Clinical trials: Upper Endoscopy
Hypoxia
Comparison of Hypoxia Between HFNC and SNC in Patient Undergoing UGI Endoscopic Procedures in Deep Sedation
Hypoxia frequently occurs as a complication during upper gastrointestinal endoscopic procedures performed under deep sedation. Traditional oxygen delivery methods, such as the simple nasal cannula, are commonly used to prevent…
- Trial name
- NCT06482879
- Testing
- Oxygen delivery
- Where
- Nepal
- Volunteers
- 122 people
- Sponsor
- National Academy of Medical Sciences, Nepal
Upper GI Bleeding
Inhalation of Sevoflurane Versus Intravenous Midazolam,Ketamine,Propofol For Pediatrics Undergoing Upper GI Endoscopy
In the field of pediatric gastroenterology, upper gastrointestinal endoscopy has established itself as a diagnostic and therapeutic tool. In order to increase patient tolerance during this procedure, deep sedation is essential.
- Trial name
- NCT05474937
- Testing
- Sevoflurane Inhalation Solution, Midazolam, Ketamine and Propofol
- Where
- Egypt
- Volunteers
- 74 people
- Sponsor
- Zagazig University
Upper Gastrointestinal Bleeding
A Double Blind Study Comparing Two Doses of IV Esomeprazole After Successful Endoscopic Therapy
A bleeding peptic ulcer remains a serious medical problem with significant morbidity and mortality. Endoscopic therapy significantly reduces further bleeding, surgery, and mortality in patients with bleeding peptic ulcers and is…
- Trial name
- NCT01275937
- Testing
- Esomeprazole
- Where
- Taiwan
- Volunteers
- 65 people
- Sponsor
- Taipei Medical University
Pattern of Upper Gastrointestinal Lesions
Pattern of Upper Gastrointestinal Lesions in Upper Egypt : Clinical, Endoscopic and Pathological Evaluation
Upper Gastrointestinal (UGI) symptoms are among the commonest complaints for which patients seek medical attention, with the annual prevalence of dyspepsia approximating 25% .
- Trial name
- NCT04328324
- Testing
- Endoscopy
- Volunteers
- 100 people
- Sponsor
- Assiut University
Pain
Analgesia During Pediatric Digestive Endoscopy: a Comparison of Two Protocols for Procedural Sedation
The purpose of this study is to determine whether ketamine, midazolam, and meperidine are more effective than midazolam and meperidine alone for procedural sedation and analgesia in pediatric digestive endoscopy.
- Trial name
- NCT01168492
- Testing
- ketamine
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- Université de Montréal
Crohn Disease (CD)
Evaluation of the Efficacy of Local Budesonide Treatment in Children with Crohn's Disease Located in the Esophagus And/or Stomach And/or Duodenum
Crohn's disease (CD) is an inflammatory bowel disease characterized by chronic symptoms that include periods of exacerbation and remission.
- Trial name
- BETHESDa-CD (NCT06719622)
- Testing
- budesonide, omeprazole (proton pump inhibitor)
- Where
- 3 sites in Poland
- Volunteers
- 114 people
- Sponsor
- Medical University of Warsaw
Gastroscopy, Barrett's Esophagus
Real-life Prospective Evaluation of Computer-aided Detection (CAD) of Barrett's Neoplasia
Barrett's oesophagus is a pre-cancerous condition in which normal cells in the lining of gullet undergo cell changes and this increases the risk of developing adenocarcinoma (a type of cancer) of the gullet.
- Trial name
- MetaVision (NCT05965921)
- Where
- United Kingdom
- Volunteers
- 137 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Upper Gastrointestinal Submucosal Tumors (SMTs), Gastrointestinal Stromal Tumors (GISTs)
ESTD vs. VATS for Upper Gastrointestinal Submucosal Tumors
The purpose of this study is to determine the efficacy and safety of endoscopic submucosal tunnel dissection (ESTD) compared with video-assisted thoracoscopic surgery (VATS) in the treatment of upper gastrointestinal submucosal…
- Conditions
- Upper Gastrointestinal Submucosal Tumors (SMTs), Gastrointestinal Stromal Tumors (GISTs), Leiomyoma
- Trial name
- NCT01768104
- Testing
- ESTD, VATS
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Nanfang Hospital, Southern Medical University
C.Medical Procedure; Digestive System, Disorder of Upper Gastrointestinal Tract
Lidocaine Spray on an Endoscope to Improve Tolerance to Endoscopy
The investigators tested whether a new method which additional lidocaine spray on the tip of endoscope can increase the tolerance of examinee during endoscopy than conventional pharyngeal anesthesia alone.
- Conditions
- C.Medical Procedure; Digestive System, Disorder of Upper Gastrointestinal Tract, Tolerance
- Trial name
- NCT02307773
- Testing
- Case Group
- Where
- South Korea
- Volunteers
- 497 people
- Sponsor
- Cheju Halla General Hospital
Esophageal Varices
Wired Magnetically Assisted Capsule Endoscopy and Esophageal Varices
The goal of this clinical trial is to compare the safeness and effectiveness of traditional esophagogastroduodenoscope (EGD) and wired magnetically assisted capsule endoscopy (MACE) in the diagnosis of esophageal varices in…
- Trial name
- NCT06017102
- Testing
- wired magnetic assisted capsule endoscopy, esophagogastroduodenoscopy
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Pediatric Gastrointestinal Disorders, Chronic Abdominal Pain in Children
Role and Diagnostic Yield of Upper Endoscopy in Children With Chronic Abdominal Pain
Chronic abdominal pain is a common problem in children and may be caused by functional or organic gastrointestinal disorders. While many children have no identifiable structural disease, some may have conditions that can be…
- Conditions
- Pediatric Gastrointestinal Disorders, Chronic Abdominal Pain in Children, Upper Endoscopy
- Trial name
- UGI-CAP (NCT07372976)
- Testing
- Upper Gastrointestinal Endoscopy
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Assiut University
Foreign Body Ingestion
A Novel Strategy for Endoscopic Dual-instrument Retrieval of Upper GI Foreign Body
We describe a single-center, retrospective case series (n = 10) for the utilization of dual instruments to extract foreign body at physiological narrowing.
- Trial name
- NCT07649382
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Shanghai Zhongshan Hospital
Upper Gastrointestinal Bleeding
Trial of Hemospray Plus Epinephrine Injection Versus Endoscopic Hemoclip
The non-variceal upper gastrointestinal bleeding is defined as gastrointestinal bleeding located proximal to the angle of Treitz, whose cause is not related to esophagogastric varices or gastropathy of portal hypertension.
- Trial name
- NCT02537353
- Testing
- Metal clips, Hemospray, Endoscopy Exam
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo General Hospital
Gastric Residue, Preoperative Fasting
Preoperative Fasting Duration and Gastric Residue in Pediatric Upper Gastrointestinal Endoscopy
This retrospective observational study aims to evaluate the relationship between preoperative fasting duration and gastric residue in pediatric patients undergoing upper gastrointestinal endoscopy for gastrointestinal symptoms or…
- Conditions
- Gastric Residue, Preoperative Fasting, Upper Gastrointestinal Endoscopy
- Trial name
- NCT07614919
- Testing
- Upper Gastrointestinal Endoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Bursa Sevket Yilmaz Training and Research Hospital
Endoscopy
Is End Tidal CO2 Level Elevation During Upper Endoscopy With CO2 Gas Insufflation Physiologically Significant
During the course of an endoscopic procedure, air has historically been used to inflate the lumen to provide adequate visualization and allow for the endoscope to advance as necessary.
- Trial name
- ETCO2 (NCT04541667)
- Testing
- Air, Carbon Dioxide
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Nebraska
Dysphagia, Respiratory Complications
Trial- Dysphagia From ETT or GI Endoscopy
The purpose of this study is to conduct a randomized clinical trial to compare the incidence of dysphagia in patients receiving general anesthesia with and without an endotracheal tube for Upper gastrointestinal endoscopy.
- Trial name
- NCT02460055
- Testing
- endotracheal tube, propofol, Fentanyl
- Volunteers
- healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Hypoxemia
POM vs HFNC for Hypoxemia Prevention in Children
Upper gastrointestinal endoscopy is a commonly performed diagnostic and therapeutic procedure in children, allowing evaluation of the esophagus, stomach, and duodenum, as well as interventions such as biopsy, foreign body…
- Trial name
- NCT07234188
- Testing
- Procedural Oxygen Mask, High-Flow Nasal Cannula
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bedirhan Günel
Peptic Ulcer
Administration of High-Dose Intravenous Proton Pump Inhibitor for Upper Gastrointestinal Bleeding Prior to Endoscopy
To evaluate if intravenous PPI infusion, when administered prior to endoscopy, hastens resolution of bleeding stigmata and thereby facilitates endoscopic examinations and reduces the need for endoscopic treatment.
- Trial name
- NCT00164866
- Testing
- Omeprazole
- Where
- China
- Volunteers
- 638 people
- Sponsor
- Chinese University of Hong Kong
Pediatric, Gastroscopy
Effect of Esketamine on 95% Induction Dose of Remimazolam
As an invasive operation, gastroscopy will cause children's nervousness, anxiety and uncooperative behavior, and even lead to the risk of bleeding and perforation, which will also affect the accuracy of the examination…
- Conditions
- Pediatric, Gastroscopy, ED95, Sedation
- Trial name
- EEIDR (NCT06303037)
- Testing
- Remimazolam besylate and low-dose Esketamine, Remimazolam besylate and Medium dose Esketamine
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Gastro Esophageal Reflux, Gastric Ulcer
Comparison Between Two Types of Sedation for Elective Upper Endoscopy Procedures
Sedation is defined as the act of administrating a sedative drug to produce a state of calm or sleep. Sedation is commonly given to a patient in hospital settings to provide a tolerable and pleasant experience by relieving…
- Conditions
- Gastro Esophageal Reflux, Gastric Ulcer, Sedation Complication
- Trial name
- NCT04410211
- Testing
- Sevoflurane, Midazolam injection
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Malaya