Clinical trials: Tooth Disorder
Endodontically Treated Teeth
Apical Gap Length and Adaptation of Zirconia Post Using Intraoral and Extraoral Scan of Silicon Impression Technique
First, participants will undergo clinical and radiographic examination for taking all the needed preoperative records, then endodontically treated teeth preparation starting with removal of any carious or undermined tooth…
- Trial name
- NCT05476419
- Testing
- Direct intra-oral scanning technique for the post space.
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
A Study to Evaluate the Cariostatic Efficacy of Nano Silver Fluoride (NSF) vs. Silver Diamine Fluoride (SDF) in Children
This study, titled "A Randomized Controlled Trial to Evaluate the Cariostatic Efficacy of Nano Silver Fluoride (NSF) vs. Silver Diamine Fluoride (SDF) in Children" (Study Number: ATSU-YI-NSF 2025), is sponsored by Young…
- Trial name
- NCT07861321
- Testing
- Nano Silver Fluoride / NSF
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- A.T. Still University of Health Sciences
Dental Caries, Primary Teeth
Discomfort Evaluation During Atraumatic Restorative Treatment in Children
This study evaluates the patient 's discomfort when submitted to partial caries removal through the atraumatic restorative treatment compared to chemo-mechanical caries removal using Papacarie™ gel.
- Conditions
- Dental Caries, Primary Teeth, Post Dental Restoration
- Trial name
- NCT03143387
- Testing
- Caries removal using only manual instruments, Caries removal using Papacarie gel
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Faculty Sao Leopoldo Mandic Campinas
Malocclusion
Maximum Clinical Insertion Torque and Its Association With the Success Rate of Orthodontic Miniscrews
Orthodontic miniscrews provide temporary skeletal anchorage but are lost prematurely in a proportion of cases despite correct placement.
- Trial name
- MTtorque (NCT07780149)
- Testing
- microscrew
- Where
- Chile
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Charcot Marie Tooth Disease (CMT), Neuromuscular Diseases (NMD)
Treatment of Charcot-Marie-Tooth Disease, Axonal, Type 2S (CMT2S) in an Individual Patient
This is an 'N of 1', open-label, single center study to evaluate the safety of therapy with VCA-894A, an ASO designed to rescue and restore the activity of IGHMBP2, when administered by intrathecal injection.
- Trial name
- NCT07223632
- Testing
- VCA-894A
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Vanda Pharmaceuticals
Malocclusion, Angle Class II
Therapeutic Effects of Class II Elastics on Aligners in Different Vertical Skeletal Patterns
The objective is to compare the dento-alveolar therapeutic effects of wearing class II inter-arch traction elastics on aligners versus multi-brackets in an adult population.
- Trial name
- NCT05853211
- Testing
- Aligner and inter-arch elastics
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Dental Caries
Three Measures for the Prevention of Carious Lesions in Preschool Children
Analysis different measures preventive effect on carious Lesions incidence and oral microecological system change of preschool children
- Trial name
- NCT02341352
- Testing
- fluoride varnish, Immunoglobulin Yolk, Probiotics
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
Bruxism, Sleep
Pain and Mobility in Children With Sleep Bruxism
Bruxism is defined as a repetitive jaw muscle activity characterized by clenching and grinding teeth caused by mandibular movement. Sleep bruxism is frequently seen and can affect the quality of life of individuals.
- Trial name
- NCT06937333
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Charcot-Marie-Tooth Disease, Healthy
Charcot-Marie-Tooth Disease (CMT) Biological Sample Collection for IPSC Generation and Biobanking
The New York Stem Cell Foundation (NYSCF) Research Institute is performing this research to accelerate Charcot-Marie-Tooth disease research and drug development by using cells from the body (such as skin or blood cells) to make…
- Trial name
- NCT06203093
- Testing
- Biological Sample Collection
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- New York Stem Cell Foundation Research Institute
Amelogenesis Imperfecta
Amelogenesis Imperfecta
Amelogenesis Imperfecta (AI) are a heterogeneous group of rare genetic diseases transmitted according to various mode of inheritance (X-linked, autosomal dominant, autosomal recessive) affecting the formation/mineralization of…
- Trial name
- NCT01746121
- Testing
- Salivary and blood sampling, as part of routine care. Collection of exfoliated teeth.
- Where
- France
- Volunteers
- 600 people
- Sponsor
- University Hospital, Strasbourg, France
Dental Caries
Injectable Bioactive Composites vs RMGI for Proximal Cavities in Primary Molars
This randomized clinical trial aims to evaluate and compare the clinical performance of injectable bioactive composite (Beautifil Flow Plus X, Shofu) versus Resin Modified Glass Ionomer (RMGI) in restoring proximal cavities…
- Trial name
- GIOMER-RCT (NCT07561216)
- Testing
- giomer, RMGI
- Volunteers
- 50 people
- Sponsor
- Cairo University
Class II Malocclusion
Evaluation of the Levels of Pain, Discomfort, and Functional Impairment With Two Techniques of Retraction
Thirty-eight patients requiring extraction of maxillary first premolars will participate in the study. They will be divided randomly into two groups: an en-masse retraction group and a two-step group.
- Trial name
- NCT05652244
- Testing
- Mini-implants, Transpalatal arche (TPA)
- Where
- Syria
- Volunteers
- 38 people
- Sponsor
- Damascus University
Bruxism
Management of Myofascial Pain in Children With Sleep Bruxism
This study compared the effectiveness of Kinesio tape and occlusal splint application in improving sleep quality and reducing myofascial pain in children with sleep bruxism.
- Trial name
- NCT06232993
- Testing
- Kinesio taping, Occlusal Splinting, Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Adiyaman University
Tooth Eruption, Atherosclerosis
P Gingivalis Oral Infection, Intimamedia Thickening in Infants, Atherosclerosis
To determine if there is an association between Porphyromonas gingivalis infection of dental gingiva during primary tooth eruption and thickening of the radial artery intimamedial layers.
- Trial name
- NCT03083444
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Creighton University
Lead Poisoning, Obesity
QI Study of a Practice Facilitator's Impact in Working With Clinics on Improving Dental, Lead & Obesity Measures for Children
Funded by the Ohio Department of Job and Family Services - Medicaid Technical Assistance and Policy Program (MEDTAPP), the "Child Health Excellence Center - a University-Practice-Public Partnership" (CHEC-UPPP) focuses on…
- Conditions
- Lead Poisoning, Obesity, Dental Decay
- Trial name
- NCT01739166
- Testing
- Practice-tailored intervention to increase rates of targeted services
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Dental Caries
Evaluation of a Brief Tailored Motivational Intervention to Prevent Early Childhood Caries
The Detroit Dental Health Project (DDHP)aims to promote oral health and reduce disparities within the community of low-income African-American children (0-5 years) and their main caregivers (14+ years), living in the City of…
- Trial name
- NCT01123330
- Testing
- Motivational Interviewing
- Where
- United States
- Volunteers
- 2,042 people, healthy volunteers welcome
- Sponsor
- Temple University
Dental Plaque, Gingivitis
Effectiveness of Toothbrushing Habits of Preschool Children, With or Without a Toothbrushing Assisting Application
The aim of this study is to investigate the effectiveness of the use of a toothbrushing assisting mobile application in dental plaque removal and adherence to the toothbrushing routine, in preschool children (3-5 yrs old) when…
- Trial name
- NCT05788692
- Testing
- electric tootbrush, manual toothbrush, toothbrushing assisting application
- Where
- 6 sites in Greece
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Dental Caries, Glass-Ionomer Cement
Heated Glass Ionomer Cement in Primary Molars
Objective: The aim of this study was to assess the influence of heated in the clinical success of proximal high viscosity glass ionomer cement (GIC) restorations in primary molars.
- Conditions
- Dental Caries, Glass-Ionomer Cement, Primary Teeth
- Trial name
- NCT04291872
- Testing
- Glass -Ionomer Cement with /without Led Light Cure
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Marmara University
Early Childhood Caries, Dental Caries in Children
Treatment of Early Childhood Caries Using Silver Diammine Fluoride and Sodium Fluoride Tricalciumphosphate and the Effects on Oral Health Related Quality of Life
There is still a need for the assessment of different minimal intervention strategies and treatments focusing on the prevention and arrest of carious lesions of primary molars The evidence-based clinical practice guideline on…
- Conditions
- Early Childhood Caries, Dental Caries in Children, Dental Caries Extending Into Dentin, Dental Caries
- Trial name
- NCT05772039
- Testing
- Topical application of 38% Silver Diammine Fluoride Solution, Topical application of 5% Sodium Fluoride with functional Tricalcium phosphate Varnish
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- Universiti Sains Malaysia
Endodontically Treated Teeth
Influence of Working Length Methods in the Performance of Pulpectomies in Primary Teeth
Verify, through a randomized double-blinded clinical trial, the influence in the performance of pulpectomies in primary teeth, based on two working length methods, electronic and radiographic.
- Trial name
- NCT03161639
- Testing
- Pulpectomies
- Where
- 2 sites in Brazil
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Santa Catarina
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