Clinical trials: Trabeculectomy
Congenital Glaucoma
Combined Trab+Trab Versus Combined Trab+Trab With Subconjunctival Implantation of Ologen for Primary Congenital Glaucoma
The objective of this prospective randomised study is to compare the efficacy and safety of ologen CM (Collagen matrix) as adjunct to combined trabeculotomy-trabecuectomy in congenital glaucoma cases, the efficacy being the…
- Trial name
- NCT02121171
- Testing
- Ologen Collagen Matrix, Combined trabeculotomy-trabeculectomy
- Where
- Azerbaijan
- Volunteers
- 40 people
- Sponsor
- National Centre of Ophthalmology named after academician Zarifa Aliyeva
Pigmentary Dispersion Syndrome, Pigmentary Dispersion Glaucoma
IOP Reduction in Pigmentary Glaucoma Using DSLT
This study is a single-site, single-arm, prospective, observational study of IOP reduction after DSLT. Subjects will be assessed up to 12 months post-operatively.
- Trial name
- NCT07281391
- Testing
- Voyager DSLT
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Mann Eye Institute
Glaucoma, Adherence
Effect of SMS Reminder and Free Eye Drops on Follow-up Adherence After Trabeculectomy Surgery in Rural China
The purpose of the study is to use a randomized controlled design to determine the impact of a SMS messaging associated with free eye drops intervention on the following outcomes among patients after trabeculectomy surgery in…
- Trial name
- NCT02328456
- Testing
- SMS and free eye drops
- Where
- China
- Volunteers
- 209 people
- Sponsor
- Congdon Nathan
Glaucoma, Cataracts
Intraocular Pressure Control Following One Site Versus Two Site Combined Phacoemulsification/IOL And Trabeculectomy
The purpose of this study is to compare the safety \& effectiveness of the two types of cataract and glaucoma surgeries. Results from this study may improve the surgical and post surgical management and long term management of…
- Trial name
- NCT00695747
- Testing
- 2 Site procedure- Phacoemulsification/IOL and Trabeculectomy
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Lahey Clinic
Primary Open Angle Glaucoma
Results of Ocular Compression and Suture Release in Trabeculectomy and Combined Surgery
The use of ocular compression and suture release have helped to improve the safety and decrease the risks of glaucoma filtering surgery.
- Trial name
- NCT00327405
- Where
- United States
- Sponsor
- University of Cincinnati
Pediatric Aphakic Glaucoma
Trabeculectomy With MMC Versus Ahmed Glaucoma Implant for Treatment of Pediatric Aphakic Glaucoma
In this randomized clinical trial we compare trabeculectomy with mitomycin-C (T+MMC) and Ahmed glaucoma implant (AGI) in treatment of aphakic glaucoma in children under 16 years of age.Complete and qualified success were defined…
- Trial name
- NCT00371072
- Testing
- trabeculectomy with mitomycin-C
- Where
- Iran
- Sponsor
- Shahid Beheshti University of Medical Sciences
Glaucoma Patients Scheduled for Trabeculectomy
Comparison of Two Method Antimetabolites Application on Corneal Function in Trabeculectomy Surgery
Application of antimetabolite agents such as mitomycin_c has improved trabeculectomy results and better control of intraocular pressure complications such as corneal endothelial cell loss.
- Trial name
- NCT01297803
- Testing
- Mitomycin_c
- Where
- Iran
- Sponsor
- Shahid Beheshti University of Medical Sciences
Glaucoma
Study of PGA Suture in Ophthalmology
To evaluate the safety and efficacy of polyglycolic acid suture in ophthalmic surgical procedures
- Trial name
- NCT00351429
- Testing
- Polyglycolic acid suture
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Aurolab
Iris Incarceration
Subscleral Trabeculectomy With Iris Incarceration in Buphthalmous
Purpose: To evaluate a new modification for surgical treatment of Buphthalmous using subscleral trabeculectomy (SST) with iris incarceration Design: Prospective, randomized, consecutive interventional comparative study.
- Trial name
- NCT04129463
- Testing
- Subscleral Trabeculectomy (SST) with Iris incarceration, Conventional trabeculotomy
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Shaaban Elwan
Primary Congenital Glaucoma, Developmental Glaucoma
Ologen® Collagen Matrix in Patients With Primary Congenital Glaucoma Undergoing Trabeculectomy
To the best of Investigator knowledge, no studies to this date have compared the safety and efficacy of ologen® Collagen Matrix in Primary congenital glaucoma (PCG) patients undergoing trabeculectomy.
- Conditions
- Primary Congenital Glaucoma, Developmental Glaucoma, Infantile Glaucoma
- Trial name
- NCT03541551
- Testing
- CTT with ologen® Collagen Matrix, Trab Trab
- Where
- India
- Volunteers
- 44 people
- Sponsor
- L.V. Prasad Eye Institute
Steroid-Induced Glaucoma
Management Steroid Induced Glaucoma
Purpose: To assess the safety and efficacy of Viscotrabeculotomy Versus trabeculectomy with MMC for the management of medically uncontrolled steroid induced glaucoma.
- Trial name
- NCT04673201
- Testing
- Viscotrabeculotomy Versus trabeculectomy with "MMC"
- Where
- Egypt
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Primary Congenital Glaucoma, Pediatric Glaucoma
Subscleral Trabeculectomy With Inverted T-Shaped Deep Sclerectomy for Primary Congenital Glaucoma
Primary congenital glaucoma (PCG) is a vision-threatening disorder of childhood characterized by elevated intraocular pressure (IOP) resulting from developmental abnormalities of the anterior chamber angle.
- Conditions
- Primary Congenital Glaucoma, Pediatric Glaucoma, Intraocular Pressure
- Trial name
- TDS-PCG (NCT07701278)
- Testing
- Subscleral Trabeculectomy Combined With Inverted T-Shaped Deep Sclerectomy
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Benha University
Glaucoma
Effectiveness of a Procedure for Previously Failed Glaucoma Surgery
Transconjunctival mitomycin-C in needle bleb revision may be an effective procedure to treat cases with a previously failed trabeculectomy. We will investigate approximately 100 consecutive cases with follow up of up to 9 years.
- Trial name
- NCT00347789
- Testing
- Glaucoma surgery- Bleb revision
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Glaucoma Research & Education Group
Glaucoma, Trabeculectomy
Multidrug Resistance After Trabeculectomy With Mitomycin C
We investigate whether mitomycin C treatment during previous filtration surgery induces P-glycoprotein expression.
- Trial name
- NCT00449631
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University of Cologne
Open Angle Glaucoma
Micropulse Laser Trabeculoplasty (MLT) Versus Selective Laser Trabeculoplasty (SLT) for Treatment of Open Angle Glaucoma
The purpose of this study is to evaluate the effectiveness of a new laser (called Micropulse Laser Trabeculoplasty or MLT) in the treatment of glaucoma compared to the conventional laser presently used which is called selective…
- Trial name
- NCT01956942
- Testing
- Micropulse Laser Trabeculoplasty, Selective Laser Trabeculoplasty
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- David Belyea
Outcomes of Trabeculectomy With MMC
Trabeculectomy With MMC and I Stent in Uveitic Glaucoma and POAG : Outcomes and Prognostic Factors
1. determine whether cataract surgery has a major effect on outcomes of trabeculectomy with MMC or not. 2. Success rates of trabeculectomy with MMC in Queen Elizabeth hospital. 3. recurrence rate of uveitis after glaucoma surgery
- Trial name
- NCT03293251
- Testing
- Trabeculectomy with MMC
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Assiut University
Steroid Induced Glaucoma
Trabeculectomy With Ologen Collagen Implant vs Trabeculectomy With Provisc in Steroid Induced Glaucoma
The purpose of this prospective randomized study is to assess and compare the clinical efficacy and safety of primary trabeculectomy with Ologen® collagen implant and cohesive viscoelastic (Provisc®) - augmented trabeculectomy in…
- Trial name
- NCT01912638
- Testing
- Ologen Collagen Matrix, Provisc
- Where
- Azerbaijan
- Volunteers
- 17 people
- Sponsor
- National Centre of Ophthalmology named after academician Zarifa Aliyeva
Glaucoma, Congenital, Surgical Treatment
Inverted T Trabeculectomy Primary Congenital Glaucoma
This study aims to evaluate the safety and efficacy of novel Inverted T trabeculectomy in Primary Congenital Glaucoma (PCG). It enrolled 50 eyes of 25 children with PCG.
- Trial name
- Inverte T trab (NCT06837610)
- Testing
- Inverted T trabeculectomy
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Benha University
Glaucoma
A Trial of China Laser and Surgery Study Glaucoma in Rural China
Aims and Objectives (Quantitative) Aim: To compare the effectiveness of selective laser trabeculoplasty with trabeculoplasty in lowering the intraocular pressure in patients with medically uncontrolled open angle glaucoma in…
- Trial name
- NCT02955849
- Testing
- SLT laser
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Sun Yat-sen University
Control of Elevated Eye Pressure by Local and Systemic Therapy
Comparing Eye Pressure Using Maximal Tolerated Local Therapy or Systemic Acetazolamide
Local therapy for glaucoma is known to induce a conjunctival inflammation. Because of this, trabeculectomy is more likely to fail.
- Trial name
- NCT01274039
- Testing
- Acetazolamide for glaucoma patients to lower eye pressure
- Where
- Germany
- Sponsor
- University of Cologne