Clinical trials: Ulcer
Diabetes Mellitus, Foot Ulcer
Achilles Tendon Lengthening in Patients With Diabetes to Prevent Foot Ulcers
People with diabetes often develop severe skin problems (ulcers) on their feet. Sometimes these are treated with surgery and other times by temporarily immobilizing the foot in a cast.
- Conditions
- Diabetes Mellitus, Foot Ulcer, Peripheral Neuropathy
- Trial name
- NCT00006426
- Testing
- Achilles tendon-lengthening surgery
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Amputations, Diabetes
Clinical Trial of Footwear in Patients With Diabetes
A Seattle VA study indicated lower extremity ulcers preceded 84% of diabetic amputations. Nearly half of the events that ban the causal chain leading to ulcers and amputation were initiated by ill-fitting footwear.
- Conditions
- Amputations, Diabetes, Lower Extremity Ulcers
- Trial name
- NCT00032864
- Sponsor
- US Department of Veterans Affairs
Vaccinia
Evaluation and Treatment of Eye Complications of Vaccinia Vaccination
This study will evaluate patients with eye complications related to vaccination against smallpox to learn more about these conditions. Vaccinia vaccination has been used for more than 100 years for preventing smallpox.
- Trial name
- NCT00081835
- Testing
- NP-016 Vaccine Immune Globulin (IV-VIG)
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- National Eye Institute (NEI)
Ulcerative Colitis
ADAPT Adacolumn Pediatric Trial in Ulcerative Colitis
Children aged up to 18 years with moderately active Ulcerative Colitis (PUCAI:35-64) will receive one weekly Adacolumn® apheresis treatment over 5 consecutive weeks, followed by up to 3 optional Adacolumn® apheresis treatments…
- Trial name
- NCT00781638
- Testing
- Adacolumn®
- Volunteers
- 24 people
- Sponsor
- Otsuka Frankfurt Research Institute GmbH
Ulcerative Colitis, Inflammatory Bowel Diseases
Open Label Study to Assess Safety & Efficacy of QD for Induction of Remission in Pediatric Patients with UC
To date, there are no reports on the use of QD in pediatric patients with UC. There is a great need to increase the repertoire of anti-inflammatory interventions for remission induction, especially in children given the notorious…
- Trial name
- NCT06777706
- Testing
- QD (Qing Dai)
- Where
- 2 sites in Israel
- Volunteers
- 20 people
- Sponsor
- Shaare Zedek Medical Center
Gastrointestinal Hemorrhage, Ulcer
Gastroprotective Agent Compliance in Patients at Risk Suffering From a Gastrointestinal(GI) Ulcer
The purpose of this study is to assess gastroprotective agent compliance in patients at risk suffering from a gastrointestinal bleeding ulcer or a symptomatic ulcer with NSAID.
- Trial name
- NCT01215058
- Volunteers
- healthy volunteers welcome
- Sponsor
- AstraZeneca
Colitis, Ulcerative
COlonic Salvage by Therapeutic Appendectomy.
Rationale: The annual incidence of ulcerative colitis (UC) amounts to 6-8 new cases per 100.000. Patients are initially treated medically, and colitis refractory to medical management is treated surgically, mostly by means of an…
- Trial name
- COSTA (NCT03912714)
- Testing
- Laparoscopic appendectomy, Endoscopic appendix biopsies
- Where
- Netherlands
- Volunteers
- 123 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Helicobacter Infections, Gastritis
Tailored Treatment of H. Pylori Infection Based Polymorphisms of CYP2C19 and 23S rRNA of H. Pylori
The eradication rate of the standard H. pylori eradication therapy (such as the triple therapy with a proton pump inhibitor [PPI], amoxicillin and clarithromycin) depends on bacterial susceptibility to clarithromycin and…
- Conditions
- Helicobacter Infections, Gastritis, Gastric Ulcer, Duodenal Ulcer
- Trial name
- NCT00149084
- Testing
- Lansoprazole, clarithromycin, amoxicillin
- Where
- Japan
- Volunteers
- 296 people
- Sponsor
- Hamamatsu University
Ulcerative Colitis
Personalized Anti-Inflammatory Fibres in Ulcerative Colitis
The goal of this clinical trial is to determine the clinical effects of two different dietary fibre supplements, acacia gum (AG) and microcrystalline cellulose (MCC), in patients with ulcerative colitis.
- Trial name
- PAIF-UC (NCT06515210)
- Testing
- Acacia Gum, Microcrystalline Cellulose
- Where
- Canada
- Volunteers
- 69 people
- Sponsor
- University of Alberta
Other Preterm Infants
Invictus Medical, Medical Cranial Support Device (CSD) is a Device Safety Study in Infants at Risk of Head Ulcers.
While using the device as a cushion, the passive distribution of pressure over bony skull prominences of infants will protect against formation of pressure ulcers.
- Trial name
- INV-CS-001 (NCT02224859)
- Testing
- HCP will place the Invictus Cranial Support Device (CSD) on the patient, human intervention
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Invictus Medical, Inc.
Gastroesophageal Reflux Disease (GERD)
A Study of the Safety and Effectiveness of Rabeprazole for the Treatment of Gastroesophageal Reflux Disease (GERD) in Pediatric Patients
The purpose of the study is to access the effectiveness and safety of oral rabeprazole in the treatment of acid-related disorders in pediatric patients, focusing specifically on the manifestation of GERD (symptomatic and erosive…
- Trial name
- NCT00787891
- Testing
- rabeprazole
- Volunteers
- 127 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.