Clinical trials: Vitiligo Vulgaris
Generalized Vitiligo
Bimatoprost 0.03% Solution With NB-UVB Versus Their Use With Fractional Carbon Dioxide Laser in Treatment of Generalized Vitiligo
Vitiligo is a chronic disorder of pigmentation characterized by the development of white macules on the skin due to loss of epidermal melanocytes.
- Trial name
- NCT03487042
- Testing
- Bimatoprost 0.03% ophthalmic solution
- Volunteers
- 40 people
- Sponsor
- Assiut University
Vitiligo
Improved Phototherapy in Patients With Vitiligo
Vitiligo is a common acquired depigmentation skin and mucosal disease in dermatology, with or without white hair. Vitiligo with white hair is difficult to treat.
- Trial name
- NCT05836441
- Testing
- Exposure to white patches, Exposure to edge of white patches and normal skin around white patches
- Where
- China
- Volunteers
- 110 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Vitiligo
HI-Light Pilot Trial for Vitiligo: Hand Held NB-UVB for Early or Focal Vitiligo at Home
This study is a small pilot randomised controlled trial (RCT) comparing hand-held NB-UVB light devices with placebo devices. These devices will be used by the participants to treat their vitiligo at home for a period of four…
- Trial name
- HI-Light (NCT01478945)
- Testing
- 311 nm NB-UVB light
- Where
- 2 sites in United Kingdom
- Volunteers
- 29 people
- Sponsor
- University of Nottingham
Non-segmental Vitiligo
An Open-label Single Center, Proof of Concept Study Evaluating the Efficacy of Roflumilast Foam 0.3% in Pediatric Patients With Non-Segmental Vitiligo (NSV)
An open-label single center, proof of concept study evaluating the efficacy of Roflumilast foam 0.3% in pediatric subjects with Non-Segmental Vitiligo (NSV)
- Trial name
- NCT07105254
- Testing
- Roflumilast topical 0.3% foam
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Derm Texas, PLLC
Vitiligo, Hearing Loss
Audiological Disturbances in Vitiligo
The purpose of this study is to determine wether vitiligo patients have more audiological abmnormalities, than the healthy population.
- Trial name
- NCT00484224
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Type 1 Diabetes, Autoimmune Diseases
Additional Autoimmune Diseases With Type 1 Diabetes in Pediatrics at Diabetes Diagnosis and During Follow-up
This study aims to describe the prevalence of additional autoimmune diseases and their specific antibodies at type 1 diabetes (T1D) diagnosis, and their incidence rate during follow-up, for children and adolescents.
- Conditions
- Type 1 Diabetes, Autoimmune Diseases, Hashimoto Disease, Graves Disease
- Trial name
- AADT1D (NCT04789993)
- Testing
- No intervention.
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Central Hospital, Nancy, France
Vitiligo, Child
Oral Tacrolimus vs Dexamethasone Micro-pulse Therapy in Pediatric Rapidly Progressing Vitiligo: A Multicenter RCT
This clinical study aims to compare the safety and effectiveness of two treatments-oral Tacrolimus capsules and Dexamethasone micro-pulse therapy-in children aged 4-12 years with rapidly progressing vitiligo.
- Conditions
- Vitiligo, Child, Progressive Disease
- Trial name
- NCT06900777
- Testing
- Tacrolimus, Dexamethasone
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Xijing Hospital
Metabolic Syndrome, Vitiligo
Metabolic Syndrome in Early Onset Versus Late Onset Vitiligo
This study aims at detection of possible associated metabolic syndrome with vitiligo and assessment of possible contribution of the age of onset of vitiligo.
- Trial name
- NCT03622320
- Testing
- Blood sample
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Cairo University
Non-Segmental Vitiligo (NSV)
Ruxolitinib Cream Combined With Corticosteroids for Progressive Non-Segmental Vitiligo: A Multicenter Real-World Study
This study is a prospective, multicenter, real-world observational study to assess the clinical efficacy and safety of topical 1.5% Ruxolitinib phosphate cream used in combination with systemic corticosteroids in a real-world…
- Trial name
- NCT07673640
- Testing
- 1.5% Ruxolitinib Phosphate Cream (Opzelura), Corticosteroid Therapy
- Where
- 20 sites in China
- Volunteers
- 300 people
- Sponsor
- ShanShan Li
NonSegmental Vitiligo
A Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Children (6 to < 12 Years Old) With Nonsegmental Vitiligo
The purpose of this study is to evaluate the efficacy and safety of ruxolitinib cream in children (6 to < 12 years old) with nonsegmental vitiligo.
- Trial name
- NCT06804811
- Testing
- Ruxolitinib Cream, Vehicle Cream
- Where
- 78 sites in Argentina, Austria and 12 more
- Volunteers
- 250 people
- Sponsor
- Incyte Corporation
Vitiligo
Topical Methotrexate with Fractional CO2 Laser in Treatment of Non Segmental Vitiligo
This prospective, within subject clinical trial aims to evaluate the efficacy of combining fractional CO2 laser with topical methotrexate versus topical methotrexate alone in treating non-segmental vitiligo.
- Trial name
- NCT06877455
- Testing
- Fractional CO2 laser assisted PDT
- Volunteers
- 50 people
- Sponsor
- Assiut University
Vitiligo
A Comparative Study on the Efficacy of Blue Light Emitting Diodes Therapy Versus Targeted Narrow Band UVB in Stable Non-segmental Vitiligo Patients.
A comparative study on the efficacy of blue light emitting diodes therapy versus targeted Narrow band UVB in stable non-segmental vitiligo patients.
- Trial name
- Nb-UVB (NCT07174024)
- Testing
- Narrow Band UVB Treatment, blue light emitting diode
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Vitiligo
Autologous Non-cultured Epidermal Cell Suspension Transplantation in the Treatment of Vitiligo
To observe the long-term efficacy and safety of autologous non cultured epidermal cell suspension transplantation in the treatment of vitiligo, analyze the correlation between cell density, type, and postoperative efficacy and…
- Trial name
- NCT07187882
- Testing
- Autologous Non-cultured Epidermal Cell Suspension transplantation
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking University People's Hospital
Stable Nonsegmental Vitiligo, Active Nonsegmental Vitiligo
A 52-Week Study of Ritlecitinib Oral Capsules in Adults and Adolescents With Nonsegmental Vitiligo (Active and Stable) Tranquillo
A 52-Week Study of Ritlecitinib Oral Capsules in Adults and Adolescents with Nonsegmental Vitiligo (Active and Stable) Tranquillo
- Trial name
- Tranquillo (NCT05583526)
- Testing
- Ritlecitinib
- Where
- 115 sites in United States, Australia and 13 more
- Volunteers
- 607 people
- Sponsor
- Pfizer
Vitiligo
Assess the Long Term Efficacy and Safety of Ruxolitinib Cream in Participants With Vitiligo
The purpose of this study is to evaluate the duration of response following withdrawal of ruxolitinib cream (Cohort A vehicle group), safety and maintenance of response with continued use of ruxolitinib cream in participants who…
- Trial name
- NCT04530344
- Testing
- ruxolitinib, Vehicle
- Where
- 84 sites in United States, Bulgaria and 6 more
- Volunteers
- 458 people
- Sponsor
- Incyte Corporation
Vitiligo
Phase II Clinical Trial of MH004 Ointment in Patients With Non-segmental Vitiligo
This is a multicenter, randomized, double-blind, vehicle-controlled phase II study of MH004 Ointment with a 28-week open-label long-term safety extension period.
- Trial name
- NCT07181187
- Testing
- MH004 Ointment, Vehicle Ointment
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Minghui Pharmaceutical (Hangzhou) Ltd
Vitiligo, Repigmentation
Topical Bimatoprost Solution 0.03%in Stable Vitiligo
Vitiligo is an acquired depigmentation disorder of great cosmetic importance, affecting 1-4% of the world's population. Phototherapy and topical agents such as corticosteroids, calcineurin inhibitors, and vitamin-D derivatives…
- Trial name
- NCT01202513
- Testing
- Bimatoprost 0.03% topical ophthalmic solution
- Volunteers
- 20 people
- Sponsor
- Gian Sagar Medical College and Hospital
Vitiligo - Macular Depigmentation
Comparative Study of Microneedling With Topical Minoxidil 5% ± NB-UVB in Stable Vitiligo"
This study is a randomized controlled trial comparing microneedling with topical minoxidil 5% versus microneedling with minoxidil combined with NB-UVB phototherapy in stable vitiligo.
- Trial name
- NCT07548918
- Testing
- microneedling with minoxidil 5% and NBUVB, Microneedling with Minoxidil5%
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sohag University
Crohn Disease, Ulcerative Colitis
Expanded Access to Upadacitinib
This is an expanded access program (EAP) for eligible participants. This program is designed to provide access to upadacitinib prior to approval by the local regulatory agency. Availability will depend on territory eligibility.
- Conditions
- Crohn Disease, Ulcerative Colitis, Idiopathic Arthritis (Including sJIA, pJIA, or JPsA), Atopic Dermatitis
- Trial name
- NCT04159597
- Testing
- Upadacitinib
- Sponsor
- AbbVie
Management of Stable Vitiligo
Effect of Platelet Rich Plasma on Outcome of Narrow Band UVB in Treatment of Vitiligo; Clinical and Histopathological Study
For each patient, one side of body will be treated with NB-UVB alone while the other side will be treated with NB-UVB therapy in addition to intradermal injection of PRP every 2 weeks.
- Trial name
- NCT06370650
- Testing
- platelet rich plasma, narrow band UVB
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University