Clinical trials: Uveitis, Intermediate
Uveitis
Psychosocial Outcomes and Transition Readiness in Uveitis
It is widely acknowledged that the transition from paediatric to adult health services should be a multidimensional and multidisciplinary process that addresses the medical, psychosocial, and educational needs of adolescents and…
- Trial name
- NCT03554824
- Where
- United Kingdom
- Volunteers
- 56 people
- Sponsor
- Sheffield Children's NHS Foundation Trust
Trematode Induced Granulomatous Uveitis
Vitrectomy Versus Suprachoroidal Steroid in Trematodal Granulomatous Uveitis
Presumed trematode-induced granulomatous intermediate uveitis (PTIGIU) presents with vitritis and complicated cataract (active stage) which, if left untreated, progresses to tractional retinal detachment (TRD) from the…
- Trial name
- NCT07105072
- Testing
- Vitrectomy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Minia University
Intermediate Uveitis, Posterior Uveitis
Retisert and Cataract Surgery in Patients With Severe Uveitis
To review chart data at the Duke Eye Center and determined whether a 3-year fluocinolone acetonide sustained drug delivery system (FA) safely suppressed postoperative inflammation when combined with phacoemulsification and…
- Trial name
- NCT00570830
- Testing
- Retisert (fluocinolone acetonide implant)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Duke University
Uveitis
Multicenter Uveitis Steroid Treatment (MUST) Trial
The purpose of this study is to compare the effectiveness of standardized systemic therapy versus fluocinolone acetonide implant therapy for the treatment of severe cases of non-infectious intermediate uveitis, posterior uveitis…
- Trial name
- MUST (NCT00132691)
- Testing
- fluocinolone acetonide intraocular implant, oral corticosteroid with immunosuppressive agents as needed
- Where
- 23 sites in United States, Australia and 1 more
- Volunteers
- 255 people
- Sponsor
- JHSPH Center for Clinical Trials
Uveitis, Posterior, Uveitis, Intermediate
A Study of LX211 in Clinically Quiescent Non-infectious Intermediate, Anterior and Intermediate, Posterior or Pan-Uveitis
The objective of this study is to evaluate the safety and efficacy of LX211 as therapy in subjects with clinically quiescent non-infectious uveitis
- Conditions
- Uveitis, Posterior, Uveitis, Intermediate, Panuveitis
- Trial name
- LUMINATE (NCT00404742)
- Testing
- LX211
- Where
- 41 sites in United States, Austria and 5 more
- Volunteers
- 232 people
- Sponsor
- Lux Biosciences, Inc.
Behcet's Disease, Uveitis
Immunogenetic Mechanisms in Behcet's Disease
Background: Uveitis, the inflammation of the interior of the eye, is responsible for numerous new cases of legal blindness every year.
- Trial name
- NCT01109433
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- National Eye Institute (NEI)
Juvenile Idiopathic Arthritis Associated Uveitis, Uveitis, Anterior
Adalimumab Dose Adjustment for Pediatric Uveitis Treatment Trial
The goal of this clinical trial is to learn whether children and young adults with well-controlled juvenile idiopathic arthritis (JIA)-associated uveitis or chronic anterior uveitis can safely take adalimumab (or biosimilar)…
- Trial name
- ADAPT (NCT07699107)
- Testing
- Adalimumab/Biosimilar
- Where
- 18 sites in United States, Italy and 1 more
- Volunteers
- 160 people
- Sponsor
- Nisha Acharya
Uveitis, Cystoid Macular Edema
The Comparison Between the Therapeutic Affect of Intravitreal Diclophenac and Triamcinolone in Persistent Uveitic Cystoids Macular Edema
Cystoids macular edema (CME) is one of the most common causes of low vision due to uveitis. The treatment for reducing the intra-ocular inflammation can decrease the macular edema.
- Trial name
- NCT00893854
- Testing
- Diclophenac, Triamcinolone
- Where
- Iran
- Sponsor
- Shahid Beheshti University of Medical Sciences
Uveitis
Correlation Between Aqueous Protein Level and Clinical Grading of Flare and Flaremetry.
The purpose of this study is to compare flaremetry readings with the protein content of the aqueous humor and the clinical grading of flare.
- Trial name
- NCT01905579
- Testing
- Paracentesis of the anterior chamber
- Where
- Saudi Arabia
- Volunteers
- 20 people
- Sponsor
- The Eye Center and The Eye Foundation for Research in Ophthalmology
Uveitis, JIA
Adalimumab in JIA-associated Uveitis Stopping Trial
The proposed study is a stratified, block-randomized, double-masked, controlled trial to determine the feasibility of discontinuing adalimumab treatment in patients with quiescent uveitis associated with juvenile idiopathic…
- Trial name
- ADJUST (NCT03816397)
- Testing
- Adalimumab
- Where
- 21 sites in United States, Australia and 1 more
- Volunteers
- 87 people
- Sponsor
- Nisha Acharya
Uveitis Affecting the Posterior Segment
Pilot Study of a Fluocinolone Acetonide Intravitreal Insert (FA-i) to Treat Intermediate-, Posterior-, or Panuveitis
The purpose of this study is to determine the tolerability, safety, and benefits of an investigational drug,Fluocinolone Acetonide Intravitreal Insert (FA-i), in people who have posterior uveitis.
- Trial name
- Iluvien (NCT01781936)
- Testing
- Fluocinolone Acetonide
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Glenn Jaffe
Macular Edema, Cystoid, Uveitis
Vascular Endothelial Growth Factor (VEGF) in Uveitis
This study will look for the presence in blood of a substance called vascular endothelial growth factor (VEGF) in patients with uveitis (eye inflammation).
- Trial name
- NCT00001738
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Uveitis
A Phase I/IIa Study for the Treatment of Uveitis With Iontophoresis
The multiple properties of the corticosteroids over the inflammatory response, make them first line drugs for the treatment of several ocular inflammatory disorders of different etiologies.
- Trial name
- NCT00499551
- Testing
- Iontophoresis second generation Eyegate II device
- Where
- Mexico
- Sponsor
- Asociación para Evitar la Ceguera en México
Uveitis, Scleritis
Human Samples and Data Repository
This protocol will enable IRB (institutional review board) review of proposed research using human samples and data collected under the terminated NIH studies 04-EI-0065 and 96-EI-0096.
- Trial name
- NCT00539370
- Where
- United States
- Volunteers
- 1,862 people
- Sponsor
- National Eye Institute (NEI)
Uveitis
Leflunomide to Treat Uveitis
This study will investigate the safety and effectiveness of the drug Leflunomide to treat uveitis-an inflammation of the eye caused by an immune system abnormality.
- Trial name
- NCT00001863
- Testing
- Leflunomide
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- National Eye Institute (NEI)
Uveitis
HUMIRA® Long-term Treatment in Patients With Non-infectious Intermediate-, Posterior-, or Pan-uveitis
This study evaluates the long- term safety and effectiveness of adalimumab in participants with non-infectious intermediate-, posterior-, or pan-uveitis in daily practice in Japan.
- Trial name
- NCT02916017
- Where
- 39 sites in Japan
- Volunteers
- 259 people
- Sponsor
- AbbVie
Uveitis, Posterior, Uveitis, Intermediate
A Study of LX211 in Active Sight Threatening, Non-infectious Intermediate-, Anterior and Intermediate-, Posterior-, or Pan-Uveitis
The objective of this study is to evaluate the safety and efficacy of LX211 as therapy in subjects with active non-infectious uveitis
- Conditions
- Uveitis, Posterior, Uveitis, Intermediate, Panuveitis
- Trial name
- LUMINATE (NCT00404612)
- Testing
- LX211
- Where
- 41 sites in United States, Austria and 5 more
- Volunteers
- 218 people
- Sponsor
- Lux Biosciences, Inc.