Clinical trials: Uses
Esophageal Stricture
The Use of Triamcinolone Injection in Treatment of Refractory Benign Esophageal Stricture in Children
To evaluate the efficacy of Intra-lesional triamcinolone injection in the management of refractory benign esophageal Stricture in children.
- Trial name
- NCT04524897
- Testing
- Triamcinolone Injection in treatment of refractory benign Esophageal Stricture in children
- Volunteers
- 20 people
- Sponsor
- Assiut University
Underage Drinking, Alcohol Use, Underage
REAL Parenting Alcohol and Substance Use App
High school students' alcohol, nicotine, and marijuana use are major public health problems. Among the many consequences of these risky behaviors are impaired driving and impaired passenger fatalities as well as increased health…
- Trial name
- RP (NCT03932097)
- Testing
- REAL Parenting, Active Control Materials
- Where
- United States
- Volunteers
- 612 people, healthy volunteers welcome
- Sponsor
- Real Prevention, LLC
Well Being, Drug Addiction
Evaluation of Effectiveness of the LifeSkills Training - Lombardia - Primary Shool Program ( Val3P-LST )
Life Skills Training is a school-based prevention program aiming at promoting wellbeing and at preventig use of substances. It has a version for middle school and another for primary school students.
- Conditions
- Well Being, Drug Addiction, Tobacco Use, Alcohol Abuse
- Trial name
- Val3P-LST (NCT07858513)
- Testing
- life skills primary prevention
- Where
- Italy
- Volunteers
- 3,927 people, healthy volunteers welcome
- Sponsor
- Agenzia di Tutela della Salute della Città Metropolitana di Milano
CD55-deficient Protein-losing Enteropathy
Compassionate Use of Pozelimab
Provide compassionate use of pozelimab
- Trial name
- NCT05232110
- Testing
- Pozelimab
- Sponsor
- Regeneron Pharmaceuticals
Type 1 Diabetes Mellitus
Use of Continuous Glucose Sensors by Adolescents With Inadequate Diabetic Control
The incorporation of continuous glucose sensors (CGS) into management of type 1 diabetes in adolescence could improve treatment outcomes.
- Trial name
- CGM-Teens (NCT00945659)
- Testing
- Continuous Glucose Sensor, Standard Care, CGS + Behavior Therapy
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Nemours Children's Clinic
Acute Malnutrition in Childhood, Wasting
Treatment of Acute Malnutrition in Outpatient Care Services in Venezuela: a Prospective Cohort Research
The goal of this observational study is to compare the effectiveness, safety, and efficiency of the simplified protocol, which includes the following three modifications: a) use of a single treatment product (RUTF), b) reduced…
- Conditions
- Acute Malnutrition in Childhood, Wasting, Child Malnutrition
- Trial name
- NCT06287827
- Testing
- Simplified protocol, Standard protocol
- Where
- 4 sites in Venezuela
- Volunteers
- 299 people
- Sponsor
- UNICEF - Venezuela
Adolescent Cannabis Use Disorder
Biofeedback for Adolescent Cannabis Use Disorder
The aims of this study are: 1) to estimate the effect size of HRV biofeedback for stress in adolescents undergoing cognitive behavioral therapy (CBT) for cannabis use disorder (primary outcome: Perceived Stress Scale) and 2) to…
- Trial name
- NCT02059083
- Testing
- Heart rate variability biofeedback, CBT
- Sponsor
- Denver Health and Hospital Authority
Migraine Disorders
Special Drug Use Investigation for AMERGE® Tablet (Long-term)
To investigate the long-term safety and efficacy of AMERGE (naratriptan hydrochloride) on Japanese patients with migraine headache in clinical setting
- Trial name
- NCT01332383
- Testing
- Naratriptan
- Volunteers
- 300 people
- Sponsor
- GlaxoSmithKline
Cardiac Arrest, Needle Stick
Needle Stick Injuries in Emergency Medical Service Practice
During the pandemic era, medical personnel should wear full protective suits. However, they limit the performance of medical procedures. One of the main questions is whether to use double gloves.
- Conditions
- Cardiac Arrest, Needle Stick, Injuries, Glowe
- Trial name
- NCT04363788
- Testing
- double gloves
- Where
- Poland
- Volunteers
- 300 people
- Sponsor
- Lazarski University
CNS Tumor, Solid Tumor
INFORM2 Study Uses Nivolumab and Entinostat in Children and Adolescents With High-risk Refractory Malignancies
The aim of this trial is to determine preliminary activity of the combination treatment with nivolumab and entinostat in children and adolescents with high risk refractory/relapsed/progressive tumors harboring a high mutational…
- Trial name
- NCT03838042
- Testing
- Nivolumab and Entinostat
- Where
- 14 sites in Australia, Austria and 5 more
- Volunteers
- 91 people
- Sponsor
- University Hospital Heidelberg
Hypotension During Surgery, Blood Loss, Surgical
Reducing Hypotensive Anesthesia Use With TXA During Orthognathic Surgery
This prospective study will analyze the need for deliberate hypotensive anesthesia (DHA) during orthognathic surgery when tranexamic acid (TXA) is administered.
- Trial name
- NCT05474027
- Testing
- Avoidance of Deliberate Hypotensive Anesthesia, TRANEXAMIC ACID 1 G in 10 mL INTRAVENOUS INJECTION, SOLUTION
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Atopy, Allergic Disease
Use Cord Blood Single Nucleotide Polymorphism to Predict the Later Development of Atopy and Allergy
The aim of our study was firstly to detect in cord bloods the polymorphism of genes related to atopy and allergic diseases and to examine their mutual interaction and their associations with cord blood IgE and cytokines.
- Trial name
- NCT00444327
- Where
- 2 sites in Taiwan
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Min-Sheng General Hospital
Experimental Group: Smartphone Use Reduction, Control Group
Study Smart! Effectiveness of a Smartphone Use Intervention on Students' Performance and Well-being
Smartphone use in academic contexts (e.g., in lectures or while studying for an exam) appears to go along with negative effects on students' academic performance (i.e., concentration, perceived learning achievement, and grades)…
- Trial name
- NCT04550286
- Testing
- Smartphone Use Reduction in Academic Context, Control
- Where
- Germany
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Witten/Herdecke
Constipation
Methylnaltrexone Use for Opioid-induced Postoperative Constipation
The purpose of this study is to determine whether the routine use of methylnaltrexone in the post-operative pediatric spinal fusion patient will decrease the incidence of constipation.
- Trial name
- NCT01773096
- Testing
- Methylnaltrexone, Senna, docusate sodium, bisacodyl, magnesium hydroxide, Miralax
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Shriners Hospitals for Children
Granulomatosis With Polyangiitis (Wegener's), Granulomatosis With Polyangiitis
Abatacept for the Treatment of Relapsing, Non-Severe, Granulomatosis With Polyangiitis (Wegener's)
Multi-center, randomized, double-blind, placebo-controlled trial to evaluate the efficacy of abatacept to achieve sustained glucocorticoid-free remission in patients with relapsing non-severe granulomatosis with polyangiitis…
- Conditions
- Granulomatosis With Polyangiitis (Wegener's), Granulomatosis With Polyangiitis, Wegener's Granulomatosis, ANCA-Associated Vasculitis
- Trial name
- NCT02108860
- Testing
- Abatacept
- Where
- 20 sites in United States, Canada and 3 more
- Volunteers
- 65 people
- Sponsor
- University of South Florida
Isotretinoin, Isotretinoin Adverse Reaction
Expert Consensus on the Use of Isotretinoin in Acne Vulgaris: A Delphi Study
This study is a Delphi-based expert consensus project designed to establish evidence-informed, practical recommendations for the use of isotretinoin in acne vulgaris.
- Conditions
- Isotretinoin, Isotretinoin Adverse Reaction, Acne
- Trial name
- NCT07296523
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Venus Research Center
Intravenous Access
A Study to Evaluate SU-VEID™ for Improving Peripheral Venous Access Success in Children
The purpose of this study is to determine if use of the SU-VEID™ in children facilitates an increase success rate of peripheral intravenous starts, in comparison to the conventional method of vein entry techniques.
- Trial name
- NCT05204082
- Testing
- Single Use Vein Entry Indicator Device
- Where
- United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Cow's Milk Protein Allergy, Eosinophilic Gastrointestinal Disorders
A Study to Monitor the Use of an Amino Acid-Based Infant Formula
To assess the frequency and nature of adverse events in infants fed a free amino acid based infant formula.
- Conditions
- Cow's Milk Protein Allergy, Eosinophilic Gastrointestinal Disorders, Malabsorption/Maldigestion, Short Bowel Syndrome
- Trial name
- EAGLE (NCT02953223)
- Testing
- Free amino acid infant formula
- Where
- 29 sites in United States
- Volunteers
- 144 people
- Sponsor
- Société des Produits Nestlé (SPN)
Relationship, Family, Substance Use
Healthy Marriage and Responsible Fatherhood Grant Program With Phoenix House of New York
The purpose of this study is to provide a process and outcome evaluation of the HMRF grant-funded Connections program. Phoenix Houses of New York, Inc.
- Conditions
- Relationship, Family, Substance Use, Parenting
- Trial name
- HMRF-CP (NCT03640546)
- Testing
- Within My Reach/ Within Our Reach
- Where
- 3 sites in United States
- Volunteers
- 3,825 people, healthy volunteers welcome
- Sponsor
- Phoenix House Foundation, Inc.
Influenza
Drug Use Investigation for Arepanrix® (H1N1)
This post-marketing surveillance study is designed to collect safety information such as post-vaccination adverse events and adverse reactions from recipients of Arepanrix® (H1N1) Intramuscular Injection.
- Trial name
- NCT02069496
- Testing
- Arepanrix®
- Volunteers
- 3,405 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
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