Clinical trials: Traumatic Injuries
Chronic Traumatic Encephalopathy
18F-AV-1451 and Florbetapir F 18 PET (Positron Emission Tomography) Imaging in Subjects at Risk for Chronic Traumatic Encephalopathy
This study will explore the use of flortaucipir as a biomarker for chronic traumatic encephalopathy (CTE) and examine the relationship between clinical presentation and tau deposition.
- Trial name
- NCT02079766
- Testing
- florbetapir F 18, Flortaucipir F18
- Where
- 2 sites in United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Avid Radiopharmaceuticals
Shoulder Dislocation
Early arthroscoPic Stabilization veRsus rehabilitatiOn of the Shoulder in Adolescents With a trauMatic First-time Anterior Shoulder Dislocation ePisode
Each year within Canada and the US, more than 30,000 children and adolescents will have an injury to their shoulder resulting in a shoulder dislocation.
- Trial name
- PROMPT (NCT04887337)
- Testing
- Arthroscopic stabilization, Rehabilitation including a period of immobilization followed by physical therapy
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- McMaster University
Traumatic Brain Injury, Acquired Brain Injury
Venous and Cerebral Glucose Microdialysis in Neurocritical Care: Validation & Correlation
This study evaluates the validity of an intravascular continuous glucose monitoring microdialysis probe, and compares the values to routinely inserted cerebral glucose microdialysis to evaluate the hypothesised relationship…
- Conditions
- Traumatic Brain Injury, Acquired Brain Injury, Intracerebral Hemorrhage, Subarachnoid Hemorrhage
- Trial name
- NCT03246607
- Testing
- MicroEye & ContinuMon
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Dr Andrew Stevens
Traumatic Injury, Technology
Evaluation of Trauma Center-Based Intervention for Adolescent Traumatic Injury Survivors
Pediatric traumatic injury (i.e., injury of sudden onset and severity requiring immediate attention) is the leading cause of death and morbidity among US adolescents and are associated with mental health and health risk outcomes…
- Conditions
- Traumatic Injury, Technology, Posttraumatic Stress Disorder, Adolescents
- Trial name
- NCT05086757
- Testing
- TRRP, Enhanced Usual Care
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Severe Trauma, General Anaesthesia
Association Between a Peri-traumatic Dissociation State and the Occurrence of Post-traumatic Stress Syndrome
Patients will be selected after studying clinical records.Patients who had general anesthesia due to an injury related to severe trauma within 6 to 12 months prior to inclusion will be included.
- Trial name
- DIStress-AG (NCT03930966)
- Testing
- PDEQ, PCL-5 and demographic survey
- Where
- France
- Volunteers
- 148 people
- Sponsor
- University Hospital, Brest
Concussion, Mild
Delivery of Digital Cognitive Behavioural Therapy Following Concussion
Concussion is common and patients can go on to suffer with a constellation of symptoms which impacts their functional outcome and quality of life.
- Trial name
- HEADON (NCT05069948)
- Testing
- HeadOn
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University of Edinburgh
Dental Trauma, Enamel Hypoplasia
Evaluation of Sequelae in Permanent Successors Following Traumatic Injuries to Primary Teeth
Retrospective data analysis of children with primary dental trauma and follow-up visual examination to find out the sequelae.
- Conditions
- Dental Trauma, Enamel Hypoplasia, Sequelae, Sequelae Successors
- Trial name
- NCT07134348
- Where
- Turkey (Türkiye)
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Zeynep Aslı GÜÇLÜ
Trauma
Psycho-education Program BLAME-LESS and It's Effect on Traumarelated Shame and Guilt
The primary objective of the BLAME-LESS study is to examine the effectiveness of an online psychoeducation program in reducing trauma-related feelings of shame and guilt in adolescents who experienced sexual or physical abuse .
- Trial name
- BLAME-LESS (NCT05987735)
- Testing
- BLAME-LESS
- Where
- Netherlands
- Volunteers
- 34 people
- Sponsor
- Karakter Kinder- en Jeugdpsychiatrie
Perinatal Depression
Perinatal Mental Health for Refugee Women
Since February 24th, 2022, the beginning of Russia's aggression against Ukraine, more than 80,000 women were expected to give birth.
- Trial name
- PMH-RW (NCT05654987)
- Where
- 2 sites in Poland, Ukraine
- Volunteers
- 600 people
- Sponsor
- Universidad Nacional de Educación a Distancia
Abdominal Injury, Pelvic Injury
Effects of a Contextual Decision-making Materials on Junior Nurses in Traumatic Learning Performance
Trauma leading to severe bleeding is one of the reasons for the high mortality rate in trauma patients, resulting in multiple and complex injuries from various accidental mechanisms.
- Trial name
- NCT06574607
- Testing
- Interactive Educational Material for Decision-Making, Interactive Educational Material
- Where
- Taiwan
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Finger Injuries, Amputation, Traumatic
A Comparison of the Outcomes of Distal Fingertip Amputations Treated With Either Artificial (Xeroform) or Biological Dressings
This is a prospective study looking to evaluate whether the treatment outcomes for patients who sustain a distal fingertip amputation are improved or no different when using biological dressings versus artificial dressings.
- Trial name
- NCT03968835
- Testing
- Bacitracin, Skin Graft
- Where
- United States
- Sponsor
- NYU Langone Health
Post-Traumatic Stress Disorder, Sleep Disturbance
Aerobic Exercise Intervention for PTSD Symptoms and Sleep Quality After Earthquake
This randomized controlled trial aims to examine the effects of a moderate-intensity aerobic exercise program on post-traumatic stress disorder (PTSD) symptoms and sleep quality among earthquake survivors living in temporary…
- Trial name
- EX-PTSD (NCT07474259)
- Testing
- Moderate-Intensity Aerobic Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Malatya Turgut Ozal University
Traumatic Brain Injury
Prehospital Tranexamic Acid Use for Traumatic Brain Injury
Primary aim: To determine the efficacy of two dosing regimens of TXA initiated in the prehospital setting in patients with moderate to severe TBI (GCS score ≤12).
- Trial name
- TXA (NCT01990768)
- Testing
- 1 gram Tranexamic Acid (TXA), 2 grams TXA, 0.9% Sodium Chloride injectable
- Where
- 12 sites in United States, Canada
- Volunteers
- 967 people
- Sponsor
- University of Washington
Hemorrhagic Shock, Traumatic Brain Injury
Hypertonic Modulation of Inflammation Following Injury
This project seeks to determine the effect of prehospital resuscitation with hypertonic saline vs. conventional crystalloids on the inflammatory response after injury.
- Trial name
- NCT00750997
- Testing
- hypertonic saline
- Where
- 2 sites in United States, Canada
- Volunteers
- 119 people
- Sponsor
- University of Washington
Concussion
Vascular Assessment of Regulation Index Arrays Registry
The objective of this patient registry is to collect and analyze physiological data associated with baseline and brain injury identified in standard clinical practice (Normal Values, Recovery Curves, Correlation between Symptoms…
- Trial name
- VARIA (NCT02435082)
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- NeuroChaos Solutions, Inc.
Post Traumatic Stress Disorder (PTSD)
TMS for PTSD in Youth
The purpose of this study is to test whether transcranial magnetic stimulation, or TMS, is an acceptable and helpful treatment for ongoing symptoms of posttraumatic stress syndrome disorder (PTSD) in 12-20 year olds.
- Trial name
- NCT07401225
- Testing
- MagPro R30 with robotic arm
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Insomnia, Traumatic Brain Injury
Non-Pharmacological Treatments for Insomnia in Chronic Traumatic Brain Injury
The purpose of this clinical trial is to assess the relative efficacy of two non-pharmacological interventions for insomnia in Veterans suffering from chronic mild traumatic brain injury (mTBI).
- Trial name
- NCT03261674
- Testing
- CBT-I, ABT-I
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- VA Office of Research and Development
Stress Disorders, Post-Traumatic
Evaluation of an Intensive Inpatient Psychotherapy Treatment for Severely and Early Traumatized Children (MOSES)
Evaluation of longitudinal treatment effects applying an intensive psychotherapeutic intervention for inpatients (age of participants: 6-13 years) with a multi-method-approach to address the complex nature of severe childhood…
- Trial name
- MOSES (NCT03894774)
- Testing
- Intensive in-patient psychotherapy treatment, Treatment as usual
- Where
- Germany
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- LMU Klinikum
Head Injury, Face
Craneofacial Injuries in Rink Hockey Athletes
To collect the number of injuries that affect the face and head in rink hockey athletes prospectively during a regular season.
- Conditions
- Head Injury, Face, Concussion, Brain
- Trial name
- NCT05400551
- Where
- 2 sites in Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Oviedo
Anterior Cruciate Ligament Injuries, Concussion, Brain
Making Football Safer for Women: Implementing an Injury Prevention Program
The aim of this study is to determine how we can best support coaches to implement an injury prevention (IP) program (Prep-to-Play) in female community Australian Football.
- Conditions
- Anterior Cruciate Ligament Injuries, Concussion, Brain, Musculoskeletal Injury
- Trial name
- Prep-to-Play (NCT04856241)
- Testing
- Coaching, Peer support, Educational materials
- Where
- Australia
- Volunteers
- 2,600 people, healthy volunteers welcome
- Sponsor
- La Trobe University
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