Clinical trials: Urination Disorders
Human Papilloma Virus Infection
Standard Operating Procedures for Anti-HPV (Human Papillomavirus) Antibody Detection in First-void Urine
The aim of the study is to develop and implement robust analytical protocols for first-void urine sample preparation and antibody assays to monitor vaccine induced immunity against HPV (Human Papillomavirus).
- Trial name
- ABSOP-FollowUp (NCT03542227)
- Testing
- First-void urine collection, Blood draw
- Where
- Belgium
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
Normal Pressure Hydrocephalus
Effect of Depletive Lumbar Puncture on Lower Urinary Tract Dysfunction in iNPH
Lower urinary tract dysfunction in normal pressure hydrocephalus has received little attention from the scientific community. Urinary symptoms in normal pressure hydrocephalus are mainly represented by overactive bladder, which…
- Trial name
- PLHPN (NCT03877107)
- Testing
- Urinary symptoms profile questionnaire, Micturition calendar
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- EssaiClinique_PL-HPN
Proteinuria, Chronic Kidney Diseases
Efficacy and Safety of Dapagliflozin in Children With Proteinuric Chronic Kidney Disease
We aim to investigate the antiproteinuric effect of adding Dapagliflozin to the standard of care in children with proteinuria.
- Trial name
- NCT04531397
- Testing
- ACEI treatment, Dapagliflozin+ACEI treatment
- Where
- China
- Sponsor
- Children's Hospital of Fudan University
Urinary Incontinence in Children
Strategy for Withdrawal of Pharmacological Treatment for Urinary Incontinence in Children (StayDry)
The primary objective is to investigate if abrupt withdrawal versus gradual withdrawal of pharmacotherapy (solifenacin and/or mirabegron) influences the risk of recurrence of incontinence.
- Trial name
- NCT06465576
- Testing
- Solifenacin, Mirabegron, Solifenacin + Mirabegron
- Where
- 5 sites in Denmark
- Volunteers
- 216 people
- Sponsor
- University of Aarhus
Hematuria, Hematospermia
The Use of Finasteride to Reduce Hematuria and Hematospermia Following TRUS Prostate Biopsy
The purpose of our study is primarily to evaluate the effects of 5mg finasteride on hematuria and hematospermia commonly associated with prostate biopsies.
- Trial name
- NCT00600691
- Testing
- Finasteride
- Where
- 2 sites in Canada
- Volunteers
- 29 people
- Sponsor
- University of British Columbia
Dysfunctional Voiding, Stress Incontinence, Urinary
Case Control Study to Investigate the Use of Urethral Pressure Profile Measurement in Children
The bladder has a muscle that acts like a tap called the sphincter. Just like a tap, when pee is stored the sphincter muscle is closed and during peeing the sphincter opens.
- Trial name
- NCT04147793
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- King's College London
Stress Urinary Incontinence (SUI), Postmenopausal Women
The Effectiveness of Combined Pelvic Floor Muscle Training and Vaginal Oestrogen Therapy in Postmenopausal Women With Stress Urinary Incontinence
The objective of this clinical trial is to investigate whether the combination of pelvic floor muscle training (PFMT) and topical estrogen is more effective in treating stress urinary incontinence (SUI) in postmenopausal women…
- Trial name
- NCT07186985
- Testing
- Combined Pelvic Floor Muscle Training and Vaginal Oestrogen Therapy, Vaginal estrogen
- Volunteers
- 115 people
- Sponsor
- Hanoi Medical University
Ulcerative Colitis
Bleach and Urine Color in UC Patients Using 5ASA
The aim of this study is to evaluate the effect on urine color by adding household bleach to fresh urine sample among pediatric UC subjects treated with 5ASA
- Trial name
- Asableach (NCT06013696)
- Testing
- Adding household bleach to urine sample
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Meir Medical Center
Female Stress Urinary Incontinence
Effect Of Abdominal Hypopressive Training On Stress Urinary Incontinence
Fifty female athletes suffering from stress incontinence (SUI) will participate in this study. They will be selected from El Zohour Club, New Cairo City.
- Trial name
- NCT06599190
- Testing
- pelvic floor exercises, nutritional instructions, abdominal hypopressive exercises, pelvic floor exercises, nutritional instructions
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Badr University
Urinary Incontinence, Stress
Stress Urinary Incontinence of Sporting Teenager
Physical activity and sport are beneficial to the cardiovascular system, the musculoskeletal system and many chronic pathologies. The High Authority of Health (HAS) recommends a regular practice.
- Trial name
- INCREASE (NCT03309397)
- Where
- France
- Volunteers
- 103 people
- Sponsor
- University Hospital, Brest
Chronic Kidney Disease, Glomerulopathy
Clinical Phenotyping Resource and Biobank Core of the Michigan O'Brien Renal Center
Chronic kidney disease (CKD) affects approximately 26 million Americans and disproportionately manifests in specific race and ethnic groups. Patients burdened with CKD have significant morbidity and reduced life expectancy.
- Trial name
- C-PROBE (NCT01016613)
- Where
- 5 sites in United States
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Chronic Kidney Disease, Proteinuria
A Study to Learn More About How Well the Study Treatment Finerenone Works, How Safe it is, How it Moves Into, Through, and Out of the Body, and the Effects it Has on the Body When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker in Children With Chronic Kidney Disease and Proteinuria
Researchers are looking for a better way to treat children who have chronic kidney disease (CKD), which is long-term kidney disease, and proteinuria, a condition in which a person´s kidneys leak protein into the urine.
- Trial name
- FIONA (NCT05196035)
- Testing
- Finerenone (Kerendia, BAY94-8862)
- Where
- 132 sites in United States, Argentina and 30 more
- Volunteers
- 219 people
- Sponsor
- Bayer
Urinary Catheters, Retention, Urinary
Evaluation of a Novel Medical Device to Facilitate Gel Instillation During Change of Long-term Urinary Catheters
A randomized, open label, controlled, parallel group study to investigate difference between regional standard procedure and a novel modified procedure (using an additional novel device to facilitate gel installation) for…
- Conditions
- Urinary Catheters, Retention, Urinary, Incontinence, Urinary, Anesthesia, Local
- Trial name
- NCT03289117
- Testing
- Novel gel installation device procedure, Standard procedure
- Where
- Sweden
- Volunteers
- 32 people
- Sponsor
- Region Skane
Urinary Incontinence,Stress, Urinary Incontinence, Urge
Tension-free Vaginal Tape Obturator for the Treatment of Urinary Incontinence -Long-term Follow-up
The efficacy of TVT-O (tension-free vaginal tape obturator) is well established in patients with stress urinary incontinence (SUI).
- Trial name
- NCT04240613
- Testing
- TVT-O
- Volunteers
- 106 people
- Sponsor
- Turku University Hospital
Proteinuria
Availability Study of ACTH to Treat Children SRNS/SDNS
Primary nephrotic syndrome(NS) is a common children renal disease.About 20% primary nephrotic syndrome are steroid-dependent and steroid-resistant.Low serum cortisol is one of the main relapse reasons.Adrenocorticotropic…
- Trial name
- NCT02972346
- Testing
- ACTH
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Incontinence, Urinary, Enuresis, Nocturnal
Alarm Treatment for Combined Enuresis and Daytime Urinary Incontinence in Children
The aim is to examine whether alarm therapy in addition to urotherapy can have a beneficial effect in treating urinary incontinence children with combined daytime incontinence and enuresis.
- Conditions
- Incontinence, Urinary, Enuresis, Nocturnal, Enuresis
- Trial name
- ABDE (NCT04260646)
- Testing
- Enuresis Alarm Rodger and Timer watch (Rodger), Timer watch (Rodger)
- Where
- 4 sites in Denmark
- Volunteers
- 89 people
- Sponsor
- Aalborg University Hospital
Urologic Diseases, Urogenital Disease
VR to Reduce Pain and Anxiety During GU Scans
This study aims to test the effectiveness of virtual reality (VR) in reducing pain and anxiety in children undergoing voiding cystourethrograms (VCUG) at Children's Hospital Los Angeles (CHLA).
- Conditions
- Urologic Diseases, Urogenital Disease, Vesico-Ureteral Reflux
- Trial name
- NCT04251988
- Testing
- Oculus Go VR
- Where
- United States
- Volunteers
- 410 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Urination Disorders
Pharmacokinetics, Safety and Tolerability of Tamsulosin Hydrochloride in Children With Voiding Disorders
To investigate pharmacokinetics, safety, and tolerability of tamsulosin hydrochloride in children with voiding disorders
- Trial name
- NCT02266524
- Testing
- Tamsulosin hydrochloride, very low dose, Tamsulosin hydrochloride, low dose, Tamsulosin hydrochloride, medium dose
- Volunteers
- 48 people
- Sponsor
- Boehringer Ingelheim
Leukemia, Acute Lymphocytic (ALL), Leukemia, Myeloid, Acute(AML)
Haploidentical Stem Cell Transplantation for Patients With Hematologic Malignancies
Blood and marrow stem cell transplant has improved the outcome for patients with high-risk hematologic malignancies. However, most patients do not have an appropriate HLA (immune type) matched sibling donor available and/or are…
- Conditions
- Leukemia, Acute Lymphocytic (ALL), Leukemia, Myeloid, Acute(AML), Leukemia, Myeloid, Chronic(CML), Juvenile Myelomonocytic Leukemia(JMML)
- Trial name
- NCT00186823
- Testing
- Miltenyi Biotec CliniMACS, Stem Cell Transplantation, TBI, systemic chemotherapy and antibodies as follows:
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- St. Jude Children's Research Hospital
Urinary Retention Postoperative
The Effect of Playing the Sound of Water and Watching Videos With VR on Urination, Fear, and Pain in Post-Op Children
It was aimed to investigate the effects of watching a video with water sound via virtual reality and listening to the sound of water through headphones on urination, fear and pain in children in the post-operative period.
- Trial name
- NCT07304583
- Testing
- Listening to the sound of water
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people
- Sponsor
- Ondokuz Mayıs University