Clinical trials: Tranexamic Acid
Arthropathy of Knee
Alteration of Thrombelastography and Coagulation Function in Patients Undergoing Total Knee Arthroplasty With Intra-articular Tranexamic Acid Administration
The main aim and scope of this study is making comparison about the thrombelastography and coagulation function in patients before and after the total knee arthroplasty with intra-articular tranexamic acid administration.
- Trial name
- NCT05490160
- Testing
- Tranexamic acid
- Volunteers
- 54 people
- Sponsor
- RenJi Hospital
Dysplasia, Congenital Hip
Efficacy of Tranexamic Acid for Reducing Blood Loss and Blood Transfusion After Periacetabular Osteotomy
The goal of this randomized controlled, double-blinded trial is to assess the efficacy of intravenous tranexamic acid, a drug, in reducing blood loss and transfusion in patients undergoing periacetabular osteotomy, an elective…
- Trial name
- NCT02253810
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Hospital for Special Surgery, New York
Anterior Shoulder Instability
Tranexamic Acid for the Latarjet Procedure.
The investigators propose a double-blinded randomized study evaluating the effectiveness of tranexamic acid in reducing postoperative swelling and haematoma formation after the Latarjet procedure.
- Trial name
- NCT03458468
- Testing
- Tranexamic Acid, Saline
- Where
- Ireland
- Volunteers
- 100 people
- Sponsor
- Sports Surgery Clinic, Santry, Dublin
Hemorrhage, Surgical, Tonsillar Bleeding
TranExamic Atomized for Pediatric Post-Operative Tonsillectomy Hemorrhage: Pilot Study
After a child has their tonsils removed, sometimes they might bleed which can be a problem. There is a special mist medicine called nebulized tranexamic acid (TXA) that might help stop the bleeding without having to touch the…
- Trial name
- TEAPOT (NCT06580509)
- Testing
- Tranexamic Acid Injectable Product, Normal Saline
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Endobronchial Bleeding, Hemoptysis
The Efficacy of Tranexamic Acid and Adrenaline to Control Endobronchial Bleeding
During bronchoscopy (a procedure using a thin, flexible camera to look inside the airways), doctors sometimes take small tissue samples (biopsies) to diagnose lung conditions. This can cause bleeding in the airway.
- Trial name
- CATER (NCT07759089)
- Testing
- Adrenaline, Tranexamic Acid
- Where
- Pakistan
- Volunteers
- 76 people
- Sponsor
- Sheikh Zayed Federal Postgraduate Medical Institute
Blood Loss, Anatomic Total Shoulder Arthroplasty
Investigation of Intravenous Tranexamic Acid With Anatomic and Reverse Total Shoulder Arthroplasty
To compare intravenous Tranexamic Acid (TXA) versus normal saline placebo to determine whether or not TXA administration reduces blood loss, decrease in hemoglobin, and rate of transfusions following anatomic and reverse total…
- Conditions
- Blood Loss, Anatomic Total Shoulder Arthroplasty, Reverse Total Shoulder Arthroplasty, Transfusion
- Trial name
- NCT02569658
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Craniosynostosis Patients Undergoing Distraction Osteotomy
Effect of Tranexamic Acid Based on Pharmacokinetics in Pediatric Patients Undergoing Craniosynostosis Surgery: Randomized Controlled Trial
Massive bleeding is expected when performing distraction osteotomy for craniosynostosis patients. Since such operation is performed at very young age, many efforts are performed in order to reduce the total amount of bleeding and…
- Trial name
- NCT02180321
- Testing
- Tranexamic Acid, normal saline
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Osteo Arthritis Knee
Tranexamic Acid in Total Knee Replacement
Multiple intravenous Tranexamic Acid doses can reduce postoperative blood loss and improve the functional outcome in total knee arthroplasty without tourniquet: a randomized controlled study.
- Trial name
- NCT03656445
- Testing
- Tranexamic Acid
- Volunteers
- 180 people
- Sponsor
- Democritus University of Thrace
Tranexamic Acid, Pulmonary Hemorrhage
Impact of Inhaled Tranexamic Acid in Pulmonary Hemorrhage in Pediatric Intensive Care Unit
This study aimed to detect the impact of inhaled Tranexamic acid® in pulmonary hemorrhage in pediatric intensive care unit.
- Conditions
- Tranexamic Acid, Pulmonary Hemorrhage, Pediatric, Intensive Care Unit
- Trial name
- NCT07481682
- Testing
- Tranexamic acid + conventional therapy., Tranexamic acid
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Metastasis Spinal Tumor
Tranexamic Acid Use for Bleeding Prevention in the Surgical Treatment of Metastatic Spinal Tumor in Lung Cancer Patients
Massive blood loss occurs in metastatic spinal tumor resection and may cause severe complications. The objective of this study is to investigate whether the use of tranexamic acid will reduce perioperative and postoperative…
- Trial name
- NCT06023212
- Testing
- Tranexamic Acid, stroke-physiological saline solution (SPSS)
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Gastrointestinal Bleeding
Haemorrhage Alleviation With Tranexamic Acid- Intestinal System
Severe bleeding in the digestive system is a common symptom of many diseases. Each year, about 50,000 people end up in British hospitals because of this problem and about 5,000 of them die.
- Trial name
- HALT-IT (NCT01658124)
- Testing
- Tranexamic Acid
- Where
- United Kingdom
- Volunteers
- 12,009 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Traumatic Brain Injury
Evaluating the Effect of Tranexamic Acid on the Clinical Outcomes in Patients With Traumatic Brain Injury
Evaluate the effect of tranexamic acid on mortality in pediatric patients with traumatic brain injury. This could potentially lead to improved treatment protocols and better outcomes for this vulnerable population.
- Trial name
- NCT06330935
- Testing
- Tranexamic Acid (TXA), Normal saline
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University
Postpartum Hemorrhage
The Efficacy of Tranexamic Acid in Preventing Postpartum Haemorrhage After Caesarean Section
This study seeks to determine if the using tranexamic acid prophylactically at caesarean section will prevent postpartum haemorrhage which is a major cause of maternal mortality in Zimbabwe and globally.
- Trial name
- ETAPPH (NCT04733157)
- Testing
- Tranexamic acid injection
- Where
- 2 sites in Zimbabwe
- Volunteers
- 1,226 people
- Sponsor
- University of Zimbabwe
Tonsillectomy, Adenoidectomy
Tranexamic Acid and Pediatric Adenotonsillectomy
The purpose of this study is to determine if the use of tranexamic acid prior adenotonsillectomy in children can reduce surgical and postoperative bleeding.
- Conditions
- Tonsillectomy, Adenoidectomy, Tranexamic Acid
- Trial name
- NCT01228136
- Testing
- Tranexamic Acid, normal saline solution
- Where
- Brazil
- Volunteers
- 95 people
- Sponsor
- Irmandade Santa Casa de Misericórdia de Porto Alegre
Rotator Cuff Tears, Rotator Cuff Rupture
Arthroscopic Rotator Cuff Repair Performed With Intraarticular Tranexamic Acid Could it Provide Improved Visual Clarity and Less Post-operative Pain? A Prospective, Double Blind, Randomized Study of 64 Patients.
Shoulder arthroscopy is widely used for treatment of different shoulder pathologies. Visual clarity is essential for successful and safe surgery.
- Conditions
- Rotator Cuff Tears, Rotator Cuff Rupture, Tranexamic Acid, Shoulder Arthroscopy
- Trial name
- NCT05453266
- Testing
- Application of Tranexamic acid in arthroscopic irrigation solution, No application of Tranexamic acid in arthroscopic irrigation solution
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Florence Nightingale Hospital, Istanbul
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Extended Post-Operative Oral Tranexamic Acid Dosing After ACL Reconstruction
The goal of this clinical trial is to learn whether taking oral tranexamic acid (TXA) for one week after anterior cruciate ligament (ACL) reconstruction improves recovery in adolescents and young adults aged 14 to 25 years.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Pain, Postoperative
- Trial name
- NCT07880743
- Testing
- Tranexamic Acid
- Where
- 6 sites in United States
- Volunteers
- 100 people
- Sponsor
- Dave Bernholt
Heart Defect, Congenital
Tranexamic Acid Effect on Platelet Aggregation Following Infant Cardiopulmonary Bypass
Tranexamic acid is a relatively safe medicine that is used to help the body develop clots and slow down bleeding after large surgeries.
- Trial name
- NCT02122679
- Testing
- Tranexamic Acid
- Where
- United States
- Sponsor
- Emory University
Hemorrhage, Surgical, Tonsillar Bleeding
TEAPOT Study Multisite
After a child has their tonsils removed, sometimes they might bleed which can be a problem. There is a special mist medicine called nebulized tranexamic acid (TXA) that might help stop the bleeding without having to touch the…
- Trial name
- TEAPOT (NCT07565753)
- Testing
- Tranexamic Acid Injectable Product, Normal Saline
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Placenta Previa
Tranexamic Acid Use in Elective Cesarean Section for Women With Placenta Previa
Tranexamic Acid Use in Elective Cesarean Section for Women With Placenta Previa
- Trial name
- NCT03060889
- Testing
- Tranexamic acid
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Chronic Rhinosinusitis With Polyposis, Chronic Hyperplastic Sinusitis
Intravenous Tranexamic Acid and Intraoperative Visualization During Functional Endoscopic Sinus Surgery
Functional endoscopic sinus surgery (FESS) is an effective treatment of sinus disease. FESS is carried out using cameras to view the surgical field. Bleeding during the surgery can lead to poor surgical field visualization.
- Trial name
- NCT01111669
- Testing
- Tranexamic Acid
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Alberta