Clinical trials: Tooth Disorder
Clinical Outcome, Endodontic Disease
Clinical Outcomes of Bio-MA and ProRoot MTA in Endodontic Treatment
The purpose of this study is to compare the endodontic outcomes of Bio-MA and ProRoot MTA in pulpotomy, orthograde MTA apical barrier, root perforation repair, endodontic microsurgery.
- Trial name
- NCT04243993
- Testing
- Calcium silicate cement
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Malocclusion, Quality of Life
The Effect of Malocclusions on Oral Health Related Quality of Life
Malocclusions in adolescents may affect oral health related quality of life. The study aims at; 1. Evaluating two instruments measuring oral health related quality of life; "Child Perceptions Questionnaire 11-14" (CPQ 11-14)…
- Conditions
- Malocclusion, Quality of Life, Orthodontics, Adolescent
- Trial name
- NCT05038865
- Testing
- Malocclusion and Orthodontic Treatment
- Where
- 3 sites in Sweden
- Volunteers
- 675 people, healthy volunteers welcome
- Sponsor
- Malmö University
Irreversible Pulpitis (Toothache)
Evaluation Of Laser Versus Conventional Pulpotomies In Mature Molar Teeth With Irreversible Pulpitis
this clinical trial is evaluating the outcome of laser assisted pulpotomy compared to conventional pulpotomy in mature teeth with symptomatic irreversible pulpitis (SIP) assessed by CBCT followed by automated segmentation using…
- Trial name
- NCT07287709
- Testing
- Diode laser, Sodium Hypochlorite Solution
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Rana Hegaz
Caries,Dental
Photobiomodulation on Major Salivary Glands in Children With Caries Activity
The purpose of this trial is to evaluate the efficacy of photobiomodulation of the major salivary glands on salivary parameters in children with caries activity.
- Trial name
- NCT05546528
- Testing
- Photobiomodulation
- Where
- Uruguay
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Molar Incisor Hypomineralization
Accuracy of Spectrophotometry in Hypomineralized Lesions Treated With CPP-ACPF Dental Mousse: Clinical Study
MIH is a condition with considerable prevalence in the child population. This structural defect, represented by a change in the color of the enamel, can be accompanied by structural loss and great sensitivity.
- Trial name
- ASHLTDMCS (NCT06330272)
- Testing
- Application of dental mousse based on CPP-ACPF
- Where
- Brazil
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Meire Coelho Ferreira
Pulp Disease, Dental, Pulp Therapy in Primary Molars
Oxymetazoline Versus Sodium Hypochlorite as Hemostatic Agents in MTA Pulpotomy of Primary Molars
This study aims to evaluate clinical and radiographic success of oxymetazoline versus sodium hypochlorite as hemostatic agents in MTA pulpotomy of primary molars.
- Conditions
- Pulp Disease, Dental, Pulp Therapy in Primary Molars, Pulpitis - Reversible, Pulp Inflammation
- Trial name
- OXY - MTA (NCT07675330)
- Testing
- Oxymetazoline 0.05% nasal solution, Sodium Hypochlorite Solution
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Molar Incisor Hypomineralization
Restoration Quality in Molars Affected by Molar Incisor Hypo Mineralization
Restoration quality of molars affected by MIH using two different types of restorations direct composite and preformed crowns
- Trial name
- NCT04475419
- Testing
- preformed stainless steel crowns cemented by glass ionomer luting cement(Ketac Cem, 3M Espe)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Effect of Silver Diamine Fluoride and LED Activation on Residual Caries Activity in Class II Cavities
This observational clinical study investigates the effect of silver diamine fluoride (SDF) and its activation with light-emitting diode (LED) on residual caries activity after caries excavation in Class II primary molar cavities.
- Trial name
- NCT07250009
- Testing
- DIAGNOdent measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Class II Malocclusion
Maxillary Segmental Distalization Using Digitally Printed Appliances
Evaluation of Maxillary Segmental Distalization Using Infrazygomatic versus Palatal Digitally Printed Skeletal Anchored Appliances.
- Trial name
- NCT06511219
- Testing
- maxillary segmental distalization
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Dental Caries
Use of Antibacterial Cement in Infected Dentin
Dental materials with antibacterial properties can prevent the harmful effects caused by oral cariogenic bacteria. This double-blind controlled clinical trial evaluated the performance of antibacterial cement for sealing infected…
- Trial name
- AC (NCT01449136)
- Testing
- Antibacterial cement
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- University of Pernambuco
Oral Health
Cluster RCT on the Effect of the Topics Number in Oral Health Educational Video Among Preschool Children.
Purpose: This cluster randomized controlled trials study aims to investigate whether different number of topics delivered through educational video affect the oral health status, knowledge, attitude and practice of preschool…
- Trial name
- NCT06073392
- Testing
- Educational video
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Dental Diseases
Parental Attitude Toward Children Dental Treatment During COVID-19 Pandemic
The aim of this study is assessment of parental attitude toward children dental treatment and care during Covid 19- crisis
- Trial name
- NCT04512300
- Where
- Egypt
- Volunteers
- 267 people
- Sponsor
- Cairo University
Dental Caries
Cost-efficacy of Sealing Moderate Caries Lesions in Occlusal Surfaces of Primary Molars
This protocol aims to assess the cost-efficacy and applicability of the treatment of lesions moderate caries using sealants as an alternative to the restorations on occlusal surfaces of deciduous teeth.
- Trial name
- NCT03005405
- Testing
- Ionomer Restoration (control), Ionomer Sealant (test), Oral hygiene orientation and professional fluoride application
- Where
- Brazil
- Volunteers
- 96 people
- Sponsor
- University of Sao Paulo
Malocclusion
OrthoPulse™ and Its Effect on the Rate of Orthodontic Tooth Alignment: A Pilot Feasibility Study
The aim of this study is to determine the effect of OrthoPulse™, an intra-oral LED (Light Emitting Diode) photobiomodulation device, on the rate of anterior orthodontic alignment.
- Trial name
- NCT02267837
- Testing
- OrthoPulse™
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Biolux Research Holdings, Inc.
Molar Incisor Hypomineralisation
SleeperOne® 5 Intraosseous Anesthesia in MIH
This randomized split-mouth clinical trial evaluates whether computer-controlled intraosseous anesthesia delivered with the SleeperOne® 5 system reduces pain perception and dental anxiety compared with conventional local…
- Trial name
- CCLAD-MIH (NCT07741487)
- Testing
- SleeperOne® 5 Computer-Controlled Intraosseous Anesthesia, Conventional Local Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Ankara University
Immature Teeth, Necrotic Pulp
Efficacy of Integrated Nano-technology in Revascularization of Immature Necrotic Teeth
This trial aims to study the effect of photoactivated disinfection using Diod laser (810 nm) to activate photosensitive nanoparticle chitosan as an endodontic irrigant versus sodium hypochlorite followed by saline and then EDTA…
- Trial name
- NCT06631885
- Testing
- regenerative endodontic procedure using blood clot according to AAE, regenerative endodontic procedure using photo activated nanochitosan 2%
- Volunteers
- 20 people
- Sponsor
- Minia University
Dental Caries in Children
The Impact of Anticipatory Guidance on Early Childhood Caries: a Quasi-experimental Study
This study aimed to compare the impact of anticipatory guidance on the caries incidence of 2-3-year-old preschool children and their 4-6-year-old siblings, as well as on their mothers' oral health literacy, as compared to the…
- Trial name
- NCT03478748
- Testing
- Dental health education
- Where
- Malaysia
- Volunteers
- 478 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Cavities of Teeth
An Evaluation of Protective Effects of OpalSeal™ Against Early Dental Decay in Orthodontic Patients
Fluoride is very effective in preventing dental decay (cavities) when applied in the form of a varnish on tooth surfaces. The purpose of this study is to verify if fluoride-releasing primer (OpalSeal) offers more protection…
- Trial name
- NCT03722264
- Testing
- OpalSeal, TransbondXT
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Virginia Commonwealth University
Charcot-Marie-Tooth Disease With Sorbitol Dehydrogenase Deficiency (CMT-SORD)
Confirmatory Study of Govorestat in CMT-SORD
This study is designed to assess the long-term efficacy and clinical benefit of AT-007 in patients with CMT-SORD. This randomized, double-blind study will assess the effect of govorestat compared to placebo in patients with…
- Trial name
- NCT07191912
- Testing
- Govorestat
- Where
- 13 sites in United States, Australia and 5 more
- Sponsor
- Applied Therapeutics, Inc.
Caries,Dental, Crown of Tooth With Poor Contour
Clinical and Radiographical Evaluation of CAD-CAM Crowns With and Without Deep Margin Elevation
Deep margin elevation (DME) is a non-invasive restorative technique to relocate the deep cervical margin to a supragingival position using resin composite.
- Conditions
- Caries,Dental, Crown of Tooth With Poor Contour, Broken Teeth, Survival, Prosthesis
- Trial name
- NCT06114030
- Testing
- Deep margin elevation with composite resin and Lithium disilicate glass-ceramic crowns
- Where
- United Arab Emirates
- Volunteers
- 560 people
- Sponsor
- University of Sharjah
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