Clinical trials: Ventilation Weaning
Brain Injury
Criteria of Extubation Failure of Brain Injured Patients. Elaboration of a Prognostic Score.
Identification of criteria associated with extubation failure of brain injured patients. Elaboration of a prognostic score of extubation failure of brain injured patients.
- Trial name
- GODWEAN (NCT02235376)
- Testing
- weaning trial of mechanical ventilation
- Where
- France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Clermont-Ferrand
Mechanical Ventilator Weaning, Critically Ill
Neurally Adjusted Ventilatory Assist for Weaning From Invasive Mechanical Ventilation in Critically Ill Children
The goal of this clinical trial is to compare weaning from mechanical ventilation in critically ill children. The main questions it aims to answer are: Will weaning with neurally adjusted ventilatory assist (NAVA) mode…
- Conditions
- Mechanical Ventilator Weaning, Critically Ill, Mechanical Ventilation, Neurally Adjusted Ventilatory Assist
- Trial name
- NCT06157593
- Testing
- NAVA
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Neonatal Respiratory Distress Syndrome, Intubation, Intratracheal
Chest Physiotherapy Technique Increasing Inspiratory Flow on Weaning From Non Invasive Ventilation
The main objective is to show by a randomised controled therapeutic trial comparing in two parallel open arms ( 50 infants x 2 = 100 infants) that the technique IIF decreases the duration of non invasive respiratory support in…
- Trial name
- KVNI (NCT02041676)
- Testing
- Chest physiotherapy, Usual surveillance
- Where
- France
- Volunteers
- 101 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Critically Ill
The Frequency of Screening and SBT Technique Trial: The FAST Trial
Background: The sickest patients who are admitted to an intensive care unit (ICU) often require assistance with their breathing.
- Trial name
- NCT02969226
- Testing
- Once daily screening, Twice daily screening, PS SBTs
- Where
- 17 sites in United States, Canada
- Volunteers
- 760 people
- Sponsor
- Unity Health Toronto
Respiration, Artificial
A SBT-based Protocol-directed Program in Difficult-to-Wean Patients
Weaning patients from a ventilator is one of the most challenging processes in an intensive care unit. The investigators aimed to determine whether spontaneous breathing trial (SBT)-based protocol-directed weaning combined with…
- Trial name
- NCT05035355
- Testing
- a weaning protocol
- Where
- China
- Volunteers
- 200 people
- Sponsor
- JinyanXing
Ventilator Weaning
Home-based Optimization of Mechanical Ventilation in Children
Some children who are born very early or have other congenital conditions may develop severe, long-term lung problems that make them need to use a breathing machine to live at home.
- Trial name
- HOMVent4Kids (NCT06055413)
- Testing
- Remote patient monitoring (RPM) bundle
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Distress Respiratory Syndrome, Weaning Failure
Pressure Support Ventilation Versus Neurally Adjusted Ventilatory Assist in Difficult to Wean Pediatric Patients
This study assessed the effects of NAVA versus Pressure Support Ventilation (PSV) on patient-ventilator interaction in pediatric patients with difficult weaning from mechanical ventilation after moderate Pediatric Acute…
- Trial name
- NCT04360590
- Testing
- pressure support ventilation versus neurally adjusted ventilatory assist
- Volunteers
- 12 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Pediatric Respiratory Diseases, Ventilator Weaning
WOB and Paediatric Mechanical Ventilation
Rationale: The most common approach to weaning infants and children is gradual reduction of ventilatory support ("traditional approach").
- Conditions
- Pediatric Respiratory Diseases, Ventilator Weaning, Respiration, Artificial, Respiratory Failure
- Trial name
- PedWOB (NCT05254691)
- Testing
- Sprinting
- Where
- Netherlands
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Acute Respiratory Failure
Continuous Positive Airway Pressure and Oxygen Concentration on Measurement of Rapid Shallow Breathing Index
To compare the rapid shallow breathing index (RSBI) values, the incidence of adverse reactions, and the predictive accuracy measured under 5 different ventilator strategies in the same patient group.
- Trial name
- NCT00632320
- Where
- Taiwan
- Volunteers
- 98 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Ventilator Weaning
Sedation and Weaning in Children Requiring Invasive Mechanical Ventilation
A UK multi-centre cluster randomised controlled trial to determine if a protocol-based intervention incorporating coordinated care with greater nursing involvement to managing sedation and ventilator weaning can reduce the…
- Trial name
- SANDWICH (NCT03673683)
- Testing
- SANDWICH protocol, Usual care
- Where
- 17 sites in United Kingdom
- Volunteers
- 10,498 people
- Sponsor
- Queen's University, Belfast
Respiratory Distress Syndrome (RDS), Bronchopulmonary Dysplasia (BPD)
Can Betamethasone Given After Birth Help Extremely Premature Babies Come Off Breathing Support Safely and Effectively?
The goal of this study is to determine if giving a steroid medication (specifically, betamethasone) after birth can help extremely premature babies (born before 28 weeks) come off breathing machines safely and reduce their risk…
- Trial name
- NCT07447739
- Testing
- Betamethasone
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Khang Nguyen
Mechanical Ventilation Complication
Non Invasive Mechanical Ventilation VERSUS Oxygen MASK
Conventional mechanical ventilation is a core feature of intensive care. Weaning and removal of endotracheal tube are crucial processes, which often account for a considerable part of Conventional mechanical ventilation total…
- Trial name
- NCT03259854
- Testing
- non invasive mechanical ventilation in pediatrics, oxygen mask
- Volunteers
- 104 people
- Sponsor
- Assiut University
Rapid Shallow Breathing
Prediction of Weaning Outcomes by Using Rate of Change of Rapid Shallow Breathing Index
This trial examines weaning outcomes using the rapid shallow breathing index rate.
- Trial name
- NCT00366197
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Atlantic Health System
Weaning Failure
Negative Pressure Ventilation in Paediatric Patients During Weaning
Negative pressure ventilation (NPV) represent a unique form of noninvasive ventilation using negative pressure by specialized cuirass, that evolve negative pressure on the front size of chest and partially abdomen and facilitate…
- Trial name
- NEGWEAN (NCT05035290)
- Testing
- Negative pressure ventilation
- Where
- Czechia
- Volunteers
- 200 people
- Sponsor
- Brno University Hospital
Respiratory Distress Syndrome
Comparing Weaning of Nasal Continuous Positive Airway Pressure (CPAP) From Preterm Infants
To compare the 2 methods of weaning of nasal continuous positive airway pressure (CPAP) in premature babies born between 26 and 32 weeks
- Trial name
- NCT02126501
- Testing
- Gradual pressure wean
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Maimonides Medical Center
Delayed Extubation, Postoperative Intensive Care
Factors Associated With Late Extubation in Postoperative Patients in the Surgical Intensive Care Unit
Timely removal of a breathing tube after surgery is an important part of recovery for patients admitted to the intensive care unit (ICU).
- Conditions
- Delayed Extubation, Postoperative Intensive Care, Mechanical Ventilation Weaning
- Trial name
- NCT07658456
- Testing
- No Intervention - Retrospective Observational Study
- Where
- Taiwan
- Volunteers
- 204 people
- Sponsor
- Kaohsiung Armed Forces General Hospital
Acute Severe Respiratory Failure, Acute Respiratory Distress Syndrome
WorldwidE AssessmeNt of Separation of pAtients From Ventilatory assistancE
WEAN SAFE (WorldwidE AssessmeNt of Separation of pAtients From ventilatory assistancE) is a multi-centre, prospective, observational, 4-week inception cohort study being carried out by the Acute Respiratory Failure section of…
- Trial name
- WEAN SAFE (NCT03255109)
- Where
- Belgium
- Volunteers
- 11,000 people
- Sponsor
- European Society of Intensive Care Medicine
Bronchiolitis, Respiratory Failure (Pediatric Patients)
Nurse-led High-flow Nasal Cannula Weaning Protocol in Pediatric Intensive Care Unit
Bronchiolitis is a leading cause of pediatric hospital admissions. Despite its limited clinical benefits, the use of HFNC in children with bronchiolitis is increasing.
- Conditions
- Bronchiolitis, Respiratory Failure (Pediatric Patients), High Flow Nasal Cannula
- Trial name
- NCT06621641
- Testing
- The new HFNC weaning protocol
- Where
- 6 sites in Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Dr. Behcet Uz Children's Hospital
Neonatal Respiratory Distress Syndrome, Extremely Low Birth Weight Infant (ELBW)
Effective Approaches & Strategies to Ease Off Nasal CPAP In Preterm Infants
Though Nasal Continuous Positive Airway Pressure (NCPAP) is a commonly used form of non-invasive neonatal respiratory support, the optimal method of weaning off NCPAP is not well established.
- Conditions
- Neonatal Respiratory Distress Syndrome, Extremely Low Birth Weight Infant (ELBW), BronchoPulmonary Dysplasia
- Trial name
- EASEOFFNCPAP (NCT02819050)
- Testing
- NCPAP
- Volunteers
- 80 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Mechanical Ventilation Complication
Mechanical Ventilator Weaning in Chronically Ventilated Patients
Mechanical ventilation is a commonly used life-saving hospital procedure for patients with severe breathing difficulty. Some patients have difficulty separating from the ventilator and need to be removed gradually.
- Trial name
- NCT06976554
- Testing
- weaning
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of California, Los Angeles