Clinical trials: Urinary Tract Obstruction
Urologic Neoplasms
Antegrade Double-J Stent Placement for the Treatment of Malignant Obstructive Uropathy
Ureteral double- J stent is usually inserted by retrograde approach for the treatment of obstructed upper urinary tract. The antegrade approach, can a suitable alternative in certain situations without the need for general or…
- Trial name
- NCT04649970
- Testing
- Antegrade double-J stent
- Volunteers
- 174 people
- Sponsor
- Université de Sousse
Ureteropelvic Junction Obstruction, Chronic Kidney Diseases
The PRO-FUTURE Project
The goal of this observational study is to learn about specific biomarkers of unilateral ureteropelvic junction obstruction (UPJO) in children undergoing surgical intervention for unilateral UPJO compared with controls.
- Trial name
- PRO-FUTURE (NCT06382233)
- Testing
- Identification of Diagnostic Biomarkers
- Where
- 5 sites in Italy
- Volunteers
- 85 people
- Sponsor
- University of Campania Luigi Vanvitelli
Prostatic Neoplasm, Lower Urinary Tract Symptoms
Prostatic Artery Embolization for Obstructive Uropathy Due to Prostate Cancer
The aim of this study is to investigate the safety and efficacy of prostatic artery embolization of patients with recurrent symptoms secondary to locally advanced prostatic cancer including pelvic pain, bleeding or need for…
- Conditions
- Prostatic Neoplasm, Lower Urinary Tract Symptoms, Urological Manifestations, Prostatic Diseases
- Trial name
- NCT03104907
- Testing
- Prostatic Artery Embolization
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Benign Prostatic Hyperplasia (BPH), Lower Urinary Tract Symptom
A Prospective Comparative Study Evaluating the Safety and Efficacy of Transurethral Thulium Fiber Laser, Holmium Laser and Bipolar Enucleation of Large Sized Prostate
This study compares the safety and efficacy of three endoscopic enucleation techniques for large prostates (>100 mL) in patients with benign prostatic hyperplasia (BPH): Thulium Fiber Laser Enucleation (ThuFLEP), Holmium Laser…
- Conditions
- Benign Prostatic Hyperplasia (BPH), Lower Urinary Tract Symptom, Bladder Outlet Obstruction
- Trial name
- NCT07627178
- Testing
- Thulium Fiber Laser Enucleation of the Prostate (ThuFLEP), Holmium Laser Enucleation of the Prostate (HoLEP), Bipolar Transurethral Enucleation of the Prostate (B-TUEP)
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tanta University
Pelviureteric Junction Obstruction, Pyeloplasty
Dismembered Pyeloplasty With and Without After Coming Stent
to compare outcome of pyeloplasty in pediatric population less than 6 months in age using an after coming stent versus stentless pyeloplasty.
- Conditions
- Pelviureteric Junction Obstruction, Pyeloplasty, Neonatal Hydronephrosis, Obstructive Uropathy
- Trial name
- NCT02138877
- Testing
- After coming stent after dismembered pyeloplasty, Stentless dismembered pyeloplasty
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Obstructive Uropathy
Ultrasonic Visualization of Obstructive Uropathies in Children
The purpose of this study was to develop proposals and recommendations for improving the safety of urological examination of children with obstructive uropathy by using Doppler ultrasound.
- Trial name
- NCT04605835
- Testing
- ULTRASONIC VISUALIZATION OF OBSTRUCTIVE UROPATHIES IN CHILDREN.
- Where
- Uzbekistan
- Volunteers
- 655 people
- Sponsor
- Samarkand State Medical Institute
Urethral Obstruction
Fetal Cystoscopy for Lower Urinary Tract Obstruction
This is a pilot study to evaluate the safety, feasibility, and effectiveness of fetal cystoscopy as an experimental procedure in avoiding perinatal death and renal impairment and to compare to the investigators clinical…
- Trial name
- NCT02446184
- Testing
- Fetal Cystoscopy, Fetal vesicoamniotic shunt
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Baylor College of Medicine
Urethral Obstruction
Standardized Prenatal Clinical Care for LUTO
The investigators propose a standardized prenatal management, based on the scientific evidence published in the literature, to manage prenatally fetuses with lower urinary tract obstruction (LUTO).
- Trial name
- NCT02315521
- Testing
- Fetal Intervention for LUTO
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Baylor College of Medicine
Neurogenic Bladder, Neurogenic Bowel
The Role of Active Administration of Peristeen Bowel Evacuation for the Management of Urinary Tract Infection
This study investigates whether active use of transanal irrigation (Peristeen®) effectively manages urinary tract infection among patients with the diagnosis of neurogenic bladder.
- Conditions
- Neurogenic Bladder, Neurogenic Bowel, Spina Bifida, Fecal Incontinence
- Trial name
- NCT04815226
- Testing
- Peristeen Transanal Irrigation
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Hyperplasia Prostatic, Lower Urinary Tract Symptoms
Prostatic Artery Embolization for Benign Prostatic Obstruction
The aim of this study is to investigate the safety and efficacy of prostatic artery embolization (PAE) for patients who refuse or are not eligible for surgery with moderate-severe lower urinary tract symptoms or indwelling…
- Conditions
- Hyperplasia Prostatic, Lower Urinary Tract Symptoms, Prostatic Diseases, Urological Manifestations
- Trial name
- NCT03099421
- Testing
- Prostatic Artery Embolization
- Where
- Denmark
- Volunteers
- 11 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Urinary Tract Obstruction
A Comparative Study of Normalized Residual Activity and Standard Parameters in 99mTc-DTPA Diuretic Renography:
The present study aims to compare the diagnostic performance of Normalized Residual Activity (NORA) with conventional renographic parameters obtained from 99mTc-diethylenetriamine pentaacetic acid (99mTc-DTPA) diuretic renography…
- Trial name
- NCT07811388
- Testing
- 99m Tc-DTPA, Furosemide
- Volunteers
- 57 people
- Sponsor
- Assiut University
Congenital Anomalies of Kidney and Urinary Tract, Lower Urinary Tract Obstruction, Congenital
Ultrasound Localization Microscopy in Patient With Congenital Anomalies of the Kidney and Urinary Tract (CAKUT)
This clinical study aims to non-invasively visualize perfusion and microvascularization, as well as individual glomeruli, using Ultrasound Localization Microscopy (ULM) and CEUS in patients with congenital anomalies of the kidney…
- Conditions
- Congenital Anomalies of Kidney and Urinary Tract, Lower Urinary Tract Obstruction, Congenital, Ureteropelvic Junction Obstruction, Hydronephrosis Congenital
- Trial name
- Search_CAKUT (NCT06921733)
- Testing
- Contrast enhanced ultrasound imaging (CEUS) and post processing with ULM
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Lower Urinary Tract Obstructive Syndrome
Fetal Cystoscopy Versus Vesico-amniotic Shunting in Severe Lower Urinary Tract Obstructions
There are two options of fetal treatment in cases of severe lower urinary tract obstructions: the vesico-amniotic shunting and fetal cystoscopy.
- Trial name
- CYSTUO (NCT01552824)
- Testing
- CYSTO, Vesico-amniotic shunt
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo General Hospital
Acute Renal Failure, Anuria
Delayed or Direct Ureteroscopy in the Treatment of Pediatric Calcular Anuria
To compare staged ureteroscopy following initial urinary drainage versus direct ureteroscopy without initial urinary drainage in the treatment of obstructive calcular anuria with acute renal failure in children.
- Conditions
- Acute Renal Failure, Anuria, Obstructive Uropathy, Ureteric Stones
- Trial name
- NCT02139059
- Testing
- initial urinary drainage, direct ureteroscopy
- Where
- 2 sites in Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Urinary Tract Infection, Kidney Diseases
A Randomized Control Trial Comparing Single vs. Multiple Application of Lidocaine Analgesia Prior to Urethral Catheterization Procedures
The purpose of this study is to determine if a single application of Lidocaine gel topical anesthesia is as effective in decreasing the discomfort associated with urinary catheterization as two applications, within our pediatric…
- Conditions
- Urinary Tract Infection, Kidney Diseases, Ureteral Diseases, Ureteral Obstruction
- Trial name
- NCT00142064
- Testing
- observed levels of pain
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Benign Prostatic Hyperplasia With Lower Urinary Tract Symptoms
Registry of MIUS for Benign Prostatic Obstruction
This national, multicenter, prospective registry aims to collect standardized perioperative and follow-up data on patients undergoing minimally invasive surgical management for benign prostatic obstruction (BPO) in Turkey.
- Trial name
- ReMIUS-BPO (NCT07159165)
- Testing
- Minimally invasive surgical treatment for benign prostatic obstruction
- Where
- Turkey (Türkiye)
- Volunteers
- 10,000 people
- Sponsor
- Ondokuz Mayıs University
Renal Failure Congenital, Congenital Renal Anomaly Nos
Serial Amnioinfusions as Regenerative Therapy for Pulmonary Hypoplasia
Congenital lower urinary tract obstruction (LUTO) is a heterogeneous group of congenital anomalies that lead bladder outlet obstruction.
- Conditions
- Renal Failure Congenital, Congenital Renal Anomaly Nos, Renal Agenesis and Dysgenesis, Lower Urinary Tract Obstructive Syndrome
- Trial name
- NCT03723564
- Testing
- Lactated Ringers Solution for Injection
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Ureteral Obstruction, Neoplasms
Antibiotic Prophylaxis in Percutaneous Nephrostomy Placements and Replacements for Malignant Urinary Tract Obstruction
This study aims to find out whether taking antibiotics to prevent a urinary tract infection after a medical procedure called percutaneous nephrostomy (placement of a catheter directly into the kidney to keep it working after the…
- Conditions
- Ureteral Obstruction, Neoplasms, Acute Kidney Injury, Nephrostomy; Complications
- Trial name
- NCT06801405
- Testing
- antibiotic prophylaxis
- Where
- Brazil
- Volunteers
- 320 people
- Sponsor
- Barretos Cancer Hospital
Ureteral Obstruction
Functional MR Urography
The objective of functional Uro MR is to add to an initial morphological phase, based on T2 and T1 weighted MR sequences, a sequential contrast-enhanced acquisition allowing to obtain functional semi-quantitative parameters from…
- Trial name
- NCT00301470
- Testing
- MR urography
- Where
- 16 sites in France
- Volunteers
- 550 people
- Sponsor
- Central Hospital, Nancy, France
Urolithiasis, Urologic Diseases
Effectiveness of Drainage by PCN vs. JJ in Patients With Symptoms of Obstructive Kidney Disease Caused by Urolithiasis
To investigate the effectiveness of percutaneous nephrostomy catheter placement versus retrograde double J catheter placement in patients with symptoms of obstructive kidney disease (with either infection and/or pain and/or…
- Conditions
- Urolithiasis, Urologic Diseases, Urinary Calculi, Urinary Obstruction
- Trial name
- STONE (NCT04594161)
- Testing
- Percutaneous Nephrostomy, Double J catheter
- Where
- Netherlands
- Volunteers
- 204 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)