Clinical trials: Vaccination Pain
Quality of Life, Injection Site Reaction
Simultaneous mRNA COVID-19 and IIV4 Vaccination Study
This study is a prospective, randomized clinical trial. During this study, participants will be randomly assigned to receive quadrivalent inactivated influenza vaccine (IIV4) and mRNA COVID-19 vaccine either simultaneously or…
- Conditions
- Quality of Life, Injection Site Reaction, Adverse Drug Event, Systemic Reaction
- Trial name
- NCT05028361
- Testing
- mRNA COVID-19, IIV4
- Where
- 3 sites in United States
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- Duke University
Acute Pain
Improving Parental Soothing by Video
This study sets out to compare the effectiveness of a parent pain management coaching video that is 5-minutes in length. The investigators will be comparing an active-video to a placebo-video of equal length (and identical…
- Trial name
- NCT01826383
- Testing
- Active-Video
- Where
- 2 sites in Canada
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- York University
Immunisation Anxiety Related Reaction, Pain, Acute
Substance P as a Biomarker to Evaluate the Reduction of Multiple Immunization Pain
Immunization is one of the most significant preventive health measures in reducing morbidity and mortality caused by infectious diseases.
- Trial name
- NCT04103801
- Testing
- Sucrose
- Where
- Jordan
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Pain
Effectiveness of Distraction Techniques on Pain Intensity During Immunization Among Infants
A study to assess and compare the effectiveness of Distraction techniques on Pain intensity during Immunization among Infants in selected hospital of Ambala, Haryana.
- Trial name
- NCT03222050
- Testing
- Distraction technique
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Maharishi Markendeswar University (Deemed to be University)
Fear of Pain, Fear
Effect of Using Virtual Reality Goggles on Fear and Pain Level During Vaccination in Children
The study was designed as a randomized controlled experimental research with the purpose of determining the effect of distraction by using Virtual Reality Glasses reducing fear and pain during routine vaccination in children.
- Conditions
- Fear of Pain, Fear, Virtual Reality, Pain
- Trial name
- NCT06560320
- Testing
- Virtual Reality Glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Burdur Mehmet Akif Ersoy University
Pain Due to Childhood Vaccination
Distraction and Vibration for Minimizing Pain During Childhood Vaccination
Vaccine pain control is one of the actions suggested to support the delivery of vaccines that are on a vaccine schedule, since pain and anxiety associated with vaccines are among the main reasons why children and their parents…
- Trial name
- NCT03540589
- Testing
- Buzzy specific vibration device, Distraction
- Where
- Brazil
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Hospital Nossa Senhora da Conceicao
Pain
Effectiveness of Different Non-pharmacological Methods in Pain Management During Vaccination.
Aim: This study was conducted to determine and compare the effectiveness of different non-pharmacological methods in pain management during vaccination.
- Trial name
- NCT04436185
- Testing
- Comparisons of procedural pain
- Where
- Turkey (Türkiye)
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Inonu University
Immunization
Testing Educational Materials in a Paediatric Setting
Immunization procedures are a common source of iatrogenic pain for infants. A recently developed clinical practice guideline, led by Taddio et al., created evidence-based strategies for management of immunization pain.
- Trial name
- NCT01713322
- Testing
- Pain management education, No pain management education
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Vaccine Reaction
Infant Pain During Vaccination and Maternal Anxiety
This research was planned to determine the effect of two different methods on infant pain during vaccination and mother anxiety.The study was planned as a randomized controlled trial.
- Trial name
- NCT05598372
- Testing
- shotblocker, lullaby
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Pain
Effectiveness of Helfer Skin Tap Technique and ShotBlocker Technique
The purpose of this study is to examine the effectiveness of the Helfer Skin Tap Technique and the ShotBlocker Technique in reducing pain in babies receiving intramuscular vaccination.
- Trial name
- NCT06246266
- Testing
- Helfer Skin Tap Technique group, ShotBlocker Technique group
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Infant Pain Management
White Noise and Buzzy for Reducing Pain During Infant Vaccination
This randomized controlled trial aims to evaluate the effectiveness of two non-pharmacological methods-white noise and the Buzzy device-in reducing pain experienced by infants during routine vaccination.
- Trial name
- NCT07286721
- Testing
- Standard Care (in control arm)
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Istanbul Arel University
Pain, Pain, Acute
Effect of Cold Application and Vibration in Reducing Pain During Vaccination in Children
The study was designed as a randomized controlled experimental research with the purpose of determining the effect of using Cold Application and Vibration in reducing pain during routine vaccination in children.
- Conditions
- Pain, Pain, Acute, Vaccination, Children
- Trial name
- NCT06566378
- Testing
- Buzzy, Buzzy (Placed in standard)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Burdur Mehmet Akif Ersoy University
Pain, Breast Feeding
Non-Pharmacological Methods for Reducing Pain During Vaccination in Infants
Pain management in infants is a medical responsibility of all members of the healthcare team, and nurses hold a privileged role in this regard.
- Conditions
- Pain, Breast Feeding, Maternal Behavior
- Trial name
- NCT06886412
- Testing
- Maternal Holding Intervention Group, Breast Feeding Intervention Group
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Yalova
Pain
"The Effect of Snow Globe Used in Infancy Vaccination Applications on Pain Level."
The aim of this research is to determine the effect of the snow globe, which is used as a method of diverting attention, to the perception of pain that develops during the application of vaccines in infants between 2-6 months of…
- Trial name
- NCT04772430
- Testing
- snow globe
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Healthy Infants, Immunization
A Study of Two Injection Techniques to Reduce Pain in Infants Undergoing Immunization
Immunization injections are a significant source of pain for infants. Tactile stimulation (rubbing/applying pressure) may be an effective and feasible pain-relieving intervention - it is cost neutral, and has been shown to be…
- Conditions
- Healthy Infants, Immunization, Pain Management
- Trial name
- NCT01601197
- Testing
- Tactile stimulation
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Vaccination Reaction, Vaccination Pain
CARD for Community Pharmacy Vaccinations
To integrate CARD in community pharmacy-led vaccinations and document impact on vaccine clients and pharmacy staff.
- Conditions
- Vaccination Reaction, Vaccination Pain, Community Pharmacy
- Trial name
- NCT06098703
- Testing
- CARD (Comfort Ask Relax Distract)
- Where
- Canada
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Vaccination Pain Management
Rotavirus vs. Sucrose for Vaccine Injection Pain
This randomized trial will compare the analgesic effectiveness of oral rotavirus vaccine to sugar water for reducing vaccine injection pain in infants.
- Trial name
- NCT02174705
- Testing
- Sucrose, Rotavirus
- Where
- 2 sites in Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Anna Taddio
Procedural Pain, Pain, Acute
The Effect of Facilitated-tucking and ShotBlocker on Pain Caused by Vaccination in Healthy Infants
This study will be investigated the effects of facilitated tucking, ShotBlocker and combined facilitated tucking and ShotBlocker methods on procedural pain, crying time and duration of the procedure during Hepatitis B vaccine…
- Conditions
- Procedural Pain, Pain, Acute, Nursing Caries
- Trial name
- NCT06377748
- Testing
- Facilitated tucking position, ShotBlocker, Combined facilitated tucking and ShotBlocker
- Where
- Turkey (Türkiye)
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Procedural Pain
Non-immersive Virtual Reality for Pediatric Pain Management
This is a multicenter, randomized, clinical trial comparing treatment as usual to distraction with video projection or virtual reality in the management of pediatric (3-6 years) pain associated with venipuncture, intramuscular…
- Trial name
- NCT03985930
- Testing
- Distraction with virtual reality, Treatment as Usual
- Where
- Colombia
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Claudia Aristizábal
Virtual Reality, Vaccination
Virtual Reality for the Treatment of Pain in Pediatric Vaccination
Objective: to estimate the effect of virtual reality as a distracting technique against traditional distracting techniques in the vaccination procedure in the pediatric population. Design: randomized clinical trial.
- Conditions
- Virtual Reality, Vaccination, Pain, Nursing
- Trial name
- NCT04096833
- Testing
- Virtual Reality Group
- Where
- Spain
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Cardenal Herrera University