Clinical trials: Trauma Patients in ICU
Critical Illness, Pediatrics
Effect of Giving Reduced Fluid in Children After Trauma
This study is designed to help decide how much intravenous (IV) fluid should be given to pediatric trauma patients. No standard currently exists for managing fluids in critically ill pediatric trauma patients, and many fluid…
- Conditions
- Critical Illness, Pediatrics, General Surgery, Fluid Therapy
- Trial name
- NCT04201704
- Testing
- Balanced crystalloid solution volume administration, Packed Erythrocytes Units, Blood Product Unit volume, Plasma volume
- Where
- 4 sites in United States
- Volunteers
- 250 people
- Sponsor
- Columbia University
Influenza, Acute Lung Injury
Immuno-virological Characterization of Severe H1N1v Influenza Infection in Bronchoalveolar Lavage
The influenza A/H1N1v pandemic virus causes severe pneumonia that can lead to acute respiratory distress syndrome and death even in healthy young individuals.
- Conditions
- Influenza, Acute Lung Injury, Acute Respiratory Distress Syndrome
- Trial name
- FluBAL (NCT01089400)
- Where
- 2 sites in France
- Volunteers
- 30 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Traumatic Brain Injury With Prolonged Loss of Consciousness
A Trial to Determine the Feasibility and Effectiveness of Early Multisensory Stimulation Intervention in Patients in the Trauma-Neurosurgical Intensive Care Unit (TNICU) Following Severe Acquired Brain Injury
St. Michael's Hospital (SMH) provides service to individuals with some of the most severe brain injuries and intensive care needs in Canada.
- Trial name
- NCT02589223
- Testing
- Multisensory Stimulation, Control
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- Unity Health Toronto
Acute Kidney Injury
Iatrogenic Deficiencies in ICU Patients With Prolonged Continuous Renal Replacement Therapy
ICU patients are recruited after at least 5 days treatment with continuous renal replacement therapy. Blood samples are drawn at time of recruitment and then every 3-5 days until ceseation of renal replacement therapy.
- Trial name
- IBRIST (NCT06983197)
- Testing
- blood test
- Volunteers
- 30 people
- Sponsor
- Karolinska University Hospital
Mechanical Ventilation Complication
Cross-sectional, Observational, Prospective and Analytical Study:MECHANICAL POWER DAY (MPDay)
Recently the new concept of "mechanical power" has been proposed. It refers to the amount of energy per minute that is transferred to the lung by the ventilator.
- Trial name
- MPDay (NCT03936231)
- Testing
- NO Intervention
- Where
- Spain
- Volunteers
- 2,000 people
- Sponsor
- Hospital Universitario Marqués de Valdecilla
Major Trauma, Traumatic Brain Injury
Severe Trauma Registry in Tarragona
Severe trauma is one of the leading causes of morbidity, mortality, and disability worldwide. Currently, it is the primary cause of death among individuals under 45 years of age.
- Trial name
- IcuTrauma (NCT06007807)
- Where
- Spain
- Volunteers
- 1,000 people
- Sponsor
- Hospital Universitari Joan XXIII de Tarragona.
Severe Trauma (With or Without Traumatic Brain Injury)
Post Traumatic Critical Complications: a Prospective Cohort Study (ATLANREA)
The purpose of this observational epidemiological study is to investigate the management and the complications associated with severe trauma.
- Trial name
- NCT02426255
- Testing
- Collection of medical data from ICU patients
- Where
- 5 sites in France
- Volunteers
- 5,000 people
- Sponsor
- Nantes University Hospital
Trauma (Including Fractures), Trauma ICU Patients
Mortality of Trauma in the Intensive Care Unit.
In this study, it was planned to establish the factors associated with severe trauma discharged from the intensive care unit and mortality.
- Conditions
- Trauma (Including Fractures), Trauma ICU Patients, Trauma Injury, Trauma Patients in ICU
- Trial name
- MOTRAM-ICU-COL (NCT07208110)
- Testing
- Exposed to trauma, Not exposed
- Where
- Colombia
- Volunteers
- 500 people
- Sponsor
- Hospital Departamental de Villavicencio
Limb Fracture
Impact of Continuous Regional Analgesia in Severe Trauma Patients
Regional analgesia, based on its physiological effects and efficacy, is used for optimal perioperative pain relief. However, for acute pain in multiple trauma patients in a critical condition, it has not been prospectively…
- Trial name
- ALRréa (NCT04546503)
- Testing
- Continuous Regional analgesia, Control Group
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
The Usefulness of Specific Scores in Predicting Mortality of Patients With Head Trauma in ICU
Predictors of Mortality Among Patients With Head Trauma
Evaluate the usefulness of the APACHE II (Acute Physiology and Chronic Health Evaluation II), RTS (Revised trauma score), GCS (Glasgow Coma Scale) scores and various variables as age, sex, lab.data and complications in predicting…
- Trial name
- NCT06922396
- Testing
- Parameters on admission
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Ayman Mahmoud Alsayes
Acute Kidney Injury
Role of Some Biochemical Indices for Prediction of Acute Kidney Injury in Intensive Care Unit Patients in Upper Egypt
1. We will investigate the relation between the triglyceride-glucose index and the development of AKI in ICU. 2. To detect whether the TGI is a predictor of poor outcome (requirement of renal replacement therapy, or 14-day…
- Trial name
- NCT06791200
- Testing
- biochemical indices
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Delirium, Trauma
Incidence and Risk Factors for Delirium in Severely Injured Patients
Delirium is very common in intensive care unit (ICU) patients and leads to poor outcomes. There is little information on delirium in injured patients however.
- Conditions
- Delirium, Trauma, Intensive Care Unit Syndrome
- Trial name
- NCT03023839
- Where
- South Korea
- Volunteers
- 179 people
- Sponsor
- Asan Medical Center
Critical Illness, Pressure Injuries
Abdominal Massage and Range-of-motion Exercise in Enterally Fed ICU Patients With Pressure Injuries
The purpose of this study is to evaluate whether two nursing interventions, lower abdominal massage and range-of-motion (ROM) exercises (gentle movements of the arm and leg joints), affect the healing of pressure injuries (bed…
- Conditions
- Critical Illness, Pressure Injuries, Enteral Nutrition Intolerance in Critically Ill Patients
- Trial name
- pressure injur (NCT07904520)
- Testing
- LAM group, Intervention and control-group data were collected daily at 10:00 AM. In the intervention groups, each 15-minute session was followed by outcome measurements the next day before the following session,, ROM
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bartın Unıversity
Ventilator Lung; Newborn
NIPE as an Indicator of Pain in Sedated/Ventilated Patient Under 3 Years-old Hospitalized in Intensive Care Unit
The main objective is to assess correlation between Newborn Infant Parasympathetic Index values and external evaluation by Comfort Behaviour Scale during painful medical cares in sedated intubated children admitted in pediatric…
- Trial name
- NIPE (NCT04195672)
- Testing
- NIPE (MDoloris®) and CBS values
- Where
- France
- Volunteers
- 32 people
- Sponsor
- University Hospital, Lille
Secondary Hypothyroidism
Thyroid Function in Critically Ill Patients With Acute Kidney Injury
The objective of this study was to assess the changes in thyroid hormones and its activity during CRRT in patients with Acute Kidney Injury.
- Trial name
- NCT04767763
- Testing
- Assessment of TSH, fT3, fT4,TRH, TT3, TT4, rT3 in patients with CVVHDF
- Where
- Poland
- Volunteers
- 32 people
- Sponsor
- Medical University of Gdansk
Anxiety, Depression
Impact of Information Strategy Based on Booklet on Anxiety in Family in ICU
Anxiety and depression are symptoms frequently met in ICU patients and relatives. Risk factors are known: disease severity, age, gender. Another risk factor is lack of information from the medical staff and nurses.
- Conditions
- Anxiety, Depression, Post-traumatic Stress Disorders
- Trial name
- FAMILLE (NCT01365377)
- Testing
- booklet deliverance and use in the process of daily information
- Where
- France
- Volunteers
- 180 people
- Sponsor
- Groupe Hospitalier Pitie-Salpetriere
Traumatic Brain Injury, Ventilator Associated Pneumonia
Effect of E-BAL on Severity of VAP Assessed Through CPIS on the Patients of Traumatic Brain Injury in Neurocritical Care, Also Effect on Days of Ventilation and ICU Stay.
Severe traumatic brain injury (STBI) is a leading cause of disability, mortality, and economic burden worldwide. The impact of severe traumatic brain injury (STBI) on the economy of developing countries like Pakistan is…
- Trial name
- NCT04977843
- Testing
- EARLY BRONCHOALVEOLAR LAVAGE
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Jinnah Hospital
Non Traumatic Acute Brain Injury
Non Traumatic Neuro-Vascular Diseases Critical Complications : a Prospective Cohort Study
The purpose of this observational epidemiological study is to investigate the management and the complications associated with Non Traumatic Neuro-Vascular Diseases.
- Trial name
- ATLANREA (NCT02714387)
- Testing
- Collection of medical data
- Where
- 6 sites in France
- Volunteers
- 5,000 people
- Sponsor
- Nantes University Hospital
Burns
Study on the Infection Risk of Long Dwell Period Catheters in High Risk Intensive Care Unit (ICU) Patients
This is an evaluation of the use of silver impregnated catheters in burn patients to reduce catheter colonisation compared to the standard central venous catheter without antiseptic activity.
- Trial name
- NCT00136097
- Testing
- Placement of a silver impregnated central venous catheter
- Where
- Belgium
- Volunteers
- 142 people
- Sponsor
- University Hospital, Ghent
Traumatic Brain Injury
Erythropoietin in Traumatic Brain Injury (EPO-TBI)
This study seeks to determine if erythropoietin alpha (EPO) administered to adult critical care patients with moderate or severe traumatic brain injury improves neurological function assessed at six months after injury.
- Trial name
- EPO-TBI (NCT00987454)
- Testing
- Epoetin Alfa, Sodium Chloride 0.9%
- Where
- 28 sites in Australia, Finland and 5 more
- Volunteers
- 606 people
- Sponsor
- Australian and New Zealand Intensive Care Research Centre