Clinical trials: Variability
Perfusion Index, Plethysmography
Evaluation of Caudal Block and Ilioinguinal-ilioohypogastric Nerve Block Efficacy with Perfusion Index (PI)
The study is a prospective, randomised, controlled double-blind clinical trial. The primary aim was to evaluate the efficacy of caudal block and ilioinguinal-iliohypogastric nerve block with PI and PVI in pediatric inguinal…
- Conditions
- Perfusion Index, Plethysmography, Anesthesia, Caudal, Nerve Block
- Trial name
- NCT06203743
- Testing
- caudal block group, ilioinguinal-iliohypogastric nerve block group
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Attention Deficit Disorder with Hyperactivity, Diabetes Mellitus, Type 1
Lisdexamphetamine Vs Methylphenidate for Pediatric Patients with ADHD and Type 1 Diabetes
This clinical trial aims to evaluate the safety and effectiveness of an intervention involving parental training in behaviour management and medication in children with both Type 1 Diabetes (T1D) and Attention Deficit Disorder…
- Trial name
- LAMAinDiab (NCT05957055)
- Testing
- parental training in behavior management, Lisdexamfetamine, Methylphenidate
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Medical University of Lodz
Diabetes
Relationship Between Blood Glucose Variability and Prognosis in Critically Ill Patients
This study is to evaluate the glycemic variation using Continuous Glucose Monitoring System in patients in the intensive care unit, find out the occult hypoglycemia, and investigate the relationship between glycemic variation…
- Trial name
- NCT03629704
- Testing
- Continuous Glucose Monitoring System
- Volunteers
- 200 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Pediatric Solid Organ Transplant
Continuous Hemoglobin Monitoring in Pediatric Transplant
The purpose of this study is to determine the clinical utility of non-invasive monitoring of Hemoglobin (Hgb) and Plethysmograph Variability Index (PVI) values during the intraoperative period of visceral solid organ…
- Trial name
- NCT00958984
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Nebraska
Epilepsy; Syndrome, Seizures of Localized Onset
Does Levetiracetam and Carbamazepine Impact the Autonomic Activity of Children With Self-limiting Focal Epilepsy?
The goal of this cross-sectional study is to learn about autonomic cardiac profile changes in children with self-limiting focal epilepsy using levetiracetam and carbamazepine in children with self-limiting focal epilepsy…
- Trial name
- levcbz (NCT06138847)
- Testing
- electroencephalogram
- Where
- Turkey (Türkiye)
- Volunteers
- 119 people
- Sponsor
- İpek Dokurel
Movement Disorders, Muscle Tone
Massage and Cold Water Immersion on Movement Variability After Fatigue in Swimmers
The goal of this clinical trial is to investigate the effectiveness of post-exercise massage and cold-water immersion compared to control in young elite swimmers.
- Conditions
- Movement Disorders, Muscle Tone, Perceived Exertion
- Trial name
- NCT04541901
- Testing
- Massage, Cold water immersion
- Where
- Brazil
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Flávia Carvalho
Traumatic Brain Injury
Prediction of Neurological Outcome of Children After a Traumatic Brain Injury Based on an Integrated Predictive Model
This study aims to develop a integrated predictive model based on serum biomarkers, HRV, and an innovative computerized classifier output, to predict the patient long term neurological outcome after a moderate or severe TBI in…
- Trial name
- NCT04157634
- Testing
- Prognostication model
- Volunteers
- 70 people
- Sponsor
- St. Justine's Hospital
Autism Spectrum Disorder
Play Therapy With Gamified Biofeedback in Children With Autism Spectrum Disorder
This clinical trial tests whether combining regular play therapy with gamified biofeedback helps children with autism spectrum disorder better regulate their emotions and improve social skills, compared to play therapy alone.
- Trial name
- NCT07322640
- Testing
- Gamified Biofeedback, Play Therapy, Deactivated Biofeedback
- Where
- Brazil
- Volunteers
- 68 people
- Sponsor
- Luiz Alexandre Viana Magno
Atrial Fibrillation
Studies of Disorders and Mechanisms Related to Atrial Fibrillation Before and After DC-Conversion.
The purpose of this study is to investigate if breathing disorders are related to atrial fibrillation and if it is possible to predict recurrence of atrial fibrillation after DC-conversion by changes in heart rate variability and…
- Trial name
- NCT00429884
- Where
- Sweden
- Sponsor
- Umeå University
Pulmonary Disease, Chronic Obstructive
Summer-Winter Variability in the Level of Physical Activity in Daily Life in Brazilian and Belgian Patients With COPD
Up to this moment, the majority of studies assessing the level of physical activity in daily life in patients with COPD are limited to a cross-sectional design, which does not take into account natural variation of physical…
- Trial name
- NCT01779960
- Testing
- Londrina, Leuven
- Where
- 2 sites in Belgium, Brazil
- Volunteers
- 40 people
- Sponsor
- Universidade Estadual de Londrina
Muscle Relaxation
Interindividual Variability in Duration of Action of Rocuronium in Pediatric Patients
Muscle relaxants represent an important part of general anesthesia in adult and pediatric patients. Their role is to facilitate intubation and enable some surgical interventions.
- Trial name
- DurAct (NCT05529420)
- Testing
- measurement of the depth of neuromuscular blockade
- Where
- Czechia
- Volunteers
- 107 people
- Sponsor
- Brno University Hospital
Cerebral Palsy (CP)
The Effect of Spinal Manipulation on Heart Rate Variability in Children With Cerebral Palsy.
This randomized, sham-controlled crossover trial aims to evaluate the immediate effects of spinal manipulation on heart rate variability in children with cerebral palsy.
- Trial name
- NCT07504640
- Testing
- Spinal manipulation
- Where
- Ukraine
- Volunteers
- 20 people
- Sponsor
- International Clinic of Rehabilitation, Ukraine
Behçet's Syndrome (BS)
Prospective Multiethnic Validation of the Behçet's Syndrome Overall Damage Index (BODI)
PROBE is an observational multicenter cohort study, consisting of a cross-sectional and a 5-years prospective phase, designed to target the major study objectives, such as testing the comprehensiveness of the Behçet's syndrome…
- Trial name
- PROBE (NCT07073261)
- Where
- Italy
- Volunteers
- 970 people
- Sponsor
- University of Cagliari
Scoliosis, Radiation Exposure
Inter-variability in Radiographic Fluoroscopic Technique in Patients With Idiopathic Scoliosis
Radiographical images in Adolescent idiopathic scoliosis (AIS) can have a potential radiation-induced oncogenic effect. In this study, the investigators aim to compare a fluoroscopic imaging technique (LFT) with traditional…
- Conditions
- Scoliosis, Radiation Exposure, Evaluable
- Trial name
- IVIS (NCT05673473)
- Testing
- scoliosis radiographs
- Volunteers
- 342 people
- Sponsor
- christian wong
Congenital Bleeding Disorder, Haemophilia A
Intra-subject Variability Following Administrations of Activated Recombinant Human Factor VII in Haemophilia Patients in a Non-bleeding State
This trial is conducted in Asia and Europe. The aim of this trial is to evaluate the intra-subject variability of thromboelastographic parameters (TEG® and ROTEM®) following two administrations of activated recombinant human…
- Conditions
- Congenital Bleeding Disorder, Haemophilia A, Haemophilia B
- Trial name
- NCT01562457
- Testing
- activated recombinant human factor VII
- Where
- 3 sites in France, Germany and 1 more
- Volunteers
- 30 people
- Sponsor
- Novo Nordisk A/S
Post-immunisation Apnoea and Bradycardia of Prematurity (AOP)
Predictive Value of Heart Rate Variability on Cardiorespiratory Events
The aim of this study are to investigate whether heart rate variability (HRV) parameters derived from nonlinear time series analysis at five different time points have prognostic utility for assessing the risk of postimmunisation…
- Trial name
- NCT04303494
- Testing
- immunisation
- Where
- Switzerland
- Volunteers
- 292 people
- Sponsor
- University Hospital, Basel, Switzerland
Type 1 Diabetes
Washed Microbiota Transplantation for Type 1 Diabetes Mellitus
This is a real-world study to explore the safety and the efficacy of washed microbiota transplantation (WMT) for patients with Type 1 Diabetes Mellitus (T1DM).
- Trial name
- NCT06256614
- Testing
- WMT
- Where
- China
- Volunteers
- 50 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Efficacy, Self, Fatigue; Muscle, Heart
Neuromodulation of the Autonomic Nervous System in Athletes
There are few studies in the literature that have evaluated the effects of using percutaneous stimulation of the auricular branch of the vagus nerve for sports purposes (to accelerate recovery after physical exertion).
- Conditions
- Efficacy, Self, Fatigue; Muscle, Heart, Fatigue, Mental, Fatigue; Combat
- Trial name
- NANSA (NCT06281795)
- Testing
- tVNS
- Where
- Russia
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Bakulev Scientific Center of Cardiovascular Surgery
Multiple Chronic Illnesses
Assessing Costs & Cost-variability Among Enrollees of Health Insurance Programs Utilizing Charlson's Comorbidity Index and Administrative Databases
This study will involve the evaluation of the cost profile of about approximately 241,000 patients (15,000 who are members of the Generations Plus/ Northern Manhattan Health Network AND 226,000 members of a large self insured…
- Trial name
- NCT01761253
- Where
- United States
- Volunteers
- 241,000 people
- Sponsor
- Weill Medical College of Cornell University
Duchenne Muscular Dystrophy
Wearable Technology to Evaluate Hyperglycemia and HRV in DMD
Duchenne muscular dystrophy (DMD) is an X-linked disorder that causes muscle wasting, cardiopulmonary failure, and premature death.
- Trial name
- NCT06124196
- Testing
- wearable technology
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center