Clinical trials: Upper Extremity Motor Function
Hemiplegia, Cerebral Palsy
Bimanual Training in Children With Hemiplegia
A randomized control trial of bimanual training in children with hemiplegia. The protocols have been developed at Columbia University to be child friendly and draws upon our experience since 1997 with constraint-induced movement…
- Conditions
- Hemiplegia, Cerebral Palsy, Children
- Trial name
- HABIT (NCT01413594)
- Testing
- HABIT
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Teachers College, Columbia University
COPD
Prospective Study Comparing Different Modalities of Oxygen Delivery During Assessment of Functional Exercise Capacity
Objectives: The objective of this study is to determine if any differences exist between the varying modes of portable oxygen delivery systems including liquid oxygen, a portable concentrator, portable devices filled at home from…
- Trial name
- NCT00484562
- Testing
- Standard oxygen delivery system, Homefill oxygen delivery system, Helios oxygen delivery system
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Missouri-Columbia
Hemiparesis, Unilateral Cerebral Palsy
Effects and Mechanisms of Sensory Afferent Electrostimulation on Upper Limb Function in Patients With Hemiparesis
The goal for this project is to investigate the effects of a 5-week SAES therapy in addition to conventional therapy on both behavioural (sensory and motor) and neurological measures and the underlying mechanisms of treatment…
- Trial name
- SAES (NCT06536634)
- Testing
- SAES, TAU
- Where
- Switzerland
- Volunteers
- 34 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Cerebral Palsy
Effects of Forms of Modified CIT on Upper Extremity Performance in Cerebral Palsy
The purpose of this study will employ clinical assessment tools to examine the effects of modified constraint-induced therapy (mCIT) on the more affected upper extremity of children with cerebral palsy.
- Trial name
- NCT01643239
- Testing
- Hospital-based mCIT restraint of the unaffected arm and practice of the affected arm, Hospital-based mCIT, Hospital-based TR
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Cerebral Palsy
Intensive Bimanual Intervention in Cerebral Palsy Children
Motor disorders related to cerebral palsy are often accompanied by sensory, cognitive, perceptive, communication and behavioural impairments.
- Trial name
- NCT05423171
- Testing
- Intensive bimanual therapy
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Laval University
Cerebrovascular Accident
Effects of Perfetti's Method on Cognition, Dexterity and Sensory Motor Function of the Upper Extremity in Stroke Patients
Null Hypothesis (HO) There is no difference between the effects of Perfetti's Method versus routine physical therapy on cognition, dexterity, and sensory motor function of the upper extremity in stroke patients.
- Trial name
- NCT05167006
- Testing
- routine physical therapy, Perfetti's method
- Where
- Pakistan
- Volunteers
- 88 people
- Sponsor
- University of Lahore
Cerebral Palsy, Spastic
The Effect of Task-oriented EMG-triggered ES on Upper Limb Motor Function in Hemiplegic Cerebral Palsy
The purpose of our study; to investigate the effects of EMG-induced ES treatment on hand functions, muscle strength, and quality of life in patients with hemiplegic CP.
- Trial name
- NCT04394819
- Testing
- electromyography-triggered electrical stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- nihal tezel
Cerebral Palsy (CP), Diplegic Cerebral Palsy
Effect of Intensive Segmental Trunk Training on Upper Extremity Function and Seated Postural Stability in Children With Spastic Diplegic Cerebral Palsy
The goal of this randomized controlled trial is to evaluate whether intensive segmental trunk training (ISTT) can improve upper extremity function and seated postural stability in children aged 4-12 years with spastic diplegic…
- Conditions
- Cerebral Palsy (CP), Diplegic Cerebral Palsy, Trunk Mobility, Upper Extremity Function
- Trial name
- NCT07692087
- Testing
- Intensive Segmental Trunk Training, Standard Physical Therapy
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- University of Lahore
Cerebrovascular Accident
Ischemic Nerve Block to Improve Hand Function in Stroke Patients
This study will determine whether impaired hand function due to stroke can be improved by blocking nerve impulses to the unaffected arm.
- Trial name
- NCT00056706
- Testing
- Transient deafferentation
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Cerebral Palsy (CP)
Intensive Rehabilitation Program for Upper Limb in Children and Adolescents With Cerebral Palsy
Cerebral palsy is the most common motor disability in children. Individuals with CP often experience significant difficulties in the use of their upper limbs, which affects their autonomy and quality of life.
- Trial name
- NCT07285837
- Testing
- Intensive Rehabilitation
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Fondation Ellen Poidatz
Spinal Muscular Atrophy
Safety and Efficacy of Intravenous OAV101 (AVXS-101) in Pediatric Patients With Spinal Muscular Atrophy (SMA)
To evaluate the safety, tolerability and efficacy of intravenous administration of OAV101 (AVXS-101) in patients with spinal muscular atrophy (SMA) with bi-allelic mutations in the survival motor neuron 1 (SMN1) gene weighing ≥…
- Trial name
- SMART (NCT04851873)
- Testing
- OAV101
- Where
- 13 sites in United States, Australia and 7 more
- Volunteers
- 24 people
- Sponsor
- Novartis Pharmaceuticals
Cerebral Palsy
Changes Induced by Early HABIT-ILE in Pre-school Children With Uni- and Bilateral Cerebral Palsy
Studying in two randomized controlled trials (RCT) the changes induced by early HABIT-ILE in functional, neuroplastic and biomechanical assessment in children with unilateral and bilateral CP.
- Trial name
- EarlyHABIT-ILE (NCT04020354)
- Testing
- HABIT-ILE, Usual Care
- Where
- 3 sites in Belgium, France and 1 more
- Volunteers
- 100 people
- Sponsor
- Université Catholique de Louvain
Cerebral Palsy
Effect of HABIT-ILE on the Body Function and Structures of Children With Cerebral Palsy
There is strong evidence that recent intensive interventions based on motor skill learning principles are efficient on functional and neuroplastic changes of children with cerebral palsy (CP).
- Trial name
- NCT04403490
- Testing
- HABIT-ILE, Conventional intervention
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Université Catholique de Louvain
Neurologic Diseases, Hemiparesis
NuroSleeve Powered Brace & Stimulation System to Restore Arm Function
The purpose of this study is to investigate if a person with weakness or paralysis in one or both arms, can use the NuroSleeve combined powered arm brace (orthosis) and muscle stimulation system to help restore movement in one…
- Conditions
- Neurologic Diseases, Hemiparesis, Quadriplegia, Muscular Dystrophies
- Trial name
- NCT04798378
- Testing
- Neurosleeve
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Athlete Assessment, Archery
Validity and Test-Retest Reliability of Reactive Neurocognitive Upper Extremity Tests in Archers
In archery, the evaluation of reaction time and neurocognitive functions plays a critical role in the management of upper extremity (UE) injuries and return-to-play (RTP) processes.
- Conditions
- Athlete Assessment, Archery, Neurocognitive Functional Performance Tests
- Trial name
- NCT07103824
- Testing
- Upper Extremity Neurocognitive Tests
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Balikesir University
Alzheimer's Disease
Effects of Group Music Therapy Interventions on Alzheimer's Disease Patients: a Three-arm Randomized Controlled Blind Study.
The purpose of this study is to determine what type of music therapy (active versus passive) approach has higher effects on clinical symptoms in advanced Alzheimer's disease patients
- Trial name
- NCT04761497
- Testing
- Actice music therapy, Watching nature videos, Passive music therapy
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Universidad Católica San Antonio de Murcia
Cerebral Palsy (CP)
Effects of Barefoot vs. Shod Whole Body Vibration Training in Children With Cerebral Palsy
Cerebral palsy (CP) refers to a group of lifelong conditions that affect the development of movement and coordination that lead to activity limitations due to damage to the developing fetal or neonatal brain tissue.
- Trial name
- NCT06596525
- Testing
- Conventional physical therapy, Barefoot Whole Body Vibration Training (WBVTb), Shod Whole Body Vibration Training (WBVTs)
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Trakya University
Cerebral Palsy, Developmental Coordination Disorder
Bootle Blast: Understanding the Family Experience
One in 60 children have a physical disability that can impact activities and participation. Occupational and physical therapies can be of great benefit, but are costly and difficult to access.
- Conditions
- Cerebral Palsy, Developmental Coordination Disorder, Developmental Disability, Autism Spectrum Disorder
- Trial name
- NCT06161168
- Testing
- Bootle Blast Play Phase (B)
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Cerebral Palsy (CP)
Effects of Motor Imagery and Action Observation on Motor Function in Unilateral Cerebral Palsy
The aim of this study is to evaluate the effects of action observation therapy and motor imagery methods, provided in addition to a conventional physiotherapy and rehabilitation program, on gross motor function, upper and lower…
- Trial name
- NCT07612371
- Testing
- motor imagery, Action observation therapy, Conventional physiotherapy group
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Bahçeşehir University
Cerebral Palsy (CP), Spastic Cerebral Palsy
Effect of Task Specific Electrical Stimulation on Upper Limb Gross Motor Skills in Children With Spastic Quadriplegia
Cerebral palsy is a non-progressive lesion of the brain occurring before 2 years of age resulting in disorders of posture and movement.( Ostensjo S, 2004)( Keles MN, 2018).
- Conditions
- Cerebral Palsy (CP), Spastic Cerebral Palsy, Quadriplegic Cerebral Palsy, Upper Limb Function
- Trial name
- NCT06925425
- Testing
- Task specific electrical stimulation ( TASES ), Designed Physical therapy program
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Kafrelsheikh University