Clinical trials: Upper Extremity
Unilateral Cerebral Palsy
Wereables for Upper Limb Functionality in Hemiparesis
The project is configured as a national interventional study that aims to determine the effectiveness of an intervention strategy using wearable technology, tailored to improve function (WeFun-wearable), on the spontaneous use of…
- Trial name
- WeFun (NCT06872736)
- Testing
- WeFun-wearable activated, WeFun-wearable desactivated
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidade da Coruña
Excessive Daytime Sleepiness, Cataplexy
Once-Nightly Sodium Oxybate for Treatment of Excessive Daytime Sleepiness and Cataplexy in Narcolepsy
The purpose of this study is to determine whether once-nightly FT218 is safe and effective for the treatment of excessive daytime sleepiness and cataplexy in subjects with narcolepsy.
- Conditions
- Excessive Daytime Sleepiness, Cataplexy, Narcolepsy
- Trial name
- NCT02720744
- Testing
- FT218
- Where
- 57 sites in United States, Australia and 4 more
- Volunteers
- 212 people
- Sponsor
- Avadel
Plaque Psoriasis
A Study of Apremilast in Pediatric Participants in Children With Mild to Moderate Plaque Psoriasis
The primary objective of this post-marketing study is to assess the safety and tolerability of apremilast in pediatric participants (ages 6 through 17 years) with mild to moderate plaque psoriasis.
- Trial name
- NCT06088199
- Testing
- Apremilast
- Where
- 30 sites in United States
- Volunteers
- 51 people
- Sponsor
- Amgen
Injury of Other Nerves at Wrist and Hand Level of Unspecified Arm, Initial Encounter
Conversion of Seddon III Nerve Injury to Seddon I/II Nerve Injury
This study will evaluate the safety and efficacy of PEG 3350 for use in nerve repair.
- Trial name
- NCT03236064
- Testing
- Polyethylene Glycols
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- WellSpan Health
Duchenne Muscular Dystrophy (DMD)
Study of Eteplirsen in DMD Patients
The main objective of this study is to provide evidence of efficacy of eteplirsen (AVI-4658) in Duchenne muscular dystrophy (DMD) patients that are amenable to skipping exon 51.
- Trial name
- PROMOVI (NCT02255552)
- Testing
- eteplirsen
- Where
- 37 sites in United States
- Volunteers
- 109 people
- Sponsor
- Sarepta Therapeutics, Inc.
Gastrointestinal Function, Mental Well-being
The Effects of Early Postoperative Heat Application and Abdominal Massage on Gastrointestinal Function
This randomised controlled trial was designed to determine the effect of early-stage heat application and abdominal massage on patients' gastrointestinal function and mental well-being following hip fracture surgery.
- Trial name
- NCT07208955
- Testing
- heat application, abdominal massage, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Cukurova University
B Cell Lymphoma, Acute Lymphoblastic Leukemia
Anti-CD22 Chimeric Antigen Receptor (CAR)-Modified T Cell Therapy for Relapsed Refractory B-cell Malignancies
This is a single-center, open-label, single-arm study to evaluate the safety and efficacy of anti-CD22 CAR-T cells in patients with relapsed or refractory B-cell Malignancies.
- Trial name
- NCT04007978
- Testing
- Third generation CAR-T cells
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Acute Pyelonephritis, Complicated Urinary Tract Infection
A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Meropenem-Vaborbactam in Children With Complicated Urinary Tract Infection, Including Acute Pyelonephritis
The primary objective of the study is to assess the safety and tolerability of meropenem-vaborbactam administered by intravenous (IV) infusion in children 3 months and above to less than 12 years with complicated urinary tract…
- Trial name
- NCT06672978
- Testing
- Meropenem-Vaborbactam, Antibiotics
- Where
- 26 sites in United States, Bulgaria and 4 more
- Volunteers
- 66 people
- Sponsor
- Rempex (a wholly owned subsidiary of Melinta Therapeutics, LLC)
Hemiplegic Cerebral Palsy
Electromyography Biofeedback Training Versus Mirror Therapy on Muscle Activity, Range of Motion and Function of Upper Limb in Children With Hemiplegia
One of the main motor control issues in hemiplegic CP is spasticity, which affects the flexor muscles of the upper limb. This spasticity causes the limb to adopt a flexed posture, limiting the range of motion and contributing to…
- Trial name
- NCT07818616
- Testing
- Neurotrac Simplex electromyography biofeedback device, Mirror, a designed physical therapy program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Parkinson Disease
Predicting Motor Learning of an Upper Limb Task Based on Behavioral and Disease-specific Characteristics in Patients With Parkinson's Disease
Manual dexterity deficits and loss of motor automaticity are commonly seen in patients with Parkinson's disease (PD). Amongst these problems, using a touchscreen is becoming increasingly burdensome.
- Trial name
- NCT06738290
- Testing
- Targeted home-based touchscreen training
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- KU Leuven
Fractures, Bone, Upper Extremity Injury
Ultrasonography in Fracture Management
The bone fracture is usually diagnosed using an X-ray examination (the method of choice). However, in the case of the youngest patients (children and adolescents), it carries a potential risk of X-ray radiation exposure.
- Conditions
- Fractures, Bone, Upper Extremity Injury, Healing Fracture of Bone, Vascularization
- Trial name
- UFrac (NCT04501510)
- Testing
- Ultrasonographic examination validation and testing
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- University of Warmia and Mazury
Lymphoma
Study Evaluating the Efficacy and Safety With CAR-T for Recurrent or Refractory Diffuse Large B Cell Lymphoma
This single-arm, multicenter Phase 2 study will treat the patients who have Recurrent or refractory diffuse large B cell lymphoma with an infusion of the patient's own T cells that have been genetically modified to express a…
- Trial name
- EECBL (NCT02728882)
- Testing
- CD19-targeted CAR-T cells
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Sinobioway Cell Therapy Co., Ltd.
Immune Thrombocytopenia, Treatment
Avatrombopag in the Treatment of Pediatric Immune Thrombocytopenia
To evaluate the safety and efficacy of avatrombopag in the treatment of pediatric primary immune thrombocytopenia in patients who have been treated with eltrombopag before and switched to avatrobopag because of poor efficacy…
- Trial name
- NCT06281327
- Testing
- Avatrombopag
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Institute of Hematology & Blood Diseases Hospital, China
Hemiplegia
Effect of Biofeedback and Functional Electrical Stimulation in Children
40 children with hemiplegia cerebral palsy from both sex will be recruited from outpatient clinic of abo resh hospital ,their age ranged from 5-10 years
- Trial name
- NCT06729190
- Testing
- biofeedback, Physical therapy program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Ulcerative Colitis
A Study Evaluating the Effects of Filgotinib in Children and Teenagers With Ulcerative Colitis
The aim of this study is to evaluate the efficacy, safety, tolerability, and pharmacokinetics (PK) of filgotinib as a treatment for UC in children and adolescents aged from 8 to less than 18 years.
- Trial name
- Galapeduca (NCT06865417)
- Testing
- Filgotinib
- Where
- 46 sites in Belgium, Croatia and 11 more
- Volunteers
- 80 people
- Sponsor
- Alfasigma S.p.A.
Mild Cognitive Impairment (MCI), Moderate Cognitive Impairment
Comparative Effects of Integrated Versus Sequential Approaches to Dual-Task Training in Elderly With Mild to Moderate Cognitive Impairment
Mild and Moderate cognitive impairment is a condition characterized by a noticeable decline in cognitive abilities, including memory and thinking skills, which is greater than expected for an individual's age but does not…
- Trial name
- nill (NCT07775079)
- Testing
- Integrated Dual-Task Training, Sequential Dual-Task Training
- Where
- Pakistan
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Shifa Tameer-e-Millat University
Blood Vessel Prosthesis
Reverse-Loop Upper Arm Arteriovenous Graft
Background: A conventional configured prosthetic arteriovenous graft (AVG) usually wastes most upper arm vessels that a reverse-loop design may conserve.
- Trial name
- NCT00708825
- Where
- Taiwan
- Volunteers
- 7 people
- Sponsor
- Far Eastern Memorial Hospital
Erbs Palsy
Effects of Scapular Mobilization on Upper Limb Function
Erb's Palsy is a physical impairment resulting from an injury to the upper trunk of the brachial plexus and is associated with paralysis of the upper limb.
- Trial name
- NCT06198218
- Testing
- Scapular mobilization, Conventional physical therapy program
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Anxiety Generalized
Web-based Single-session Growth Mindset Intervention for Adolescent Anxiety
Anxiety disorders are the most common mental disorders worldwide. In Hong Kong, 7% of adolescents are diagnosed with anxiety disorders, and one in every four secondary school students reports clinical-level anxiety symptoms.
- Trial name
- NCT05027880
- Testing
- Web-based single-session growth mindset intervention for adolescent anxiety
- Where
- Hong Kong
- Volunteers
- 731 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Surgical Site Infections, Hypothermia
Feedback on Perioperative Temperature Management and Patient Outcomes: Three-arm Trial to Compare Feedback
The investigators aim to assess the impact of benchmarked and ranked feedback on anesthesiologists' perioperative temperature management and subsequent patient outcomes.
- Trial name
- NCT02414191
- Testing
- Benchmarked Feedback, Ranked Feedback
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
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