Clinical trials: Tooth Plaque, open to volunteers
Dental Plaque and Gingivitis, Oral Hygiene Reinforcement During Fixed Orthodontic Treatment
Mobile Application Push Notification in Improving Oral Hygiene Behaviour in Adolescent Orthodontic Patients
This research looks at whether using a mobile phone app that sends push-notification reminders can help adolescent orthodontic patients keep their teeth and gums cleaner during treatment.
- Trial name
- IMGS_EZGIGI (NCT07288853)
- Testing
- Ezgigi with push notification, EzGigi
- Where
- Malaysia
- Volunteers
- 78 people
- Sponsor
- Kumeran A/L Mohan
Orthodontic Pain (D013850), Malocclusion
Comparison of Three Orthodontic Separators for Pain, Plaque, and Tooth Separation
Orthodontic separators are small devices placed between teeth before fitting braces to create space for bands. This procedure may cause pain, discomfort, and changes in oral hygiene, which can affect plaque buildup and daily…
- Conditions
- Orthodontic Pain (D013850), Malocclusion, Orthodontic Treatment
- Trial name
- SEP-ORTHO (NCT07532044)
- Testing
- Elastomeric Separator, Kesling Separator, Tie wire separator
- Where
- Pakistan
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Islamabad Medical and Dental College
Specific Learning Disabilities, Dental Plaque
Plaque Removal Efficiency in Children With Specific Learning Disabilities
This study aims to evaluate the effectiveness of toothbrushing education on plaque removal in children aged 7-12 years with specific learning disabilities (SLD) and to compare their plaque removal performance with healthy…
- Conditions
- Specific Learning Disabilities, Dental Plaque, Oral Hygiene
- Trial name
- PRE-SLD (NCT07611942)
- Testing
- Standardized Toothbrushing Education
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University
Plaque-Induced Gingivitis, Dental Plaque Accumulation
Innovative Mouthwash in School-Aged Children With Fixed Orthodontic Appliances
Fixed metal orthodontic appliances create additional plaque-retentive areas around brackets, archwires and ligatures, making mechanical plaque control more difficult in children and adolescents.
- Conditions
- Plaque-Induced Gingivitis, Dental Plaque Accumulation, Halitosis
- Trial name
- NCT07710144
- Testing
- Test mouthwash, Chlorhexidine-containing mouthwash
- Where
- Bulgaria
- Volunteers
- 90 people
- Sponsor
- Plovdiv Medical University
Gingivitis, Healthy Adult
Comparative Evaluation of the Anti-Plaque and Anti-Gingivitis Effects of Nanobiofusion Gingival Gel (NBF), Placebo Gel, and Commercial Toothpaste
The goal of this clinical trial is to learn if Nanibiofusion Gingival Gel (NBF) is able to reduce dental plaque and gum inflammation in adults.
- Trial name
- NCT07850232
- Testing
- Nano Bio-Fusion (NBF) Gingival Gel, Commercial fluoride toothpaste
- Where
- Jordan
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Caries,Dental, Pain
Comparative Evaluation of SMART Hall Technique Vs. Conventional SS Crown in Primary Molars: a Randomized Clinical Trial
Dental caries, particularly in primary molars, significantly affects children's oral health and overall well-being. Traditional management with stainless steel crowns (SSCs) involves significant tooth reduction and advanced…
- Conditions
- Caries,Dental, Pain, Plaque, Dental, Gingival Bleeding
- Trial name
- RCT (NCT06453005)
- Testing
- SMART Hall Technique or procedure
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- C K S Teja Institute Of Dental Sciences & Research
Dental Caries, Periodontitis
Breaking the Cycle: Real-Time Family Oral Microbial Transmission Patterns as Intervention Targets
This study aims to understand how oral bacteria that cause tooth decay and gum disease spread among family members and whether treating multiple family members can reduce the return of these bacteria after dental treatment.
- Conditions
- Dental Caries, Periodontitis, Oral Microbiome, Bacterial Transmission
- Trial name
- NCT07674888
- Testing
- Professional Dental Plaque Disruption
- Where
- Canada
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Enamel Hypomineralization, Tooth Erosion
Hydroxyapatite Toothpastes and Enamel Remineralization:
This randomized controlled clinical trial aims to evaluate the efficacy of two commercially available toothpastes containing hydroxyapatite in the remineralization of early enamel lesions.
- Trial name
- HEREMI (NCT07069218)
- Testing
- Biorepair® Total Protection Plus Toothpaste, Bioniq® Toothpaste
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Pavia
Malocclusion
Evaluation of Clinical and Patient-Reported Outcomes of Laceback
The goal of this clinical trial is to evaluate oral hygiene status, archwire complications, laceback complications, and pain while using lacebacks in patients undergoing orthodontic fixed appliance treatment.
- Trial name
- NCT07039071
- Testing
- Laceback
- Where
- Malaysia
- Volunteers
- 38 people
- Sponsor
- International Islamic University Malaysia
Dental Plaque
Comparative Accuracy of AI Models and Clinical Assessment for Dental Plaque Detection in Children
This diagnostic accuracy study aims to evaluate the effectiveness of various artificial intelligence models in detecting dental plaque from intraoral images compared to clinical assessments performed by dentists among children.
- Trial name
- NCT06760104
- Testing
- Dental Plaque Detection Using AI Models
- Where
- Egypt
- Volunteers
- 323 people
- Sponsor
- Naema Ahmed
Dental Plaque Accumulation, Nanoparticles
Comparing the Antiplaque Effects of Novel Titania Nanoparticle Infused Fluoride Varnish vs Conventional Fluoride Varnish in Fixed Orthodontic Patients.
In this study the investigators aimed to explore the antibiofilm effect of fluoride varnish loaded with titania nanoparticles synthesized from moringa oleifera leaves extract vs conventional fluoride varnish in multibracket fixed…
- Conditions
- Dental Plaque Accumulation, Nanoparticles, Fluoride Varnishes
- Trial name
- NCT07180849
- Testing
- Fluoride varnish, Novel titania nanoparticle infused fluoride varnish
- Where
- Pakistan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Dental Plaque, Dental Caries
Probiotic Treatment of Orthodontic Patients
The purpose of this study is to examine the effect of treatment with a lozenge containing the probiotic strain S. salivarius M18 on the formation, composition and virulence of dental plaque and in healthy orthodontic patients…
- Trial name
- NCT06751979
- Testing
- Probiotic treatment
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Reduction in DMFT Index and Plaque Index in Patients at the Treatment Completion, an Average of 4 Years, DMFT Index, ICDAS Score, Dental Plaque Index, Communication, Prevention, Dentist, Orthodontist
A New Digital Communication Tool Between Dentist and Orthodontist to Improve Dental Prevention
Dentists and orthodontists of the oral medicine department of Reims University Hospital noted that many children presented white spots around orthodontic brackets, or decays at the end of their multi-brackets orthodontic…
- Trial name
- ComDentODFPrev (NCT06517238)
- Testing
- There is no intervention
- Where
- France
- Volunteers
- 30 people
- Sponsor
- CHU de Reims
Root Resorption, Plaque Accumulation
Comparison of Canine Retraction Using Ni-ti Closed-coil Springs Vs Elastomeric Power Chains During Orthodontic Treatment
The objective of this study is to compare the canine retraction rate (in mm with a 100 mm marked scale) using Ni-Ti closed-coil springs versus elastomeric power chains during canine retraction in subjects with first premolar…
- Conditions
- Root Resorption, Plaque Accumulation, Gingivitis
- Trial name
- NCT06567730
- Testing
- Ni-ti Closed-coil Spring, Elastomeric Power chain
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Munnal Gulzar
Dentinal Hypersensitivity, Plaque, Dental
Evaluation of Dental and Periodontal Health After IPR in Patients in Orthodontic Treatment With Clear Aligners
This study aimed to evaluate dental and periodontal health after interproximal enamel reduction and to compare Laser diode (a device used in the Orthodontic Program) and sodium fluoride (often used in the Orthodontic Program and…
- Conditions
- Dentinal Hypersensitivity, Plaque, Dental, Bleeding Gum
- Trial name
- NCT06685016
- Testing
- Evaluation of Dentin hypersensitivity with VAS scale
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Specific Learning Disabilities, Dental Caries
Dental Caries and Oral Hygiene Status in Children With Specific Learning Disabilities
This study aims to evaluate dental caries and oral hygiene status in children aged 7-12 years with specific learning disabilities (SLD) and to compare the findings with healthy children.
- Conditions
- Specific Learning Disabilities, Dental Caries, Oral Hygiene
- Trial name
- SLD-OH (NCT07611981)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University
Oral Hygiene in Patients With Fixed Orthodontic Appliances, Dental Plaque
Effectiveness of Personalized Digital Oral Health Intervention in Patients With Fixed Orthodontic Appliances.
This study will evaluate whether personalized digital oral-health education delivered through WhatsApp messages can improve oral hygiene in patients aged 16-25 years who wear fixed orthodontic appliances (braces).
- Conditions
- Oral Hygiene in Patients With Fixed Orthodontic Appliances, Dental Plaque, Gingivitis Infection
- Trial name
- PDHOI (NCT07910851)
- Testing
- Personalized Digital Oral Health Education via WhatsApp, Standard Oral-Hygiene Instructions
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Kurdistan Higher Council of Medical Specialties
Dental Caries
SDF vs Fluoride Varnish for Streptococcus Mutans Reduction in Children
This randomized split-mouth clinical trial will compare the effectiveness of 38% silver diamine fluoride (SDF) versus 5% sodium fluoride varnish (FV) in reducing salivary Streptococcus mutans levels in children with bilateral…
- Trial name
- Streptococcus (NCT07181967)
- Testing
- Sodium Fluoride Varnish (5%), Silver Diamine Fluoride (38%)
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Assiut University
Dental Plaque
Disclosing Agents as Photosensitizers in aPDT for Biofilm Control in Children
This randomized controlled clinical trial aims to evaluate the effectiveness of plaque disclosing agents used as photosensitizers in antimicrobial photodynamic therapy (aPDT) for the control of dental biofilm in children aged 3…
- Trial name
- NCT07539181
- Testing
- Mechanical Prophylaxis, aPDT with Erythrosine, aPDT with GC TriPlaque ID Gel
- Volunteers
- 72 people
- Sponsor
- University of Nove de Julho
pH, Microbiome
Oral Changes With Caloric and no Caloric Sweeteners
The objective of this clinical trial is to compare the effect that the intake of beverages without sweeteners, added with non-caloric sweeteners (stevioside) and caloric sweeteners (sucrose) on oral pH and dental biofilm…
- Conditions
- pH, Microbiome, Dental Plaque
- Trial name
- NCT05852145
- Testing
- Stevioside, Sucrose, Natural water
- Where
- Mexico
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Hospital Infantil de Mexico Federico Gomez