Clinical trials: Upper Extremity Deformities, Congenital
Rett Syndrome
Measuring Impact of Computer Gaming on Arm Use in Rett Syndrome
Using a tele-research approach, we will recruit, enroll, guide and support carers and participants to engage in computer based activities (modified virtual reality) with the primary outcome of reducing stereotypies and increasing…
- Trial name
- NCT05012475
- Testing
- Modified Virtual Reality Gaming
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Georgetown University
Upper Limb Deformities, Congenital
Customized Self-Controlled Power-Driven or Mechanical Orthoses for the Upper Limb - A Pilot Study
Patients with congenital or acquired upper limb structural abnormalities and peripheral nerve or brachial plexus palsies have significant loss of function.
- Trial name
- NCT04199975
- Testing
- Orthoses
- Where
- Hong Kong
- Volunteers
- 10 people
- Sponsor
- Chinese University of Hong Kong
Cerebral Palsy, Stroke
Feasibility of the Portable YouGrabber System
The aim of the study is to determine the feasibility of the portable version of the YouGrabber® system in children with central motor disorders.
- Conditions
- Cerebral Palsy, Stroke, Traumatic Brain Injury, Meningomyelocele
- Trial name
- YouGrabber (NCT02368223)
- Testing
- YouGrabber
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- University Children's Hospital, Zurich
Cerebral Palsy, Stroke
Reliability of the Melbourne Assessment
The aim of the study is to investigate the reliability of the Melbourne Assessment.
- Conditions
- Cerebral Palsy, Stroke, Traumatic Brain Injury, Meningomyelocele
- Trial name
- NCT02595411
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University Children's Hospital, Zurich
Primary Ciliary Dyskinesia
Upper Extremity Exercise Capacity, Muscle Oxygenation, Balance in Patients With Primary Ciliary Dyskinesia
The main aim of the study is to evaluate upper extremity exercise capacity and muscle oxygenation in patients with primary ciliary dyskinesia.
- Trial name
- NCT04895150
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Gazi University
Muscular Dystrophies, Muscular Dystrophy, Duchenne
A Study of Deramiocel (CAP-1002) in Ambulatory and Non-Ambulatory Patients With Duchenne Muscular Dystrophy
HOPE-3 is a two cohort, Phase 3, multi-center, randomized, double-blind, placebo-controlled clinical trial evaluating the efficacy and safety of a cell therapy called deramiocel (CAP-1002) in study participants with Duchenne…
- Conditions
- Muscular Dystrophies, Muscular Dystrophy, Duchenne, Muscular Disorders, Atrophic, Muscular Diseases
- Trial name
- HOPE-3 (NCT05126758)
- Testing
- Deramiocel (CAP-1002)
- Where
- 20 sites in United States
- Volunteers
- 106 people
- Sponsor
- Capricor Inc.
Congenital Hand Deformities
Syndactyly Repair: Comparison of Skin Graft and No Skin Graft Techniques
Syndactyly is a relatively common congenital abnormality of the hand occurring approximately 1 out of 2500 live births (1). It can be simple, meaning only skin and soft tissues are shared, or complex, meaning the bone or nail…
- Trial name
- NCT01416090
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Utah
Muscular Dystrophies, Muscular Dystrophy, Duchenne
A Study of CAP-1002 in Ambulatory and Non-Ambulatory Patients With Duchenne Muscular Dystrophy
HOPE-2 is a double-blind clinical trial evaluating the safety and efficacy of a cell therapy called CAP-1002 in study participants with Duchenne Muscular Dystrophy (DMD).
- Conditions
- Muscular Dystrophies, Muscular Dystrophy, Duchenne, Muscular Disorders, Atrophic, Muscular Diseases
- Trial name
- HOPE-2 (NCT03406780)
- Testing
- CAP-1002
- Where
- 9 sites in United States
- Volunteers
- 20 people
- Sponsor
- Capricor Inc.
Down Syndrome
Effects of Task-oriented Training on Visual-motor Integration and Upper Limb Function in Children With Down Syndrome
The condition known as Down Syndrome (DS) is caused by trisomy 21, or the presence of an extra copy of chromosome 21. DS is the most common survivable autosomal aneuploidy and one of the genetically complicated problem compatible…
- Trial name
- NCT06943261
- Testing
- task oriented training, conventional therapy
- Volunteers
- 28 people
- Sponsor
- Riphah International University
Limb Girdle Muscular Dystrophy
A Gene Transfer Single Dose Study to Evaluate the Safety, Tolerability and Efficacy of SRP-9003 in Non-Ambulatory and Ambulatory Participants With Limb Girdle Muscular Dystrophy, Type 2E/R4 (Beta-Sarcoglycan [β-SG] Deficiency)
The primary purpose of this study is to evaluate the safety of SRP-9003 and to quantify expression of β-SG in the skeletal muscle of participants with limb-girdle muscular dystrophy, type 2E/R4 (LGMD2E/R4).
- Trial name
- NCT05876780
- Testing
- SRP-9003
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Sarepta Therapeutics, Inc.
Limb Deformities, Congenital, Upper Extremity Deformities, Congenital
Evaluation of 3D Printed Myoelectric Prosthetic Devices in Children With Upper Congenital Limb Deficiency
This will be a prospective study over a 14-month duration with clinical evaluations throughout. Limitless Solutions will provide prosthetics and training system for study subjects that qualify for enrollment.
- Conditions
- Limb Deformities, Congenital, Upper Extremity Deformities, Congenital, Congenital Abnormalities
- Trial name
- NCT05547308
- Testing
- 3D myoelectric prosthetic device
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Orlando Health, Inc.
Cystic Fibrosis
Upper Extremity Exercise Capacity, Muscle Oxygenation, Balance in Patients With Cystic Fibrosis
The primary aim of the study is to evaluate upper extremity exercise capacity, muscle oxygenation, balance and physical activity level in patients with cystic fibrosis..
- Trial name
- NCT04803643
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gazi University
Camptodactyly
Treatment of Camptodactyly With Radial Longitudinal Flap Versus Full-Thickness Skin Graft
The goal of this randomized clinical trial is to compare two surgical techniques used for skin coverage after surgical correction of camptodactyly, a condition in which one or more fingers remain bent and cannot be fully…
- Trial name
- NCT07786701
- Testing
- Radial Longitudinal Flap, Full-Thickness Skin Graft
- Where
- Brazil
- Volunteers
- 42 people
- Sponsor
- Associação de Assistência a Criança Deficiente
Duchenne Muscular Dystrophy (DMD)
Digital Monitoring of Upper Limb Function in Non-Ambulant DMD
Duchenne Muscular Dystrophy (DMD) is a rare genetic disorder caused by the absence of dystrophin, leading to progressive muscle degeneration.
- Trial name
- Acti-nRoll (NCT07664124)
- Testing
- Performance of the Upper Limb (PUL) Test, Brook test, Dynamometric measurements of muscle strength
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Liege
Obstetric Brachial Plexus Injury, Birth Related Brachial Plexus Injury
Investigating the Effectiveness of Graded Motor Imagery Training in Children With Obstetric Brachial Plexus Injury
The aim of this study is to investigate the effect of graded motor imagery training on upper extremity motor function, proprioception, functional mobility, balance and quality of life in patients with obstetric brachial plexus…
- Conditions
- Obstetric Brachial Plexus Injury, Birth Related Brachial Plexus Injury, Neonatal Brachial Plexus Palsy
- Trial name
- NCT06966544
- Testing
- Conventional Physiotherapy, Graded Motor Imagery
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Izmir Bakircay University
Muscular Dystrophies
Wearability, Saefty and Usability Assessment for the Upper Limb Exoskeleton BRIDGE/EMPATIA
The study is a feasibility study or pilot study, that is a clinical investigation to acquire the preliminary information on a motorized exoskeleton (BRIDGE / EMPATIA exoskeleton) for the movement of the upper limb in order to…
- Trial name
- NCT03951844
- Testing
- BRIDGE/EMPATIA exoskeleton
- Where
- 2 sites in Italy
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Alessandra Pedrocchi
Duchenne Muscular Dystrophy
Validity and Reliability of the 6 Minute Pegboard Ring Test
This study aimed to investigate the validity and reliability of 6PBRT in individuals with DMD and its applicability on these patients.
- Trial name
- NCT06174025
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Çağtay Maden
Neurologic Diseases, Hemiparesis
NuroSleeve Powered Brace & Stimulation System to Restore Arm Function
The purpose of this study is to investigate if a person with weakness or paralysis in one or both arms, can use the NuroSleeve combined powered arm brace (orthosis) and muscle stimulation system to help restore movement in one…
- Conditions
- Neurologic Diseases, Hemiparesis, Quadriplegia, Muscular Dystrophies
- Trial name
- NCT04798378
- Testing
- Neurosleeve
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Duchenne Muscular Dystrophy
Upper Extremity Muscle Strength, Balance and Functional Skills in DMD
This study aims to examine the relationship between upper extremity muscle strength, balance and functional skills of children with DMD.
- Trial name
- NCT06379906
- Testing
- Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Halic University
Pediatric Patients, Orthopedic Surgery
Nociception Level Index as a Verbal Tool of Pain in Children
60 children under 6 years old, scheduled for orthopedic surgery for limb fracture or neuromuscular and bone deformities will be randomized by closed envelope method into two groups (n=30) either receiving standard pain management…
- Conditions
- Pediatric Patients, Orthopedic Surgery, Extremity Fractures Lower, Extremity Fractures Upper
- Trial name
- NCT05716243
- Testing
- The nociception level index monitorization, The nociception level index measurement;postoperative
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Haseki Training and Research Hospital