Clinical trials: Variability
Ventricular Tachyarrhythmia
Change in Heart Rate Variability Prior to Tachyarrhythmia in ICD Implanted Patients
To investigate changes in HRV during the time before a spontaneous episode of ventricular tachyarrhythmia.
- Trial name
- HRV (NCT00701467)
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Sheba Medical Center
Type1diabetes, Sleep
Sleep Patterns and Chronotype in Children With and Without Type 1 Diabetes
Type 1 diabetes (T1D) is one of the most common chronic childhood diseases. Recent studies have highlighted the strong association between type 1 diabetes and sleep health problems.
- Conditions
- Type1diabetes, Sleep, Chronotype
- Trial name
- NCT06318611
- Testing
- sleep, chronotype
- Where
- Turkey (Türkiye)
- Volunteers
- 168 people
- Sponsor
- Koç University
Intensive Care Units, Neonatal, Infant, Newborn
Heterogeneity Index in Neonatologist-performed Lung Ultrasound in Neonates Receiving Respiratory Support - a Pilot Study
Lung ultrasound is an increasingly valuable diagnostic tool in neonatal intensive care due to its safety and accessability. This pilot study investigates whether a quantitative approach - the heterogeneity index, previously only…
- Conditions
- Intensive Care Units, Neonatal, Infant, Newborn, Infant, Premature, Point-of-Care Systems
- Trial name
- NPLUS HI (NCT07117513)
- Where
- 2 sites in Austria
- Volunteers
- 40 people
- Sponsor
- Medical University of Graz
Mental Health Wellness 1, Positive and Negative Affect
Effects of a Relaxation and Guided Imagery Intervention in School Context
Specific aims - To test the effects of a relaxation and guided imagery intervention with socioemotional learning content on a range of socioemotional, physiological, cognitive and academic outcomes of school-aged children…
- Conditions
- Mental Health Wellness 1, Positive and Negative Affect, Social Skills, Happiness
- Trial name
- MR (NCT06101225)
- Testing
- MindRegulation Intervention, Relaxation, Waiting List Control Group
- Where
- Portugal
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Universidade Autónoma de Lisboa
Postoperative Confusion, Postoperative Delirium
Autonomous Nervous System Regulated Paediatric Anaesthesia With Dexmedetomidine or Placebo
The goal of this randomized, double blinded study is to examine in children whether postoperative agitation can be reduced. The main question it aims to answer is Will optimized, monitor guided analgesic treatment and…
- Conditions
- Postoperative Confusion, Postoperative Delirium, Postoperative Pain, Acute, Postoperative Complications
- Trial name
- ANNA (NCT05785689)
- Testing
- Dexmedetomidine
- Where
- Denmark
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Tonsillectomy, Adenoidectomy
Pharmacogenomics Analysis of Morphine Pharmacokinetics in Pediatric Tonsillectomy and Adenoidectomy
Intravenous (IV) morphine requirement for immediate postoperative pain control depends upon the complex interplay of patient history, wound severity, environment, and genetics.
- Conditions
- Tonsillectomy, Adenoidectomy, Pharmacokinetics
- Trial name
- NCT00836264
- Where
- United States
- Volunteers
- 878 people
- Sponsor
- Children's Hospital of Philadelphia
Heart Rate Variability (ANS Function)
Autonomic Nervous System and Sickle Cell Disease
Sickle cell disease (SCD) children and adults with asthma have an increased rate of vaso-occlusive crisis, acute chest syndrome episodes, and premature mortality when compared to those without asthma.
- Trial name
- DrepaSympa (NCT04062409)
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Abdominal Pain
Heart Rate Variability in Children With a Functional Gastrointestinal Disorder
The current study is designed to assess relationships between anxiety/stress, autonomic nervous system balance, and electrical activity in the stomach before and after eating/drinking in children with abdominal pain.
- Trial name
- NCT00195975
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Scoliosis
Accuracy of Pleth Variability Index (PVI) in Children
Plethysmographic Variability index is a simple index accurate in predicting fluid responsiveness. The aim of this study was to investigate its accuracy in predicting fluid response to intravenous fluid challenge during scoliosis…
- Trial name
- PVI (NCT01820845)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Spastic Cerebral Palsy
The Effect of AFOs on the EMG of Children With CP
Children with cerebral palsy (CP) have altered gait patterns as a result of primary and secondary symptoms. Ankle-foot orthoses (AFOs) are frequently used to improve their gait.
- Trial name
- NCT06532981
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Spastic Cerebral Palsy
Efficacy of Physical Fitness Training Combined With Exercise Therapy on Gait in Children With Cerebral Palsy
This observational study is designed to investigate the time-dynamic characteristics of gait variability in children with spastic cerebral palsy (SCP).
- Trial name
- NCT07316985
- Testing
- 3-Minute Walking Gait and Surface Electromyography Assessment
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- LiNa Zhang
Diabetes Mellitus, Type 1, Hypoglycemia
International Navigator Hypoglycaemia Study
The purpose of this study is to determine if the incidence and duration of hypoglycaemia (low blood sugar) is reduced through the use of the FreeStyle Navigator Continuous Glucose Monitoring System in people with Type 1 diabetes…
- Trial name
- NCT00843609
- Testing
- Navigator continuous glucose monitor (Freestyle Navigator®)
- Where
- 3 sites in Israel, Slovenia and 1 more
- Volunteers
- 122 people
- Sponsor
- University Medical Centre Ljubljana
Enterobacteriaceae Infections
The Burden and Genetic Variability of Extended-Spectrum ß-Lactamase (ESBL) - Producing Pathogens in Swiss Children
Objectives: The aim of the study is to determine the molecular epidemiology and genetic variability of ESBL-producing enterobacteriaceae (E-ESBL) among children in Switzerland and to estimate the associated clinical burden of…
- Trial name
- NCT00894036
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University Hospital, Geneva
Heart Rate Variability, Autonomic Nervous System
Analysis of Heart Rate Variability During Emergency Flight Simulator Missions in Fighter Pilots
The autonomous response of fighter and attack pilots who attend sessions in a flight simulator will be evaluated by measuring and analyzing heart rate variability (HRV).
- Trial name
- NCT04487899
- Testing
- Analysis of heart rate variability
- Where
- Spain
- Volunteers
- 18 people
- Sponsor
- Universidad de Extremadura
Fluid Responsiveness
Study About Predicting Fluid Responsiveness in Children Undergoing Neurosurgery
The purpose of this study is to evaluate static and dynamic parameters, echocardiographic parameters, and pleth variability index for predicting fluid responsiveness in children.
- Trial name
- NCT01364103
- Testing
- volume expansion
- Where
- 2 sites in South Korea
- Volunteers
- 33 people
- Sponsor
- Seoul National University Hospital
Anterior Cruciate Ligament Reconstruction, Anterior Cruciate Ligament Reconstruction Rehabilitation
Fractal vs Isochronous Cueing in Athletes After ACL Reconstruction
Anterior cruciate ligament (ACL) injuries are among the most prevalent and functionally limiting knee injuries in sports, particularly those that involve pivoting movements.
- Conditions
- Anterior Cruciate Ligament Reconstruction, Anterior Cruciate Ligament Reconstruction Rehabilitation, Athlete
- Trial name
- SyncGait (NCT07243535)
- Testing
- Fractal Cueing, Isochronous Cueing
- Where
- Portugal
- Volunteers
- 36 people
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Stress, Heart Rate Variability
Heart Rate Variability and Stress Management Enhancement
This study will be conducted by using two devices (Apollo and Biostrap) for monitoring of baseline physiologic variables and heart rate variability.
- Trial name
- NCT04381182
- Testing
- Apollo Wearable Device
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Joseph Maroon
Healthy, Wheezing, Non Wheezing Acute Respiratory Episode
Measurement of Expiratory Flow Variability for the Detection of Bronchospasm in Infants Using the Ventica® Device by Revenio
Wheezing in infants and children less than 3 years of age children is a frequent feature that might be difficult to diagnose when only the caregivers reporting is available.
- Trial name
- VENTICA (NCT04702620)
- Testing
- Ventica® device from Revenio
- Where
- France
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sleep
Feasibility of a Bedtime Variability Protocol
The purpose of this study is to find out if parents and children 6-10 years old are willing and able to follow a protocol to be used to study the effects of short and/or variable sleep in children.
- Trial name
- NCT06501690
- Testing
- Late bedtime, Variable bedtime
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Penn State University
Laparoscopic Surgery Simulation, Mental Workload
Impact of Preferred Music on Laparoscopic Task Performance and Mental Workload in Novice Surgeons
This single-blinded, three-arm randomized controlled trial evaluated the effects of different auditory environments on laparoscopic task performance and mental workload among novice surgeons in a simulated setting.
- Conditions
- Laparoscopic Surgery Simulation, Mental Workload, Stress, Psychomotor Performance
- Trial name
- NCT07738848
- Testing
- Behavioral: Preferred Music, White Noise, SIlent Control
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital Universiti Sains Malaysia