Clinical trials: Tooth Disorder
Malocclusion, Orthodontics
Occlusal Outcomes by OGS After a Finishing Protocol
Evaluation of the effects of the implementation of a new finishing protocol in orthodontics patients
- Trial name
- NCT03714087
- Testing
- T1 before aligner, T2 after the aligner, Historic control group
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Dental Plaque (Diagnosis), Deep Learning
Microbial Dental Plaque Analysis in Young Permanent Teeth Using Deep Learning
Background: Dental plaque contributes to a number of common oral conditions such as caries, gingivitis, and periodontitis. As a result, detection and management of plaque is of great importance for the oral health of individuals.
- Trial name
- NCT06603233
- Testing
- The Difference Between The AI Model and Dentists Group, Deep Learning Models
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Ankara Medipol University
Root Caries
Egyptian Dentists Knowledge Regarding the Diagnosis and Management of Root Caries
This is a cross-sectional study that aims to assess the knowledge of a sample of Egyptian dental practitioners regarding the diagnosis and management of root caries Dental caries is a major problem for adults in both developing…
- Trial name
- NCT06619652
- Where
- Egypt
- Volunteers
- 355 people
- Sponsor
- Cairo University
Demineralization, Tooth, Caries,Dental
Prospective Randomized Controlled Trial for Prevention of Demineralization During Fixed Orthodontic Treatment
Treatment with fixed orthodontic appliances is often associated with pain, which poses great challenges in the efficient brushing of the teeth thus making the teeth more vulnerable to plaque formation.
- Conditions
- Demineralization, Tooth, Caries,Dental, White Spot Lesion
- Trial name
- NCT04342858
- Testing
- Fluoride Varnish, Fluoride Varnish with tricalcium phosphate, Oral health education
- Where
- Hong Kong
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Gingival Hyperplasia, Dental Plaque
Clinical Efficacy of Chlorhexidine Varnish in Reducing Gingival Hyperplasia, Plaque Accumulation, and White Spot Lesions in Orthodontic Patients
This study investigates whether applying a chlorohexidine varnish (a dental coating) reduces gum overgrowth, plaque buildup, and early tooth decay (white spots) in patients with braces.
- Conditions
- Gingival Hyperplasia, Dental Plaque, Tooth Demineralization
- Trial name
- NCT07115784
- Testing
- Chlorhexidine Varnish
- Where
- Pakistan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Molar Incisor Hypomineralization
Clinical Performance of Two Cad-cam Fabricated Ceramic Restoration in Teeth Affected With MIH
This study will be performed to evaluate the clinical performance (Plaque accumulation, fracture of (restoration or tooth), postoperative sensitivity, secondary caries, marginal fit and discoloration) of two CAD/CAM fabricated…
- Trial name
- NCT05434884
- Testing
- occlusal veneer restorations, endocrown restorations
- Where
- Egypt
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Deep Caries, Molar Incisor Hypomineralisation
Comparison of Intraosseous Anaesthesia Using a Computerized System (QuickSleeper) to Conventional Anesthesia
The purpose is to compare the efficacy of an intraosseous anaesthesia using a computerized system (QuickSleeper) to a conventional infiltration anesthesia.
- Trial name
- QUICK (NCT02084433)
- Testing
- intraosseous anaesthesia using a computerized system, conventional anasthesia
- Where
- France
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Dental Caries, Early Caries Lesions
A Randomized Split-Mouth Clinical Trial Comparing Resin Infiltration and Microabrasion for Early Caries Lesions
This study aims to evaluate and compare the clinical characteristics and treatment outcomes of early caries lesions using resin infiltration (Icon) and microabrasion (Opalustre).
- Conditions
- Dental Caries, Early Caries Lesions, White Spot Lesions[Initial Caries]on Smooth Surface of Tooth
- Trial name
- ICON-CTU (NCT07544849)
- Testing
- Resin Infiltration, Microabrasion
- Where
- Vietnam
- Volunteers
- 30 people
- Sponsor
- Can Tho University of Medicine and Pharmacy
Molar Incisor Hypomineralization, Hypersensitivity
The Desensitising Effect of Nanosilver Fluoride in Molar-Incisor Hypomineralisation
The aim of the current study is to assess the desensitising effect of nanosilver fluoride on first permanent molars (FPMs) in patients with MIH in comparison to low-level laser therapy.
- Trial name
- NCT06348849
- Testing
- Low-level laser therapy, Nanosilver fluoride
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Alexandria University
Dental Pulp Necroses
Efficacy of Regenerative Endodontic Treatment With PRF as a Secondary Treatment of Mature Necrotic Incisors in Adolescents
Evalaution of clinical success of secondary treatment for total 40 permanent incisors with failed root canal treatment with apical radiolucency.
- Trial name
- PRF (NCT05517187)
- Testing
- no intervention, Platelet rich fibrin
- Where
- 2 sites in Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nahda University
Caries, Dental, Caries; Dentin
3D-printed Ceromer Crowns Versus Stainless Steel in Posterior Primary Molars
The aim of the study is to compare preformed metal crowns and 3D-printed ceromer crowns in primary molars of 4-9 years old children.
- Conditions
- Caries, Dental, Caries; Dentin, Dental Caries in Children
- Trial name
- NCT07091331
- Testing
- Personalized 3D-printed pediatric ceromer crown, Prefabricated stainless steel crown group
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Universidad Autonoma de Baja California
Endodontic Disease
Evaluation of Antimicrobial Efficacy and Adaptability of Bioceramic Sealer Containing Nanoparticles
Successful endodontic treatment depends primarily on the elimination of infecting microorganisms. This is done by chemo-mechanical preparation of root canals, which is not enough and microorganisms might still survive.
- Trial name
- NCT04481945
- Testing
- bioceramic sealer
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Misr International University
Plaque Accumulation
Water Flossing Versus Dental Floss for Oral Hygiene in Children Aged 10-15 Years: A Randomized Trial
The goal of this Randomized Clinical Trial is to compare the effectiveness of water flossing versus regular flossing in reducing dental plaque in children aged 10-15 years.
- Trial name
- NCT07469839
- Testing
- Unflavored, unwaxed regular dental floss (Oral-B, USA), Water flosser (Waterpik Cordless Plus Water Flosser, USA)
- Where
- Saudi Arabia
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Maxillary Hypoplasia, Malocclusion, Angle Class III
Effect of Bone-anchored Protraction on Maxillary Growth in the Young Child
Class III malocclusions may originate in a retrognathic maxilla, a prognathic mandible or both. Young patients with class III malocclusion and maxillary hypoplasia are conventionally treated with a protraction facemask in order…
- Trial name
- NCT02711111
- Testing
- Face mask, orthodontic bone anchor
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ziekenhuis Oost-Limburg
Caries
Is DIAGNOcam Comparable to Bitewing Radiographs as a Diagnostic Method for Approximal Caries in Primary Teeth?
BACKGROUND: To diagnose caries in clinical practice today, a combination of clinical examination with mirror and probe, and in sometimes x-ray images are used.
- Trial name
- Diagncamera (NCT03181711)
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Malmö University
Tooth Decay
Efficacy Trial of MySmileBuddy
This study seeks to evaluate the best way to encourage a healthy diet and proper fluoride use in children at greatest risk for tooth decay.
- Trial name
- NCT04845594
- Testing
- MySmileBuddy (MSB)
- Sponsor
- Columbia University
Dental Fluorosis
Clinical Severity of Dental Fluorosis and Associated Risk Factors Among a Group of Children in Rural Region, Dendera Center in Egypt
The goal of our observational study is evaluation of the clinical severity of dental fluorosis and associated risk factors among a group of children (8-12 years old) in a rural region, Dendera center, Egypt.
- Trial name
- NCT07138456
- Where
- Egypt
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries, Dental Plaque
Comparative Effectiveness of Various Educational Approaches on Oral Hygiene
Background: Dental caries constitutes a major global public health challenge, posing substantial burdens on both oral health outcomes and healthcare systems worldwide, with far-reaching implications for prevention, treatment, and…
- Trial name
- NCT06910501
- Testing
- Traditional oral hygiene instruction, Digital slide-based education, Brush DJ mobile appliaction
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ege University
Pulpitis, Pulp Disease, Dental
Bioactive Materials in Pulp Therapy of Primary Teeth
The purpose of this study is to compare the clinical and radiographic success of a new injectable, fast setting bioceramic root repair material (BC RRM) putty with mineral trioxide aggregate (MTA) in pulpotomy procedures of…
- Trial name
- NCT04795830
- Testing
- Bioceramic root repair material as pulp dressing in pulpotomy in primary molars, Mineral Trioxide Aggregate as pulp dressing in primary molars (MTA)
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Malaria
Impact of Malaria Mass Drug Administration on Malaria Prevalence in Under 15 Children and Pregnant Women
This is a clinical trial being done to find better ways to reduce malaria in the community. Malaria is caused by a parasite that is spread by mosquitoes.
- Trial name
- NCT07358767
- Testing
- Artemether-lumefantrine (AL)
- Where
- Ghana
- Volunteers
- 3,300 people, healthy volunteers welcome
- Sponsor
- Noguchi Memorial Institute for Medical Research
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