Clinical trials: Vitamin A Deficiency
Vitamin A Deficiency, Iron-deficiency
Impact of Food-to-Food Fortified Cereal Products on Diet Quality in Eldoret, Kenya
The overall hypotheses is that a product designed with optimized nutritional characteristics, based on consumer preferences and leveraging local nutrient dense ingredients, can successfully deliver nutrition through sustainable…
- Trial name
- KenyaMPS (NCT05882682)
- Where
- Kenya
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Purdue University
Diarrhoea
Causes of Rotavirus Vaccine Failure in Zambian Children
Zambia recently introduced routine infant immunization against rotavirus - the most important cause of severe gastroenteritis and diarrhoea mortality in children.
- Trial name
- NCT01886833
- Where
- Zambia
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Centre for Infectious Disease Research in Zambia
Vitamin A Deficiency
Retinol Status in Preterm Infants and Mothers
Retinol and retinol binding protein were studied in the umbilical cord blood of 44 preterm infants with gestation age of < 30 weeks. Serum retinol and RBP levels were determined by enzyme-linked immunosorbent assay.
- Trial name
- NCT04780958
- Testing
- Serum retinol and RBP levels were determined by enzyme-linked immunosorbent assay.
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Iron Deficiency, Vitamin A Deficiency
Nutritional Status and Bouillon Use in Northern Ghana
This pilot aims to generate data that are critical for informing the design of a planned, more detailed study to evaluate the effect of multiple micronutrient (MN)-fortified bouillon cube on biomarkers of nutrient status of women…
- Conditions
- Iron Deficiency, Vitamin A Deficiency, Vitamin B 12 Deficiency, Folate Deficiency
- Trial name
- NCT04632771
- Testing
- N/A (observational study)
- Where
- Ghana
- Volunteers
- 995 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Hypovitaminosis, Vitamin A Deficiency
Impact of Maternal Supplementation With Dual Megadose of Vitamin A
The purpose of this study is to evaluate the effect of maternal supplementation with 400,000 IU of oral retinol palmitate in the post-partum, the nutritional situation of the binomial mother-child, on growth and morbidity of…
- Trial name
- NCT00742937
- Testing
- vitamin A
- Where
- Brazil
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Vitamin D Deficiency
Vitamin D Status and Its Influencing Factors in Zhejiang Province: A Multicenter Cross-Sectional Study
Vitamin D deficiency is a global public health problem, with an estimated 1 billion people affected worldwide, and large-scale systematic data for Zhejiang Province remain scarce.
- Trial name
- NCT07866391
- Where
- 2 sites in China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Vitamin A Deficiency
Effect of Vitamin A Supplementation on Immune Responses in Human Neonates
Vitamin A supplementation (VAS) significantly reduces all-cause mortality when given after 6 months of age, but has a null or detrimental effect when given between 1-5 months.
- Trial name
- NNVAS (NCT01476358)
- Testing
- Vitamin A (retinyl palmitate).
- Where
- The Gambia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Vitamin/Nutritional Deficiency, Neurobehavioral Manifestations
Walnuts, Long-Chain Polyunsaturated Fatty Acids and Adolescent Brain Development
Background: Adolescence is an important period for brain development as a result of increased synaptic plasticity. Omega-3 polyunsaturated fatty acids (n-3 PUFAs) are essential nutrients for brain development and protection…
- Trial name
- WALNUTs (NCT02590848)
- Testing
- Walnut intake
- Where
- Spain
- Volunteers
- 730 people, healthy volunteers welcome
- Sponsor
- Barcelona Institute for Global Health
Pneumonia, Vitamin D Deficiency
Kabul Vitamin D Supplementation Trial
Background: Pneumonia is the leading cause of childhood mortality, accounting for 19% of the 10.6 million deaths that occur each year1.
- Trial name
- NCT00548379
- Testing
- vitamin D
- Where
- 2 sites in Afghanistan
- Volunteers
- 3,048 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Vitamin A Deficiency, Vitamin A Toxicity
Liver and Bone Retinol Levels in Guatemalan Adolescents and Adults
Guatemala has enforced mandatory fortification of sugar with vitamin A (VA) since June 1974 and has led to a highly successful reduction in VA deficiency and associated disease. However, Ribaya-Mercado et al.
- Conditions
- Vitamin A Deficiency, Vitamin A Toxicity, Hypervitaminosis A
- Trial name
- GVAS (NCT04438200)
- Where
- 5 sites in Guatemala, United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Newcastle University
Vitamin A Deficiency
The Efficacy of Pro-vitamin A Biofortified Cassava on Vitamin A Status in Nigerian Preschool Children
The study comprises an open-label randomized controlled trial investigating the efficacy of consuming a daily ration of pro-vitamin A biofortified cassava on vitamin A status of Nigerian children, aged 3-4 years old (n=200).
- Trial name
- CASSAVITA II (NCT02627222)
- Testing
- Pro-vitamin A biofortified cassava, White cassava
- Where
- Nigeria
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Iron Deficiency, Anemia
The Efficacy of a Local Vitamin-C Rich Fruit (Guava) in Improving Iron Absorption From Mungbean Based Meals and Its Effect on Iron Status of Rural Indian Children (6-10 Years)
Iron deficiency is estimated to affect about one fifth of the world's population, and women and children are among the most severely affected.
- Trial name
- MUGUST_2 (NCT01191463)
- Testing
- Mung Bean Meal, Guava
- Where
- India
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Vitamin D Deficiency, Hypovitaminosis A
A Randomized Controlled Trial Testing The Effect Of A Multi-Nutrient Fortified Juice
The goal of this investigator-initiated study is to determine whether the fortification of orange juice with vitamin D, vitamin A, and vitamin E will enhance the vitamin D, vitamin A, and vitamin E status children ages 6-10 that…
- Conditions
- Vitamin D Deficiency, Hypovitaminosis A, Vitamin E Deficiency
- Trial name
- NCT01909063
- Testing
- Vitamin D, Vitamin D, Vitamin E, and Vitamin A, Control, 700 mg Calcium
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Boston University
Osteoarthritis, Osteoporosis
Development of a Non-invasive Assessment of Human Bone Quality Using Spatially Offset Raman Spectroscopy
In this study spatially offset Raman spectroscopy (SORS), which allows the collection of Raman spectra through turbid media, is being applied to collect Raman spectra of bone.
- Conditions
- Osteoarthritis, Osteoporosis, Osteogenesis Imperfecta, Rickets / Osteomalacia
- Trial name
- NCT02814591
- Testing
- spatially offset Raman spectrometer (SORS)
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- University College, London
Vitamin D Deficiency
Effects of Vitamin D Dose and Genotype of the Binding Protein in Infants and Children
The purpose of this study is to determine if the vitamin D binding protein genotype influences circulating vitamin D levels and if it may have functional consequences on vitamin D activity.
- Trial name
- VitaD (NCT01050387)
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- Yale University
Rickets
Study to Assess the Use of a Simple Lab Test to Screen for Rickets in Children
Some experts recommend that all breastfed babies receive supplemental vitamin D. The purpose of this study is to determine the rate of vitamin D use in breastfed babies, the recommendations of pediatricians regarding vitamin D…
- Trial name
- NCT00502866
- Where
- United States
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- Agency for Healthcare Research and Quality (AHRQ)
Vitamin A Deficiency
Vitamin A Equivalence of Plant Carotenoids in Children
Our objectives will be to test the following hypotheses and to make the following determinations: (1) The absorption and bio-conversion of provitamin A carotenes taken by children are different between spinach, Golden Rice, and…
- Trial name
- NCT00680212
- Testing
- dietary carotenoids, spinach, rice, and synthetic beta-carotene
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Tufts University
Development, Iron Deficiency
Zinc, Iron, Vitamin A and Psychosocial Care for Child Growth and Development
Many Indonesian infants are already iron deficient before they reach the age of six months, which also determines the high prevalence of anemia among under-five children.
- Conditions
- Development, Iron Deficiency, Zinc Deficiency
- Trial name
- NCT02319499
- Testing
- Zinc Alone, Iron and Zinc, Iron, Zinc and Vitamin A
- Where
- Indonesia
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Vitamin A Deficiency, Low Serum Retinol
Efficacy of β-carotene Biofortified Maize in Reducing Vitamin A Deficiency Among Children
The purpose of this cluster-randomized trial is to examine whether daily consumption of β-carotene biofortified maize flour can reduce the prevalence of vitamin A deficiency and improve the vitamin A status and among 4-8 year old…
- Trial name
- NCT01695148
- Testing
- β-Carotene Biofortified Maize Flour, White Maize Flour
- Where
- Zambia
- Volunteers
- 1,228 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Ulcerative Colitis, Vitamin D Deficiency
Observation of the Effect of Vitamin D Supplementation on Chronic Course of Patients With Ulcerative Colitis Based on Vitamin D Receptor Fok I Gene Polymorphism
Aims:Prospectively observe the effects of Vitamin D drops supplementation on the chronic course of ulcerative colitis patients, analyze whether the effect of Vitamin D drops on UC patients is affected by factors such as disease…
- Conditions
- Ulcerative Colitis, Vitamin D Deficiency, Vitamin D Supplement
- Trial name
- NCT04309058
- Testing
- Vitamin D drops
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University