Clinical trials: Vasospasm
Subarachnoid Hemorrhage, Aneurysmal, Subarachnoid Hemorrhage
Remote Ischemic Preconditioning in Subarachnoid Hemorrhage
Rupture of brain aneurysms is a common cause of death and disability, accounting for as many as 10% of stroke cases in the United States.
- Conditions
- Subarachnoid Hemorrhage, Aneurysmal, Subarachnoid Hemorrhage, Cerebral Vasospasm, Intracranial Aneurysm
- Trial name
- RIPC-SAH (NCT01158508)
- Testing
- Remote ischemic preconditioning
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Los Angeles
Head Injury
Transcranial Doppler Measurement and Prognosis in Moderate Head Injury
The purpose of this study is to determine whether Transcranial Doppler measurements have correlation with neuropsychological test (Galvestone Orientation Amnesia Test), TC image (Marshall Scale) and prognosis (DRS and GOS) in…
- Trial name
- NCT00353444
- Where
- Mexico
- Volunteers
- 70 people
- Sponsor
- Universidad Autonoma de San Luis Potosí
Aneurysm
Delayed Vasospasm After Aneurysm With the Standardization Treatment of Traditional Chinese Medicine
Delayed vasospasm (DCVS) is the most serious complication of aneurysmal subarachnoid hemorrhage (aSAH) perioperative period ,the incidence rate up to 30% to 90%, and often can cause severe brain ischemia or brain damage of…
- Trial name
- NCT01840761
- Testing
- herbal drug
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Guangzhou University of Traditional Chinese Medicine
Traumatic Brain Injury
Physiologic Mechanisms in Pediatric Traumatic Brain Injury (TBI)
The aims of this study explore the relationships between cerebral vasospasm, apolipoprotein-E (apo-E) genotype, physiologic symptoms, and neurocognitive outcomes that may either intensify or ameliorate secondary injury, for…
- Trial name
- NCT01763892
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Duke University
Aneurysm, Vasospasm
Balloon Prophylaxis of Aneurysmal Vasospasm
The purpose of this study is to determine if early transluminal ballooning of the major cerebral arteries prevents severe vasospasm and improves neurological outcome in patients with Fisher Grade III aneurysmal subarachnoid…
- Trial name
- NCT00282893
- Testing
- transluminal ballooning, currently existing therapies for the treatment of vasospasm
- Where
- 5 sites in United States, Canada and 1 more
- Volunteers
- 170 people
- Sponsor
- University of California, Davis
Subarachnoid Hemorrhage, Pneumonia, Bacterial
Influence of Pneumonia on Delayed Cerebral Ischemia After Subarachnoid Hemorrhage . SAH-CIP (SubArrachnoid Hemorrhage - Cerebral Infarction Pneumonia)
Prognosis of subarachnoid hemorrhage (SAH) is scarce, indeed almost half patients die or become severely disable after SAH. Outcome is related to the severity of the initial bleeding and delayed cerebral infarction (DCI).
- Trial name
- SAH-CIP (NCT05094349)
- Where
- France
- Volunteers
- 224 people
- Sponsor
- University Hospital, Brest
Subarachnoid Hemorrhage, Brain Ischemia
Dapsone Use in Patients With Aneurysmal Subarachnoid Hemorrhage.
Dapsone is a drug that has been used clinically for several decades due to its anti-infective effect, making it widely available. Its neuroprotective effects have been found through its glutamate receptors antagonistic effect.
- Conditions
- Subarachnoid Hemorrhage, Brain Ischemia, Subarachnoid Hemorrhage, Aneurysmal, Aneurysmal Subarachnoid Hemorrhage
- Trial name
- NCT05131295
- Testing
- Dapsone, Aluminum Hydroxide Gel
- Where
- Mexico
- Volunteers
- 49 people
- Sponsor
- El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez
Coronary Disease, Intracranial Embolism
A Registry Study of Shuxuening Injection Used in Hospitals in China
The purpose of this study is get to know what and how Shuxuening injection in hospital results in adverse events or adverse drug reactions from a cohort event monitoring.
- Conditions
- Coronary Disease, Intracranial Embolism, Stroke, Angina Pectoris
- Trial name
- RSCMI-VII (NCT01752946)
- Volunteers
- 30,000 people
- Sponsor
- China Academy of Chinese Medical Sciences
Cerebral Vasospasm
Stellate Ganglion Block Using Ultrasound Guidance For Treatment Of Post Clipping Cerebral Vasospasm
The present study has been designed to assess the efficacy and safety of Stellate Ganglion Block (SGB) in relieving symptomatic cerebral vasospasm following aneurysmal clipping.
- Trial name
- NCT02775318
- Testing
- Stellate Ganglion Block, Bupivacaine, Transcranial Doppler
- Volunteers
- 20 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
SAH
Atorvastatin After Aneurysmal Subarachnoid Hemorrhage
The 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, known as statins, have recently been demonstrated to improve endothelial function.
- Trial name
- NCT01569100
- Volunteers
- 278 people
- Sponsor
- Groupe Hospitalier Pitie-Salpetriere
Coronary Artery Spasm, Hypertension
The Prevalence of Coronary Spasm in Hypertensive Patients Treated With Antihypertensive Medication
Autonomic nerve function is involved in both blood pressure (BP) regulation and the pathogenesis of coronary artery spasm(CAS), but few studies have been published about the relationship between CAS and effect of BP lowering…
- Trial name
- NCT01882790
- Where
- 3 sites in South Korea
- Volunteers
- 1,933 people
- Sponsor
- Korea University
Tbi, Vasospasm
Cerebral Autoregulation and Vasospasm in Patients With TBI
Traumatic brain injury (TBI) affects 1.5 million patients per year in the United States, resulting in more than 50,000 deaths and more than 230,000 hospitalizations annually.
- Conditions
- Tbi, Vasospasm, Cerebral Ischemia, Cerebral Infarct
- Trial name
- NCT02351518
- Testing
- No intervention
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Pediatrics, Anesthesia
Papaverine vs Heparin for Peripheral Arterial Catheter Patency in Pediatric Patients
The purpose of this study is to compare intraoperative papaverine plus heparin to heparin alone for prevention of arterial spasm and maintenance of patency of peripheral arterial catheters during surgery in pediatric patients.
- Conditions
- Pediatrics, Anesthesia, Vasospasm
- Trial name
- NCT03894904
- Testing
- Papaverine, Heparin, Rescue papaverine, as needed
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The University of Texas Health Science Center, Houston
Coronary Artery Spasm, Autonomic Dysfunction
The Effect of Autonomic Function on Coronary Vasomotion
Autonomic nerve function is involved in both blood pressure (BP) regulation and the pathogenesis of coronary artery spasm (CAS), but few studies have been published about the relationship between CAS and BP, with the exception of…
- Trial name
- NCT01877993
- Where
- 3 sites in South Korea
- Volunteers
- 2,169 people
- Sponsor
- Korea University
Brain Injury
Vasospasm in Pediatric Traumatic Brain Injury
The purpose of this study is to assess for vasospasm using Transcranial Doppler (TCD) and brain injury biomarkers, and evaluate neurocognitive outcome data in pediatric traumatic brain injury (TBI) patients who have experienced a…
- Trial name
- PTBI (NCT01461902)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Duke University
Subarachnoid Hemorrhage, Cerebral Vasospasm
Role of CT Perfusion in Predicting Poor Outcome After Subarachnoid Hemorrhage
Prospective evaluation of patients with subarachnoid hemorrhage (SAH) will be done by computed tomography angiography (CTA) and perfusion imaging (CTP) for any correlation between degree of vasospasm and perfusion deficit as well…
- Conditions
- Subarachnoid Hemorrhage, Cerebral Vasospasm, Delayed Cerebral Ischemia
- Trial name
- NCT03214705
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Assiut University
Acute Kidney Injury
Cystatin c: a Biomarker of AKI in Aneurysmal Subarachnoid Haemorrhage Patients
The goal of this observational study is to assess cystatin c as a predictive biomarker of early acute kidney injury in aneurysmal subarachnoid hemorrhage patients.
- Trial name
- NCT06635408
- Testing
- cystatin c
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Coronary Vasospasm, Coronary Microvascular Dysfunction
The NetherLands Registry of Invasive Coronary Vasomotor Function Testing (NL-CFT)
The goal of this registry is to collect data on patients referred for clinically indicated coronary vasomotor function test (CFT) and answer different questions on prevalence, safety and outcomes. The registry is observational.
- Conditions
- Coronary Vasospasm, Coronary Microvascular Dysfunction, Non-Obstructive Coronary Atherosclerosis
- Trial name
- NL-CFT (NCT06083155)
- Testing
- Coronary Function Test, Patient questionnaires
- Where
- 15 sites in Netherlands
- Volunteers
- 2,000 people
- Sponsor
- Radboud University Medical Center