Clinical trials: UC - Ulcerative Colitis
Inflammatory Bowel Diseases
Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cell Intravenous Infusion for Crohn's Disease or Ulcerative Colitis
This trial will study the safety and efficacy of intravenous infusion of cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cells for the treatment of Crohn's Disease or Ulcerative Colitis
- Trial name
- NCT05003947
- Testing
- cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cells
- Where
- 2 sites in United States, Greece
- Volunteers
- 15 people
- Sponsor
- The Foundation for Orthopaedics and Regenerative Medicine
Inflammatory Bowel Diseases, Crohn Disease
Exploration of the Activity of DNA Located Outside of Cellular Nucleus to Amplify Inflammation in Inflammatory Bowel Disease in Children Through Biological Pathway Cyclic GMP-AMP Synthase (cGAS) - Stimulator of Interferon Genes (STING)
Frequency of Inflammatory Bowel Diseases in children (IBD)-Crohn's disease (CD), Ulcerative colitis (UC) is constantly increasing.
- Conditions
- Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis
- Trial name
- ROXANE (NCT05916274)
- Testing
- Blood and fecal samples, Coolonic biopsies
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Inflammatory Bowel Disease, Crohn's Disease
Monroe County Inflammatory Bowel Disease (IBD) Registry
This phase is to register all subjects in Monroe County, New York with Inflammatory Bowel Disease (IBD) not already included to update the database for years 1990-2003.
- Conditions
- Inflammatory Bowel Disease, Crohn's Disease, Ulcerative Colitis
- Trial name
- NCT01032525
- Volunteers
- 720 people
- Sponsor
- University of Rochester
Ulcerative Colitis
Safety and Compliance of Taking Mesalamine Once a Day in Pediatric Patients
To determine whether once a day administration of Mesalamine is at least as safe and efficacious and administration of multiple doses a day in preventing clinical relapse of ulcerative colitis in children and adolescence.
- Trial name
- NCT00349388
- Testing
- Asacol
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Annette Langseder
Crohn's Disease, Ulcerative Colitis
Improving Medication Adherence in Pediatric Inflammatory Bowel Disease
The purpose of the study is to test an online behavioral intervention to improve medication adherence in children diagnosed with Inflammatory Bowel Disease.
- Conditions
- Crohn's Disease, Ulcerative Colitis, Indeterminate Colitis, Inflammatory Bowel Disease
- Trial name
- TEAM (NCT01536509)
- Testing
- Telehealth Behavioral Treatment (TBT), Education Only (EO)
- Where
- 9 sites in United States
- Volunteers
- 140 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Inflammatory Bowel Diseases, Ulcerative Colitis
Serum Bovine Immunoglobulin (SBI) in Children and Young Adults With Inflammatory Bowel Disease (IBD)
This is a randomized, double-blind placebo controlled study to assess for safety, tolerability and nutritional impact of oral serum bovine immunoglobulin (SBI) on pediatric patients and young adults with inflammatory bowel…
- Conditions
- Inflammatory Bowel Diseases, Ulcerative Colitis, Crohn Disease
- Trial name
- NCT04223518
- Testing
- Serum bovine immunoglobulin
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Monisha Hitesh Shah
Ankylosing Spondylitis (AS) / Radiographic Axial SpA (r-axSpA), Non-radiographic Axial Spondyloarthritis (Nr-axSpA)
Chinese Spondyloarthritis Inception Cohort (CESPIC)
The Chinese Spondyloarthritis Inception cohort (CESPIC) was started 2000 as a prospective, longitudinal, multicentre, nationwide study in China on patients with early SpA including ankylosing spondylitis (AS, also known as…
- Conditions
- Ankylosing Spondylitis (AS) / Radiographic Axial SpA (r-axSpA), Non-radiographic Axial Spondyloarthritis (Nr-axSpA), Axial Psoriatic Arthritis (axPsA), Acute Anterior Uveitis (AAU)
- Trial name
- CESPIC (NCT05960864)
- Testing
- Celecoxib
- Volunteers
- 1,000 people
- Sponsor
- Southwest Hospital, China
Inflammatory Bowel Disease, Uterine Cervical Dysplasia
Immune Response to the Human Papillomavirus Vaccine in Young Women With Inflammatory Bowel Disease
The Gardasil vaccine, a vaccine targeted towards the human papillomavirus (HPV), has been shown to prevent the transmission of several strains of HPV in young women.
- Trial name
- NCT01034358
- Testing
- Human Papillomavirus Vaccine
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Mayo Clinic
Inflammatory Bowel Diseases
IBDoc® Canadian User Performance Evaluation
The objective of the IBDoc® user performance evaluation is to demonstrate the ease-of-use of the IBDoc® calprotectin home test to allow patients with inflammatory bowel disease (IBD) to independently and correctly determine…
- Trial name
- NCT03408249
- Testing
- IBDoc calprotectin test, questionnaire
- Where
- 3 sites in Canada
- Volunteers
- 61 people
- Sponsor
- Bühlmann Laboratories AG
Crohn Disease, Ulcerative Colitis
Clinical Study of Targeting CD7 CAR-T Cells in the Treatment of Autoimmune Diseases
A Clinical Study on the Safety and Effectiveness of Targeting CD7 Chimeric Antigen Receptor T Cells in the Treatment of Autoimmune Diseases
- Conditions
- Crohn Disease, Ulcerative Colitis, Dermatomyositis, Still Disease
- Trial name
- NCT05239702
- Testing
- CD7 CAR T-cells
- Where
- China
- Volunteers
- 75 people
- Sponsor
- Zhejiang University
IBD (Inflammatory Bowel Disease), IBS (Irritable Bowel Syndrome)
Specimen and Data Collection for a Novel Biomarker Combination for the Differential Diagnosis of Inflammatory Bowel Disease and Irritable Bowel Syndrome.
This study will evaluate how well the a new stool test can distinguish inflammatory bowel disease (IBD) from non-IBD conditions compared with standard calprotectin testing and colonoscopy findings.
- Conditions
- IBD (Inflammatory Bowel Disease), IBS (Irritable Bowel Syndrome), Gastrointestinal Symptoms
- Trial name
- COMBI (NCT07471490)
- Where
- 2 sites in United States, Italy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- DiaSorin Inc.
Ulcerative Colitis
A Study of Ozanimod in Pregnant Women With Ulcerative Colitis and Their Offspring
The purpose of this study is to evaluate association between ozanimod exposure during pregnancy and subsequent maternal, fetal, and infant outcomes.
- Trial name
- NCT05953402
- Where
- United States
- Volunteers
- 1,182 people
- Sponsor
- Bristol-Myers Squibb
Ulcerative Colitis, Crohn's Disease
Development of 'Emma'--a Pediatric IBD Quiz
We would like to collaborate and further develop an ipad-based, interactive quiz game 'Emma'; to identify gaps in knowledge of inflammatory bowel disease in pediatric patients. These gaps can be used to improve patient education.
- Conditions
- Ulcerative Colitis, Crohn's Disease, Inflammatory Bowel Disease
- Trial name
- NCT02065089
- Testing
- playing the ipad quiz game
- Where
- 2 sites in United States
- Volunteers
- 116 people
- Sponsor
- Mayo Clinic
Ulcerative Colitis
Retarded Phosphatidylcholine Versus Mesalazin in Remission of Ulcerative Colitis.
The purpose of this study is to evaluate if retarded phosphatidylcholine is as effective as mesalazin in preventing an acute episode in ulcerative colitis.
- Trial name
- NCT00259571
- Testing
- retarded release phosphatidylcholine
- Where
- Germany
- Sponsor
- Heidelberg University
Ulcerative Colitis, Ulcerative Colitis Chronic
A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)
The main purpose of this study is to evaluate the long-term efficacy of mirikizumab in pediatric participants with ulcerative colitis (UC) or Crohn's disease (CD).
- Conditions
- Ulcerative Colitis, Ulcerative Colitis Chronic, Inflammatory Bowel Diseases, Crohn's Disease
- Trial name
- SHINE-ON (NCT04844606)
- Testing
- Mirikizumab
- Where
- 69 sites in United States, Austria and 14 more
- Volunteers
- 150 people
- Sponsor
- Eli Lilly and Company
Ulcerative Colitis (UC)
Impact of the Novel UC-TREAT Diet on the Gut Microbiome and Its Acceptability in Healthy Adults and Adults With Quiescent Ulcerative Colitis
This will be an open-label dietary intervention study recruiting both healthy adults (≥16y) and adults with quiescent Ulcerative Colitis (UC).
- Trial name
- UC-TREAT (NCT06998277)
- Testing
- Dietary therapy
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Crohn's Disease, Ulcerative Colitis
Expanded Access to Vedolizumab for Children and Teenagers With Ulcerative Colitis or Crohn's Disease in the USA
The expanded access program (EAP) allows people to gain access to an unlicensed treatment on compassionate grounds. This EAP provides children and teenagers with Ulcerative Colitis (UC) or Crohn's Disease (CD) who completed the…
- Trial name
- NCT06856135
- Testing
- Vedolizumab IV
- Where
- 3 sites in United States
- Sponsor
- Takeda
Ulcerative Colitis (UC), Acute Severe Ulcerative Colitis
Effectiveness and Safety of Upadacitinib for Acute Severe Ulcerative Colitis
The aim of this retrospective observational study is to investigate and compare the real-world effectiveness and safety of upadacitinib when used as first-line exposure versus rescue exposure in patients with acute severe…
- Conditions
- Ulcerative Colitis (UC), Acute Severe Ulcerative Colitis, Upadacitinib
- Trial name
- NCT07472309
- Testing
- Upadacitinib
- Where
- China
- Volunteers
- 81 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Crohn Disease, Ulcerative Colitis
Proactive Infliximab Optimization Using a Pharmacokinetic Dashboard Versus Standard of Care in Patients With Inflammatory Bowel Disease: The OPTIMIZE Trial
The OPTIMIZE Trial compares whether iDose dashboard-driven infliximab dosing (iDose-driven dosing) is more effective and safer than standard infliximab dosing for inducing and maintaining disease remission in inflammatory bowel…
- Conditions
- Crohn Disease, Ulcerative Colitis, Inflammatory Bowel Diseases
- Trial name
- NCT04835506
- Testing
- Infliximab
- Where
- 25 sites in United States, Canada
- Volunteers
- 124 people
- Sponsor
- Beth Israel Deaconess Medical Center
Ulcerative Colitis
Personalized Anti-Inflammatory Fibres in Ulcerative Colitis
The goal of this clinical trial is to determine the clinical effects of two different dietary fibre supplements, acacia gum (AG) and microcrystalline cellulose (MCC), in patients with ulcerative colitis.
- Trial name
- PAIF-UC (NCT06515210)
- Testing
- Acacia Gum, Microcrystalline Cellulose
- Where
- Canada
- Volunteers
- 69 people
- Sponsor
- University of Alberta