Clinical trials: Ventricular Arrythmia
Tachycardia, Atrioventricular Nodal Reentry
AV Nodal Reentrant Tachycardia Study
The purpose of this study is to determine/identify what mechanisms/factors are involved with regard to AV nodal reentrant tachycardia.
- Trial name
- AVNRT (NCT00618683)
- Testing
- Cardiac Invasive Electrophysiological Study
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Oklahoma
Brugada Syndrome (BrS), Ventricular Arrhythmia
Prospective Multicentre Observational Registry of Peri-procedural Anaesthesia, Sedation and Related Medication Exposure in Patients With Brugada Syndrome
The goal of this observational study is to evaluate the perioperative risk of malignant ventricular arrhythmias in adult patients diagnosed with Brugada Syndrome undergoing anaesthetic procedures.
- Conditions
- Brugada Syndrome (BrS), Ventricular Arrhythmia, Anesthesia, Sedation
- Trial name
- PROSP_BRUGANAE (NCT07655102)
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Hospital Clinic of Barcelona
Azithromycin Adverse Reaction, Covid19
The Effect of Azithromycin Use on Conduction System of Heart in COVID-19 Positive Children
Azithromycin (AZ) is used in the pediatric group in COVID-19 diseas. It has been reported to cause prolongation in the QT interval in adult age group.
- Conditions
- Azithromycin Adverse Reaction, Covid19, Long QT Syndrome
- Trial name
- NCT04699097
- Testing
- Azithromycin
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Kayseri City Hospital
Cardiovascular Diseases, Heart Diseases
Long QT Syndrome-Population Genetics and Cardiac Studies
To investigate the clinical, genetic and cardiologic aspects of the Long QT Syndrome, a predominantly hereditary disease with episodic malignant arrhythmias and sudden death, and a demonstrated gene linkage in a large pedigree.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Ventricular Arrhythmia, Long QT Syndrome
- Trial name
- LQTS (NCT00005176)
- Where
- United States
- Volunteers
- 2,125 people
- Sponsor
- University of Rochester
Cardiovascular Diseases, Heart Diseases
Predictors of Perioperative Cardiac Morbidity
To determine the predictors of perioperative cardiac morbidity and mortality in patients at high risk who underwent major noncardiac surgery with general anesthesia.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Myocardial Ischemia, Myocardial Infarction
- Trial name
- NCT00005197
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Left Bundle-Branch Block, Aortic Stenosis
Study on Heart Block Risks Using Outcome-Based Modeling
This study developed a prediction model for high-grade atrioventricular block (AVB) and complete left bundle branch block (CLBBB) following transcatheter aortic valve replacement (TAVR) in Chinese patients with aortic stenosis…
- Trial name
- SAVIOR (NCT07065123)
- Testing
- The population undergoing TAVR for aortic valve stenosis with outcomes of permanent pacemaker implantation and complete left bundle branch block after surgery
- Volunteers
- 112 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Supraventricular Tachycardia
Evaluation of the Pharmacokinetic Profile, Pharmacodynamic Effects, Acceptability and Tolerability of an Oral Amiodarone Solution of 15 mg / mL in Children With Supra Ventricular Tachycardia
The supra ventricular tachycardia is the most common symptomatic arrhythmia in pediatrics. Amiodarone is an antiarrhythmic drug used in this indication.
- Trial name
- Enteramio (NCT03153072)
- Testing
- Assess the absorption of oral amiodarone
- Where
- France
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Sudden Death
The Significance of Arrhythmias in Athletes
Athletes with complex ventricular arrhythmias are potentially at risk of sudden death. The aim of the study is to investigate the relevance of ventricular tachyarrhythmias induced by an exercise test in a retrospectively…
- Trial name
- Athlete (NCT00469794)
- Testing
- stress test
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Assaf-Harofeh Medical Center
Cardiovascular Diseases, Death, Sudden, Cardiac
Drug-Induced Sudden Death & Ventricular Arrhythmia
To investigate the relationship between the use of prescription drugs and the occurrence of ventricular arrhythmia and sudden death.
- Conditions
- Cardiovascular Diseases, Death, Sudden, Cardiac, Heart Diseases, Ventricular Arrhythmia
- Trial name
- NCT00102180
- Volunteers
- 31,000,000 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Arrhythmia, Acute Kidney Injuries
This is an Observational Study That Aims to Demonstrate Postoperative Risk Factors in Pediatric Cardiac Surgery
This retrospective observational study aims to identify risk factors for postoperative complications in children undergoing cardiac surgery at a tertiary hospital in Brazil.
- Conditions
- Arrhythmia, Acute Kidney Injuries, Sepsis, Pneumopathy
- Trial name
- PEDS-CARE (NCT06985082)
- Testing
- THERE IS NOT A INTERVENTION
- Volunteers
- 310 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Heart Block, Aortic Stenosis
Glucocorticoid Treatment in Transaortic Valve Replacement to Reduce the Incidence of Conduction Disturbances (GLUCO-TAVR).
The goal of this phase IV, randomized, controlled and open-label study is to assess the efficacy of peri-procedure glucocorticoid treatment in the prevention of conduction abnormalities and the need for pacemaker implantation in…
- Conditions
- Heart Block, Aortic Stenosis, Bundle-Branch Block
- Trial name
- GLUCO-TAVR (NCT06076824)
- Testing
- Methylprednisolone
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Hospital General Universitario de Alicante
Ventricular Arrhythmias
Evaluation of Electrocardiographic Measurements by High Density Electrode ECG
Cardiac electrical activity is detected on the body surface with conventional electrocardiography involving 12 leads (ECG 12). A limitation of the current ECG technique is that recordings are obtained from only 6 independent…
- Trial name
- ECG-HD (NCT04921501)
- Testing
- HD ECG, Conventional 12-lead ECG
- Where
- 11 sites in France, Monaco
- Volunteers
- 1,800 people
- Sponsor
- University Hospital, Bordeaux
Myocardial Infarction, Arrhythmia, Ventricular
MASTER II - Microvolt T Wave Alternans Testing for Risk Stratification of Post MI Patients
The purpose of the study is to determine the usefulness of Microvolt T Wave Alternans (MTWA) testing of patients that have had a heart attack and have decreased pumping ability of the lower chamber of their heart.
- Conditions
- Myocardial Infarction, Arrhythmia, Ventricular, Ischemic Cardiomyopathy
- Trial name
- NCT00305214
- Testing
- T Wave Alternans Test
- Where
- 47 sites in United States
- Volunteers
- 405 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Ventricular Fibrillation, Ventricular Tachycardia
Implantable Cardioverter Defibrillator (ICD) Support Groups and Veterans
In this study, we will compare the quality of life in veterans having ICD who attend the ICD support groups to those who do not.
- Conditions
- Ventricular Fibrillation, Ventricular Tachycardia, Sudden Cardiac Death
- Trial name
- NCT00846417
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Emory University
Aortic Valve Stenosis, AV Block
Prospective Arm of Conduct - Edwards SAPIEN3 PPI Registry
There are procedure related risk factors for permanent pacemaker implantation (PPI) that can be identified and assessed in a prospective cohort of 300 patients at high risk for PPI Prospective, multicenter, European registry in…
- Conditions
- Aortic Valve Stenosis, AV Block, Bundle-Branch Block
- Trial name
- Conduct-pro (NCT03715894)
- Testing
- transcatheter valve implantation
- Where
- 5 sites in Germany, Netherlands and 1 more
- Volunteers
- 300 people
- Sponsor
- Institut für Pharmakologie und Präventive Medizin
Congenital Heart Disease, Fallot Tetralogy
Prospective Evaluation of Programmed Ventricular Stimulation Before Pulmonary Valve Replacement in Patients With Tetralogy of Fallot
Severe pulmonary regurgitation is common in patients with Tetralogy of Fallot and results in progressive right ventricular dilatation and dysfunction.
- Conditions
- Congenital Heart Disease, Fallot Tetralogy, Ventricular Arrythmia, Pulmonary Valve Regurgitation
- Trial name
- NCT04205461
- Testing
- Programmed ventricular stimulation
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Paris Cardiovascular Research Center (Inserm U970)
Atrioventricular Nodal Reentry Tachycardia
Intracardiac Echocardiography Guided Slow Pathway Cryoablation
Atrioventricular nodal reentry tachycardia is best treated with catheter ablation aimed at disruption of conduction of the slow pathway.
- Trial name
- NCT05705297
- Where
- Slovenia
- Volunteers
- 30 people
- Sponsor
- University Medical Centre Ljubljana
Severe Aortic Valve Stenosis, High-degree AV Block
Infranodal Conduction Time During TAVR as Predictor of HAVB
Consecutive patients with high grade aortic stenosis undergoing transcatheter aortic valve replacement (TAVR) with a self-expanding valve (Medtronic CoreValve Evolut R® or Edwards Sapien S3®) without pre-existing pacemaker…
- Conditions
- Severe Aortic Valve Stenosis, High-degree AV Block, Left Bundle-Branch Block
- Trial name
- HOM-TAVI (NCT04128384)
- Testing
- Limited electrophysiologic study including measurements of HV- and AH-intervals pre- and post-TAVR
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University Hospital, Saarland
Ventricular Tachycardia, Cardiac Arrhythmia
MRI Assessment of Arrythmia Ablation Lesions
This study will evaluate the feasibility of visualization and characterization of arrhythmia ablation lesions by MRI immediately following standard ablation techniques.
- Trial name
- NCT02761343
- Testing
- MRI scan
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Children's National Research Institute
Ventricular Arrhythmia, Tachycardia
Enlighten Study: The EV-ICD Post Approval Registry
Medtronic is sponsoring Enlighten: The EV-ICD Post Approval Registry, to further confirm safety and effectiveness of EV-ICD in routine clinical practice, following commercial release of EV-ICD devices.
- Trial name
- NCT06048731
- Testing
- Defibrillation using EV-ICD
- Where
- 130 sites in United States, Austria and 22 more
- Volunteers
- 1,000 people
- Sponsor
- Medtronic