Clinical trials: Trigeminal Neuralgia
Neurotrophic Corneal Ulcer, Neurotrophic Keratitis
Corneal Neurotization as a Treatment for Neurotrophic Keratopathy
The purpose of this study is to assess the efficacy of sural nerve transfer and cadaveric nerve graft to re-establish corneal sensation in patients with neurotrophic keratopathy.
- Conditions
- Neurotrophic Corneal Ulcer, Neurotrophic Keratitis, Cranial Nerve V Diseases
- Trial name
- NCT05809245
- Testing
- Corneal neurotization
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Stanford University
Inferior Alveolar Nerve Injuries
Does Low-level Laser Therapy Protocol Affect the Efficacy of Treatment of Inferior Alveolar Nerve Injury After Maxillofacial Surgery
Dear Patient, Dear Parent / Guardian; This consent form has been prepared to enlighten you about the nature of the diagnosis and treatment methods that have been explained to you/patient and will be applied, the expected benefits…
- Trial name
- NCT06893497
- Testing
- Low Level Laser Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Karadeniz Technical University
Trigeminal Neuralgia
Prognosis of Trigeminal Neuralgia When Enrolled in a Multidisciplinary Management Program
Background: Prognosis of medically treated trigeminal neuralgia patients is assumed to be poor, but the evidence is lacking. Thus, prospective real-life studies of medical management of trigeminal neuralgia are warranted.
- Trial name
- NCT03838393
- Testing
- multidisciplinary management
- Volunteers
- 186 people
- Sponsor
- Danish Headache Center
Trigeminal Neuralgia
Comparing Clinical Benefits of Gamma Knife and Microvascular Decompression for Trigeminal Neuralgia
Clinical randomized study to compare the clinical effectiveness between two modalities of treatment of trigeminal neuralgia namely gamma knife radio surgery and microvascular decompression
- Trial name
- NCT03991039
- Testing
- Gamma knife
- Volunteers
- 84 people
- Sponsor
- University of Baghdad
Nerve Injury, Orofacial Pain
Post-traumatic Neuropathy of the Trigeminal Nerve
This is retrospective research mainly aims to determine the patterns of symptoms, clinical and radiological findings and outcomes in patients with trigeminal neuropathy following trauma or iatrogenic damage and how this…
- Conditions
- Nerve Injury, Orofacial Pain, Trigeminal Nerve Injuries, Trigeminal Neuropathy
- Trial name
- NCT04612855
- Testing
- Groupwise comparison of primary and secondary outcomes
- Where
- Belgium
- Volunteers
- 1,333 people
- Sponsor
- KU Leuven
Trigeminal Neuralgia
Comparision Efficacy of Carbamazepine & Oxcarbazepine in the Treatment of Trigeminal Neuralgia- a Randomised Clinical Trial
Trigeminal neuralgia is a neuropathic facial pain condition, characterized by unilateral paroxysmal pain which can be described as stabbing or electric shock like, in the distribution of one or more divisions of trigeminal nerve…
- Trial name
- NCT04996199
- Testing
- Oxcarbazepine, Carbamazepine
- Where
- 2 sites in India
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Neoplasms, Arteriovenous Malformation of Central Nervous System
RSSearch Patient Registry-Long Term Study of Use of SRS/SBRT
The RSSearch® Registry is an international multi-year database designed to track SRS/SBRT (Stereotactic Radiosurgery/Stereotactic Body Radiation Therapy) utilization, treatment practices and outcomes to help determine, over time…
- Conditions
- Neoplasms, Arteriovenous Malformation of Central Nervous System, Trigeminal Neuralgia
- Trial name
- NCT01885299
- Testing
- SRS/SBRT
- Where
- 13 sites in United States
- Volunteers
- 50,000 people
- Sponsor
- The Radiosurgery Society
Malaria
A Community Setting Study of Malaria After Systematic Treatment of Symptomatic Carriers of P. Falciparum With COA566 (Coartem®)
This study assessed the impact of the systematic detection by Rapid Diagnostic Test (RDT) and treatment of asymptomatic carriers of malaria parasites (P.
- Trial name
- NCT01256658
- Testing
- COA566
- Where
- 3 sites in Burkina Faso
- Volunteers
- 14,075 people
- Sponsor
- Novartis
Surgery, Brain Tumor
Neurosurgical Transitional Care Programme
Readmissions increasingly serve as a metric of hospital performance, inviting quality improvement initiatives in both medicine and surgery.
- Conditions
- Surgery, Brain Tumor, Brain Tumor, Recurrent, Brain Pathology
- Trial name
- TCP (NCT03593330)
- Testing
- Transitional Care Programme
- Where
- United Kingdom
- Volunteers
- 242 people
- Sponsor
- Barts & The London NHS Trust
Trigeminal Neuralgia
Efficacy and Safety Study of Lamotrigine to Treat Trigeminal Neuralgia
The purpose of this study was to determine the efficacy and safety of lamotrigine in patients with trigeminal neuralgia (TGN).
- Trial name
- NCT00913107
- Testing
- Lamictal®, Tegretol®
- Where
- 2 sites in Malaysia
- Volunteers
- 21 people
- Sponsor
- University of Malaya
Postoperative Infections, Mandibular Nerve Injuries
Surgeons' Prediction of Dental Surgery Complications and the Influence of Patient Characteristics: Development of an AI Model
The goal of this observational study is to learn how to better predict and prevent intra- and postoperative complications in oral surgery in adult patients referred for oral surgical procedures.
- Conditions
- Postoperative Infections, Mandibular Nerve Injuries, Alveolar Osteitis, Complication
- Trial name
- NCT07461324
- Where
- 2 sites in Denmark
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Impacted Third Molar Tooth, Tooth Extraction Status Nos
Clinical Validation of a Novel Classification for Predicting Surgical Complexity in Mandibular Wisdom Teeth Surgery
The study evaluates and validates a new classification proposed by Juodzbalys and Daugela in 2013 predicting the complexity of impacted mandibular third molars surgical extraction, comparing it with other two, scientifically…
- Trial name
- NCT02519426
- Testing
- Mandibular third molar surgery
- Where
- 2 sites in Italy, Lithuania
- Volunteers
- 110 people
- Sponsor
- Lithuanian University of Health Sciences
Trigeminal Neuralgia
Regional Anesthesia in Refractory Trigeminal Neuralgia: 21 Cases Reported to the Limoges University Hospital
Trigeminal neuralgia is defined according to the third edition of the International Classification of Headache Disorders (ICHD-3) criteria. Chronic pain can have a major impact on the quality of life.
- Trial name
- TRINEB ONE (NCT03669744)
- Testing
- telephone survey
- Where
- France
- Volunteers
- 21 people
- Sponsor
- University Hospital, Limoges
Facial Pain
MRI & QST Analysis in Trigeminal Neuralgia and Persistent Idiopathic Facial Pain
Patients with a definite diagnosis of classical TGN and PIFP will undergo a structured clinical questionnaire and a trigeminal sensory profile using the quantitative sensory testing.
- Trial name
- NCT05147454
- Testing
- Quantitative Sensory Testing
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Walton Centre NHS Foundation Trust
Surgical Complication, Paresthesia
Trial of Bilateral Sagittal Split Osteotomy Induced Paresthesia Using Ultrasonic vs. Reciprocating Saw Instrumentation
The aim of this prospective study is to analyze the postoperative paresthesias experienced in patients who undergo bilateral sagittal split osteotomies (BSSO) using an ultrasonic saw, versus a reciprocating saw.
- Conditions
- Surgical Complication, Paresthesia, Fracture, Nerve Injury
- Trial name
- NCT05205616
- Testing
- Sonopet ultrasonic saw, Reciprocating saw
- Where
- 2 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Trigeminal Neuralgia
Comparative Study inTreatment of Trigeminal Neuralgia
This study aims to evaluate the results of percutaneous radiofrequency rhizotomy and the effectiveness of microvascular decompression for the treatment of trigeminal neuralgia and Comparing between them according the different…
- Trial name
- NCT04801407
- Testing
- percutaneous radiofrequency trigeminal rhizotomy, Microvascular decompression of the trigeminal nerve
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Sohag University
Trigeminal Neuralgia, Refractory Pain
Fluoroscopic-Guided Bipolar Versus Monopolar Pulsed Radiofrequency for Refractory Trigeminal Neuralgia
A prospective exploratory study aiming at comparing pulsed bipolar versus pulsed unipolar radiofrequency ablation in patients with medically refractory trigeminal neuralgia.
- Trial name
- NCT06779578
- Testing
- Bipolar pulsed radiofrequency, Mopolar pulsed radiofrequency
- Where
- 2 sites in Egypt
- Volunteers
- 20 people
- Sponsor
- Alexandria University
Facial Neuralgia, Pain
Studies of Dextromethorphan and Topiramate to Treat Oral and Facial Pain
This study will evaluate the safety and effectiveness of two drugs-dextromethorphan and topiramate-in treating orofacial (mouth and face) pain.
- Conditions
- Facial Neuralgia, Pain, Trigeminal Neuralgia
- Trial name
- NCT00001725
- Testing
- Dextromethorphan
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Trigeminal Neuralgia
Research Study to Test Safety and Effectiveness of Investigational Drug in Patients With Trigeminal Neuralgia
This research study will look at the safety (e.g., the occurrence of side effects) and efficacy (how well the drug works in reducing trigeminal neuralgia attacks) of a drug called lamotrigine in adults with trigeminal neuralgia.
- Trial name
- NCT00203229
- Testing
- lamotrigine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Thomas Jefferson University
Inferior Alveolar Nerve Injuries, Impacted Third Molar Tooth
The Impact of 3D-CBCT Imaging on Nerve Injuries During Wisdom Tooth Surgery
The investigators aim to investigate if the additional information available from a 3D scan of the wisdom tooth can reduce the risk of nerve injury during wisdom tooth surgery compared to conventional 2D images.
- Trial name
- IMPACTION (NCT06261853)
- Testing
- 3D-CBCT, 2D-OPG
- Where
- 2 sites in United Kingdom
- Volunteers
- 1,292 people
- Sponsor
- University of Aberdeen