Clinical trials: Urine
Bladder Cancer
Urine-based Detection of Non-muscle Invasive Bladder
Non-muscle invasive bladder cancer (NMIBC), which comprises approximately 75% of bladder tumors, has the highest recurrence rate of all cancers, with around 70% of the patients developing local recurrences, despite elaborated…
- Trial name
- SOLUSION (NCT03962933)
- Where
- Denmark
- Volunteers
- 196 people
- Sponsor
- Nessn Azawi
Idiopathic Infantile Hypercalcaemia - Severe Form, Genetic Disease
Rifampin in CYP24A1-related Hypercalcemia and Hypercalciuria
This study evaluates the efficacy of rifampin in the treatment of hypercalcemia and/or hypercalciuria in participants with at least one inactivating mutation of the CYP24A1 gene.
- Conditions
- Idiopathic Infantile Hypercalcaemia - Severe Form, Genetic Disease, Hypercalcemia, Idiopathic, of Infancy, Hypercalciuric Hypercalcemia
- Trial name
- RICHH (NCT03301038)
- Testing
- Rifampin
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Children's Hospital of Philadelphia
Urethral Meatal Stenosis
The Improvement in Uroflow and Postvoid Residual Urine After Urethral Meatotomy in Children With Meatal Stenosis
The improvement in uroflow and postvoid residual urine in children after urethral meatotomy for meatal stenosis. The hypothesis is that there is an improvement in both parameters, thus justifying the procedure.
- Trial name
- NCT01214525
- Where
- Israel
- Volunteers
- 25 people
- Sponsor
- Meir Medical Center
Cocaine-Related Disorders
Cocaine in Parotid Saliva, Blood and Urine - 4
The purpose of this study is to establish the use of parotid saliva as a means of detecting and quantifying cocaine and its metabolites.
- Trial name
- NCT00000190
- Testing
- Parotid Gland
- Where
- United States
- Sponsor
- University of Pennsylvania
Urine Specimen Collection
The Effect of Non-invasive Bladder Stimulation Technique on Collecting Urine Specimen in Infants Under One Year Old
Urinary tract infection (UTI) is common in early childhood. The American Academy of Pediatrics accepts suprapubic aspiration and bladder catheterization as the gold standard for the diagnosis of UTI.
- Trial name
- NCT05394454
- Testing
- Bladder stimulation technique
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Istanbul University - Cerrahpasa
Diabetes Mellitus, Type 1, Diabetes Mellitus
Urine Extracellular Vesicles: Non-invasive Biomarkers of Β-cell Function and Novel Therapeutic Agents in Diabetes
Diabetes mellitus is a common chronic disease with a huge socioeconomic burden worldwide. Type 1 Diabetes(T1D) accounts for nearly 95% of diabetes in pediatric age and a lifelong dependence on exogenous insulin.
- Trial name
- EvsBioDiabetes (NCT06832215)
- Testing
- Blood and urine samples collection
- Where
- Portugal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Unidade Local de Saúde de Coimbra, EPE
Prostate Cancer
Study of Tissue, Blood, and Urine Samples From Patients With Advanced Prostate Cancer
RATIONALE: Studying samples of tissue, blood, and urine from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT00967889
- Testing
- gene expression analysis, protein analysis, biologic sample preservation procedure
- Where
- United Kingdom
- Sponsor
- Cancer Research UK
Tuberculosis
Early Risk Assessment in Household Contacts (≥10 Years) of TB Patients by New Diagnostic Tests in 3 African Countries
The ERASE - TB study will be conducted in order to fill a critical unmet need for tuberculosis control. Persons who are in contact with an infectious TB case may become infected themselves.
- Trial name
- ERASE-TB (NCT04781257)
- Testing
- New test candidates
- Where
- 3 sites in Mozambique, Tanzania and 1 more
- Volunteers
- 2,100 people, healthy volunteers welcome
- Sponsor
- Michael Hoelscher
Urine Reflux, Kidney Damage
(ARFI) Shear Velocity Imaging of the Kidneys in Pediatric Patients
Urine reflux (urine backing up into the kidneys) is common in the pediatric population and may be complicated by renal abnormalities, such as infection and scarring.
- Trial name
- NCT01781819
- Testing
- ARFI SVI Ultrasound Imaging
- Where
- United States
- Sponsor
- University of Michigan
Preeclampsia, Proteinuria
Comparison of Catheterized and Clean Catch Urine Specimens for Protein/Creatinine Ratio in Preeclampsia Evaluation
The purpose of this prospective study was to examine whether protein/creatinine ratios in catheterized urine specimens correlate to clean catch specimens in pregnant patients being evaluated for preeclampsia.
- Conditions
- Preeclampsia, Proteinuria, Hypertension, Pregnancy
- Trial name
- UPREE (NCT00654771)
- Testing
- urine collection
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- University of Pittsburgh
Urinary Tract Infections in Children
Evaluation of Pain in Urinary Collections in Pediatric Emergencies in Children Who Have Not Acquired Cleanliness
Observational study.
- Trial name
- SONDAPU (NCT03263845)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Rennes University Hospital
Substance Abuse Detection
Optimizing Toxicological Screening in Drug Endangered Children
Background: Children who enter the foster care system are all too often exposed to illicit drugs in the home. Children from these homes, known as drug endangered children, are not routinely tested for harmful substances.
- Trial name
- NCT01037569
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Inborn Errors of Metabolism, Urea Cycle Disorder
Patient and Observer Reported Outcome Measurements in Inborn Errors of Metabolism
lnborn errors of metabolism (IEM) are a heterogeneous group of rare, sometimes debilitating or even fatal diseases . In IEM, both definition and assessment of meaningful outcome parameters is often extremely difficult resulting…
- Conditions
- Inborn Errors of Metabolism, Urea Cycle Disorder, Maple Syrup Urine Disease, Phenylketonurias
- Trial name
- MetaPROM (NCT04248062)
- Testing
- Survey
- Where
- Switzerland
- Volunteers
- 69 people
- Sponsor
- University Children's Hospital, Zurich
Chlamydia Infections, Gonorrhea
Prospective Collection of Female Specimens for Testing With Gen-Probe APTIMA (Registered Trademark) Assays
The objective of this study is to obtain female first-catch urine, vaginal, cervical and endocervical swabs for testing with multiple APTIMA Assays on the Gen-Probe PANTHER® and TIGRIS® Systems.
- Conditions
- Chlamydia Infections, Gonorrhea, Trichomonas Infections
- Trial name
- NCT01728103
- Testing
- APTIMA® Trichomonas vaginalis & APTIMA® COMBO 2® Assays
- Where
- 14 sites in United States
- Volunteers
- 1,336 people, healthy volunteers welcome
- Sponsor
- Gen-Probe, Incorporated
Cystinuria
TCUPS- Tolvaptan Use in Cystinuria and Urolithiasis: A Pilot Study
The goal of this research project is to establish that in short-term use, tolvaptan is a safe and potentially effective new therapy for cystinuria, by conducting a short-term pilot study of the safety and tolerability of this…
- Trial name
- TCUPS (NCT02538016)
- Testing
- Tolvaptan
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Caleb Nelson
Bladder Cancer, Urocystitis
A Multicenter Clinical Trial of Urine DNA Testing for Bladder Cancer in China
The primary objective of this study is to assess the safety and effectiveness of Human Multigene Methylation Detection Kit (Fluorescent PCR Method) for help diagnose bladder cancer by comparing with clinical standard method…
- Conditions
- Bladder Cancer, Urocystitis, Urinary Bladder Stone, Urothelial Carcinoma
- Trial name
- NCT05337189
- Testing
- Urine DNA methylation analysis, medical imaging and/or cystoscopy and/or pathological examination
- Where
- China
- Volunteers
- 482 people, healthy volunteers welcome
- Sponsor
- Creative Biosciences (Guangzhou) Co., Ltd.
Nocturnal Enuresis
The Effect of Melatonin on Nocturnal Enuresis
Aim: To investigate the effect of melatonin in bedwetting.
- Trial name
- NCT01575678
- Testing
- Melatonin, Lactose
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- University of Aarhus
Urinary Tract Infections
Bladder Stimulation Technique for Clean Catch Urine Collection in Infants
Urinary tract infection is the most common serious bacterial infection among infants. Bladder catheterization is considered the gold standard for diagnosis, yet is painful and invasive.
- Trial name
- NCT03174834
- Testing
- Bladder Stimulation technique
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Children's Hospital of Michigan
Iron Overload
The Iron Content of Ferritin in Serum and Urine of Children With High Serum Ferritin Levels
A serum ferritin level can reflect the total body iron content, thus a very low serum ferritin is commonly used as an indicator of iron deficiency and a very high serum ferritin is commonly used as a marker of iron overload.
- Trial name
- NCT03777904
- Testing
- Serum Ferritin level, Serum Ferritin iron content, Urine Ferritin level
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Utah
Urinary Tract Infection Bacterial
Evaluation of Urine Samples Obtained by Bladder Stimulation for the Diagnosis of Urinary Tract Infection in Infants
Urinary tract infection (UTI) is the most common serious bacterial infection among infants. Suprapubic aspiration and bladder catheterization are considered as the gold standard by the American Academy of Pediatrics for the…
- Trial name
- EEStiVeN (NCT03801213)
- Testing
- urinary catheterization, manual bladder stimulation technique
- Where
- 4 sites in France
- Volunteers
- 170 people
- Sponsor
- Fondation Lenval