (CMT) Pediatric Scale for Children With CMT
The primary goal of this project is to develop and test a Charcot Marie Tooth disease (CMT) Pediatric Scale for use in evaluation in natural history CMT study.
- Trial name
- INC-6603 (NCT01203085)
- Where
- 14 sites in United States, Australia and 3 more
- Volunteers
- 1,201 people
- Sponsor
- University of Iowa
Class II Malocclusion
Evaluation of Maxillary Molar Distalization With Two Bone Supported Protocols Using Cone Beam Computed Tomography
The goal of this clinical trial is to to evaluate and compare the skeletal and dental changes of bone supported Fast Back and bone supported modified Leaf Spring Self-Activated Expander in bilateral distalization of maxillary…
- Trial name
- NCT06308640
- Testing
- Fast Back Rapid Distalizer, Modified Leaf Spring Self-Activated Expander
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tanta University
Tooth, Impacted
A Cluster Randomized Controlled Trial in Primary Oral Care
Background: Routine oral examination (ROE) refers to periodic monitoring of the general and oral health status of patients. In most developed Western countries a decreasing prevalence of oral diseases underpins the need for a…
- Trial name
- NCT00618215
- Testing
- peer group educational implementation strategy
- Where
- Netherlands
- Volunteers
- 1,161 people
- Sponsor
- Radboud University Medical Center
Bruxism, Sleep
Evaluation of the Effectiveness of Infrared LED Photobiomodulation in Children With Sleep Bruxism
Sleep bruxism is a masticatory muscle activity characterized as rhythmic (phasic) or non-rhythmic (tonic). The literature reports the prevalence rates, diverse etiologies and different types of treatment.
- Trial name
- NCT03710174
- Testing
- Infrared LED photobiomodulation, Occlusal splint
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Tooth Discoloration
Tooth Discoloration Induced by Pulpotomy Materials
Vital pulp therapy including pulpotomy is commonly used for managing teeth with carious pulp exposure instead of performing root canal therapy.
- Trial name
- NCT04346849
- Testing
- Pulpotomy
- Where
- 2 sites in Jordan
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Dental Caries
Effectiveness of ART and Conventional Treatment - Practice-based Clinical Trial
Background: Dental caries is still a public health problem among Brazilian children and doubts still exist regarding the most effective restorative technique.
- Trial name
- NCT02568917
- Testing
- Atraumatic Restorative Treatment - Ketac Molar Easy Mix, Conventional Restoration - Composite Resin (Bulk Fill)
- Where
- Brazil
- Volunteers
- 800 people
- Sponsor
- University of Sao Paulo
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