Clinical trials: Upper Gastrointestinal Disorder
Duodenal Ulcer Bleeding
Prophylactic Injection Therapy Reduces Recurrent Bleeding In Forrest Type IIb Duodenal Ulcers
The purpose of this study is to determine whether prophylactic injection therapy reduces recurrent bleeding rate for duodenal ulcers which has the endoscopic stigmata of recent bleeding.
- Trial name
- NCT01471496
- Testing
- prophylactic injection therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Alopecia Areata, Depressive Episode
The Epidemiology, Management, and the Associated Burden of Related Conditions in Alopecia Areata
This study series consists of four related studies and aims to explore and describe many important elements of alopecia areata over three key areas: (1) the current epidemiology of alopecia areata, (2) the prevalence and…
- Conditions
- Alopecia Areata, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorders
- Trial name
- NCT04239521
- Testing
- Exposure of interest (studies 2 & 3).
- Where
- United Kingdom
- Volunteers
- 51,955 people
- Sponsor
- Momentum Data
Upper Respiratory Tract Infections, Gastrointestinal Infection
Preventive Effect of Cow's Milk Fermented With Lactobacillus Paracasei CBA L74 on Common Infectious Diseases in Children
this is a double-blind randomized placebo controlled clinical trial. 200 healthy children aged 12-48 months, attending day care or preschool for at least 5 days a week, regularly checked by the family pediatrician (FP) involved…
- Conditions
- Upper Respiratory Tract Infections, Gastrointestinal Infection, Children, Only
- Trial name
- FERCT19 (NCT05484102)
- Testing
- milk fermented with lactobacillus paracasei CBA L74
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Bari
Esophageal Varices in Cirrhosis of the Liver, Upper Gastrointestinal Bleeding
Endoscopic Variceal Ligation in Children
This is an ambispective single-center cohort study of pediatric patients with portal hypertension and esophageal varices. The study was designed to evaluate the efficacy and safety of primary prophylaxis with endoscopic variceal…
- Conditions
- Esophageal Varices in Cirrhosis of the Liver, Upper Gastrointestinal Bleeding, Endoscopy, Child
- Trial name
- NCT03943784
- Testing
- Endoscopic Variceal Ligation, Non-Selective Beta-Blocking Agent
- Volunteers
- 60 people
- Sponsor
- Hospital Vall d'Hebron
Hepatitis A Vaccine
To Evaluate the Immunogenicity and Safety of Inactivated Hepatitis A Vaccine (VITHA-A)
The objective of this study is to evaluate the safety and immunogenicity after one primary dose and one additional dose (administered twice at an interval of 6 months) of inactivated hepatitis A vaccine are administered in…
- Trial name
- NCT03654677
- Testing
- inactivated hepatitis A vaccine, Havrix Inj
- Where
- 12 sites in South Korea
- Volunteers
- 253 people, healthy volunteers welcome
- Sponsor
- Boryung Pharmaceutical Co., Ltd
UGI Bleed
Comparison of Risk Scores in Upper Gastrointestinal Bleeding
The goal of this prospective observational study is to compare the Glasgow-Blatchford Score (GBS), AIMS65, and pre-endoscopic Rockall Score in predicting outcomes among patients with upper gastrointestinal bleeding (UGIB).
- Trial name
- NCT07819942
- Where
- Nepal
- Volunteers
- 100 people
- Sponsor
- Kathmandu Medical College and Teaching Hospital
Necrotizing Enterocolitis
SMA Flow Patterns in Neonatal Transfusion
This study aims to measure the changes induced by packed red blood cell (PRBC) transfusion in the superior mesenteric artery (SMA) flow velocity and intestinal oxygenation indices in premature neonates.
- Trial name
- SPARTAN (NCT02347475)
- Testing
- Observational Study
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- University of Calgary
Wasting, Undernutrition
Improvement of Nutrition Status, Digestive Conditions, and Upper Respiratory Infections by Using Oral Nutritional Supplementation on Children in Vietnam
Evaluating the efficiency of using the nutrient production toward nutrition status (anthropometric index, the prevalence of wasting), digestive disorders, anorexia, and upper respiratory infections in children aged 24 - 71 months.
- Conditions
- Wasting, Undernutrition, Malnourished, Malnutrition
- Trial name
- NCT05570045
- Testing
- Colos Gain
- Where
- Vietnam
- Volunteers
- 600 people
- Sponsor
- Tu Nguyen Song
Upper Gastrointestinal Motility Disorders
Use of an Ambulatory Capsule to Characterize Gastrointestinal Pressure Patterns in Children
This study will test a new medical device called the SmartPill GI Monitoring System, which is now used to diagnose gastric motility disorders in adults, in children.
- Trial name
- NCT01026922
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Nationwide Children's Hospital
Gastroesophageal Reflux
Is Laparoscopic Fundoplication Better Than Open Fundoplication in Children ?
The aim of the study was to compare short- and longterm outcomes after laparoscopic and open Nissen fundoplication in children.
- Trial name
- NCT01551134
- Testing
- Fundoplication
- Where
- Norway
- Volunteers
- 88 people
- Sponsor
- Oslo University Hospital
Transfer Dysphagia, Oropharyngeal Dysphagia
Onabotulinum Toxin A (Botox) in the Treatment of Pharyngo-esophageal Dysphagia
Dysphagia in patients with stroke, multiple sclerosis, parkinsonism or dystonia can occur due to relative hypertonia of the cricopharyngeus muscle. In the resting state, muscle is contracted and relaxes only during deglutition.
- Conditions
- Transfer Dysphagia, Oropharyngeal Dysphagia, Cricopharyngeus Muscle Dysfunction
- Trial name
- NCT04695600
- Testing
- Botulinum Toxin Type A Injection [Botox]
- Where
- India
- Volunteers
- 100 people
- Sponsor
- All India Institute of Medical Sciences
Gastric Cancer, Esophagus Cancer
Exosome-based Liquid Biopsies for Upper Gastrointestinal Cancers Diagnosis
This study constitutes a case-control investigation employing a retrospective approach. Plasma samples from individuals with esophageal cancer, benign esophageal diseases, gastric cancer, benign gastric diseases, and a healthy…
- Trial name
- NCT06278064
- Testing
- Gastric Cancer, Esophagus Cancer
- Where
- 3 sites in China
- Volunteers
- 562 people, healthy volunteers welcome
- Sponsor
- Beijing Friendship Hospital
Superior Mesenteric Artery Syndrome, Somatic Symptom Disorder (DSM-5)
Fluoxetine in Refractory Superior Mesenteric Artery Syndrome by Targeting Comorbid Somatic Symptom Disorder
The goal of this interventional study is to evaluate whether fluoxetine, a selective serotonin reuptake inhibitor (SSRI), can alleviate core symptoms and reduce the need for surgical intervention in patients with refractory…
- Trial name
- NCT07115472
- Testing
- Fluoxetine
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Drainage, Laparoscopic Cholecystectomy
The Efficacy and Safety of Using Prophylactic Abdominal Drainage After Cholecystectomy
Investigators want to assess the safety and efficacy of using abdominal drainage with not using any drainage, by estimating different outcomes after laparoscopic cholecystectomy for different reasons.
- Conditions
- Drainage, Laparoscopic Cholecystectomy, Acute Cholecystitis
- Trial name
- NCT05267860
- Testing
- Prophylactic Drain
- Where
- Syria
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- University of Aleppo
Biliary Atresia
Outcome of Kasai Portoenterostomy in Biliary Atresia in Upper Egypt
Kasai portoenterostomy is the key standard operation for biliary atresia. The aim of the study is to evaluate the short-term outcome of Kasai portoenterostomy for biliary atresia infants in Upper Egypt.
- Trial name
- NCT05925543
- Testing
- Kasai portoenterostomy operation.
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Aswan University Hospital
Superior Mesenteric Artery Syndrome
Ultrasound Evaluation of Superior Mesenteric Artery Measurements in a Healthy Pediatric Population
Multicenter, prospective, observational research project on children aged from 10 to 15 years old undergoing abdominal ultrasound examinations during routine clinical practice.
- Trial name
- NCT04515251
- Testing
- Ultrasound measurements
- Where
- 2 sites in Switzerland
- Volunteers
- 289 people
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Cystic Fibrosis, Pseudomonas Aeruginosa
Sino-nasal Inhalation of Colistin in Patients With Cystic Fibrosis and Pseudomonas Aeruginosa Colonization
The purpose of this study is to determine whether the nasal inhalation of Colistin is effective to decrease the Pseudomonas aeruginosa bacterial count in the nasal lavage fluid.
- Trial name
- NCT01035853
- Testing
- Colistin
- Where
- 3 sites in Germany
- Volunteers
- 10 people
- Sponsor
- University of Jena
Colon Cancer Stage I, Colon Cancer Stage II
Comparison Between Results of 2 Laparoscopic Surgical Procedures in Operable Colon Cancer Cases in Upper Egypt
The investigators will assess and compare Surgical, pathological and oncological outcomes between two laparoscopic procedures conventional colectomy versus complete mesocolic excision for operable colon cancer cases in Upper Egypt
- Trial name
- NCT05421702
- Testing
- laparoscopic conventional colectomy, laparoscopic complete mesocolic excision
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Sohag University
Upper Gastrointestinal Bleeding
Safety & Efficacy of Omeprazole Sodium Bicarbonate for the Prevention of Upper GI Bleeding in the Critically Ill
Critically ill patients are at an increased risk of having upper gastrointestinal (GI) bleeding due to stress related mucosal damage.
- Trial name
- NCT00045799
- Testing
- Omeprazole sodium bicarbonate immediate release PWD/FS, Cimetidine IV
- Where
- 58 sites in United States
- Volunteers
- 354 people
- Sponsor
- Bausch Health Americas, Inc.
Upper Gastrointestinal Bleeding, Gastro Intestinal Bleeding
Pediatric Acute Gastrointestinal Bleeding Registry
The goal of this study is to identify significant clinical and laboratory risk factors in pediatric patients with significant upper gastrointestinal bleeding.
- Trial name
- TRIAGE (NCT03090945)
- Testing
- This is an obsevational cohort study
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- Boston Children's Hospital