Clinical trials: Tooth Disorder
Hypersensitivity Dentin
Potassium Nitrate Gel and Diode Laser for Dentinal Hypersensitivity
The goal of this randomized clinical trial is to evaluate whether combining a potassium nitrate gel with diode laser therapy is more effective in treating dentinal hypersensitivity compared to using the gel alone.
- Trial name
- NCT06746558
- Testing
- Potassium Nitrate Gel and Diode Laser Therapy, Potassium Nitrate Gel Alone
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- University of Modena and Reggio Emilia
Dental Caries, Primary Molars
Clinical Performance of Four Restorative Materials in Primary Molars
This randomized clinical trial aims to compare the clinical and radiographic performance of four direct restorative materials used for restoring carious primary molars in children.
- Trial name
- NCT07504393
- Testing
- Cention N, Stela, SDI, Australia, Beautifil II, Shofu, Japan
- Volunteers
- 92 people
- Sponsor
- Al-Azhar University
Plaque, Dental, Caries, Dental
Livionex on Reducing Plaque Accumulation and Improving Oral Health in Children
This is an investigator initiated randomized double-blind pilot study at the UCSF Pediatric Dental Clinics to compare effectiveness of a new toothpaste Livionex Dental Gel with a standard children's toothpaste containing 1500 ppm…
- Conditions
- Plaque, Dental, Caries, Dental, Oral Hygiene
- Trial name
- NCT04368533
- Testing
- Livionex Dental Gel, A standard children's toothpaste containing 1500 ppm fluoride
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Dental Plaque, Gingivitis
Mechanical Plaque Control and Gingivitis Reduction in Fixed Appliance Patients
The purpose of this study is to determine whether the use of a sonic toothbrush alone is more effective than two other toothbrushing protocols on dental plaque elimination in patients with fixed orthodontic appliances.
- Trial name
- NCT00681135
- Testing
- sonic toothbrush (Philips Sonicare® FlexCare, Typ HX6942/04), manual toothbrush / interdental toothbrush (elmex® Inter X medium toothbrush / interdental brush Curaprox®), manual toothbrush (elmex® Inter X medium toothbrush)
- Where
- Germany
- Volunteers
- 118 people
- Sponsor
- Sebastian Zingler
Malocclusion, Angle Class II, Division 1
Evaluation of Mini Plates Anchorage With Forsus Fatigue Resistant Device
The purpose of this study is to determine if the Forsus Fatigue resistant Device appliance with direct skeletal mini plates anchorage is capable of achievement of skeletal mandibular effects while preventing the excessive…
- Trial name
- NCT02475785
- Testing
- FFRD and mini plates group, Conventional FFRD
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Sherif A. Elkordy
Patient Satisfaction
DPBRN Patient Satisfaction With Dental Restorations
The purpose of this study was to administer two questionnaires. The first, a Dental Satisfaction Questionnaire to assess patient satisfaction with a restoration visit using patients recruited from practices participating in the…
- Trial name
- NCT01201421
- Where
- 7 sites in United States, Denmark
- Volunteers
- 5,932 people, healthy volunteers welcome
- Sponsor
- Dental Practice-Based Research Network
Dental Caries
A Study to Evaluate the Cariostatic Efficacy of Nano Silver Fluoride (NSF) vs. Silver Diamine Fluoride (SDF) in Children
This study, titled "A Randomized Controlled Trial to Evaluate the Cariostatic Efficacy of Nano Silver Fluoride (NSF) vs. Silver Diamine Fluoride (SDF) in Children" (Study Number: ATSU-YI-NSF 2025), is sponsored by Young…
- Trial name
- NCT07861321
- Testing
- Nano Silver Fluoride / NSF
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- A.T. Still University of Health Sciences
Dental Plaque
Efficacy of Plaque Removal of a Novel Brushing Device
The purpose of this research study is to compare how a novel, automated mouthpiece-based toothbrushing device removes dental plaque compared to a manual toothbrush.
- Trial name
- NCT05038293
- Testing
- Automated mouthpiece-based toothbrush, Manual toothbrush
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Washington
Charcot-Marie-Tooth Disease, Type Ia (Disorder), HMSN
Genetics of Charcot Marie Tooth (CMT) - Modifiers of CMT1A, New Causes of CMT2
This project includes two projects. One is looking for new genes that cause Charcot Marie Tooth disease (CMT). The other is looking for genes that do not cause CMT, but may modify the symptoms a person has.
- Trial name
- INC-6602 (NCT01193088)
- Where
- 24 sites in United States, Australia and 4 more
- Volunteers
- 1,050 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Malocclusion
Early Orthodontic Intervention Under Medicaid
The primary objective of this study is to examine the usefulness of early orthodontic intervention as a means of increasing access to orthodontic services for children of low-income families.
- Trial name
- NCT00067379
- Testing
- interceptive orthodontic treatments
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Washington
Molar Incisor Hypomineralisation, Irreversible Pulpitis
Pain Assessment Governing Partial or Full Pulpotomy of Immature Molars With Irreversible Pulpitis in Molar Incisor Hypomineralization
This randomized controlled clinical trial aims to evaluate and compare pain levels associated with partial pulpotomy (PP) and full pulpotomy (FP) in immature permanent first molars diagnosed with irreversible pulpitis.
- Conditions
- Molar Incisor Hypomineralisation, Irreversible Pulpitis, Immature Molars
- Trial name
- NCT07850986
- Testing
- pulpotomy for MIH affected immature PFMs, partial pulpotomy for MIH affected immature PFMs, pulpotomy for non-MIH affected immature PFMs
- Where
- Egypt
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Alaa Khafagy
Nocturnal Bruxism
Investigation of Adolescents With Nocturnal Bruxism
The aim of this study is to examine the effects of bruxism on mandibular movement capacity, cervical proprioception, posture and quality of life in adolescents diagnosed with nocturnal bruxism (clenching and grinding teeth while…
- Trial name
- NCT06259786
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Karabuk University
Class II Division 2 Malocclusion
Changes in the Sagittal Pharyngeal Airway Dimension Following Leveling and Alignement in Class II Division 2 Patients
Aim of the study: is to compare the changes in the sagittal pharyngeal airway dimension (SPAD) and mandibular position before and after the levelling and alignment stage of orthodontic treatment in Class II division 2 patients.
- Trial name
- NCT06602518
- Testing
- Orthodontic Treatment
- Where
- Egypt
- Volunteers
- 27 people
- Sponsor
- Nourhan M.Aly
Class III Malocclusion
3D Printed Reverse Twin Block for Class III Malocclusion
This RCT aims to evaluate the effectiveness of a novel 3D printed reverse twin block appliance in the management of maxillary deficiency in growing patients having class III malocclusion.
- Trial name
- 3DRTB (NCT07710391)
- Testing
- 3D printed Reverse Twin Block appliance, Conventional Reverse Twin Block appliance
- Where
- Iraq
- Volunteers
- 30 people
- Sponsor
- University of Baghdad
Diet Habit, Family Characteristics
Nutrition, Physical Activity, Mediterranean Diet Adherence, and Children's Oral Health
The main risk factors for dental caries are inadequate oral hygiene practices, cariogenic bacteria, and cariogenic diet. Among these factors, diet has a different dual relationship with dental caries.
- Conditions
- Diet Habit, Family Characteristics, Tooth Decay, Periodontal Health
- Trial name
- NCT06130189
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Ankara Medipol University
Dental Caries, Gingivitis
Effect of Oral Health Education on Oral Health Status, Treatment Needs and Barriers to Care
Jordanian children have very poor oral hygiene parameters, and this is reflected as very high caries prevalence and poor gingival health conditions.
- Trial name
- NCT04317768
- Testing
- Basic oral health education and motivation, Intensive oral health education and motivation
- Where
- Jordan
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Caries Risk, Caries, Dental
Powered vs Manual Toothbrush Use: Its Effect on Caries Risk in Pre-Adolescents
This pilot study aims to evaluate dental caries experience in children ages 8-12 years old through comparing the use of a powered versus manual toothbrush, while using a standardized fluoride toothpaste as the control over the…
- Trial name
- NCT07859553
- Testing
- Powered toothbrush
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Michigan
Candidiasis, Oral
Relationship Between Oral Hygiene in Newborns and Candida Spp.
Little is known regarding the effectiveness of neonatal oral hygiene and its relationship to colonization by Candida spp. in edentulous oral cavities.
- Trial name
- NCT03873753
- Testing
- Cleaning, No oral cleaning
- Where
- Brazil
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- Faculty Sao Leopoldo Mandic Campinas
Dental Caries
Injectable Bioactive Composite vs Hall Technique for Proximal Cavities in Primary Molars
This randomized clinical trial compares the survival rate and clinical performance of injectable bioactive giomer composite restorations versus the Hall Technique for managing proximal carious lesions (ICDAS 3-4) in primary…
- Trial name
- NCT07552129
- Testing
- giomer, hall technique
- Volunteers
- 50 people
- Sponsor
- Cairo University
Malocclusion, Angle Class II
Efficacy of Minimally Invasive Surgical Technique in Accelerating Orthodontic Treatment
Thirty six patients needs therapeutic extraction of the maxillary first premolars with subsequent retraction of the maxillary canines will be divided randomly into two groups : piezocision group and the ER:yttrium aluminum garnet…
- Trial name
- NCT02606331
- Testing
- Piezosurgery, ER:YAG laser
- Where
- Syria
- Volunteers
- 36 people
- Sponsor
- Damascus University
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