Clinical trials: Ulcerative Colitis (Disorder)
Colonoscopy, Inflammatory Bowel Disease (Crohn's Disease and Ulcerative Colitis)
Tissue Cytomegalovirus Viral Load and Associated Factors in Pediatric Patients Undergoing Colonoscopy
Introduction and Objectives Patients diagnosed with Inflammatory Bowel Disease (IBD) carry a significantly elevated risk for opportunistic infections and the reactivation of latent pathogens, most notably Cytomegalovirus (CMV).
- Conditions
- Colonoscopy, Inflammatory Bowel Disease (Crohn's Disease and Ulcerative Colitis), CMV
- Trial name
- NCT07419204
- Testing
- Colonoscopy after bowel cleansing
- Where
- Turkey (Türkiye)
- Volunteers
- 139 people
- Sponsor
- Gazi University
Inflammatory Bowel Diseases (IBD), Crohns Disease
Development and Validation of a New Paediatric Inflammatory Bowel Disease NUTrition Risk Score (PIBD-NUTS)
Children with inflammatory bowel disease (IBD) including both Crohn's disease (CD) and ulcerative colitis (UC) can be at high risk of developing malnutrition due to the nature of their condition.
- Conditions
- Inflammatory Bowel Diseases (IBD), Crohns Disease, Ulcerative Colitis (UC)
- Trial name
- PIBD-NUTS (NCT06723418)
- Testing
- Malnutriton Screening Tool (PYMS)
- Where
- 8 sites in Austria, Croatia and 4 more
- Volunteers
- 2,000 people
- Sponsor
- University of Glasgow
Ileal Pouch-Anal Anastomosis
Ileal Pouch-Anal Anastomosis Registry
Little is known about the factors that predispose patients to complications after an ileal pouch-anal anastomosis procedure (IPAA).
- Trial name
- IPAA (NCT01026480)
- Where
- United States
- Volunteers
- 936 people
- Sponsor
- Boston Medical Center
Inflammatory Bowel Diseases, Crohn Disease
Nutrition and Clinical Outcomes in IBD
The goal of this observational study is to demonstrate that nutritional status and body composition have an impact on clinical outcomes in inflammatory bowel disease (IBD). The main objectives are: 1.
- Conditions
- Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis, Malnutrition
- Trial name
- NUTRICO-IBD (NCT06550310)
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- Barts & The London NHS Trust
Inflammatory Bowel Diseases, Crohn's Disease
Transition of Inflammatory Bowel Disease (IBD) Patients From Pediatric to Adult Gastroenterologist (GI)
The purpose of this study is to determine if the program that has been made to ease the transition of care for adolescent patients with IBD from pediatric gastroenterology to adult gastroenterology is effective to reduce the risk…
- Conditions
- Inflammatory Bowel Diseases, Crohn's Disease, Ulcerative Colitis
- Trial name
- NCT00360022
- Testing
- Joint visits
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- Vanderbilt University Medical Center
Ulcerative Colitis, Pouchitis
Clotrimazole Enemas for Pouchitis in Children and Adults
Colectomy with creation of an ileal pouch (IPAA) is now the treatment of choice for patients with ulcerative colitis that is resistant to existing medical therapies.
- Conditions
- Ulcerative Colitis, Pouchitis, Ileitis, Inflammatory Bowel Disease
- Trial name
- CAPTURE (NCT00061282)
- Testing
- Clotrimazole
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Web
Gut Microbiome, Gastrointestinal Microbiome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder
- Trial name
- NCT04031469
- Testing
- There is no intervention in this study
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
Gastro-Intestinal Disorder, Crohn Disease
NAZA - Nottingham/Astra ZenecA Prospective IBD Cohort Study
The goal of this observational study is to learn about the comparisons of inflammatory markers between IBD and non-IBD (control) participants.
- Conditions
- Gastro-Intestinal Disorder, Crohn Disease, Ulcerative Colitis, Inflammatory Bowel Diseases
- Trial name
- NAZA (NCT06956703)
- Where
- United Kingdom
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Inflammatory Bowel Diseases, Crohn's Disease
A 5-year Longitudinal Observational Study of Patients Undergoing Therapy for Inflammatory Bowel Disease
TARGET-IBD is a 5-year, longitudinal, observational study of adult and pediatric patients (age 2 and above) being managed for Inflammatory Bowel Disease (IBD) in usual clinical practice.
- Conditions
- Inflammatory Bowel Diseases, Crohn's Disease, Ulcerative Colitis, Indeterminate Colitis
- Trial name
- TARGET-IBD (NCT03251118)
- Where
- 37 sites in United States
- Volunteers
- 15,000 people
- Sponsor
- Target PharmaSolutions, Inc.
Inflammatory Bowel Disease, Crohn's Disease
Monroe County Inflammatory Bowel Disease (IBD) Registry
This phase is to register all subjects in Monroe County, New York with Inflammatory Bowel Disease (IBD) not already included to update the database for years 1990-2003.
- Conditions
- Inflammatory Bowel Disease, Crohn's Disease, Ulcerative Colitis
- Trial name
- NCT01032525
- Volunteers
- 720 people
- Sponsor
- University of Rochester
Inflammatory Bowel Disease, Ulcerative Colitis
Safety of Anti-tumor Necrosis Factor (TNF) Monoclonal Antibodies in Inflammatory Bowel Disease
Anti-TNF (tumor necrosis factor) monoclonal antibodies have revolutionized management of Inflammatory bowel disease. Their common features include high efficacy but also immunogenicity and increased infection risk.
- Conditions
- Inflammatory Bowel Disease, Ulcerative Colitis, Crohn's Disease, Indeterminate Colitis
- Trial name
- SATIMOS (NCT02066272)
- Where
- 2 sites in Poland
- Volunteers
- 400 people
- Sponsor
- Maria Sklodowska-Curie National Research Institute of Oncology
Inflammatory Bowel Disease, Crohn Disease
High Dose Interval Vitamin D Supplementation in Patients With Inflammatory Bowel Disease Receiving Biologic Therapy
The investigators will be administering oral high dose interval vitamin D, concurrently when participants are receiving biologic therapy for their inflammatory bowel disease.
- Conditions
- Inflammatory Bowel Disease, Crohn Disease, Ulcerative Colitis, Vitamin D Deficiency
- Trial name
- NCT04331639
- Testing
- vitamin D3
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Boston Children's Hospital
Crohn Disease, Ulcerative Colitis
Resistant Starch in Pediatric Inflammatory Bowel Disease (Crohn's Disease or Ulcerative Colitis)
The purpose of the study is determine if a plant-based resistant starch that is optimized for the individual will target the underlying cause of inflammatory bowel disease and restore a "healthier" gut microbiome in pediatric…
- Conditions
- Crohn Disease, Ulcerative Colitis, Inflammatory Bowel Diseases
- Trial name
- NCT04522271
- Testing
- Resistant Starch
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Children's Hospital of Eastern Ontario
Crohns Disease, Colitis, Ulcerative
A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants
The purpose of this study is to evaluate long-term safety of subcutaneous guselkumab in pediatric participants with moderately to severely active ulcerative colitis, or moderately to severely active Crohn's disease, or juvenile…
- Conditions
- Crohns Disease, Colitis, Ulcerative, Arthritis, Psoriatic, Arthritis, Juvenile
- Trial name
- TRILOGY (NCT06663332)
- Testing
- Guselkumab
- Where
- 53 sites in United States, Argentina and 16 more
- Volunteers
- 196 people
- Sponsor
- Janssen Research & Development, LLC
Pancreatitis, Inflammatory Bowel Diseases
Thiopurine Induced Pancreatitis in IBD Patients
Azathioprine (AZA) and its metabolite 6-mercaptopurine (6-MP) were developed over 50 years ago by Gertrude Elion and George Hitchings and were initially used clinically in the management of childhood leukemia and organ…
- Trial name
- NCT02281799
- Testing
- Azathioprine
- Where
- Israel
- Sponsor
- Shaare Zedek Medical Center
Ulcerative Colitis
ADAPT Adacolumn Pediatric Trial in Ulcerative Colitis
Children aged up to 18 years with moderately active Ulcerative Colitis (PUCAI:35-64) will receive one weekly Adacolumn® apheresis treatment over 5 consecutive weeks, followed by up to 3 optional Adacolumn® apheresis treatments…
- Trial name
- NCT00781638
- Testing
- Adacolumn®
- Volunteers
- 24 people
- Sponsor
- Otsuka Frankfurt Research Institute GmbH
Ulcerative Colitis (UC)
A Multicenter, Randomized, Double-Blind, Placebo Controlled Induction Study to Evaluate the Efficacy and Safety of Risankizumab in Participants With Moderately to Severely Active Ulcerative Colitis
The objectives of Sub-Study 1 are to evaluate the efficacy, safety, and pharmacokinetics of risankizumab as induction treatment in subjects with moderately to severely active ulcerative colitis (UC), and to identify the…
- Trial name
- NCT03398148
- Testing
- risankizumab IV, risankizumab SC
- Where
- 430 sites in United States, Argentina and 42 more
- Volunteers
- 1,558 people
- Sponsor
- AbbVie
Crohn Disease, Ulcerative Colitis
Ultra-proactive Therapeutic Drug Monitoring in Inflammatory Bowel Disease
This is a comparative pragmatic trial in patients with UC and CD on maintenance treatment with IFX. All IBD patients from cohort A with maintenance IFX treatment at a referral IBD clinic are prospectively included between June…
- Trial name
- NCT04775732
- Testing
- infliximab therapeutic drug monitoring
- Where
- 2 sites in Belgium
- Volunteers
- 187 people
- Sponsor
- Imelda GI Clinical Research Center
Inflammatory Bowel Disease, Ulcerative Colitis
Efficacy of Energy Therapy in the Management of Chronic Pain Medical Condition in Children and Adolescents.
Paediatric and adolescent patients with chronic pain associated with their medical condition will be invited to participate in this study.
- Conditions
- Inflammatory Bowel Disease, Ulcerative Colitis, Crohn Disease, Chronic Pancreatitis
- Trial name
- ET&CP (NCT05394272)
- Testing
- Energy Therapy - Pranic Healing
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- King's College Hospital NHS Trust
Inflammatory Bowel Disease, Ulcerative Colitis
Web-based Monitoring in Children and Adolescents With Inflammatory Bowel Disease
The investigators hypothesize that E-health - web based monitoring of disease and treatment - in young patients with chronic inflammatory disease (IBD) can improve the disease course and quality of life.
- Conditions
- Inflammatory Bowel Disease, Ulcerative Colitis, Crohn´s Disease
- Trial name
- NCT01860651
- Testing
- Web-monitoring
- Where
- Denmark
- Volunteers
- 103 people
- Sponsor
- Hvidovre University Hospital