Clinical trials: Upper Limb Spasticity
Cerebral Palsy
Comparative Effects of Myofascial Stretch and Contract-relax in Children With Spastic cp
Cerebral palsy (CP) is primarily a neuromotor disorder that affects the development of movement, muscle tone and posture.It is one of the three most common lifelong developmental disabilities, the other two being autism and…
- Trial name
- NCT06292507
- Testing
- MYOFASCIAL STRETCH, CONTRACT-RELAX TECHNIQUE
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
Spastic Cerebral Palsy (sCP)
Rhythmic Stabilization Versus Ball Balancing
Spastic Cerebral Palsy (CP) is the leading cause of upper motor neuron syndrome (UMN) in children. The primary factors contributing to motor behavior disorders in these children are impairments in motor control and muscle…
- Trial name
- NCT06673849
- Testing
- Rhythmic Stabilization, Ball Balancing
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Cerebral Palsy (CP), Diplegic Cerebral Palsy
Effect of Intensive Segmental Trunk Training on Upper Extremity Function and Seated Postural Stability in Children With Spastic Diplegic Cerebral Palsy
The goal of this randomized controlled trial is to evaluate whether intensive segmental trunk training (ISTT) can improve upper extremity function and seated postural stability in children aged 4-12 years with spastic diplegic…
- Conditions
- Cerebral Palsy (CP), Diplegic Cerebral Palsy, Trunk Mobility, Upper Extremity Function
- Trial name
- NCT07692087
- Testing
- Intensive Segmental Trunk Training, Standard Physical Therapy
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- University of Lahore
Cerebral Palsy, Cerebral Palsy, Spastic
Effects of Hand and Arm Bimanual Intensive Therapy Including Lower Extremity in Spastic Cerebral Palsy
Cerebral palsy (CP), particularly the spastic diplegic subtype, is characterized by motor impairments such as spasticity and mobility limitations.
- Trial name
- HABIT-ILE (NCT07253857)
- Testing
- GROUP -A , Hand and Arm Bimanual Intensive Therapy Including Lower Extremity, GROUP-B , Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Cerebral Palsy, Spastic, Cerebral Palsy, Dyskinetic
Functional Benefits of Multisite Surgery for the Upper Limb of Children With Cerebral Palsy
The aim of the study is to investigate the impact of individualized multisite neuro-orthopedic surgery of the upper limb in children with Cerebral Palsy on unilateral functional capacities and bimanual performance.
- Conditions
- Cerebral Palsy, Spastic, Cerebral Palsy, Dyskinetic, Infantile Hemiplegic Cerebral Palsy
- Trial name
- NCT04395729
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française
Upper Extremity Spasticity, Quadriplegic Cerebral Palsy
ICF-Based Evaluation of the Upper Extremity in Children With Quadriparetic Cerebral Palsy
Cerebral palsy (CP) is a neurodevelopmental disorder characterized by abnormalities in muscle tone, movement, and motor skills resulting from permanent, non-progressive damage to the developing brain before, during, or after…
- Trial name
- NCT06585397
- Testing
- Grup 1
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Acıbadem Atunizade Hospital
Cerebral Palsy, Upper Extremity Dysfunction
The Effect of Upper Extremity Strengthening on Functionality, Muscle Strength and Trunk in Children With Cerebral Palsy
Cerebral Palsy (CP) is an activity limitation, movement and posture deficiencies in early stage of life. In 80% of these children, upper extremity (UE) dysfunctions are observed, which leads to loss of quality of life, resulting…
- Conditions
- Cerebral Palsy, Upper Extremity Dysfunction, Upper Extremity Functions, Muscle Strength
- Trial name
- NCT05115695
- Testing
- traditional physiotherapy approach, muscle strengthening exercise/Proprioceptive Neuromuscular Facilitation (PNF)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Hemiplegia and/or Hemiparesis Following Stroke
Exercise to Improve Sleep and Quality of Life in Stroke Patients Receiving Botulinum Toxin Treatment
This study aimed to investigate the contribution of aerobic exercise programmes to improving sleep quality, quality of life, and functional status, alongside conventional rehabilitation, in stroke patients who had received…
- Trial name
- NCT07369453
- Testing
- Aerobic exercise training using a cycle ergometer
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Cerebral Palsy, Spastic, Cerebral Palsy
The Validity and Reliability of the Turkish Version of TASC and the Relationship Between SMC and Motor Functions
Selective motor control (SMC) impairment in children with cerebral palsy (CP) includes movement patterns dominated by flexor or extensor synergy affecting functional movements.
- Conditions
- Cerebral Palsy, Spastic, Cerebral Palsy, Cerebral Palsy Spastic Diplegia, Cerebral Palsy Quadriplegic
- Trial name
- NCT04231227
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Gazi University
Hemiplegic Cerebral Palsy
Effect of Extracorporeal Shock Wave and Peripheral Magnetic Stimulation on Spastic CP Children
Hypotheses: There will be an effect of radial extracorporeal shock wave therapy and peripheral magnetic stimulation on the following parameters, in children with spastic hemiplegia: Wrist flexors spasticity.
- Trial name
- NCT05607134
- Testing
- selected physical and occupational therapy program, Radial Extracorporeal Shock Wave, Peripheral magnetic stimulation
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Spastic Cerebral Palsy
INcobotulinumtoxina in ChIldren Upper and Lower Limb sPasticITy (INCIPIT)
Prospective, open-label, non-randomized, single-arm, dose titration, phase II study. The study will consist of three injection cycles. In each, an injection visit is followed by an observation period of 12 to 20 weeks.
- Trial name
- INCIPIT (NCT05340439)
- Testing
- IncobotulinumtoxinA 100 UNT [Xeomin]
- Volunteers
- 30 people
- Sponsor
- Universita di Verona
Cerebral Palsy
Whole Body Vibration in Rehabilitation of Spastic Cerebral Palsy
Spasticity is one of the most common features in children with cerebral palsy (CP) and is evident in the majority of CP types such as hemiplegia, diplegia, quadriplegia, etc.
- Trial name
- WBV (NCT06077136)
- Testing
- whole body vibration, standard physical therapy
- Where
- Saudi Arabia
- Volunteers
- 56 people
- Sponsor
- University of Hail
Muscle Spasticity
The Efficacy and Safety of MEDITOXIN® in Children With Cerebral Palsy
The purpose of this study is to evaluate the efficacy and safety of Meditoxin® in the treatment of children with cerebral palsy.
- Trial name
- NCT01256021
- Testing
- Botulinum Toxin Type A
- Where
- 4 sites in South Korea
- Volunteers
- 212 people
- Sponsor
- Medy-Tox
Cerebral Palsy Spastic Hemiplegic
tSCS in Children and Young People With HCP
This work will examine if a technique called Transcutaneous Spinal cord stimulation (tSCS), when used with concurrent specific arm and hand exercises, helps improve arm and hand movements in CYP with HCP.
- Trial name
- NCT07247812
- Testing
- Digimer DS8R
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- University of Leeds
Cerebral Palsy (CP)
Constraint-induced Movement Therapy Combined With Functional Electrical Stimulation in Children With Cerebral Palsy
This randomized controlled trial aims to compare the effectiveness of Constraint-Induced Movement Therapy (CIMT) combined with Functional Electrical Stimulation (FES) versus CIMT alone in improving upper limb function, reducing…
- Trial name
- CIMT-FES-CP (NCT07587476)
- Testing
- Constraint-Induced Movement Therapy Combined with Functional Electrical Stimulation, Constraint-Induced Movement Therapy
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Montiha Azeem
Cerebral Palsy Spastic Diplegia
Neck-Trunk Stabilization Exercises and Bobath Therapy Spastic Diplegic Cerebral Palsy
Physiotherapy is widely used in the treatment of children with cerebral palsy. This study is conducted to identify the most appropriate physiotherapy approach.
- Trial name
- NCT05707052
- Testing
- Neck-Trunk Stabilization Exercises and conventional physical therapy, Bobath Therapy and conventional physical therapy
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Cerebral Palsy, Muscle
How Are the Muscles Affected in Cerebral Palsy? A Study of Muscle Biopsies Taken During Orthopaedic Surgery.
Cerebral palsy (CP) is a motor disorder caused by an injury to the immature brain. Even though the brain damage does not change, children with CP will have progressively weaker, shorter and stiffer muscles that will lead to…
- Conditions
- Cerebral Palsy, Muscle, Muscle Contracture, Muscle Spasticity
- Trial name
- CPTDBiopsy (NCT05506228)
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Eva Ponten
Cerebral Palsy
Task Oriented Activities Based on NDT Therapy Principles
Cerebral palsy (CP) is one of the primary causes of disability effecting majority of pediatric population. Cerebral Palsy is considered a neurological disorder caused by a non-progressive brain injury or malformation that occurs…
- Trial name
- NCT05903729
- Testing
- Neurodevelopmental therapy treatment, conventional physiotherapy
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Cerebral Palsy, Upper Extremity Paresis
Effectiveness of Armeo Spring Robotic Therapy in the Function of the Upper Limb of Children With Unilateral Spastic Cerebral Palsy Infiltrated With Botulinum Toxin
Background: Unilateral spastic cerebral palsy (CP) generates an impact on daily activities, mainly due to the functional limitation of the affected upper limb.
- Trial name
- NCT04554238
- Testing
- Armeo spring, Occupational Therapy
- Where
- Chile
- Volunteers
- 23 people
- Sponsor
- Sociedad Pro Ayuda del Niño Lisiado
Lower Limb and Combined Lower Limb and Upper Limb Spasticity Due to Cerebral Palsy
Long-term Open-label Study of Botulinumtoxin Type A to Treat Spasticity of Leg(s) or Leg(s) and Arm in Cerebral Palsy
The purpose of this study is to determine whether injections of Botulinum toxin type A into muscles of the leg(s) or of leg(s) and one arm are safe in treating children/adolescents (age 2-17 years) long-term with increased muscle…
- Trial name
- NCT01905683
- Testing
- IncobotulinumtoxinA (16-20 Units per kg body weight)
- Where
- 43 sites in Austria, Czechia and 10 more
- Volunteers
- 370 people
- Sponsor
- Merz Pharmaceuticals GmbH