Clinical trials: Tooth Disorder
Class II Division 1 Malocclusion, Retrognathic Mandible
Fixed Lingual Mandibular Growth Modificator
The current trial was designed to investigate the possible initial net skeletal and dental effects of treatment with FLMGM by a comparative evaluation of treated and untreated Cl II/1 malocclusion subjects.
- Trial name
- FLMGM (NCT01853137)
- Testing
- Fixed Lingual Mandibular Growth Modificator (FLMGM)
- Where
- Syria
- Volunteers
- 43 people
- Sponsor
- Damascus University
Crowding, Tooth, Gingival Diseases
Gingival Phenotype and Dental Crowding in Pediatric Patients
The periodontal phenotype influences treatment outcomes across dental specialties, as tissues of different thickness respond differently to chemical, bacterial, and mechanical insults.
- Trial name
- BIOTIPO_PEDO (NCT07205172)
- Testing
- Orthodontic and periodontal analysis
- Where
- Italy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Early Childhood Caries, Dental Caries in Children
Treatment of Early Childhood Caries Using Silver Diammine Fluoride and Sodium Fluoride Tricalciumphosphate and the Effects on Oral Health Related Quality of Life
There is still a need for the assessment of different minimal intervention strategies and treatments focusing on the prevention and arrest of carious lesions of primary molars The evidence-based clinical practice guideline on…
- Conditions
- Early Childhood Caries, Dental Caries in Children, Dental Caries Extending Into Dentin, Dental Caries
- Trial name
- NCT05772039
- Testing
- Topical application of 38% Silver Diammine Fluoride Solution, Topical application of 5% Sodium Fluoride with functional Tricalcium phosphate Varnish
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- Universiti Sains Malaysia
Pain, Postoperative, Dental Pain
A Study of Acetaminophen for Post Surgical Dental Pain
To assess the safety, tolerability, analgesic, efficacy and pharmacokinetics of high dose acetaminophen relative to placebo and low dose acetaminophen relative to placebo over a 24 hour period in patient experiencing moderate to…
- Trial name
- NCT04018612
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Nevakar, Inc.
Dental Caries
Occlusal Compensation After the Hall Technique
The Hall Technique preformed metal crown (HTPMC) is used to treat decayed primary molars. The correct size is chosen and pushed over the tooth with no tissue removal.
- Trial name
- CHAT (NCT04001153)
- Testing
- Dental impressions
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Dundee
Tooth Diseases, Caries,Dental
Dental Practitioners KAP Regarding Caries Preventive Measures in Cairo and Riyadah
The study aims to evaluate the knowledge, attitude, and practice of dental practitioners from Cairo and Riyadh regarding caries preventive measures.
- Trial name
- NCT05792800
- Where
- Egypt
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Building Adaptive School-based Interventions for Caries
Dental caries (tooth decay) is the world's most prevalent noncommunicable disease. Current preventive and therapeutic treatments are available that can be provided in a school-based health service environment.
- Trial name
- BASICS (NCT07265830)
- Testing
- Silver Diamine Fluoride (38%), Glass Ionomer Sealant, Fluoride Varnishes
- Where
- United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Dental Caries, Infectious Diseases
Bifidobacterium Lactis BB12 and Xylitol Delivered With a Novel Slow-release Pacifier
Aims: 1. To develop a food supplement containing a health-promoting probiotic bacteria (B. lactis BB12) and xylitol to be administered with a novel soft, possibly occlusion-friendly pacifier. 2.
- Trial name
- NCT00638677
- Testing
- Sorbitol, Xylitol + BB12, Xylitol
- Where
- Finland
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Turku
Dental Caries
Effectiveness of Oral Health Education Programs Among School Children, Their Mothers and Teachers in Fayyum: Cohort Study
Cohort study to evaluate the effect of oral health educational program effect on oral health of school children, their mothers and teachers
- Trial name
- NCT05980273
- Testing
- Educational sessions
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Reliability of Fluorescent Camera and Caries Detection Dye Versus the Visual Tactile Method
1. Three dentinal carious lesions will be chosen in this study and will be in the same patient. 2. Using local anaesthesia and rubber dam, the operative field will disinfected with 1% hypochlorite, and the dentine lesions should…
- Trial name
- NCT03051594
- Testing
- fluorescent camera, caries detector dye, visual tactile assessment
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries, Fissure Sealant
The Effect of an Adhesive System on the Retention and Caries Prevention for Fissure Sealants in Permanent Molars
Background: Resin-based fissure sealants (FS) are recommended to prevent pit-and-fissure caries development or prevent the progression of enamel caries lesion to frank cavitation into dentine.
- Trial name
- ResinFS (NCT06608563)
- Testing
- Fissure sealant without adhesive system (NO BOND), Fissure sealant with adhesive system (BOND)
- Where
- Ireland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Dublin, Trinity College
Tooth Migration
The Effects of Different Activation Protocols of Hycon Device and Vibration Stimulation on Canine Teeth Distalization
This study will be performed with 25 patients who applied to Erciyes University Faculty of Dentistry for treatment and who need 2 first premolar extraction and maximum anchorage for treatment.
- Trial name
- Acceleration (NCT03968263)
- Testing
- Hycon device(Routine protocol), Hycon device(Modified protocol), Hycon device(Routine protocol) and Vibration(Acceledent)
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
CLASS II DIVISION 1 MALOCCLUSION, Class II Malocclusion
The Effectiveness of the Twin Block and Carriere Motion Appliances in Post-pubertal Patients and an Evaluation of the Impact of Class II Malocclusion and Its Correction on Oral Health-related Quality of Life
The investigators of this clinical trial aim to: Compare the effectiveness and efficiency of Clark's Twin Block Appliance (CTB) vs Carriere Motion Appliance (CMA) in correcting Class II malocclusion when used in post-pubertal…
- Conditions
- CLASS II DIVISION 1 MALOCCLUSION, Class II Malocclusion, Growth, Overjet
- Trial name
- NCT07292636
- Testing
- CTB, CMA
- Where
- Ireland
- Volunteers
- 88 people
- Sponsor
- Aslam Alkadhimi
Dental Caries, Gingivitis
Parental Perception of Oral Health-Related Quality of Life in Sudanese Refugee vs. Egyptian Children
This cross-sectional analytical study aims to assess and compare parental perceptions of oral health-related quality of life (OHRQoL) among Sudanese refugee children and Egyptian children aged 6-12 years living in Egypt.
- Conditions
- Dental Caries, Gingivitis, Oral Health, Refugee Health
- Trial name
- NCT07011381
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Supernumerary Teeth
Prevalence of Erupted Supernumerary Teeth Among a Group of Egyptian Children Aged From Six to Fifteen Years Old
The purpose of this study is to assess the prevalence of erupted supernumerary teeth among a group of Egyptian children aged from 6-15 years old attending the Outpatients' clinic of Pediatric Dentistry and Dental Public Health…
- Trial name
- NCT03650634
- Where
- Egypt
- Volunteers
- 604 people, healthy volunteers welcome
- Sponsor
- Cairo University
Sensitivity, Tooth
Evaluation of Gluma Desensitizer in Post-treatment Sensitivity in Posterior Composite
To evaluate the effect of Gluma desensitizer in controlling immediate post-treatment sensitivity in posterior occlusal composite restorations.
- Trial name
- NCT04248803
- Testing
- GLUMA (Kulzer GmbH, Germany) desensitizing agent
- Where
- India
- Volunteers
- 570 people, healthy volunteers welcome
- Sponsor
- Tamil Nadu Dr.M.G.R.Medical University
Dentin Sensitivity
Use of Biomaterials as Desensitizer Agents
Aim: to investigate the clinical effectiveness over 12 weeks of three different biomaterials, nano-hydroxyapatite based, in the therapy of the dental sensitivity.
- Trial name
- NCT02770573
- Testing
- Cavex Bite&White ExSense, Kuraray Teethmate™ Desensitizer, Ghimas Dentin Desensitizer
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Università degli Studi di Sassari
Evaluations, Diagnostic Self, Antimicrobial
ZnO Nanoparticles Coated Orthodontic Molar Tube
Orthodontic treatment is an elective procedure to improve the patient's dentofacial appearance. The complex design of fixed appliances provides a platform that leads to increased plaque accumulation around orthodontic brackets.
- Conditions
- Evaluations, Diagnostic Self, Antimicrobial, Orthodontic Appliance Complication, Bacterial Overgrowth
- Trial name
- ZnONPs (NCT06089720)
- Testing
- Zinc oxide nanoparticle coated orthodontic molar tubes (experimental), orthodontic molar tubes (control)
- Where
- Iraq
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Dental Caries in Children, Dental Caries Class II
Treatment of Interproximal Cavities on Primary Molar Teeth With Silver Diamine Fluoride
This study investigates whether 1) Silver diamine fluoride (SDF) application using Super Floss can arrest and/or reverse initial interproximal caries on primary molars and 2) whether SDF applied with Super Floss is more effective…
- Conditions
- Dental Caries in Children, Dental Caries Class II, Dental Caries
- Trial name
- NCT03770286
- Testing
- 5% Fluoride Varnish, 38% Silver diamine fluoride, Super Floss
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Dental Plaque Accumulation
Effectiveness of Ortho-Buddy on Plaque Control in Orthodontic Patients
The goal of this clinical trial is to learn whether the Ortho-Buddy toothbrush can improve plaque removal in adolescents undergoing orthodontic treatment with fixed appliances.
- Trial name
- NCT07810868
- Testing
- Standard Toothbrush, Ortho-Buddy
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Rutgers, The State University of New Jersey
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