Clinical trials: Upper Respiratory Infection
Recurrent Upper and Lower Respiratory Tract Infections (RTIs)
Prevention of Respiratory Infections and MAnagement Among Children (PRIMAKid)
The PRIMAKid trial is a general practice based double-blind randomized placebo-controlled trial on the effectiveness and costs of combined influenza and pneumococcal vaccination in pre-school children with recurrent respiratory…
- Trial name
- NCT00161122
- Testing
- trivalent inactivated influenza vaccine, combined heptavalent pneumococcal conjugate vaccine and trivalent inactivated influenza vaccine
- Where
- Netherlands
- Volunteers
- 660 people
- Sponsor
- UMC Utrecht
Respiratory Disease, Acute Respiratory Infection
Dialogue Around Respiratory Illness Treatment
Unwarranted use of antibiotics for pediatric acute respiratory tract infections (ARTIs) and use of second-line, broad spectrum antibiotics for bacterial ARTIs has contributed to the rapid development of resistance in many strains…
- Conditions
- Respiratory Disease, Acute Respiratory Infection, Respiratory Infection, Upper Respiratory Infection
- Trial name
- DART (NCT02943551)
- Testing
- Online Tutorial, Webinars, Booster Sessions
- Where
- 20 sites in United States
- Volunteers
- 2,728 people
- Sponsor
- Seattle Children's Hospital
Cough
Efficacy and Safety of Rengalin in the Treatment of ARVI Cough in Children
The goal of this clinical trial is to evaluate the efficacy and safety of liquid dosage form of Rengalin in the treatment of cough in acute viral upper respiratory tract infections infections in children in during the epidemic…
- Trial name
- NCT07171099
- Testing
- Rengalin
- Where
- 30 sites in Russia
- Volunteers
- 264 people
- Sponsor
- Materia Medica Holding
Influenza-like Illness, Upper Respiratory Disease
Non-specific Effects of Rabies Vaccine
Vaccines work by stimulating the body to produce a high-quality, rapid and specific immune response upon exposure to infection by a particular disease-causing microorganism - the microorganism targeted by the vaccine.
- Conditions
- Influenza-like Illness, Upper Respiratory Disease, Diarrhea, Fever
- Trial name
- NCT03656198
- Testing
- Rabivax-S, Sterile Water Injection
- Where
- Saint Kitts and Nevis
- Volunteers
- 546 people, healthy volunteers welcome
- Sponsor
- Ross University School of Veterinary Medicine
Respiratory Failure, Bronchiolitis
Using HFNC in Bronchiolitis
The investigators compared oxygen therapy using the HFNC and diffuser mask (an effective low-flow oxygen delivery system) to treat patients with moderate-to-severe acute bronchiolitis admitted to an intensive care unit (ICU).
- Trial name
- NCT03342781
- Testing
- high flow nasal oxygen therapy, Diffuser oxygen mask
- Volunteers
- 60 people
- Sponsor
- Kayseri Training and Research Hospital
Hypothermia
Hypothermia in the Trauma Patient - When do Trauma Patients Get Cold?
The purpose of this study is to analyze changes in core body- and skin temperature during pre-hospital and early in-hospital treatment of multi-traumatized patients.
- Trial name
- NCT01006837
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Norwegian University of Science and Technology
Upper Respiratory Tract Infection, Bacterial Infection
Qingfei Granule for the Treatment of the Pediatric Acute Upper Respiratory Tract Infection With Bacterial Infection
The study aims to assess the antibacterial effect and symptoms-relief of Qingfei Granule in the patients with pediatric acute upper respiratory tract infection with bacterial infection.
- Conditions
- Upper Respiratory Tract Infection, Bacterial Infection, Chinese Medicine, Pediatric Acute Upper Respiratory Tract Infection
- Trial name
- NCT04479657
- Testing
- QingFei Granule, Cefuroxime
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Zhong Wang
Obesity, Obesity, Abdominal
Environmental Temperature and Human White Adipose Tissue
Obesity is characterized by excessive white adipose tissue (WAT) that increases risk for disease. About 700 million adults are obese worldwide, designating the need of reducing excessive WAT in humans and subsequently the risk…
- Conditions
- Obesity, Obesity, Abdominal, Obese
- Trial name
- NCT04037371
- Testing
- Cold exposure
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Petros Dinas
Pediatric Acute Upper Respiratory Tract Infection, Pediatric
The Effect of Using Distractor Cards and Thermochromic Cards on Pain, Fear, Anxiety and Procedure Time in Children Receiving Inhaler Therapy
THE EFFECT OF USİNG DİSTRACTOR CARDS AND THERMOCHROMİC CARDS ON PAİN, FEAR, ANXİETY AND PROCEDURE TİME İN CHİLDREN RECEİVİNG INHALER THERAPY.
- Conditions
- Pediatric Acute Upper Respiratory Tract Infection, Pediatric, Pediatric Acute Respiratory Failure
- Trial name
- CALM-INH (NCT07371026)
- Testing
- thermochromic card, distraction card
- Volunteers
- 90 people
- Sponsor
- Muhammed Ata Nur GEÇER
Upper Respiratory Infections
Effects of Echinacea in Children
The goal of the this study is to determine if Echinacea purpurea stimulates the immune system in children. For the study, 40 healthy children, 6-11 years old will be randomized to receive Echinacea purpurea or placebo for 10 days…
- Trial name
- NCT00773435
- Testing
- Echinacea purpurea 100 mg/ml in liquid formulation
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Washington
Nasal Congestion Associated With the Common Cold
A Multicenter Study of Pseudoephedrine for the Temporary Relief of Nasal Congestion in Children With the Common Cold
This study is designed to confirm the effectiveness of single-ingredient pseudoephedrine in children for the temporary relief of nasal congestion due to the common cold, an indication described under 21 CFR 341.80(b)(1).
- Trial name
- NCT01744106
- Testing
- pseudoephedrine hydrochloride 30 mg tablets
- Where
- 11 sites in United States
- Volunteers
- 565 people
- Sponsor
- Perrigo Company
Anesthesia, Endotracheal
The Effects of Beclomethasone Upper the Endotracheal Cuff on the Occurrence of Sore Throat at Extubation
The aim of the study is to test the effectiveness of a solutions of beclomethasone repeatedly instilled through the supraglottic line of the endotracheal tube on post-extubation airway disturbances related to tracheal intubation.
- Trial name
- BEnTS (NCT02687100)
- Testing
- Beclomethasone
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Tonsillitis
Outcomes of Bipolar Electrocautery Tonsillectomy Versus Cold Steel Dissection Pediatric Tonsillectomy
It was intended to practically establish whether or not the relatively newer technique of tonsillectomy like bipolar electrocautery tonsillectomy has any added benefits in reducing the duration of surgery, blood loss and…
- Trial name
- NCT06494839
- Testing
- Bipolar electrocautery tonsillectomy technique, Cold steel dissection technique
- Where
- Pakistan
- Volunteers
- 110 people
- Sponsor
- RESnTEC, Institute of Research
Healthy
Trial to Assess Safety, Tolerability, and Immunogenicity of Influenza Virus Vaccine, Trivalent, Types A and B, Live Cold-adapted (CAIV-T) in Healthy Children
The study was designed to determine the number of doses of CAIV-T required to effectively immunize children and adolescents in the 6 to 17 year age group.
- Trial name
- FluMist (NCT00192270)
- Testing
- CAIV-T
- Where
- 3 sites in Belgium, Finland
- Volunteers
- 498 people, healthy volunteers welcome
- Sponsor
- MedImmune LLC
Acute Upper Respiratory Tract Infections, Nasal Obstruction
Influence of Patient Positioning During Nasal Lavage
Acute upper respiratory tract infections are the primary cause of pediatric visits and hospitalizations in young children. Nasal congestion and mucus accumulation often cause discomfort, feeding difficulties, and respiratory…
- Conditions
- Acute Upper Respiratory Tract Infections, Nasal Obstruction, Bronchiolitis
- Trial name
- nasal lavage (NCT07921680)
- Testing
- Supine position nasal lavage, Semi-sitting position nasal lavage
- Where
- Spain
- Volunteers
- 145 people
- Sponsor
- Hospital Universitario La Paz
Upper Respiratory Tract Infections
Reducing Unnecessary Antibiotic Prescriptions in Primary Healthcare in Saskatchewan by Identifying High Prescribers
Approximately 90% of antibiotics are prescribed in primary healthcare (PHC) in Canada (Public Health Agency of Canada, 2020), making this an important sector for antimicrobial stewardship.
- Trial name
- NCT05557214
- Testing
- Audit and Feedback Letter
- Volunteers
- healthy volunteers welcome
- Sponsor
- Saskatchewan Health Authority - Regina Area
Influenza, Human, Acute Respiratory Infection
Efficacy and Safety of Ingavirin®, Syrup, 30 mg/5 ml, in Children With Influenza and Other Acute Respiratory Viral Infections
The study is planned to evaluate the therapeutic efficacy and safety of Ingavirin®, syrup, 30 mg/5 ml, in the treatment of influenza or other acute respiratory infections in children from 6 months to 2 years compared with placebo.
- Conditions
- Influenza, Human, Acute Respiratory Infection, Common Cold
- Trial name
- NCT05269290
- Testing
- Ingavirin®, syrup, 30 mg/5 ml
- Where
- 8 sites in Russia
- Volunteers
- 240 people
- Sponsor
- Valenta Pharm JSC
Cough
Transpulmin Suppository and Guaiacol Compared to Transpulmin Syrup in Pediatric Participants With Productive Cough
This study evaluates the non-inferiority of Suppository Transpulmin and Suppository Guaiacol compared to Transpulmin Syrup in the treatment of cough with secretion of infectious origin in children between two and six years old.
- Trial name
- Transpulmin (NCT02581397)
- Testing
- Transpulmin suppository, Guaiacol suppository, Transpulmin syrup
- Where
- Brazil
- Volunteers
- 270 people
- Sponsor
- Ache Laboratorios Farmaceuticos S.A.
Pneumonia, Bronchiolitis
Diagnosing Respiratory Disease in Children Using Cough Sounds
The purpose of this prospective study is to evaluate the efficacy of the ResAppDx software application in diagnosis of pneumonia and other respiratory conditions (bronchiolitis, asthma/reactive airway disease, croup, upper or…
- Conditions
- Pneumonia, Bronchiolitis, Asthma, Croup
- Trial name
- SMARTCOUGH-C (NCT02973282)
- Testing
- Recording of Infants and Children's Cough Sounds
- Where
- 3 sites in United States
- Volunteers
- 1,245 people
- Sponsor
- ResApp Health Limited