Clinical trials: Toothache
Injection Pain, Local Anesthesia Infiltration
Sweet-Tasting Solution Versus Placebo to Reduce Pain During Local Anesthetic Injection in Children
The goal of this clinical trial is to learn whether applying a sugar-free flavored sweet solution (SFSS) before local anesthesia helps reduce injection pain in children.
- Conditions
- Injection Pain, Local Anesthesia Infiltration, Pain, Injection Pain Prevention
- Trial name
- NCT07279285
- Testing
- Sugar-free-flavored sweet tasting solution
- Where
- Jordan
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Cerebral Palsy, Dental Diseases
Salivary Cytokine Profile as a Biomarker for Dental Pain
always reliable.Pain is an important diagnostic tool in dentistry. The type of treatment, extent of treatment and, sometimes, even the decision on whether to treat or not is dependent on the pain history obtained from the…
- Trial name
- NCT03471195
- Testing
- Total Salivary Cytokine profile
- Where
- Saudi Arabia
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Irreversible Pulpitis (Toothache)
Evaluation Of Laser Versus Conventional Pulpotomies In Mature Molar Teeth With Irreversible Pulpitis
this clinical trial is evaluating the outcome of laser assisted pulpotomy compared to conventional pulpotomy in mature teeth with symptomatic irreversible pulpitis (SIP) assessed by CBCT followed by automated segmentation using…
- Trial name
- NCT07287709
- Testing
- Diode laser, Sodium Hypochlorite Solution
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Rana Hegaz
Dental Pain, Dental Anxiety
Compare the Intensity of Pain Felt by Children During the Local Anesthesia Procedure to That Perceived by the Accompanying Parent.
The goal of this observational study is to compare the intensity of pain experienced by children (aged 6 to 15) during local anaesthesia with that perceived by the parent accompanying them.
- Trial name
- ADDenT (NCT07718477)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Clermont-Ferrand
Dental Anxiety, Dental Pain and Sensation Disorder
The Effectiveness of Audiovisual Distraction Behavior Guidance Technique in Children With Dental Anxiety
This randomized, two-armed, placebo-controlled, cross-over, controlled trial aimed to evaluate the effect of virtual reality exposure therapy (VRET) on dental anxiety, pain, and behaviour among children undergoing dental…
- Trial name
- NCT04226651
- Testing
- Virtual Reality Device, Protective glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Pain, Postoperative
Study to Find Out the Optimal Dose of Caffeine in the Combination Tablet of Naproxen Sodium and Caffeine in Patients Experiencing Moderate to Severe Pain After Having Wisdom Teeth Removed
The researchers in this study wanted to find out the optimal dose of Caffeine in the combination tablet of Naproxen Sodium and Caffeine that works in patients experiencing moderate to severe pain after having wisdom teeth…
- Trial name
- NCT04132336
- Testing
- Naproxen sodium/Caffeine (BAY2880376), Naproxen sodium (Aleve), Caffeine
- Where
- United States
- Volunteers
- 193 people
- Sponsor
- Bayer
Pain, Postoperative, Dental Pain
A Study of Acetaminophen for Post Surgical Dental Pain
To assess the safety, tolerability, analgesic, efficacy and pharmacokinetics of high dose acetaminophen relative to placebo and low dose acetaminophen relative to placebo over a 24 hour period in patient experiencing moderate to…
- Trial name
- NCT04018612
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Nevakar, Inc.
Postoperative Pain
A Study of Two Approved Drugs in the Treatment of Postoperative Dental Pain (0966-190)(COMPLETED)
The purpose of this study is to compare the safety and effectiveness of two approved drugs in the treatment of pain following dental surgery.
- Trial name
- NCT00092339
- Testing
- MK0966, rofecoxib
- Volunteers
- 125 people
- Sponsor
- Merck Sharp & Dohme LLC
Dental Anxiety, Dental Pain
Comfort-in Needle-Free Injection System in Pediatric Dental Anesthesia
This randomized split-mouth clinical trial evaluated the efficacy of the Comfort-in needle-free injection system compared with conventional dental injection for local anesthesia during pulpotomy treatment in children.
- Conditions
- Dental Anxiety, Dental Pain, Pulpotomy, Local Anesthesia
- Trial name
- NCT07585812
- Testing
- Comfort-in Needle-Free Injection System, Conventional Dental Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ondokuz Mayıs University
Orthodontic Appliance, Pain
The Effect of Intraoral Transcutaneous Electrical Nerve Stimulation in Orthodontics Pain
The goal of this clinical trial is to determine whether an intraoral Transcutaneous Electrical Nerve Stimulation (TENS) device can reduce pain during orthodontic alignment and leveling in adolescents and adults.
- Conditions
- Orthodontic Appliance, Pain, Transcutaneous Electric Nerve Stimulation, Orthodontic Appliance Complication
- Trial name
- NCT06573996
- Testing
- Active TENS Device
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of the Pacific
Dental Pain, Dental Anxiety and Child Behavior Are Assess in Response to Dental Injection
Effect of Computer-controlled vs. Conventional Injection on Pain and Anxiety in Children
This randomized controlled trial aims to compare the effectiveness of Computer-Controlled automatic injection device versus conventional injection techniques in pediatric dental patients.
- Trial name
- NCT07193342
- Testing
- computer controlled automatic injection (Star pen® system), conventional anesthetic syringe
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Future University in Egypt
Pain
To Evaluate the Safety and Efficacy of Acetaminophen 650 mg and 1000mg in Dental Pain After Surgery
The objective of this study is to evaluate the safety and efficacy of acetaminophen 650 mg and acetaminophen 1000 mg in dental surgery.
- Trial name
- NCT01115673
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 540 people
- Sponsor
- McNeil Consumer Healthcare Division of McNEIL-PPC, Inc.
Pain
Multiple Dose Dental Pain Study Of Ibuprofen Extended Release
The study hypothesis is that single and multiple doses of ibuprofen 600 mg ER caplets provide analgesic efficacy superior to placebo over 12-hour dosing intervals.
- Trial name
- NCT01266161
- Testing
- Ibuprofen 600 mg ER
- Where
- 2 sites in United States
- Volunteers
- 106 people
- Sponsor
- Pfizer
Dental Pain
Study of Long-Acting Acetaminophen in Postoperative Dental Pain
The purpose of the study is to evaluate the efficacy and safety of acetaminophen ER 1500 mg (two 750 mg tablets) over 10 to 12 hours in the dental pain model following third molar extraction(s) and to evaluate the…
- Trial name
- NCT01960114
- Testing
- Acetaminophen ER
- Where
- United States
- Volunteers
- 403 people
- Sponsor
- McNeil Consumer Healthcare Division of McNEIL-PPC, Inc.
Dental Anxiety, Dental Fear
The Effect of Rubber Dam on Objective and Subjective Parameters of Stress During Dental Treatment in Children
Although rubber dam application provides many advantages, several pediatric dentists avoid using it, arguing that it may increase stress for young patients.
- Conditions
- Dental Anxiety, Dental Fear, Rubberdam, Anesthesia, Dental
- Trial name
- NCT06779448
- Testing
- Evaluation of objective and subjective stress parameters caused by local anesthesia during treatments, Evaluation of objective and subjective stress parameters caused by topical anesthesia during treatments, Evaluation of objective and subjective stress parameters caused by the application of rubber dam during treatments in the patient and dentist
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Pain and Anxiety in Children With MIH
Preemptive Analgesia for Pain and Anxiety Control in Children With MIH
This randomized, triple-blinded clinical trial aims to evaluate the effect of preemptive analgesia using ibuprofen on pain perception and anxiety during restorative treatment of first permanent molars in children diagnosed with…
- Trial name
- NCT07374354
- Testing
- ibuprofen 100mg/ml oral suspension syrup
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- October University for Modern Sciences and Arts
Pain
Study Evaluating the Efficacy of an Ibuprofen Effervescent Tablet in the Treatment of Post-Surgical Dental Pain
Evaluation of the efficacy and safety of a single dose of an ibuprofen effervescent tablet in the treatment of pain following third molar extraction in comparison to single doses of placebo, standard ibuprofen tablets, and…
- Trial name
- NCT00631111
- Testing
- effervescent ibuprofen tablets, effervescent Aspirin plus Vitamin C tablets, ibuprofen tablets
- Where
- United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Dental Anxiety, Dental Fear
Virtual Reality Distraction During Dental Local Anesthesia Among Children
To evaluate the effect of virtual reality (VR) distraction on anxiety and pain during buccal infiltration anesthesia (BIA) in pediatric patients.
- Trial name
- NCT04483336
- Testing
- Virtual Reality Distraction, TV Screen Distraction
- Where
- Saudi Arabia
- Volunteers
- 50 people
- Sponsor
- King Abdulaziz University
Pain
Study Evaluating A Novel Ibuprofen Formulation In The Treatment Of Dental Pain
This study will compare the analgesic efficacy of a single-dose of a novel ibuprofen formulation to placebo and acetaminophen in the treatment of post-surgical dental pain following "wisdom" tooth (third molar) removal.
- Trial name
- NCT01216163
- Testing
- Novel Ibuprofen, Acetaminophen
- Where
- United States
- Volunteers
- 218 people
- Sponsor
- Pfizer
Dental Anaesthesia, Dental Pain
Photobiomodulation and Tooth Analgesia
The purpose of this study is to test photobiomodulation (PBM) with a non-invasive light device for reducing discomfort during dental treatments in children.
- Conditions
- Dental Anaesthesia, Dental Pain, Dental Analgesia
- Trial name
- NCT06691269
- Testing
- Photobiomodulation, Topical Benzocaine, Local Anesthesia
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore