Clinical trials: Type1diabetes
Type1diabetes
Pilot Study to Explore the Efficacy of DAPAglifozin as add-on to Closed-loop Control in Patients With Type 1 Diabetes
Dapagliflozin has a unique mechanism of action that does not directly affect either insulin resistance or insulin secretion, but rather improves glycemia by reduction of glucose re-absorption from proximal renal tubules.
- Trial name
- DapaDream (NCT02987738)
- Testing
- Dapagliflozin
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Kinderkrankenhaus auf der Bult
Type1diabetes
Development of Predictive Biomarkers
Investigators aim to further the understanding of the various factors that govern the progression of beta-cell death in individuals recently diagnosed with Type 1 diabetes (T1D).
- Trial name
- NCT03423862
- Testing
- Mixed Meal Tolerance Test
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Medical College of Wisconsin
Type1diabetes, Type1 Diabetes Mellitus
Type 1 Teamwork: A Tool for Parents of Adolescents With Type 1 Diabetes
Type 1 Diabetes (T1DM) is a common chronic illness in children which presents difficult and often stressful management concerns for parents.
- Trial name
- Type1 (NCT04073914)
- Testing
- Type 1 Teamwork Program
- Where
- 2 sites in United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Carelon Research
type1diabetes
Empagliflozin in Adolescent Diabetes
Empagliflozin, an inhibitor of the sodium glucose co-transporter 2 (SGLT2), reduces post-prandial glucose levels in adults with both type 2 and type 1 diabetes and importantly reduces both cardiovascular and renal complications…
- Trial name
- NCT04917692
- Testing
- Empagliflozin
- Where
- United States
- Sponsor
- Ohio State University
Small for Gestational Age at Delivery, Gestational Diabetes
The CanDo (Canadian Donor Milk) Trial
The goal of this clinical trial is to learn about the impact of donor milk vs formula supplementation on human milk feeding and the health outcomes of infants who require supplementation in well-baby units.
- Conditions
- Small for Gestational Age at Delivery, Gestational Diabetes, type1diabetes, Type2diabetes
- Trial name
- NCT06315127
- Testing
- Human donor milk, Formula
- Where
- 3 sites in Canada
- Volunteers
- 112 people
- Sponsor
- Mount Sinai Hospital, Canada
Type1diabetes
Teamwork, Targets, Technology, and Tight Control in Newly Diagnosed Pediatric T1D - 4T Study
The 4T program encompasses: Teamwork, Targets, Technology, and Tight Range. These methods will help patients better manage their condition of Type 1 Diabetes with improved patient-reported outcomes.
- Trial name
- NCT04336969
- Testing
- 4T Education and Care
- Where
- United States
- Volunteers
- 316 people
- Sponsor
- Stanford University
Non-Nutritive Sweetener, Type 1 Diabetes
Cardiometabolic Effects of Non-Nutritive Sweeteners (NNS) in Type 1 Diabetes (T1D)
This project will apply a novel non-nutritive sweetener (NNS) dietary assessment tool with measurement of circulating NNS levels in a pediatric population, allowing correlation of NNS exposure to clinically meaningful…
- Conditions
- Non-Nutritive Sweetener, Type 1 Diabetes, type1diabetes, Type 1 Diabetes Mellitus
- Trial name
- NCT07434544
- Testing
- Cherry Sports Drink
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical College of Wisconsin
Type1diabetes
Iterative Beta Testing of Videos for the DIPPer Academy
The purpose of this research is to develop DIPPer Academy, a parent-focused, mobile health (mHealth) behavioral intervention to promote glycemic control in young children.
- Trial name
- DIPPer Academy (NCT03385265)
- Testing
- DIPPer Academy, Standard of Care
- Where
- 2 sites in United States
- Volunteers
- 62 people
- Sponsor
- University of Kansas Medical Center
type1diabetes, Diabetes Distress
Expectations of People With Type 1 Diabetes About Voice-based Interventions to Support Diabetes Distress Management
This study explores the perspectives and needs of people dealing with type 1 diabetes or their carers to co-design a voice-based digital health intervention for supporting diabetes distress management.
- Trial name
- PSYVOICE (NCT05517772)
- Where
- Luxembourg
- Volunteers
- 12 people
- Sponsor
- Luxembourg Institute of Health
Type1diabetes
School Readiness in Children with Type 1 Diabetes
It is known that motor and sensory functions are affected in children with type 1 diabetes (T1DM).This may cause children to have restrictions in their daily lives and decrease their participation in activities.Motor and sensory…
- Trial name
- NCT06673251
- Testing
- motor and sensory assessments, surveys
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- arife akbulut
type1diabetes
Motivational Interviewing to Improve Self Management in Youth With Type 1 Diabetes
A brief, nurse-led educational intervention using motivational interviewing substantially improved general and disease-specific self-management skills in youth with type 1 diabetes.
- Trial name
- NCT04798937
- Testing
- Motivational interviewing
- Where
- Tunisia
- Volunteers
- 66 people
- Sponsor
- Université de Sousse
Type1diabetes
HIT in People With Type 1 Diabetes
Few people with type 1 diabetes achieve exercise guidelines and many programmes designed to increase physical activity have failed.
- Trial name
- NCT03545841
- Testing
- HIT, MICT
- Where
- United Kingdom
- Volunteers
- 14 people
- Sponsor
- Liverpool John Moores University
Type1diabetes
Personalized Automated Determination of Insulin Pump Setting for Subjects With Type 1 Diabetes Switching From MDI to Pump Therapy and Vice Versa- Safety and Efficacy Feasibility Study
The "MD-Logic Switch Advisor" is a software product that is designed to assist in insulin dosage decision making and has two components: A.
- Trial name
- NCT03574558
- Testing
- MD-Logic Switch Advisor
- Where
- Israel
- Volunteers
- 28 people
- Sponsor
- Rabin Medical Center
Type1diabetes
Self Efficacy Levels, Attachment Style and Resiliency of Youth With Type 1 Diabetes
This project will assess self-efficacy levels(SE) ,resiliency and attachment style of adolescent with type 1 diabetes and their caregivers.SE and attachment style of patients and parents will be compared with each other as well…
- Trial name
- NCT04172077
- Where
- Canada
- Volunteers
- 170 people
- Sponsor
- The Hospital for Sick Children
Type1diabetes
Real World Evaluation of Advisor Pro in Clinical Practice
To assess the integration of the DreaMed Advisor Pro tool into a real-world clinical practice using both in person and virtual visits to assess benefits in glycemia, as measured by the glucose management indicator and other…
- Trial name
- NCT04904718
- Testing
- DreaMed Advisor Pro
- Sponsor
- Yale University
Type1diabetes
Petit Cactus Study
The goal of this trial is to test a newly developed carbohydrate counting mobile application (named Petit Cactus) with photo recognition, for people with type 1 diabetes. To evaluate Petit Cactus, our objectives are: 1.
- Trial name
- NCT07380802
- Testing
- Petit Cactus
- Where
- Canada
- Volunteers
- 73 people
- Sponsor
- McGill University
Type1diabetes, Sleep
Sleep Patterns and Chronotype in Children With and Without Type 1 Diabetes
Type 1 diabetes (T1D) is one of the most common chronic childhood diseases. Recent studies have highlighted the strong association between type 1 diabetes and sleep health problems.
- Conditions
- Type1diabetes, Sleep, Chronotype
- Trial name
- NCT06318611
- Testing
- sleep, chronotype
- Where
- Turkey (Türkiye)
- Volunteers
- 168 people
- Sponsor
- Koç University
Type1diabetes
Screening for Islet Autoantibodies in the Israeli Paediatric General Population for Detection of Pre-symptomatic Type-1 Diabetes Mellitus
A national screening program for children aged 9 months-5 years that will be tested for the presence of islet autoantibodies.Up to 50,000 Children will be screened by their primary care physician all over Israel.
- Trial name
- ADIR (NCT04834518)
- Where
- 7 sites in Israel
- Volunteers
- 50,000 people
- Sponsor
- Rabin Medical Center
Type1diabetes
Defining the Role of Management Factors in Outcome Disparity in Pediatric T1D
Type 1 diabetes (T1D), is associated with considerable risk of morbidity and mortality due to chronic hyperglycemia. Despite innovations in management, pediatric patients of African ancestry (AA) have been found to have…
- Trial name
- NCT04614623
- Testing
- AHCL pump, Video conferencing Application
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Children's Hospital New Orleans, LA
Type1diabetes
Diluted Insulin in Young Children: Bigger Volumes for Smaller Patients
The aim of this study is to compare the pharmacokinetic (PK) profile of diluted insulin aspart (U25) with undiluted insulin aspart (U100) in school-aged children and adolescents with type 1 diabetes (T1D) utilizing the euglycemic…
- Trial name
- NCT03666065
- Testing
- Aspart insulin
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Yale University