Clinical trials: Transgender
Pregnancy Related, Cardiac Output
Cardiac Flow Measurements in Pregnant Women by Non Invasive Techniques
the goal of this clinical trial is to compare the measurement of cardiac output, systolic ejection volume and vascular filling in pregnant women with the new non-invasive measurement techniques of the Index of contractility…
- Trial name
- NCT06114147
- Testing
- trans thoracic echocardiography measure, ICON measure, USCOM
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Geneva, Switzerland
Intracranial Hypertension
Non Invasive Measurement With Trans Cranial Doppler Versus Invasive Measurement in Pediatric Age
An increase of intracranial pressure (ICP) is an important cause of secondary brain damage. The gold standard for measuring ICP is represented by invasive positioning of intracranial ICP devices.
- Trial name
- nICPped (NCT05340062)
- Testing
- bedside sonography
- Where
- 6 sites in Italy
- Volunteers
- 46 people
- Sponsor
- Azienda Ospedaliera di Padova
DNS
Trans-septal Quilting Suturing vs Intranasal Silicone Splinting in Septoplasty
There is currently little data comparing intranasal silicone splinting versus trans-septal quilted suturing in terms of preventing problems following septoplasty.
- Trial name
- NCT07537920
- Testing
- trans-septal quilting suturing, intranasal silicone splinting
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Shahida Islam Medical Complex
Transgendered Persons
Trans Health: Evaluation of Markers of Cardio-metabolic Health and Well-being in Transgender Youth
This study plans to learn more about puberty blockers and cross (testosterone and estradiol). There is not much known about how these medications affect hormone levels, heart health and overall general health in young transgender…
- Trial name
- NCT02550431
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- University of Colorado, Denver
HIV Prevention
Digital Limited Interaction Efficacy Trial of LifeSkills Mobile to Reduce HIV Incidence in YTW
The LifeSkills Mobile app will be evaluated in a randomized controlled trial (RCT) among 5,000 young transgender women (YTW), ages 16-29 in the United States (U.S.).
- Trial name
- LifeSkills (NCT05018611)
- Testing
- LifeSkills Mobile
- Where
- United States
- Volunteers
- 5,100 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
HIV/AIDS, Gender
Transgender Youth and PrEP: PK, Safety, Uptake & Adherence - Demonstration Project
To address the critical scientific gaps in PrEP safety for transgender youth and to plan for appropriate implementation of PrEP in transgender youth communities, the study will be conducted in 3 integrated phases.
- Conditions
- HIV/AIDS, Gender, Behavior and Behavior Mechanisms
- Trial name
- NCT04077151
- Testing
- PrEP Demonstration Project
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Hektoen Institute for Medical Research
Pain, Postoperative
Trans-incisional vs Laparoscopic Guided Rectus Sheath Block for Pediatric Single Incision Laparoscopic Cholecystectomy
This is a prospective, double-blinded, randomized controlled study comparing the efficacy of trans-incisional rectus sheath block to laparoscopic guided rectus sheath block for pediatric single-incision laparoscopic…
- Trial name
- NCT02494336
- Testing
- Trans-incisional rectus sheath block, Laparoscopic guided rectus sheath block, Ropivacaine
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Johns Hopkins All Children's Hospital
Hernia Inguinal
A Comparative Study Between TAPP and Lichtenstein Techniques for Inguinal Hernia Surgery
This study is comperative study between TAPP And Lichtenstein Techniques for Inguinal Hernia surgery.The Lichtenstein tension-free open hernioplasty involves placing a tailored polypropylene mesh over the inguinal canal defect…
- Trial name
- NCT07067281
- Testing
- Lichtenstein Tension-Free Mesh Hernioplasty, Laparoscopic Transabdominal Preperitoneal (TAPP) Repair
- Where
- India
- Volunteers
- 60 people
- Sponsor
- GSVM Medical College
Acute Promyelocytic Leukemia With t(15;17)(q24.1;q21.2); PML-RARA
Tretinoin and Arsenic Trioxide in Treating Patients With Untreated Acute Promyelocytic Leukemia
This phase III trial studies tretinoin and arsenic trioxide in treating patients with newly diagnosed acute promyelocytic leukemia.
- Trial name
- NCT02339740
- Testing
- Arsenic Trioxide, Cytarabine, Dexamethasone
- Where
- 174 sites in United States, Australia and 4 more
- Volunteers
- 158 people
- Sponsor
- Children's Oncology Group
Gender Identity
TRANSLATE: Transgender and Gender Nonconforming Individuals' Access to Healthcare
Transgender and gender nonconforming (TGNC) individuals face a number of health disparities, many of which can be tied to a lack of access to or use of primary care.
- Trial name
- NCT03808883
- Testing
- TGNC Directed Advocacy Meetings, Facilitated Dialogues between TGNC Cohort and Healthcare Participants
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Transgender
Body Composition Assessment in Transgender Population.
Gender-affirming hormone therapy (GAHT) is a fundamental component of medical transition in transgender men, promoting body composition changes that align physical characteristics with gender identity and alleviate gender…
- Trial name
- BIVATRANS (NCT07481942)
- Testing
- gender affirming hormone therapy
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Celia Bañuls
Labor Stage, Second, Labor and Delivery
Visual Biofeedback Through Transperineal Ultrasound During the Expulsive Phase of Labour to Improve Maternal Childbirth Satisfaction
Childbirth is generally regarded as a positive life-changing experience. Up to 44% of women may however experience this as a traumatic event, with 3% suffering from post-traumatic stress disorder after childbirth.
- Conditions
- Labor Stage, Second, Labor and Delivery, Satisfaction With Care, Childbirth
- Trial name
- RCT:VB-TPU (NCT06847308)
- Testing
- visual biofeedback through trans-perineal ultrasound
- Where
- Belgium
- Volunteers
- 488 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Chronic Lung Disease of Prematurity, Chronic Respiratory Failure
Safe Use of Speaking Valve in Children During Sleep Using Trans-tracheal Pressure Measurement
Many children who are born medically fragile due to prematurity, multiple congenital abnormalities or an acquired insult (i.e. cardiac, neurologic, etc.) may require tracheostomy tube placement due to need of chronic respiratory…
- Trial name
- NCT02935140
- Volunteers
- 8 people
- Sponsor
- St Mary's Hospital for Children
Health Services for Transgender Persons, Transgender Persons
Comparing Subcutaneous Testosterone to Intramuscular Testosterone in Gender Affirming Care of Transgender Male Adolescents
The trial studies the efficacy of subcutaneous (SQ) testosterone compared to intramuscular (IM) testosterone therapy during the first 6 months of pubertal induction in transgender male adolescents.
- Trial name
- NCT03864913
- Testing
- Testosterone injection, PedsQL questionnarie, Masculinizing effects questionnaire
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Clinical Decision-Making, Gender Identity
Impact of Gender Identity on Dentists' Clinical Decision-Making
This randomized study evaluated whether patient gender identity influences dentists' clinical decision-making. Dentists in southern Brazil were randomly assigned to receive one of two versions of the same hypothetical dental…
- Conditions
- Clinical Decision-Making, Gender Identity, Transgender Persons
- Trial name
- GID-CDM (NCT07675564)
- Testing
- Clinical Case Scenario
- Where
- Brazil
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Santa Maria
Urethral Caruncle
Effectivity and Safety Study of Trans-artificial-urethral Resection of Female Urethral Caruncle
To explore the minimally invasive and exhaustive treatment of female urethral canruncle by using trans-artificial-urethral resection of the canruncle.
- Trial name
- NCT02490228
- Testing
- TAURFUC
- Volunteers
- 100 people
- Sponsor
- Peking University First Hospital
Nasolabial Cyst
Trans-nasal Complete Nasolabial Cyst Excision
Background: Nasolabial cysts are rare benign epithelial nonodontogenic soft tissue cysts arising in the nasal alar region. Sublabial excision or transnasal endoscopic marsupialization is the standard treatment.
- Trial name
- NCT05532462
- Testing
- Trans-nasal complete nasalabial cyst excision
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sohag University
HIV/AIDS, Gender
Transgender Youth and PrEP: PK, Safety, Uptake & Adherence - Intervention Development
To address the critical scientific gaps in PrEP safety for transgender youth and to plan for appropriate implementation of PrEP in transgender youth communities, the study will be conducted in 3 integrated phases.
- Conditions
- HIV/AIDS, Gender, Behavior and Behavior Mechanisms
- Trial name
- NCT04077138
- Where
- 3 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hektoen Institute for Medical Research
Juvenile Osteochondritis Dissecans
Study of Two Surgical Drilling Techniques to Treat Juvenile Osteochondritis Dissecans of the Knee
The purpose of this study is to compare the functional, clinical and radiographic outcomes associated with trans-articular drilling versus retro-articular drilling, two commonly employed techniques of operative treatment for…
- Trial name
- NCT01754298
- Testing
- Retro-articular drilling, Trans-articular drilling
- Where
- 14 sites in United States, Canada
- Volunteers
- 91 people
- Sponsor
- Boston Children's Hospital
Violence, HIV
#ChopViolence/#ChopHIV
Black young gay, bisexual and other men who have sex with men (B-YGBMSM) and transgender women (B-YTW) are disproportionately affected by HIV/AIDS in the U.S.
- Trial name
- NCT04769492
- Testing
- #ChopViolence/#ChopHIV
- Where
- United States
- Volunteers
- 525 people, healthy volunteers welcome
- Sponsor
- Hektoen Institute for Medical Research