Clinical trials: Variability
Brain Concussion, Mild Traumatic Brain Injury
A Study on the Effect of Mindfulness-based Yoga on Youth With Persistent Concussion Symptoms
Mild traumatic brain injury (mTBI), also known as concussion, is of great concern in the youth population, with incidences of injury steadily increasing within the past few years.
- Trial name
- NCT03217695
- Testing
- Mindfulness-based Yoga Arm
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Fetal Growth Retardation
Fetal Heart Rate Variability
Need statement a new way to distinguish between a healthy small fetus and a small fetus suffering from deprivation of nutrition and oxygen to prevent unnecessary induction of preterm birth and improve neonatal outcome.
- Trial name
- NCT04323865
- Testing
- fetal heart rate variability
- Where
- Denmark
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Cerebral Palsy, Autonomic Nerveus System
BioFeedBack Breathing Training Influence Cardiac Autonomic Nervous System in Children With Cerebral-Palsy.
The effect of breathing biofeedback training to influence the function of the cardiac autonomic nervous system at rest and in activity in children with cerebral palsy.
- Trial name
- NCT01872507
- Testing
- Biofeedback training
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Hadassah Medical Organization
Acute Respiratory Distress Syndrome, Acute Lung Injury
Genetic Variability and Biomarkers in Children With Acute Lung Injury
Acute Lung Injury (ALI) and the more severe Acute Respiratory Distress Syndrome (ARDS) are a significant problem in Pediatric Intensive Care Units, affecting up to 16 of every 1000 children admitted to these units.
- Trial name
- BALI (NCT01048996)
- Where
- United States
- Sponsor
- Medical College of Wisconsin
Neoplasms
Interindividual Genetic Variability as a Determinant of Chemotherapy Toxicity and Response in Pediatric Bone Marrow Transplantation Patients
The purpose of this study is to develop tests that will allow us to determine who will react differently to the drugs used to treat cancer.
- Trial name
- NCT00578630
- Testing
- buccal swabs and obtaining peripheral blood
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
COVID-19
Role of HLA Genes and Innate Immunity in the Phenotypic Variability of COVID-19
Case-control, prospective retrospective association study of patients infected with SARS-CoV2 and cured by COVID19. Recruited patients were divided into two cohorts (cases: patients with respiratory failure that required…
- Trial name
- 3490 (NCT05711836)
- Testing
- HLA-genotyping
- Where
- Italy
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Sudden Cardiac Death
Predictive Risk Stratification Through T Variability in ICD Patients Without Pacing Indications
The aim of the study is to assess the negative predictive value of the T amplitude variance as a method for risk stratification for patients with an increased risk for SCD.
- Trial name
- Prediction (NCT00560768)
- Testing
- Ovatio VR 6250 or DR6550
- Where
- 30 sites in United States, Canada and 2 more
- Volunteers
- 198 people
- Sponsor
- LivaNova
Duchenne Muscular Dystrophy
Heart Rate Variability in Duchenne Muscular Dystrophy During Computer Task
HRV is attained using a Polar RS800CX. Then, evaluated through linear, non-linear and chaotic global techniques (CGT). Forty-five male subjects were included in the DMD group and age-matched with forty-five in the healthy Typical…
- Trial name
- NCT04607824
- Testing
- Duchenne Muscular Dystrophy group, Typical Development group
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Diabetes, Diabetes Mellitus, Type 1
Observational Study to Evaluate the Safety of Levemir® in Patients With Diabetes
This study is conducted in Europe. The aim of the study is to observe the safety of insulin detemir (Levemir®) in patients with type 1 and type 2 diabetes patients.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- PREDICTIVE™ (NCT01545791)
- Testing
- insulin detemir
- Where
- 2 sites in Ireland, United Kingdom
- Volunteers
- 1,037 people
- Sponsor
- Novo Nordisk A/S
Suppurative Otitis Media
The Microbiome Variability and Antibiotic Resistance of Chronic Suppurative Otitis
ear swabs will be collected from 120 patients with established CSOM at the ear-nose-throat (ENT) outpatient clinic at the Ziv medical center, and 120 swabs will be taken from children with Otitis Media with Effusion (OME)…
- Trial name
- NCT03456739
- Volunteers
- 240 people
- Sponsor
- Ziv Hospital
Vitamin D3 Deficiency, Prematurity
Vitamin D and Health Outcomes in Preterm Born Population
Improved survival of very preterm newborn population during the last decades has challenged us neonatologists to study and improve nutritional practices including vitamin D (VitD) supplementation.
- Conditions
- Vitamin D3 Deficiency, Prematurity, Lung Diseases, Heart Rate Variability
- Trial name
- ViDePrePop (NCT04342078)
- Testing
- Vitamin D
- Where
- Finland
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Oulu
Glucose Variability
Glucose Variability
A retrospective data review of 243 pregnant women (≤32 wks gestational age), dtat collected prior to 5/18/2014, with GDM, or T2DM, and their infants (until discharge from the hospital, typically up to 1 week after deliver) will…
- Trial name
- NCT03028259
- Testing
- lab results
- Volunteers
- 161 people
- Sponsor
- St. Louis University
Parasympathetic Cardiovascular Function Disorder
Heart Rate Variability and Cardiorespiratory Complications During Ophthalmic Arterial Chemotherapy for Retinoblastoma
A patient undergoing ophthalmic arterial chemosurgery may experience a sudden, profound decrease in lung compliance when the microcatheter is in the ICA or ophthalmic artery.
- Trial name
- NCT03450590
- Where
- South Korea
- Volunteers
- 38 people
- Sponsor
- Seoul National University Hospital
Brain Injuries, Craniocerebral Trauma
DASH After TBI Study: Decreasing Adrenergic or Sympathetic Hyperactivity After Traumatic Brain Injury
The investigators intend to determine the effect of adrenergic blockade on 1) short-term physiology, behavior, and cognition and 2) long-term neuropsychological outcomes after severe Traumatic Brain Injury (TBI).
- Conditions
- Brain Injuries, Craniocerebral Trauma, Trauma, Nervous System, Traumatic Brain Injury
- Trial name
- NCT01322048
- Testing
- IV Propranolol and Per Tube Clonidine
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Vanderbilt University
Primary Dysmenorrhea (PD)
Effects of Transcutaneous Tibial and Auricular Vagus Nerve Stimulation in Females With Primary Dysmenorrhea
Primary dysmenorrhea is a common gynecological condition characterized by painful menstrual cramps that can negatively affect daily activities and quality of life.
- Trial name
- NCT07834658
- Testing
- Transcutaneous Tibial Nerve Stimulation (TTNS), Transcutaneous Auricular Vagus Nerve Stimulation (TaVNS), TTNS+TaVNS
- Volunteers
- 66 people
- Sponsor
- Riphah International University
Burnout, Burnout Syndrome
Continuous Heart Rate Variability Monitoring in Doctors; Understanding Patterns of Stress and Recovery and Their Relationship With Self-reported Resilience, Burnout and Wellbeing.
Burnout is an increasing concern in the medical professions. This study aims to utilise established, validated self-report measures combined with continuous heart rate variability measurements to better understand the stress and…
- Conditions
- Burnout, Burnout Syndrome, Occupational Stress, Stress
- Trial name
- HEART-ED (NCT06721312)
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Autonomic Nervous System
The Influences of Caffeine on Heart Rate Variability of Preterm Infants
Caffeine has a stimulatory effect on the ANS. This has not yet been investigated in preterm infant who get caffeine before stopping ventilation.
- Trial name
- NCT01769118
- Testing
- Caffeine
- Where
- Israel
- Volunteers
- 25 people
- Sponsor
- Rambam Health Care Campus
Brain Injury, Cerebral Palsy
Heart Rate Variability (HRV) Among Children With Brain Damage
to investigate the function of the autonomic nervous system in children with with post traumatic brain injury and children with cerebral palsy through an analysis of heart rate variability (HRV) occurring with walking performance.
- Trial name
- NCT00746291
- Testing
- 6 min walk test, Step climbing
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Alyn Pediatric & Adolescent Rehabilitation Hospital