Clinical trials: Variability
Vascular Ehlers-Danlos Syndrome
Heart Coherence Training on Vascular Ehlers-Danlos Syndrome Patients
Vascular Ehlers-Danlos Syndrome (VEDS) is caused by pathogenic variants of the COL3A1 gene, resulting abnormal Type III collagen protein.
- Trial name
- NCT05994664
- Testing
- Heartmath Intervention, Control Group
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Baylor College of Medicine
Duchenne Muscular Dystrophy
Wearable Technology to Evaluate Hyperglycemia and HRV in DMD - Longitudinal Aim
Duchenne Muscular Dystrophy (DMD) is an X-linked disorder that causes muscle wasting, cardiopulmonary failure, and premature death.
- Trial name
- NCT06093100
- Testing
- wearable technology
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Vanderbilt University Medical Center
Bipolar Disorder, Subsyndromal Depressive Phase
Heart Rate Variability of Patients With Bipolar Disorder in Subsyndromal Depressive Phase
The purposes of this study were: (1) to compare heart rate variability between bipolar patients in subsyndromal depressive phase and healthy controls (2) to evaluate the relation between the severity of subsyndromal depressive…
- Conditions
- Bipolar Disorder, Subsyndromal Depressive Phase, Heart Rate Variability
- Trial name
- NCT01455038
- Where
- South Korea
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Recurrent Abdominal Pain
The Treatment of Recurrent Abdominal Pain in Children
The purpose of this study is to determine if two treatments, a biofeedback and behavioral protocol, for recurrent abdominal pain are equally effective.
- Trial name
- NCT00852878
- Testing
- Biofeedback, Behavioral Protocol
- Where
- United States
- Sponsor
- Kaiser Permanente
Pain, Spinal Surgeries, Hip and Knee Joint Replacement, Adverse Events
RAHM Foundation Retrospective Study of Various Diseases
This is a retrospective data collection on treatment of various disorders. This registry will include a variety of different products, implants, technologies and procedures.
- Trial name
- NCT02359786
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Rahm Foundation
Anesthesia, Fluid Responsiveness
RPVI for Fluid Responsiveness in Children
The purpose of this study is to validate Rainbow pleth variability index for prediction of fluid responsiveness in children.
- Trial name
- NCT05601622
- Testing
- Fluid loading, Transthoracic echocardiography, PVI, RPVI
- Volunteers
- 45 people
- Sponsor
- Seoul National University Hospital
Prediction of Extubation Readiness
Prediction of Extubation Readiness in Extreme Preterm Infants by the Automated Analysis of CardioRespiratory Behavior
The investigators hypothesize that machine learning methods using a combination of novel, quantitative measures of cardio-respiratory variability can accurately predict the optimal time to extubate extreme preterm infants.
- Trial name
- NCT01909947
- Testing
- Cardiorespiratory signal acquisition
- Where
- 5 sites in United States, Canada
- Volunteers
- 266 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
T1DM, Sleep Disorders, Circadian Rhythm
Influence of Circadian Clock on Hormonal, Metabolic, Neurocognitive Markers in Adolescents With and Without Diabetes
Type 1 diabetes mellitus (T1DM), makes its appearance during childhood and youth, but management implications last till late adulthood.
- Conditions
- T1DM, Sleep Disorders, Circadian Rhythm, ADHD, Memory Impairment
- Trial name
- NCT04054934
- Testing
- Reversed Circadian Rhythm, Normal Circadian Rhythm
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Cystic Fibrosis
A Study to Determine the Variability of a 6-Minute Walk Test in Cystic Fibrosis Subjects With Advanced Lung Disease
This is an observational study to be conducted at approximately 25 sites in the United States. Approximately 25 subjects with severe obstructive CF lung disease (FVC <40% predicted) will be enrolled.
- Trial name
- NCT00311506
- Volunteers
- 25 people
- Sponsor
- Genentech, Inc.
Healthy
Cranberry Flavan-3-ols Consumption and Gut Microbiota in Healthy Adults
Consumption of (poly)phenols is recognized to have beneficial effects on health. However, heterogeneous results are obtained in clinical trials due to high inter-individual variability.
- Trial name
- NCT05931237
- Testing
- Cranberry extract capsules
- Where
- Canada
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Laval University
Traumatic Brain Injury, Child Development
Heart Rate Variability in Children With Traumatic Brain Injury
Using a prospective cohort of children admitted to the PICU, the investigators will determine HRV monitoring is feasible, if a decreased HRV in the 7 days following moderate or severe TBI in children is associated with a worse…
- Trial name
- HRV-TBI (NCT03701620)
- Testing
- HRV monitoring
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- St. Justine's Hospital
Sickle Cell Disease
HRV-B for Symptom Management in Sickle Cell Patients
This study will test the hypothesis that Heart Rate Variability Biofeedback (HRV-B) restores autonomic balance and reduces pain and other symptoms among patients with sickle cell disease (SCD).The specific aims of this study are…
- Trial name
- NCT03383913
- Testing
- Heart Rate Variability Biofeedback
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Prisma Health-Upstate
Attention Deficit Hyperactivity Disorder
Response Variability in Children With Attention Deficit Hyperactivity Disorder (ADHD)
Children with Attention Deficit Hyperactivity Disorder (ADHD) have numerous areas of neuropsychological dysfunction including response inhibition, working memory, and attention.
- Trial name
- NCT01238822
- Testing
- Methylphenidate
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Heart Rate, Variability
Heart Rate Variability in Febrile Young Infants
Febrile infants younger than 3 months old present a diagnostic dilemma to the emergency physician. Tension remains between the need for early aggressive intervention among patients with suspected sepsis and the global phenomena…
- Conditions
- Heart Rate, Variability, Triage, Decision Support Techniques
- Trial name
- HRV (NCT04103151)
- Testing
- Single lead ECG
- Where
- Singapore
- Volunteers
- 330 people
- Sponsor
- KK Women's and Children's Hospital
Congestive Heart Failure
Effect of Bi-ventricular Pacing on Autonomous Nervous System
Patients with congestive heart failure are often associated with delayed intraventricular depolarization which causing dyssynchrony and an inefficient pattern of left ventricular contraction.
- Trial name
- NCT00190138
- Testing
- Bi-ventricular pacing
- Sponsor
- Far Eastern Memorial Hospital
Type 1 Diabetes
The VIGORous Physical Activity for Glycaemic Control in Type 1 Diabetes (VIGOR) Trial
Background/Justification: Regular physical activity (PA) has substantial health benefits in persons with type 1 diabetes (T1D), including reduced risk of complications and cardiovascular mortality.
- Trial name
- VIGOR (NCT01834144)
- Testing
- Exercise Training
- Where
- 5 sites in Canada
- Volunteers
- 4 people
- Sponsor
- University of Manitoba
Autistic Disorders Spectrum
Heart Rate Variability Biofeedback in Young People With Autism
Biofeedback is a process that allows people to obtain information about their internal physiological reactions and thereby learn to control them.
- Trial name
- NCT04955093
- Testing
- Biofeedback
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Ulster
Hypertension, Left Ventricular Hypertrophy
Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE)
Studying the causal roles of components of the renin-angiotensin-aldosterone system (including angiotensin-(1-7) (Ang-(1-7)), angiotensin-converting enzyme 2 (ACE2), Ang II, and ACE), uric acid, and klotho in pediatric…
- Conditions
- Hypertension, Left Ventricular Hypertrophy, Left Ventricular Dysfunction, Left Atrial Dilatation
- Trial name
- PHRASE (NCT04752293)
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Stress
Coherence Training for Military Personnel
Military operations and training situations present many physical and psychological challenges for service members to adapt to and overcome.
- Trial name
- NCT01599598
- Testing
- Progressive Muscle Relaxation, Coherence Advantage
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- United States Naval Medical Center, San Diego
Healthy
A Replicate Crossover Trial on Nutritional Supplementation in Association Football (Soccer)
Problems of sleep disorders and disruption are common particularly in Arab populations, and sleep insufficiency hinders the pursuit of high performance and optimal recovery following training and competition.
- Trial name
- AANOF1 (NCT07190989)
- Testing
- Nutritional Supplement
- Where
- Qatar
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Aspire Academy