Clinical trials: Vision Loss
Uveitis, Scleritis
Causes of Visual Loss in Retinal Disease
This is a study of visual outcomes in retinal disease that seeks to identify the causes of visual loss. This data will be used to predict which patients are at risk of losing vision and how they can be better treated.
- Trial name
- NCT01613963
- Testing
- Immunosuppressive Agents
- Where
- 2 sites in United Kingdom
- Volunteers
- 2,000 people
- Sponsor
- Royal Surrey County Hospital NHS Foundation Trust
Obesity, Malignant Neoplasm
A Study to See if an iPhone Weight Management App Can Help Promote Weight Loss in Adolescents and Young Adults After a Stem Cell Transplant
This early phase I trial studies how well a behavioral weight loss intervention consisting of a smartphone application and coaching works for the promotion of weight loss in adolescents and young adults after a stem cell…
- Trial name
- NCT04453072
- Testing
- Interview, Media Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Jonsson Comprehensive Cancer Center
Headache, Urinary Incontinence
Pediatric Patient Experience on a Diagnostic Path
The trial will determine the impact of an information- and education-focused interventions on the anxiety levels, and patients' experiences as well as satisfaction of patients aged 10-14 and their caregivers during the MR…
- Conditions
- Headache, Urinary Incontinence, Growth Deficiency, Visual Impairment
- Trial name
- NCT05199363
- Testing
- Information leaflet, Educational movie, Demonstration
- Where
- Poland
- Volunteers
- 300 people
- Sponsor
- Children's Memorial Health Institute, Poland
Cerebral Visual Impairment, Refractive and Accommodative Disorders
Babies in Glasses; a Feasibility Study.
This is a feasibility study to begin investigating the possibility that early use of near vision glasses will improve vision in infants at risk of Cerebral Visual Impairment (CVI), leading to further improvement in other areas of…
- Conditions
- Cerebral Visual Impairment, Refractive and Accommodative Disorders, Hypoxic-Ischemic Encephalopathy, Premature Birth
- Trial name
- BiG (NCT05048550)
- Testing
- Near vision spectacles
- Where
- United Kingdom
- Volunteers
- 55 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Low Vision
Design and Clinical Evaluation of a Smartphone-based Low Vision Enhancement System
The primary objective is to compare the effectiveness and adverse side-effects of the virtual bioptic telescope and virtual projection screen in a new head-mounted video-based low vision enhancement system (LVES) with a wide…
- Trial name
- eLVES (NCT03728660)
- Testing
- Virtual bioptic magnification with large field of view, Full field magnification with small field of view
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Johns Hopkins University
Sensory Integration Disorder
Sensory Integration for Infants With Cortical Visual Impairment
Our study examines the effect of sensory integration training on sensory, motor and oculomotor skills in infants with cortical vision impairment .
- Trial name
- NCT05431647
- Testing
- Sensory integration therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Visual Impairment
Grip Effects of Power Ball in Children
A broad definition of visual impairment includes a wide continuum of visual function loss. Aspects of visual function include visual acuity, which is the capacity to resolve detail, and accommodation (capacity to concentrate)…
- Trial name
- NCT05976880
- Testing
- Conventional treatment of isometric hand grip training exercises, Conventional treatment along with power ball training
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
CHARGE Syndrome
Neurovisual Function in CHARGE Syndrome
The rationale of the study is to analyze visual function and correlate them with adaptive functions in patients with CHARGE syndrome in order to identify a pattern of specific indicators to enable better patient care
- Trial name
- NCT05764980
- Testing
- visual function evaluation
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Diabetes Mellitus, With Complications
New Concepts in Diabetic Macular Edema (DME)
Intravitreal ranibizumab injection procedure is simple and effective. In management of chronic DME there is no clear anatomical endpoint. Visual stability is the primary aim.
- Trial name
- DME (NCT04186702)
- Testing
- INTRAVITREAL RANIBIZUMAB INJECTION
- Volunteers
- 150 people
- Sponsor
- Ain Shams University
Septo-Optic Dysplasia, Agenesis of Corpus Callosum
Sleep Profile of Patients With Septo-optic Dysplasia
The aim of this study is to evaluate sleep of patients with septo-optic dysplasia compared to patients with an isolated disorder of peripheral visual system and patients with corpus callosum agenesis since both visus defict and…
- Conditions
- Septo-Optic Dysplasia, Agenesis of Corpus Callosum, Blindness
- Trial name
- NCT06262152
- Testing
- Actigraphy, blood and salivary sample, and sleep evaluation
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Vision Disability
Assessment of an Augmented Reality Low Visual Aid in Children and Young People With Visual Impairment
Approximately 24,500 children and young people (CYP) in England have a visual impairment (VI). VI refers to a loss of vision that cannot be corrected with glasses or contact lenses. Low vision aids (e.g.
- Trial name
- NCT05201482
- Testing
- SightPlus
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- Sheffield Children's NHS Foundation Trust
Retinal Hemangioblastoma, Von Hippel-Lindau Disease
Retrospective Case Series of Trans-scleral Cryotherapy for Retinal Hemangioblastoma
Background: Retinal hemangioblastoma (RH) is a tumor. It grows from the retina in the eye. It can threaten a person s vision. Trans-scleral cryotherapy is used to destroy the tumors and minimize the long-term risks of vision…
- Trial name
- NCT04458935
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- National Eye Institute (NEI)
Visual Impairment, Cerebral Visual Impairment
Promoting Psychophysical Well-being in Children and Adolescents With Visual Impairment
Visual impairment (VI) has significant implications not only for visual functioning, but also for the motor development, psychological well-being, and social participation of children and adolescents.
- Conditions
- Visual Impairment, Cerebral Visual Impairment, Visual Impairments
- Trial name
- VIPPSTAR_UNITN (NCT07703150)
- Testing
- Adapted Physical Activity Programme
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Università degli Studi di Trento
Usher Syndrome
Natural History of Photoreceptor Degeneration in USH1B: Clinical Parameters and Validation of Functional Vision Tests in MYO7A
Inherited retinal diseases (IRDs) are a group of degenerative disorders that cause progressive vision loss. Retinitis pigmentosa (RP) is the most common form, with a global prevalence of approximately 1 in 4,500.
- Trial name
- MYO7A (NCT07278843)
- Testing
- Vision tests, Retinal imaging, Questionnaires
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
Blindness, Visual Impairment
Physical Activity and Sports for People With Visual Impairments
Purpose of this study was to assess the relationship between the visual impairment degree and the level of children's fundamental motor skills, balance and bilateral coordination.
- Trial name
- NCT06318000
- Testing
- Balance test, bilateral coordination test, fundamental motor skills test
- Where
- Poland
- Volunteers
- 76 people
- Sponsor
- Józef Piłsudski University of Physical Education
Wolfram Syndrome
Efficacy Study of Daily Administration of VPA in Patients Affected by Wolfram Syndrome
Open label, phase II study non randomized single group assignment of 20 evaluable patients 13 years and older, over 37,5 kg body-weight, with sensorineural hearing loss of at least 20 dB at 8 kHz in high frequency average (HFA)…
- Trial name
- AUDIOWOLF (NCT04940572)
- Testing
- Depakine
- Where
- 2 sites in France, Spain
- Volunteers
- 23 people
- Sponsor
- Centre d'Etude des Cellules Souches
Healthy, Vision; Disorder, Loss
Associations Between Vision and Brain Function
Case-control studies and meta-analysis have reported that several ocular features, especially the thickness of the peripapillary retinal nerve fiber layer and visual acuity, are related to the brain degeneration and cognitive…
- Trial name
- NCT04226729
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Optic Neuritis, Optic Neuropathy
Prospective Evaluation of the 2022 Optic Neuritis Criteria When Optic Neuritis Is Suspected
Optic neuritis is an important cause of acute or subacute visual loss. In clinical practice, optic neuritis must often be distinguished from other optic neuropathies, retinal diseases, anterior-segment or ocular media disorders…
- Conditions
- Optic Neuritis, Optic Neuropathy, Visual Loss
- Trial name
- GX-ICON (NCT07623252)
- Where
- 9 sites in China
- Volunteers
- 500 people
- Sponsor
- First Affiliated Hospital of Guangxi Medical University
Usher Syndrome, Retinitis Pigmentosa
A Genetic Analysis of Usher Syndrome in Ashkenazi Jews
Hearing loss and loss of vision can be very harmful to the well-being and life of people who suffer from them. Usher syndrome is the name of a disease where people have both hearing loss and visual loss.
- Conditions
- Usher Syndrome, Retinitis Pigmentosa, Congenital Hearing Impairment
- Trial name
- NCT00016471
- Testing
- Audiogram, Electroretinogram
- Where
- United States
- Sponsor
- National Center for Research Resources (NCRR)
Cortical/Cerebral Visual Impairment, Cerebral Palsy
Examining the Effect of Eye Gaze Technology on Children With Cortical Visual Impairment
The goal of this study is to learn about eye gaze technology's use as an assessment and intervention of visual skills and the impact on occupational performance in children with cortical/cerebral visual impairment.
- Trial name
- NCT06067607
- Testing
- eye gaze technology
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Rockhurst University