Clinical trials: Transplant Donation
Normal Donors
Pilot Study of Educational Interventions in Pediatric Hematopoietic Stem Cell Donors to Increase Knowledge of Donation and Transplantation Procedures
Background: Hematopoietic Stem Cell Transplant (HSCT) represents the second most frequent major organ transplant in the United States.
- Trial name
- NCT01445158
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- National Cancer Institute (NCI)
End Stage Renal Disease, Transplantation
Live Kidney Donor Study - Cross-Sectional and Historical Cohort Study
Kidney transplantation from living donors has been shown to carry many benefits over deceased donor transplantation. Because of benefits such as shorter waiting times and improved outcome for transplant recipients, living kidney…
- Trial name
- NCT00951977
- Where
- 3 sites in United States
- Volunteers
- 7,029 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Deceased Organ Donation, Critical Illness
National Observational Study of Clinical Practices in Deceased Organ Donation
This is a 1-year national prospective cohort study that observes the medical management of consented deceased organ donors at hospitals across Canada with a high volume of deceased donation.
- Conditions
- Deceased Organ Donation, Critical Illness, Transplantation
- Trial name
- CanadaDONATE (NCT03114436)
- Testing
- Observational Data Collection
- Where
- 29 sites in Canada
- Volunteers
- 622 people
- Sponsor
- McMaster University
Disorder Related to Bone Marrow Transplantation, Blood Stem Cell Transplant Failure
Long Term Minor Sibling Donor Well-Being
The goal of this research study is to understand what it is like for a young person to have a sick family member and what it is like to donate bone marrow or stem cells for a sick family member. Primary Aims: 1.
- Conditions
- Disorder Related to Bone Marrow Transplantation, Blood Stem Cell Transplant Failure, Disturbance of Emotions Specific to Childhood and Adolescence, Transmission, Blood, Recipient/Donor
- Trial name
- NCT00667784
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Heart Failure
Coronary Artery Disease in Hearts Donated for Transplantation
In spite of recent initiatives, in particular, the introduction into clinical practice of donation after circulatory death (DCD), there is a persistent mismatch between the demand for donor hearts for transplantation and their…
- Trial name
- NCT06528834
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Nephrectomy
Recovery of Short-term Renal Function in Post-transplant Patients Living Donor
Objectives: To describe and analyze the perioperative and functional evolution of short-term renal graft in patients with kidney transplantation from a live donor, comparing three surgical techniques for obtaining kidney graft…
- Trial name
- NCT03717259
- Testing
- Open nephrectomy, Hand-assisted laparoscopic nephrectomy, Laparoscopic nephrectomy
- Volunteers
- 508 people
- Sponsor
- Instituto Mexicano del Seguro Social
End-stage Renal Disease, Chronic Kidney Diseases
Increasing Live Donor Kidney Transplantation Through Video-based Education and Mobile Communication
The study is a- 2-arm randomized controlled trial among patients presenting for kidney transplant evaluation at a single transplant center to compare the effects of a patient-based self-learning and outreach intervention about…
- Trial name
- KidneyTIME (NCT05154773)
- Testing
- Kidney donation and transplant information made easy
- Where
- United States
- Volunteers
- 422 people
- Sponsor
- State University of New York at Buffalo
Kidney Transplant
Knowledge and Attitude of Dialysis Center Medical Staff Towards Living Kidney Donation
The goal of this cross-sectional study is to learn about the level of knowledge and attitudes of medical staff working in dialysis centers about living kidney donations.
- Trial name
- NCT05797337
- Where
- Poland
- Volunteers
- 500 people
- Sponsor
- Andrzej Frycz Modrzewski Krakow University
Hematopoietic/Lymphoid Cancer
Hematopoietic Stem Cell Transplantation and Childhood Leukemia Quality of Life in SIbling DONors
The childhood cancer experience necessarily impacts the entire family. In this context, particular attention should be paid to the donor siblings of hematopoietic stem cells in the context of treatment of leukemia by grafting.
- Trial name
- SIDONY (NCT03659071)
- Testing
- questionnaire VSP-A
- Where
- France
- Volunteers
- 1,187 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Organ Donation
Donation Advisor Clinical Decision Support Tool Study
Every year, thousands of Canadians receive life-saving, cost-effective organ transplants, while thousands more still wait or die because not enough organs are available.
- Trial name
- NCT04661787
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- Ottawa Hospital Research Institute
Kidney Diseases, Kidney Failure
Enhance Access to Kidney Transplantation and Living Kidney Donation
Compared to dialysis, kidney transplantation is associated with improved survival, better quality of life and substantial cost savings to healthcare systems.
- Conditions
- Kidney Diseases, Kidney Failure, End Stage Renal Disease
- Trial name
- EnAKT LKD (NCT03329521)
- Testing
- Multicomponent intervention
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Kidney Donation, Kidney Failure
Live Kidney Donor Study -Renal Function Study
Kidney transplantation from living donors has been shown to carry many benefits over deceased donor transplantation. Because of benefits such as shorter waiting times and improved outcome for transplant recipients, living kidney…
- Conditions
- Kidney Donation, Kidney Failure, Kidney Transplantation
- Trial name
- NCT01158742
- Testing
- Glomerular Filtration Rate with Iothalamate, Glomerular Filtration Rate with Iohexol
- Where
- 3 sites in United States
- Volunteers
- 402 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Brain Death, Organ Donation
Goal of Open Lung Ventilation in Donors
The primary goal of this study is to assess whether ventilation of deceased organ donors with an open lung protective ventilatory strategy will improve donor lung utilization rates and donor oxygenation compared to a conventional…
- Conditions
- Brain Death, Organ Donation, Organ Transplant Failure or Rejection
- Trial name
- GOLD (NCT03439995)
- Testing
- Open lung protective ventilation, Conventional ventilation
- Where
- 4 sites in United States
- Volunteers
- 154 people
- Sponsor
- Vanderbilt University Medical Center
Transplant Recipient, Transplant Donation
University of Minnesota Transplant Registry
Under Transplant Information Services (TIS), the University of Minnesota Transplant Registry (UMTR) will serve as the repository for core research data.
- Trial name
- NCT01062581
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- University of Minnesota
Liver Transplantation
Post-Static Cold Storage Hypothermic Oxygenated Perfusion in Bergamo Liver Transplant Program
In light of the widespread organ shortage, dynamic preservation by means of Machine Perfusion (MP) has been proposed as a strategy to increase the pool of suitable grafts for liver transplantation.
- Trial name
- NCT03098043
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Papa Giovanni XXIII Hospital